On March 30, 2017, Katsuta, Ryo; Masada, Naoko; Shimodaira, Yuichiro; Ueda, Saeko; Yajima, Arata; Nukada, Tomoo published an article.COA of Formula: C5H10O3 The title of the article was Synthesis and stereochemistry of decarestrictines H and J. And the article contained the following:
The first synthesis of (7S,9R)-decarestrictine H and (7R,9R)-decarestrictine H as well as the improved synthesis of decarestrictine J were achieved. The overall yields of (7S,9R)-decarestrictines H and J were 20.9% each in nine to ten steps from (R)-Roche ester using a unified synthetic route via esterification with 3,3-ethylenedioxyhex-5-enoic acid and ring-closing metathesis, which were the key steps. The relative stereochem. of decarestrictine H was determined to be 7,9-syn by comparing the spectral data of the natural product and synthetic epimers of decarestrictines H. The experimental process involved the reaction of (R)-Methyl 3-hydroxybutanoate(cas: 3976-69-0).COA of Formula: C5H10O3
The Article related to decarestrictine h j synthesis stereochem, esterification synthesis decarestrictine h j, ring closing metathesis synthesis decarestrictine h j, Biomolecules and Their Synthetic Analogs: Other Bacterial and Fungal Metabolites and other aspects.COA of Formula: C5H10O3
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics