Tag: M.W=250-300

Naushad, Mu.; Ahamad, Tansir; Khan, Mohammad Rizwan published the artcile< Fabrication of magnetic nanoparticles supported ionic liquid catalyst for transesterification of vegetable oil to produce biodiesel>, Electric Literature of 112-63-0, the main research area is butylimidazole magnetic nanoparticle ionic liquid transesterification catalyst.

In the present study, we have fabricated novel magnetic ionic liquid based nanocomposites using 1-butylimidazole, 3-bromopropyl-trimethoxysilane and NiFe2O4 nanoparticles. NiFe2O4@-BMSIHSO4 was synthesized from NiFe2O4@-BMSI Br via ion-exchange process. The fabricated nanocomposites were characterized by various anal. techniques. The surface area was determined using N2 adsorption-desorption anal. and the BET surface area of NiFe2O4@BMSI Br and NiFe2O4@BMSI HSO4 was noted to be 89.21 and 87.21 m2/g, resp. The fabricated nanocomposites were used as catalyst for the transesterification of palm oil (VO) for the production of biodiesel. The results revealed that NiFe2O4@BMSI HSO4 exhibited better performance in terms of biodiesel yield; a maximum i.e. 86.4% yield was obtained using NiFe2O4@BMSI HSO4 while in the case of NiFe2O4@BMSI Br, about ∼74.6% yield was found with 5% weight/weight catalyst loading, 353 K and to CH3OH ratio of 1:12 in 8 h. The reusability of the catalyst results revealed that the catalytic activity of the catalysts still remained about 92.7% and 88.1% with NiFe2O4@BMSI HSO4 and NiFe2O4@BMSI Br, resp. after six cycles which may be accredited to the handling loss during the manipulation process.

Journal of Molecular Liquids published new progress about Ion exchange. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Xie, Qinglong; Zhu, Huiyun; Xu, Pan; Xing, Kainan; Yu, Shangzhi; Liang, Xiaojiang; Ji, Weirong; Nie, Yong; Ji, Jianbing published the artcile< Transesterification of methyl oleate for sustainable production of biolubricant: Process optimization and kinetic study>, Product Details of C19H34O2, the main research area is biolubricant process optimization sustainable production methyl oleate transesterification.

Trimethylolpropane fatty acid triester (TFATE) is a promising biolubricant as an environmentally friendly substitute to conventional mineral-based lubricants. However, the issues of extensive energy consumption from vacuum maintenance and feedstock saponification caused by strong alk. catalysts exist in current TFATE-based biolubricant synthesis. Here, sustainable production of biolubricant was achieved with Me oleate (MO) from non-edible oil sources as the feedstock and moderate alk. K2CO3 as the catalyst. Nitrogen gas stripping method instead of vacuum was adopted for methanol removal. The effects of agitation speed, N2 flow rate, catalyst amount, MO to trimethylolpropane (TMP) molar ratio and temperature on MO conversion and TFATE selectivity were examined The TFATE selectivity reached 95.6% under the optimized conditions. Leaching tests indicated neglectable K2CO3 dissolution in reaction products. The kinetic parameters for the three consecutive transesterification reactions were calculated In addition, the synthesized biolubricants exhibit low acid value and volatility, moderate iodine value, superior thermal stability, and good rheol. and frictional properties.

Industrial Crops and Products published new progress about Acid number. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Product Details of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Huang, Yande; Yu, Jaehoon; Bentrude, Wesley G. published the artcile< Study of the Conformational Equilibria of 2-Z-3-Methyl-1,3,2-oxazaphosphorinanes. Steric and Stereoelectronic Influences on the Orientation of the Me2N Substituent on Three-Coordinate Phosphorus>, Electric Literature of 112-63-0, the main research area is conformation equilibrium oxazaphosphorinane steric stereoelectronic effect.

The conformations of a series of 1,3,2-oxazaphosphorinanes containing three-coordinate phosphorus I (R = OMe, (CF3)2CHO, NMe2, R1 = R2 = H, Me; R = same, R1 = CMe3, R2 = H) have been determined by the use of 1H, 31P, and 13C NMR spectroscopy. The rings were substituted at ring nitrogen, N(3), with a Me group to compare its effect on conformational energies with those of 1,3,2-oxazaphosphorinanes reported earlier that featured a larger substituent at N(3), Ph or i-Pr. Quite expectedly, like those rings previously studied with Ph or i-Pr at N(3), a MeO or (CF3)2CHO substituent at phosphorus has a strong preference to be axial on a chair-form ring I (R = OMe, (CF3)2CHO, R1 = R2 = H, Me) and cis-I (R = OMe, (CF3)2CHO, R1 = CMe3, R2 = H), or pseudoaxial on a ring in a twist/boat conformation, trans-I (R = OMe, R1 = CMe3, R2 = H). However, when Me2N is attached to phosphorus, the newly studied N(3)Me rings display a chair-chair conformational equilibrium, II ⇄ III, with the Me2N equatorial ring, III, mildly dominant. This contrasts with ratios of 17/83 and 20/80 for the corresponding N(3)Ph analogs. The observed change in the free energy of the equilibrium II ⇄ III, 1.2-1.3 kcal/mol, is ascribed to the dominant influence of a decrease in repulsion experienced in conformation III between the equatorial Me2NP and the smaller Me at N(3) (Me2N(eq)/N(3)Me destabilization) compared to that experienced with the N(3)Ph and N(3)-i-Pr analogs. This steric influence of N(3) substituents on the equilibrium II ⇄ III is opposite to that found for four-coordinate phosphorus containing 1,3,2-oxazaphosphorinanes in which Me2NP(ax)/N(3)Ph repulsions that destabilize II appear to be dominant.

Journal of Organic Chemistry published new progress about Equilibrium. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lin, Yuanbin; Liang, Chungen published the artcile< Convenient synthetic procedures for 2-bromothiophene>, Application In Synthesis of 112-63-0, the main research area is bromothiophene preparation; thiophene bromination pyridine hydrobromide perbromide.

The reaction of thiophene with pyridine hydrobromide perbromide in 48% hydrobromic acid and tetrachloromethane gives 90.4% 2-bromothiophene.

Xiangtan Daxue Ziran Kexue Xuebao published new progress about Bromination. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Nakamura, Shinsuke; Mukudai, Yoshiki; Chikuda, Junichiro; Zhang, Meilin; Shigemori, Hideyuki; Yazawa, Kazunaga; Kondo, Seiji; Shimane, Toshikazu; Shirota, Tatsuo published the artcile< Combinational anti-tumor effects of chemicals from Paeonia lutea leaf extract in oral squamous cell carcinoma cells>, HPLC of Formula: 112-63-0, the main research area is Paeonia lutea leaf extract antitumor oral squamous cell carcinoma; Gallic acid methyl ester; Paeonia lutea; paeoniflorin; pentagalloyl glucose; squamous cell carcinoma.

We identified chem. components that exhibited antitumor activity against oral squamous cell carcinoma (OSCC) cells and examined their effective concentrations and additive and/or synergistic effects in combinational usage on the proliferation, apoptosis and cell cycle of OSCC cells. Using high-performance liquid chromatog., NMR spectroscopy and electrospray ionization-mass spectrometry, we identified the main chem. components of the methanol extracts from Paeonia lutea. We investigated the pharmaceutical effects of those components on the proliferation, apoptosis, and cell cycle of an OSCC cell line, SAS, using the tetrazolium salt 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazolium bromide (MTT) and caspase assays, as well as flow cytometry cell cycle anal. We also examined the effects of those components on the mitogen-activated protein kinase signal transduction pathway by western blotting. Finally, the effects on normal human epidermal keratinocyte cells were also examined in similar experiments Three chems. have been identified in P. lutea leaves using high performance liquid chromatog.: gallic acid Me ester (GAME), pentagalloyl glucose (PGG) and paeoniflorin (PF). Both GAME and PGG significantly suppressed cell proliferation, and their combined effects were synergistic, while the effect of PF was minimal. However, those chems. did not induce apoptosis. Cell cycle and western blotting anal. showed that the suppressive effects on cell proliferation resulted from G2 arrest and the suppression of phosphorylation of Akt/PKB. No effect was identified on normal human epidermal keratinocyte cells. These results indicate that GAME and PGG are the main chem. components of P. lutea leaves that have potential anti-cancer therapeutic effects.

Anticancer Research published new progress about Antitumor agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zeng, Ruiming; Chen, Ying; Zhang, Li; Tan, Jianbo published the artcile< R-RAFT or Z-RAFT? Well-Defined Star Block Copolymer Nano-Objects Prepared by RAFT-Mediated Polymerization-Induced Self-Assembly>, COA of Formula: C19H34O2, the main research area is RAFT polymerization copolymer nanoobject polymerization.

Reversible addition-fragmentation chain transfer (RAFT)-mediated polymerization-induced self-assembly (PISA) has served as a versatile platform for the large-scale preparation of block copolymer nano-objects with a diverse set of morphologies. However, almost all PISA formulations are focused on the syntheses of linear block copolymers rather than star block copolymers. Owing to the asym. structure of the RAFT agent, herein, we report a direct comparison between Z-RAFT (the nonfragmenting group attached to the core) and R-RAFT (the fragmenting group attached to the core) strategies for preparing well-defined star block copolymer nano-objects via RAFT-mediated PISA. We showed that the Z-RAFT strategy is a more suitable strategy for the preparation of star block copolymer nano-objects without compromising the control over the mol. weight and morphol. A binary mixture of Z-type and R-type tetrafunctional macro-RAFT agents was used to control the morphologies of star block copolymer assemblies. The effect of numbers of the RAFT group on polymerization kinetics and morphologies of block copolymer nano-objects was also investigated in detail. Finally, (ABC)4 four-arm star triblock copolymer vesicles were prepared by seeded RAFT dispersion polymerization of solvophobic and solvophilic monomers using (AB)4 four-arm star diblock copolymer vesicles as seeds. This research not only expands the scope for preparing well-defined star block copolymer nano-objects but also provides important insights into the effect of the polymer architecture on RAFT-mediated PISA.

Macromolecules (Washington, DC, United States) published new progress about Binary mixtures. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hong, Zhongyang; Zhang, Xianzheng; Zhang, Tianjing; Hu, Ling; Liu, Ruijin; Wang, Pan; Wang, Han; Yu, Qianqian; Mei, Dan; Xue, Ziyang; Zhang, Feng; Zhang, Lingling published the artcile< The ROS/GRK2/HIF-1α/NLRP3 pathway mediates pyroptosis of fibroblast-like synoviocytes and the regulation of monomer derivatives of paeoniflorin>, SDS of cas: 112-63-0, the main research area is .

Hypoxia is an important factor in the development of synovitis in rheumatoid arthritis (RA). The previous study of the research group found that monomeric derivatives of paeoniflorin (MDP) can alleviate joint inflammation in adjuvant-induced arthritis (AA) rats by inhibiting macrophage pyroptosis. This study revealed increased levels of hypoxia-inducible factor- (HIF-) 1α and N-terminal p30 fragment of GSDMD (GSDMD-N) in fibroblast-like synoviocytes (FLS) of RA patients and AA rats, while MDP significantly inhibited their expression. Subsequently, FLS were exposed to a hypoxic environment or treated with cobalt ion in vitro. Western blot and immunofluorescence anal. showed increased expression of G protein-coupled receptor kinase 2 (GRK2), HIF-1α, nucleotide-binding oligomerization segment-like receptor family 3 (NLRP3), ASC, caspase-1, cleavedcaspase- 1, and GSDMD-N. Electron microscopy revealed FLS pyroptosis after exposure in hypoxia. Next, corresponding shRNAs were transferred into FLS to knock down hypoxia-inducible factor- (HIF-) 1α, and in turn, NLRP3 and western blot results confirmed the same. The enhanced level of GSDMD was reversed under hypoxia by inhibiting NLRP3 expression. Knockdown and overexpression of GRK2 in FLS revealed GRK2 to be a pos. regulator of HIF-1α. Levels of GRK2 and HIF-1α were inhibited by eliminating excess reactive oxygen species (ROS). Furthermore, MDP reduced FLS pyroptosis through targeted inhibition of GRK2 phosphorylation. According to these findings, hypoxia induces FLS pyroptosis through the ROS/GRK2/HIF-1α/NLRP3 pathway, while MDP regulates this pathway to reduce FLS pyroptosis.

Oxidative Medicine and Cellular Longevity published new progress about 112-63-0. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, SDS of cas: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Krysan, Damian J. published the artcile< A dramatic reversal of facial selectivity in the Sharpless asymmetric dihydroxylation of a sterically hindered 3-methylidene-benzofuran>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is benzofuran asym dihydroxylation catalyst; dihydroquinine catalyst asym osmylation; dihydroquinidine catalyst asym osmylation; osmylation asym catalyst dihydroquinine dihydroquinidine.

Reversal of π-facial selectivity in the osmium-catalyzed asym. dihydroxylation (AD) of an exocyclic olefin I was reported. Switching from a phthalazine-linked ligand (DHQ2PHAL or DHQD2PHAL) to a pyrimidine-linked ligand (DHQ2PYR or DHQD2PYR) led to the opposite enantiomer using the same pseudo-enantiomer of the cinchona alkaloid.

Tetrahedron Letters published new progress about Dihydroxylation catalysts, stereoselective. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hu, Yaofang; Tang, Gang; Luo, Yunjun; Chi, Shumeng; Li, Xiaoyu published the artcile< Glycidyl azide polymer-based polyurethane vitrimers with disulfide chain extenders>, Computed Properties of 112-63-0, the main research area is glycidyl azide polyol based polyurethane vitrimer property.

The glycidyl azide polymer (GAP) is an important type of energetic polymer and is considered to be the most promising candidate for polymeric binders for next generation solid propellants. However, the most outstanding obstacle for the wide application of GAP is its low mech. properties, which is usually overcome by incorporating it into polyurethanes (PUs) as a soft segment. Herein, we report the preparation of a series of GAP-based PU vitrimers (GAPUVs), with GAP, 2-hydroxyethyl disulfide (HEDS), and trimethylolpropane (TMP) as the soft segment, chain extender and crosslinker, resp. The crosslinking d. and composition of the resultant thermosetting GAPUVs were optimized to significantly improve the mech. properties, which were clearly superior to their linear counterparts and most examples from the literature. More interestingly, the incorporation of dynamic disulfide bonds in the network not only endowed the GAPUVs with decent mech. properties, but also marked healing ability upon mild heating and thermo-reprocessability. This allowed the fabrication of healable composites from GAPUVs and aluminum powders, with a healing efficiency above 95%. Addnl., the thermo-exchangeable disulfide linkage in the GAPUVs allowed the full recovery of the loaded fillers by simply heating the composite in a solvent.

Polymer Chemistry published new progress about Crosslink density. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Computed Properties of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Aparna, P.; Kothari, Seema; Banerji, Kalyan K. published the artcile< Kinetics and mechanism of oxidation of hydroxy acids by pyridinium hydrobromide perbromide>, Application In Synthesis of 112-63-0, the main research area is oxidation hydroxy acid pyridinium hydrobromide perbromide.

The oxidation of glycolic, lactic, mandelic and malic acids by pyridinium hydrobromide perbromide (PHPB) in acetic acid-water mixture (3:7, volume/volume) gives oxo acids. The reaction is first-order each in PHPB and the hydroxy acid. Addition of pyridinium hydrobromide does not affect the rate, indicating that PHPB itself is the reactive oxidizing species. The oxidation of α-deuteriomandelic acid shows the presence of a primary kinetic isotope effect (kH/kD = 5.07). The reaction does not exhibit a solvent isotope effect [k(H2O)/k(D2O) = 1.01]. The rate decreases with an increase in acetic acid content in the solvent mixture A mechanism involving hydride ion transfer to the oxidant is proposed.

Indian Journal of Chemistry, Section A: Inorganic, Bio-inorganic, Physical, Theoretical & Analytical Chemistry published new progress about Isotope effect. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics