Tag: 100-200

Studies on changes in scalp odor of women with aging was written by Yokoyama, Hiromi;Mochizuki, Yuji;Kaneko, Yuki;Fukushima, Kazuhiro;Takahashi, Kyoko. And the article was included in Nippon Aji to Nioi Gakkaishi in 2021.Recommanded Product: 706-14-9 This article mentions the following:

In recent years, people’s awareness of changes in body odor associated with aging has increased, and interest in odor etiquette has increased. The author have so far conducted research on changes in body odor in women with aging and in the course of further awareness surveys, it became clear that many women felt that their scalp odor had changed with age. However, although research on scalp odor has been conducted, research on changes in scalp odor with age has not made much progress. Therefore, in this study, the author evaluated the scalp odor of women in their tens to 50s, and investigated changes in women’s scalp equipment with aging. In the experiment, the researchers used many compounds, for example, 5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9Recommanded Product: 706-14-9).

5-Hexyldihydrofuran-2(3H)-one (cas: 706-14-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: 706-14-9

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tetrahydro- and octahydropyrido[1,2-a]pyrimidin-4-ones was written by Yale, Harry L.;Spitzmiller, Ervin R.. And the article was included in Journal of Heterocyclic Chemistry in 1976.Related Products of 14667-47-1 This article mentions the following:

The catalytic hydrogenation of the pyridopyrimidines I [R = Me, Pr, Ph; R1 = H, Me; R2 = 9-Me, 8-Me, 9-HO; R = Me, R1 = H, R2 = 9-CO2H, 9-CO2Et, 9-CONH2, 9-CONHMe, 9-CO2Me, 9-CONH(CH2)3NMe2] gave II and fully saturated, octahydro analogs. In the PMR spectra of II [R = Me, R1 = H, R2 = 9-CO2H, 9-CO2Et, 9-CO2Me, 9-CONH2, 9-CONHMe, CONH(CH2)3NMe2] there was evidence of a facile 1,3-prototropic shift of the proton from position-9 to position-1, resulting in equilibrium between tautomeric species. The ratio of tautomers present at equilibrium, with the esters, favored the enamine conformation, but with both the carboxylic acid and the amides the imine structure predominated. Supportive evidence for the enamine structure with the esters was derived also from the ir spectra. Alkylation of the anion derived from the tetrahydro 9-carbomethoxy derivative with NaH led exclusively to derivatives of the 6,7,8,9-tetrahydro system. In the experiment, the researchers used many compounds, for example, Methyl 2-aminonicotinate (cas: 14667-47-1Related Products of 14667-47-1).

Methyl 2-aminonicotinate (cas: 14667-47-1) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Related Products of 14667-47-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Design, synthesis, and biological evaluation of imidazo [1,2-a] pyridine derivatives as acetylcholinesterase inhibitors was written by Boppana, Sriramamurthy;Ahmed, Faiyaz;Chandra, Narendra Sharath J. N.;Rangappa, Kanchugarakoppal S.;Urooj, Asna. And the article was included in Journal of Pharmacy Research in 2010.Recommanded Product: Methyl 2-aminonicotinate This article mentions the following:

To explore novel and effective drugs for the treatment of Alzheimers disease(AD), a series of inhibitors of acetylcholinesterase (AChE) were designed based on the Structure-based generation of a novel series of AchE inhibitors were carried out with crystal structure of acetylcholine esterase complexed with choline (PDB: 2HA3) obtained from protein data. Among synthesized inhibitor 7(a-e) exhibited good potency in enzyme inhibitory potency AChE: IC= 55 ± 0.53M, 73 ± 0.37M, and 51 ± 0.37M, 73 ± 0.40M, 48±0.75M, 7b and 7C also showed moderate to good activity in acetylcholinesterase assay in vitro using different sources of acetylcholinesterase studied (rat brain, human serum and elec. eel). In the experiment, the researchers used many compounds, for example, Methyl 2-aminonicotinate (cas: 14667-47-1Recommanded Product: Methyl 2-aminonicotinate).

Methyl 2-aminonicotinate (cas: 14667-47-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: Methyl 2-aminonicotinate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of the related substances of Nilotinib hydrochloride was written by Huang, Junjie;Liao, Mingyi;Guo, Qi;You, Qidong. And the article was included in Zhongguo Yiyao Gongye Zazhi in 2016.Electric Literature of C10H13NO2 This article mentions the following:

To strengthen the quality control of Nilotinib hydrochloride, five related substances of Nilotinib were synthesized based on its synthetic process. These substances, including 3-[4-(pyridin-3-yl) pyrimidin-2-ylamino]-4-methylbenzoic acid (A), 3-[4-(pyridin-3-yl) pyrimidin-2-ylamino]-N-[3-(4-ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl) phenyl]-4-methylbenzamide (B), 3-[4-(pyridin-3-yl) pyrimidin-2-ylamino]-N-[3-(trifluoromethyl)-5-(1H-imidazol-1-yl) phenyl]-4-methylbenzamide (C), 3-[4-(pyridin-3-yl) pyrimidin-2-ylamino]-N-[3-(trifluoromethyl)-5-(2,4-dimethyl-1H-imidazol-1-yl) phenyl]-4-methylbenzamide (D), 3-[4-(pyridin-3-yl) pyrimidin-2-ylamino]-N-[3-(trifluoromethyl)-5-(5-methyl-1H-imidazol-1-yl) phenyl]-4-methylbenzamide (E), were synthesized and their structures were confirmed by MS and ¹H NMR. In the experiment, the researchers used many compounds, for example, Ethyl 3-amino-4-methylbenzoate (cas: 41191-92-8Electric Literature of C10H13NO2).

Ethyl 3-amino-4-methylbenzoate (cas: 41191-92-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Electric Literature of C10H13NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Toxicity of citronella essential oil and its nanoemulsion against the sawtoothed grain beetle Oryzaephilus surinamensis (Coleoptera: Silvanidae) was written by Gharsan, Fatehia Nasser;Kamel, Walaa Mohamed;Alghamdi, Tariq Saeed;Alghamdi, Azla Aedh;Althagafi, Abeer Olayana;Aljassim, Fatima Jasim;Al-Ghamdi, Sameera Nasser. And the article was included in Industrial Crops and Products in 2022.SDS of cas: 105-87-3 This article mentions the following:

Sawtoothed grain beetles, Oryzaephilus surinamensis (Coleoptera: Silvanidae), cause severe damage to various stored products, reducing their quality and nutritional value. Several chem. pesticides have been introduced to control this pest and mitigate damage, but these pesticides also affect human health and the environment, enticing researchers to seek safer products and technol., such as plant-based products and nanotechnol. In this study, we compared the effectiveness of citronella essential oil and its nanoemulsion in controlling O. surinamensis adults. The citronella essential oil was obtained through hydrodistillation, and analyzed using gas chromatog. (GC) and GC/mass spectrometry MS based on the GC-MS anal., the predominant compounds were citronellal (46.95%), citronellol (9.49%), linalool (9.46%), β-caryophyllene (8.39%). The particles size of the prepared nanoemulsion was 57.98 nm. The lethal concentration that causes 50% mortality (LC50) in O. surinamensis adults for the pure essential oil and its nanoemulsion was 10, 15, 20, and 25 μL/L. The nanoemulsion was more effective against both females (LC50 = 20.3 μL/L) and males (LC50 = 15.7 μL/L) than the pure essential oil (LC50 = 40.02 and 52.5 μL/L, resp.). There was a significant difference in toxicity between the pure essential oil and its nanoemulsion. In addition, there were statistically significant differences (P < 0.05) between males and females when using citronella nanoemulsion only. In conclusion, citronella nanoemulsion is effective in controlling O. surinamensis and represents a promising alternative to chem. pesticides for protecting stored products. In the experiment, the researchers used many compounds, for example, (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3SDS of cas: 105-87-3).

(E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.SDS of cas: 105-87-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

High Affinity Central Benzodiazepine Receptor Ligands: Synthesis and Biological Evaluation of a Series of Phenyltriazolobenzotriazindione Derivatives was written by Primofiore, Giampaolo;Da Settimo, Federico;Taliani, Sabrina;Salerno, Silvia;Novellino, Ettore;Greco, Giovanni;Cosimelli, Barbara;Besnard, Francois;Costa, Barbara;Montali, Marina;Martini, Claudia. And the article was included in Journal of Medicinal Chemistry in 2005.Computed Properties of C10H11FO2 This article mentions the following:

A series of 2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1,5(6H)-diones (PTBTs), were prepared and tested at the central benzodiazepine receptor (BzR). The skeleton of these compounds was designed by formally combining the N-C:O moieties of the known BzR ligands, triazoloquinoxalines and triazinobenzimidazoles (ATBIs). Most of the PTBTs displayed submicromolar/nanomolar potency at the BzR. The 9-chloro derivatives were generally found to be more potent than their 9-unsubstituted counterparts. Compound (I) turned out to be the most potent of the PTBTs (K_i 2.8 nM). A subset of compounds when tested for their affinity on recombinant rat α1β2γ2, α2β2γ2, and α5β3γ2 GABA_A/Bz receptor subtypes, showed enhanced affinities for the α1β2γ2 isoform, with compounds I and (II) exhibiting the highest selectivity. Moreover, compounds I and II were found to display a full agonist efficacy profile at α1 and α2 receptor subtypes, and an antagonist efficacy at α5-containing receptors. In the experiment, the researchers used many compounds, for example, Ethyl 2-fluorophenylacetate (cas: 584-74-7Computed Properties of C10H11FO2).

Ethyl 2-fluorophenylacetate (cas: 584-74-7) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Computed Properties of C10H11FO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Highly Efficient and Chemoselective Zinc-Catalyzed Hydrosilylation of Esters under Mild Conditions was written by Kovalenko, Oleksandr O.;Adolfsson, Hans. And the article was included in Chemistry – A European Journal in 2015.Category: esters-buliding-blocks This article mentions the following:

A mild and highly efficient catalytic hydrosilylation protocol for room-temperature ester reductions has been developed using diethylzinc as the catalyst. The methodol. is operationally simple, displays high functional group tolerance and provides for a facile access to a broad range of different alcs. in excellent yields. In the experiment, the researchers used many compounds, for example, Methyl 2-thienylacetate (cas: 19432-68-9Category: esters-buliding-blocks).

Methyl 2-thienylacetate (cas: 19432-68-9) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Terpene volatiles mediates the chemical basis of blueberry aroma and consumer acceptability was written by Ferrao, Luis Felipe V.;Sater, Haley;Lyrene, Paul;Amadeu, Rodrigo R.;Sims, Charles A.;Tieman, Denise M.;Munoz, Patricio R.. And the article was included in Food Research International in 2022.Application of 105-87-3 This article mentions the following:

Flavor is among the most important traits valued by consumers of fresh fruits. Human perception of flavor occurs primarily through two main sensory inputs, taste and aroma. Through retronasal olfaction, volatile organic compounds (VOCs) emitted by the fruit are able to produce the sensation of aroma which when combined with gustatory inputs from the tongue together underly our perception of the thousands of flavors we experience throughout our lives. In blueberry, breeders have observed that some genotypes possess berries with unique ′floralâ€?and ′sweetâ€?flavor and aroma notes. The potential impact these characteristics might have on consumer acceptability is largely unknown and represents an opportunity to better understand how aroma attributes affect the perception of blueberry flavor. In this study, we dissected the main components of blueberry aroma and associated it with consumer predilections by pairing metabolomics with sensory anal. Our contribution in this study is four-fold: (i) first, we differentiated genotypes with floral and sweet aroma notes and confirmed that such characteristics are preferred by consumers; (ii) at the chem. level, we showed that a group of eight terpenoid volatiles (p-cymene, myrtenal, linalool, L-carvenol, geranyl acetone, geranyl acetate, D-limonene and β-myrcene) constitute the primary metabolic group associated with these aroma sensations; (iii) we demonstrated that aromatic genotypes can be classified using metabolomics; and finally, (iv) we combined pedigree and metabolomic information and showed the importance of metabolomic data for flavor-assisted selection. Our findings open new avenues to explore the phenomenon of flavor in blueberries and also allow us to present an emerging view about flavor and provide a detailed blueprint of how this targeted trait could be addressed in fruit and vegetable breeding. In the experiment, the researchers used many compounds, for example, (E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3Application of 105-87-3).

(E)-3,7-Dimethylocta-2,6-dien-1-yl acetate (cas: 105-87-3) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Application of 105-87-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Characterization of odour-active volatile compounds of acerola wine was written by Pino, J. A.;Quijano-Celis, C. E.. And the article was included in Acta Alimentaria in 2019.HPLC of Formula: 868-57-5 This article mentions the following:

The volatile compounds of acerola wine were isolated by headspace-solid phase microextraction (HS-SPME) and analyzed by gas chromatog.-flame ionization detector (GC-FID), gas chromatog.-mass spectrometry (GC-MS), and gas chromatog.-olfactometry (GC-O). The composition of acerola wine included 38 esters, 19 alcs., 16 acids, 8 terpenes, 5 aldehydes, 5 ketones, 3 furans, and 8 miscellaneous compounds The odor-active compounds were screened by application of the aroma extract dilution anal. and odor activity values. Nineteen odorants were considered as odor-active volatiles, from which Me 2-methylbutanoate and 2-ethylhexan-1-ol were the most odor-active compounds In the experiment, the researchers used many compounds, for example, Methyl2-methylbutyrate (cas: 868-57-5HPLC of Formula: 868-57-5).

Methyl2-methylbutyrate (cas: 868-57-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.HPLC of Formula: 868-57-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Model investigations on the mechanism of the osazone reaction. II was written by Dyong, Ingolf;Bertram, H. Peter. And the article was included in Chemische Berichte in 1973.Safety of Ethyl 2-hydroxy-3-phenylpropanoate This article mentions the following:

The aldehydes PhCHRCH(OH)CHO (I, R = OH) (II) and I (R = H) (III) behaved completely differently in reactions with hydrazine derivatives II yielded only the phenylhydrazone and, with difficulty, the derivative PhCOC(:NNPhMe)CH:NNPhMe. III reacted easily to give the derivatives PhCH2C(:NR)CH:NR [R = NHPh, NHC6H3(NO2)2-2,4, NPhMe]. The different reactivities were interpreted on the basis of a Weygand mechanism. In the experiment, the researchers used many compounds, for example, Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0Safety of Ethyl 2-hydroxy-3-phenylpropanoate).

Ethyl 2-hydroxy-3-phenylpropanoate (cas: 15399-05-0) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Safety of Ethyl 2-hydroxy-3-phenylpropanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics