Tag: M.W=250-300

El-Sheekh, Mostafa M.; Deyab, Mohamed A.; Hasan, Reham S. A.; Abu Ahmed, Seham E.; Elsadany, Abdelgawad Y. published the artcile< Biological control of Fusarium tomato-wilt disease by cyanobacteria Nostoc spp.>, Computed Properties of 112-63-0, the main research area is Fusarium tomato wilt disease cyanobacteria Nostoc biol control; Antifungal activity; Cyanobacteria; Fusarium oxysporum; Tomatoes.

This study investigated the effect of foliar application of extract and culture of Nostoc calcicola and Nostoc linckia on the Fusarium oxysporum f. sp.lycopersici (FOL) that infects tomatoes (Solanum lycopersicum) plant in vitro and in vivo. Cyanobacterial isolates were isolated from saline soils at El-Hamoul and Seidy Salem locations Kafr Elsheikh, Egypt, and identified to be N. calcicola and N. linckia Bioactive compounds of extract were analyzed by Gas chromatog.-mass spectrometry (GC-MS). Dry weight, carotene, chlorophyll content, and total phenolic compounds of isolates were measured. Plant height, dry weight, fruit number, and fruit weight of tomatoes were estimated GC/MS anal. showed 49 and 35 bioactive compounds in extracts of N. calcicola and N. linckia, resp. N. calcicola possesses the highest values of chlorophyll a, carotenoid, and total phenol contents in dry weight compared with N. linckia. After 100 days of tomato growth, the results showed the highest yield of tomato fruits with the application of N. calcicola and N. linckia compared with the untreated plants and the plants which were infected with Fusarium, suggesting that N. calcicola and N. linckia can serve as a new bioagent for biol. control of the soil fungus Fusarium oxysporum f. sp. lycopersici (FOL).

Archives of Microbiology published new progress about Agrochemical foliar application methods. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Computed Properties of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Fuqiang; Liang, Zhong; Li, Yuxing; Wu, Zhimin; Yi, Zhengming published the artcile< Synthesis of waterborne polyurethane by inserting polydimethylsiloxane and constructing dual crosslinking for obtaining the superior performance of waterborne coatings>, COA of Formula: C19H34O2, the main research area is polydimethylsiloxane waterborne coating dual crosslinking.

Polydimethylsiloxane (PDMS) is usually used to obtain favorable performances of waterborne polyurethane (WPU) such as higher hardness, exceptional thermal stability and lower interfacial tension. However, there is always a problem that waterborne polyurethane (WPU) often performs weak tensile strength, lower tenacity and brittle property at room temperature when polydimethylsiloxane (PDMS) is embedded into the backbone of polyurethane. The study aims to address the problem by constructing dual crosslinking structure, namely introducing trimethylolpropane as an intramol. crosslinking agent into prepolymers and then adding waterborne polycarbodiimide (SK-400) as a post-crosslinking agent in order to further enlarge the degree of crosslinking and mainly make up for the shortcoming that mech. property decreases when polydimethylsiloxane (PDMS) was inserted into mol. chains. Initially a novel inner-crosslinking prepolymer (SiWPU) comprising polydimethylsiloxane need to be synthesized successfully by inserting trimethylolpropane into prepolymers. Then the sample SiWPU-3 was picked out as a matrix resin and dropwise added polycarbodiimide (SK-400) as a post-crosslinking agent into the matrix resin (C-SiWPU). As pH was gradually lowering following the evaporation of triethylamine in the emulsion (C-SiWPU), carboxyl groups (COOH) in prepolymers started to react with SK-400 (N=C=N) to form twofold crosslinking structure. When 0%, 2%, 4%, 6%, and 8 wt% of waterborne polycarbodiimide (SK-400) was incorporated into the solution, the tensile strengths are 47.8 MPa, 57.7 MPa, 65 MPa, 57.6 MPa and 54.5 MPa and the elongation at break 732%, 756%, 798%, 707% and 700%. The crosslinking d. of SiWPU-3 without the addition of waterborne polycarbodiimide (SK-400) is 3.86 × 10-3 mol/cm3. As 6 wt% of waterborne polycarbodiimide (SK-400) was added into the emulsion of SiWPU-3, the crosslinking d. of C-SiWPU-6 (6 wt% SK-400) is 6.19 × 10-3 mol/cm3. The films show excellent extensibility and exceptional tenacity. Hence, the emulsion is able to be applied in leather industry.

Composites, Part B: Engineering published new progress about Absorption. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Xiao, Haiyan; Wang, Jing; Saul, Alan; Smith, Sylvia B. published the artcile< Comparison of neuroprotective effects of monomethylfumarate to the sigma 1 receptor ligand (+)-pentazocine in a murine model of retinitis pigmentosa>, Product Details of C19H34O2, the main research area is monomethylfumarate pentazocine retinitis pigmentosa neuroprotection.

Activating the cell survival modulator sigma 1 receptor (Sig1R) delays cone photoreceptor cell loss in Pde6βrd10/J (rd10) mice, a model of retinitis pigmentosa. Beneficial effects are abrogated in rd10 mice lacking NRF2, implicating NRF2 as essential to Sig1R-mediated cone neuroprotection. Here we asked whether activation of NRF2 alone is sufficient to rescue cones in rd10 mice. Expression of antioxidant genes was evaluated in 661W cells and in mouse retinas after treatment with monomethylfumarate (MMF), a potent NRF2 activator. Rd10 mice were administered MMF (50 mg/kg) or the Sig1R ligand (+)-pentazocine (PTZ; 0.5 mg/kg) i.p. (every other day, P14-42). Mice were evaluated for visual acuity (optokinetic tracking response), retinal function (electroretinog.) and architecture (SD-OCT); histol. retinal sections were evaluated morphometrically. MMF treatment increased Nrf2, Nqo1, Cat, Sod1, and Hmox1 expression in vitro and in vivo. Visual acuity of (+)-PTZ-treated rd10 mice was similar to wild-type mice; however, MMF treatment did not alter acuity compared with nontreated rd10 mice. Cone electroretinog. b-wave amplitudes were greater in PTZ-treated than nontreated or MMF-treated rd10 mice. SD-OCT assessment of retinal thickness was greater in (+)-PTZ-treated mice vs. nontreated or MMF-treated rd10 mice. Morphometric assessment of the outer nuclear layer revealed approx. 18 cells/100μm retinal length in (+)-PTZ-treated rd10 mice, but only approx. 10 to 12 cells/100μm in MMF-treated and nontreated rd10 retinas. Activation of NRF2 using MMF, at least at our dosing regimen, is insufficient to attenuate catastrophic photoreceptor damage characteristic of rd10 mice. The data prompt investigation of addnl. mechanisms involved in Sig1R-mediated retinal neuroprotection.

Investigative Ophthalmology & Visual Science published new progress about Antioxidants. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Product Details of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Albers, Aaron E.; Garofalo, Albert W.; Drake, Penelope M.; Kudirka, Romas; de Hart, Gregory W.; Barfield, Robyn M.; Baker, Jeanne; Banas, Stefanie; Rabuka, David published the artcile< Exploring the effects of linker composition on site-specifically modified antibody-drug conjugates>, Quality Control of 112-63-0, the main research area is immunoconjugate HER2 antibody crosslinker maytansine antitumor; Aldehyde tag; Antibody–drug conjugate; Noncleavable linker.

In the context of antibody-drug conjugates (ADCs), noncleavable linkers provide a means to deliver cytotoxic small mols. to cell targets while reducing systemic toxicity caused by nontargeted release of the free drug. Addnl., noncleavable linkers afford an opportunity to change the chem. properties of the small mol. to improve potency or diminish affinity for multidrug transporters, thereby improving efficacy. We employed the aldehyde tag coupled with the hydrazino-iso-Pictet-Spengler (HIPS) ligation to generate a panel of site-specifically conjugated ADCs that varied only in the noncleavable linker portion. The ADC panel comprised antibodies carrying a maytansine payload ligated through one of five different linkers. Both the linker-maytansine constructs alone and the resulting ADC panel were characterized in a variety of in vitro and in vivo assays measuring biophys. and functional properties. We observed that slight differences in linker design affected these parameters in disparate ways, and noted that efficacy could be improved by selecting for particular attributes. These studies serve as a starting point for the exploration of more potent noncleavable linker systems.

European Journal of Medicinal Chemistry published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Gautam, Prashant; Kathe, Prasad; Bhanage, Bhalchandra M. published the artcile< Pd/C catalyzed phenoxycarbonylation using N-formylsaccharin as a CO surrogate in propylene carbonate, a sustainable solvent>, Application In Synthesis of 112-63-0, the main research area is palladium catalyzed phenoxycarbonylation formylsaccharin carbon monoxide surrogate sustainable solvent; phenyl ester preparation green synthesis phenoxycarbonylation aryl iodide.

This work reports the first Pd/C catalyzed phenoxycarbonylation of aryl iodides using N-formylsaccharin as a CO surrogate. Advantageously, the reaction could be carried out in propylene carbonate, an environmentally benign and sustainable polar aprotic solvent under CO surrogacy. Using N-formylsaccharin as a CO surrogate allows the usage of cheaper and readily available phenols as the coupling partner. A range of Ph esters could be synthesized under mild, co-catalyst free, ligand free and additive free conditions, including multi-substituted novel Ph esters. The Pd/C catalyst could be recycled up to four times with only a slight loss in activity. The reaction could be scaled up to gram scale synthesis.

Green Chemistry published new progress about Aromatic esters Role: SPN (Synthetic Preparation), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pervaje, Amulya K.; Tilly, Joseph C.; Detwiler, Andrew T.; Spontak, Richard J.; Khan, Saad A.; Santiso, Erik E. published the artcile< Molecular Simulations of Thermoset Polymers Implementing Theoretical Kinetics with Top-Down Coarse-Grained Models>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is thermoset polymer mol simulation.

Thermoset polymers are examples of chem. cured, network-forming materials whose bulk properties depend sensitively on formulation chem. and reaction conditions. In this work, we employ mol. dynamics simulations to model polyester-based urethane thermosets that are specifically targeted for coating applications. Parameterizing force field interactions with a statistical associating fluid theory (SAFT)-γ Mie approach in conjunction with corresponding state correlations; permits the facile development of effective models for our thermosetting system. We have devised a theor. model to fit exptl. kinetic data and implement a crosslinking algorithm that replicates the theor. kinetics. Our mol. simulations capture the cure kinetics regarding the reactions of the isocyanate group with the primary and secondary hydroxyl termini. Anal. of mol.-level connections that arise during crosslinking affords new information about network structure development. Predicted glass-transition temperatures and thermomech. properties agree well with exptl. data.

Macromolecules (Washington, DC, United States) published new progress about Activation energy. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Azzena, Ugo; Demartis, Salvatore; Melloni, Giovanni published the artcile< Electron-Transfer-Induced Reductive Cleavage of Phthalans: Reactivity and Synthetic Applications>, Quality Control of 112-63-0, the main research area is electron transfer phthalan reduction; isobenzofuran phthalan reductive electron transfer cleavage; isocoumarin preparation; coumarin preparation; benzopyran preparation; isobenzopyran preparation; naphthalenemethanol preparation; regiochem phthalan reductive electron transfer cleavage.

The behavior of phthalan (1,3-dihydroisobenzofuran) was investigated under conditions of electron transfer from alkali metals in aprotic solvents. Reaction with lithium in the presence of a catalytic amount of naphthalene in THF led to the reductive cleavage of an arylmethyl carbon-oxygen bond, with formation of a stable dilithium compound Trapping of this intermediate with several electrophiles (alkyl halides, carbonyl derivatives, CO2) was successful. The extension of this procedure to several substituted phthalans was investigated, and the regiochem. as well as the synthetic usefulness of these reactions are discussed.

Journal of Organic Chemistry published new progress about Electron transfer. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chouyia, Fatima Ezzahra; Fiorentino, Nunzio; Rouphael, Youssef; Ventorino, Valeria; Fechtali, Taoufiq; Visconti, Donato; Cozzolino, Eugenio; Idbella, Mohamed; Giordano, Maria; Fagnano, Massimo published the artcile< Assessing the effect of P-solubilizing bacteria and mycorrhizal fungi on tomato yield and quality under different crop rotations>, Formula: C19H34O2, the main research area is phosphorus solubilizing bacteria mycorrhizal fungi tomato yield quality crop.

Little is known about the effects of inoculation with beneficial microorganisms under diversified crop rotations on agronomic performance of the high-value vegetable crop tomato (Solanum lycopersicum L.). A greenhouse experiment was conducted to evaluate the interactive effect of crop precession with two native species, faba bean (Leguminosae) and barley (Graminaceae), and inoculations with com. arbuscular mycorrhizal fungi (AMF), and phosphate solubilizing Streptomyces roseocinereus MS1B15 on tomato plant growth, yield, fruit quality and the contents of various mineral nutrients. The overall results revealed that crop inoculation with S. roseocinereus MS1B15 significantly increased tomato growth and yield while crop precession showed no differences among tested treatments. Plant nutrient assimilation was significantly increased by both inoculations and was differentially modulated under faba bean and barley rotations. Furthermore, fruit quality demonstrated significant variations between treatments: whereas the inoculations significantly increased tomato vitamin C, crop rotations increased antioxidant compounds and organic acids. Overall, faba bean rotation combined with S. roseocinereus MS1B15 inoculation showed the best benefits for tomato plants, increasing most of the biometric variables evaluated in this study. Such combinations could be recommended as a sustainable and feasible model for tomato production

Scientia Horticulturae (Amsterdam, Netherlands) published new progress about Antioxidants. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

da Silva Oliveira, Emanuele Catarina; da Luz, Jose Maria Rodrigues; de Castro, Marina Gomes; Filgueiras, Paulo Roberto; Guarconi, Rogerio Carvalho; de Castro, Eustaquio Vinicius Ribeiro; da Silva, Marliane de Cassia Soares; Pereira, Lucas Louzada published the artcile< Chemical and sensory discrimination of coffee: impacts of the planting altitude and fermentation>, Application of C19H34O2, the main research area is coffee fermentation chem sensory discrimination.

Edaphoclimatic conditions, planting altitudes, soil, the microbiome of plants and fruits, genotypes, and postharvest processing are variables that contribute to the chem. and sensory quality of the coffee. Thus, the objective of this study was to evaluate the impacts of planting altitude and fermentation of fruits on the chem. and sensory quality of the coffee using NMR (NMR) and Linear Discriminant Anal. (LDA). Cherry coffees were harvested in eight points of altitudes between 826 and 1078.08 m. A completely randomized design with e planting altitudes, five fermentation processes, and five repetitions was performed. Lipids, trigonelline, citrate, and malate were the compounds that most contribute to the chem. discrimination of coffee in the altitudes below 969 m. While, in the high altitudes (> 1000 m), this discrimination was due to the HMF, quinic acid, caffeine, and formic acid, and the global notes of coffee beverages were higher than 80 points. In fermented coffee, the LDA of the chem. data indicates the formation of five clusters, showing how the compounds can suffer changes depending on the form of processing used in coffee. The best score of beverage was observed in samples of 1078.08 m under dry fermentation and only in samples of 969 m was observed a significant difference in the sensory score between spontaneous fermentation and induced fermentation Thus, coffee sensory scores were dependent on planting and fermentation methods and NMR and LDA techniques proved important in chem. and sensory discrimination of coffees.

European Food Research and Technology published new progress about Beverages. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Srankova, Maria; Dvorak, Ales; Martinek, Marek; Sebej, Peter; Klan, Petr; Vitek, Libor; Muchova, Lucie published the artcile< Antiproliferative and Cytotoxic Activities of Fluorescein-A Diagnostic Angiography Dye>, Category: esters-buliding-blocks, the main research area is fluorescein diagnostic angiog dye antiproliferative cytotoxicity cancer human; carbon monoxide; fluorescein; irradiation; metabolism; proliferation; singlet oxygen; viability.

Fluorescein is a fluorescent dye used as a diagnostic tool in various fields of medicine. Although fluorescein itself possesses low toxicity, after photoactivation, it releases potentially toxic mols., such as singlet oxygen (1O2) and, as we demonstrate in this work, also carbon monoxide (CO). As both of these mols. can affect physiol. processes, the main aim of this study was to explore the potential biol. impacts of fluorescein photochem. In our in vitro study in a human hepatoblastoma HepG2 cell line, we explored the possible effects on cell viability, cellular energy metabolism, and the cell cycle. We observed markedly lowered cell viability (&30%, 75-2400μM) upon irradiation of intracellular fluorescein and proved that this decrease in viability was dependent on the cellular oxygen concentration We also detected a significantly decreased concentration of Krebs cycle metabolites (lactate and citrate < 30%; 2-hydroxyglutarate and 2-oxoglutarate < 10%) as well as cell cycle arrest (decrease in the G2 phase of 18%). These observations suggest that this photochem. reaction could have important biol. consequences and may account for some adverse reactions observed in fluorescein-treated patients. Addnl., the biol. activities of both 1O2 and CO might have considerable therapeutic potential, particularly in the treatment of cancer. International Journal of Molecular Sciences published new progress about Angiography imaging agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics