Huang, Junjie et al. published their research in Zhongguo Yiyao Gongye Zazhi in 2016 | CAS: 41191-92-8

Ethyl 3-amino-4-methylbenzoate (cas: 41191-92-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Electric Literature of C10H13NO2

Synthesis of the related substances of Nilotinib hydrochloride was written by Huang, Junjie;Liao, Mingyi;Guo, Qi;You, Qidong. And the article was included in Zhongguo Yiyao Gongye Zazhi in 2016.Electric Literature of C10H13NO2 This article mentions the following:

To strengthen the quality control of Nilotinib hydrochloride, five related substances of Nilotinib were synthesized based on its synthetic process. These substances, including 3-[4-(pyridin-3-yl) pyrimidin-2-ylamino]-4-methylbenzoic acid (A), 3-[4-(pyridin-3-yl) pyrimidin-2-ylamino]-N-[3-(4-ethyl-1H-imidazol-1-yl)-5-(trifluoromethyl) phenyl]-4-methylbenzamide (B), 3-[4-(pyridin-3-yl) pyrimidin-2-ylamino]-N-[3-(trifluoromethyl)-5-(1H-imidazol-1-yl) phenyl]-4-methylbenzamide (C), 3-[4-(pyridin-3-yl) pyrimidin-2-ylamino]-N-[3-(trifluoromethyl)-5-(2,4-dimethyl-1H-imidazol-1-yl) phenyl]-4-methylbenzamide (D), 3-[4-(pyridin-3-yl) pyrimidin-2-ylamino]-N-[3-(trifluoromethyl)-5-(5-methyl-1H-imidazol-1-yl) phenyl]-4-methylbenzamide (E), were synthesized and their structures were confirmed by MS and 1H NMR. In the experiment, the researchers used many compounds, for example, Ethyl 3-amino-4-methylbenzoate (cas: 41191-92-8Electric Literature of C10H13NO2).

Ethyl 3-amino-4-methylbenzoate (cas: 41191-92-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Electric Literature of C10H13NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics