Category: esters-buliding-blocks

Jebara, Amel published the artcilePhthalates and non-phthalate plasticizers in Tunisian marine samples: Occurrence, spatial distribution and seasonal variation, Name: Dimethyl adipate, the publication is Marine Pollution Bulletin (2021), 111967, database is CAplus and MEDLINE.

Seawater, sediment, seagrass and fish from several sites along the Tunisian coast were monitored for several phthalate esters (PAEs) and non-phthalate plasticizers (NPPs) during 2018-2019. In water and sediment, NPPs were higher than PAEs, being di(2-ethylhexyl) phthalate (DEHP, 0.0717 and 4.59μg/g), and di(2-ethylhexyl) terephthalate (DEHT, 0.634 and 2.42μg/g) most abundant. As expected, sediments acted as a sink for plasticizers, thus revealing a stronger contamination than water. Seagrass was less contaminated than fish, being DEHP (0.726 and 1.77μg/g) and DEHT (9.19 and 23.2μg/g) predominant. Biota poorly concductivity/accumulated plasticizers from water and sediment depending on the logKoct/wat and water solubility of single congeners. The spatial distribution of plasticizers was affected by the proximity to anthropogenic sources and the rate of coastal currents; whereas their seasonal variation may be related to the length of time of touristic/industrial inputs and factors such as rainfall and urban stormwater runoff.

Marine Pollution Bulletin published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C8H14O4, Name: Dimethyl adipate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Furber, Mark published the artcileDiscovery and evolution of phenoxypiperidine hydroxyamide dual CCR3/H₁ antagonists. Part I, Safety of (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, the publication is Bioorganic & Medicinal Chemistry Letters (2012), 22(24), 7702-7706, database is CAplus and MEDLINE.

The discovery of potent small mol. dual antagonists of the human CCR3 and H₁ receptors is described for the treatment of allergic diseases, for example, asthma and allergic rhinitis. Optimizing in vitro potency and metabolic stability, starting from a CCR1 lead compound, led to compound 20 with potent dual CCR3/H₁ activity and in vitro metabolic stability.

Bioorganic & Medicinal Chemistry Letters published new progress about 115314-17-5. 115314-17-5 belongs to esters-buliding-blocks, auxiliary class Epoxides,Chiral,Nitro Compound,Sulfonate,Benzene, name is (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, and the molecular formula is C9H9NO6S, Safety of (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Alexeev, S. G. published the artcileCorrelation of fire hazard characteristics with chemical structure. X. esters (part 2), SDS of cas: 5340-78-3, the publication is Pozharovzryvobezopasnost (2013), 22(5), 9-19, database is CAplus.

The correlation of chem. structure and fire-dangerous properties is studied among aliphatic esters of isostructure. The carbon rule well works for these compounds It is allowed to predict their physicochem. and fire-dangerous indexes. Travel of the ester group along a hydrocarbon chain practically does not lead to change of the physicochem. and fire-dangerous properties of esters. The empirical equations of calculation are offered for critical temperature (T_c (K) = -0.46(N_c)² + 27.03(N_c) + 430.1), b.p. (TB (K) = – 0.379(N_c)² + 26.448(N_c) + 254), flash point (FP (K) = -0.3107(N_c)² + 17.475(N_c) + 206.4; FP (°C) = -0.627TB (°C) – 50.4); fire (ignition) temperature (FT (K) = 13.65(N_c) + 227.6), low and upper temperature explosive limits (LTEL (K) = 13.54(N_c) + 215, UTEL = 16(N_c) + 236.2), low and upper explosive limits (LTEL (%) = 10.472(N_c)^-1.1297, UEL (%) = 1.16 + 43.051/(N_c)), combustion heat (Q (kJ/mol) = 606.2(N_c) – 321.6) and critical pressure (P_c (atm) = -10.486 + 99.243/(N_c)^0.5) from the conventional hydrocarbon chain (N_c) in an ester mol.

Pozharovzryvobezopasnost published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C8H16O2, SDS of cas: 5340-78-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

El-Hefnawy, Mohamed E. published the artcileEndogenous bioethanol production by solid-state prefermentation for enhanced crude bio-oil recovery through integrated hydrothermal liquefaction of seaweeds, Synthetic Route of 30414-53-0, the publication is Journal of Cleaner Production (2022), 131811, database is CAplus.

The present study evaluated the action of endogenous bioethanol produced during solid-state fermentation of Ulva spp. on subsequent hydrothermal liquefaction (HTL). HTL of raw biomass (RB) was compared with HTL of the fermented biomass after bioethanol separation (F-Aqua) and HTL of the whole fermentation broth containing the bioethanol (F-Eth). Optimization of fermentation conditions increased the ethanol yield efficiency (Y_eff) and specific ethanol yield (SEY) from 23.55% and 0.120 g g^-1 sugar consumed to 43.97% and 0.224 g g^-1 sugar consumed, resp. TGA and FTIR anal. confirmed noticeable changes in the thermal profile and functional groups of the fermented residue with increased volatiles and lower ash content. Among different HTL treatments, F-Eth showed the highest bio-oil yield of 24.96% at 250°C, which was 37.7% and 39.0% higher than that of RB and F-Aqua, resp. In addition, hydrocarbons and esters in the bio-oil represented the dominant compounds in F-Aqua and F-Eth, altogether 28.28% and 68.58%, resp., compared to 17.96% in RB. Economic anal. for a proposed 100 ton year^-1 plant confirmed that HTL of the whole fermentation broth containing endogenous bioethanol enhanced the gross energy output to 8.152 GJ ton^-1, which represented 4.2-time, 51.1%, and 23.3% higher than individual bioethanol production, individual bio-oil production, and sequential bioethanol/bio-oil recovery, with the highest net annual profit of 29553 US$ compared to 23391 US$ for the sequential production

Journal of Cleaner Production published new progress about 30414-53-0. 30414-53-0 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ketone,Ester, name is Methyl 3-oxovalerate, and the molecular formula is C6H10O3, Synthetic Route of 30414-53-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Tawfeek, Mohamed E. published the artcilePotential insecticidal activity of four essential oils against the rice weevil, Sitophilus oryzae (L.) (coleoptera: curculionidae), COA of Formula: C8H14O4, the publication is BioResources (2021), 16(4), 7767-7783, database is CAplus.

Oils extracted from Cymbopogon citratus, Lantana camara, Artemisia camphorata, and Imperata cylindrica plants were used as potential insecticides against the rice weevil, Sitophilus oryzae (L.) (Coleoptera: Curculionidae). The phytochem. composition of the isolated oils was identified by gas chromatograph-mass spectrometry (GC-MS). Oil contact toxicities were evaluated against the adults of S. oryzae. The activities of acetylcholinesterase (AChE), alk. phosphatase (ALP), and transaminases enzymes (AST) were measured. L. camara oil (LC₅₀ = 9.81 mg/cm²) demonstrated the highest effect, followed by C. citratus oil (LC₅₀ = 10.89 mg/cm²), A. camphorata EO (LC₅₀ = 16.12 mg/cm²), and I. cylindrica oil (LC₅₀ = 36.85 mg/cm²) against the adults of S. oryzae. The inhibition percentages of AChE were 38.8, 41.7, 35.0, and 27.2%; ALP were 42.4, 49.3, 28.1, and 18.7%; AST were 33.9, 38.7, 20.8, and 11.8%; and ALT were 22.7, 30.5, 14.6, and 9.6% after treated S. oryzae with oils from C. citratus, L. camara, A. camphorata and I. cylindrica, resp. The highest abundant compounds in C. citratus were geranial (25.95%), nerylacetal (8.85%), and neral (8.45%), in L. camara were caryophyllene (12.2%), and 3-elemene (8.89%), in A. camphorata were germacrene D-4-ol (20.83%), and borneol (19.47%), and in I. cylindrica were 5-phenylundecane (10.68%), and 6-phenyldodecane (8.70%).

BioResources published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C9H13NO2, COA of Formula: C8H14O4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

El-Essawy, Farag A. published the artcileSynthesis and Anti-HIV Activity of Poly-Heterocyclic Compounds Containing Quinoline Moiety, Application of 3-Acetyldihydrofuran-2(3H)-one, the publication is Russian Journal of General Chemistry (2022), 92(6), 1129-1136, database is CAplus.

A novel series of poly-heterocyclic compounds containing quinoline as antiviral agents against HIV was designed and synthesized. Structures of these novel derivatives was confirmed by IR, NMR, and EI-MS spectra. Most of the products was tested for their HIV inhibitory activity and characterized by high to moderate activity.

Russian Journal of General Chemistry published new progress about 517-23-7. 517-23-7 belongs to esters-buliding-blocks, auxiliary class Tetrahydrofuran,Ketone,Ester, name is 3-Acetyldihydrofuran-2(3H)-one, and the molecular formula is C6H8O3, Application of 3-Acetyldihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Beltifa, Asma published the artcileIdentification and quantification of plasticizers, bisphenol, and environmental toxic mineral elements residues in medicines from Tunisian markets, Recommanded Product: Dimethyl adipate, the publication is Environmental Science and Pollution Research (2021), 28(36), 50462-50470, database is CAplus and MEDLINE.

In this study, 18 plasticizer (phthalates, adipates, sebacates, and others) residues in sixteen medicines available in Tunisian pharmaceutical markets are evaluated by MSPD combined with GC-MS. In parallel, in this research, UPLC-MS/MS technique was performed to detect bisphenol A, and cadmium, lead, chromium, cobalt, nickel, mercury, selenium, and arsenic levels were determined by ICP-MS. The maximum daily ingested mass of mineral elements was calculated and compared with permissible daily exposure limits published by USP NF 2013. Our results demonstrated that the 50% of drugs contained similar concentrations of di-Et adipate. Di-iso-Bu phthalate was found in a single sample with a high concentration (1.07 mgkg-1). Di-methyladipate was also present in only one sample. Di-Et phthalate was detected in three medicines: the highest concentration (17.03 mgkg-1) was found in capsules. The other plasticizers and bisphenol A levels were below the limits of quantification in the all samples. All tested products were safe for use, except two clay-originated products. Concentrations and the maximum daily ingested mass of lead and arsenic were higher than recommended limits. The use of these medicines should require more attention taking into account the serious hazards of heavy metals to human health.

Environmental Science and Pollution Research published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C8H14O4, Recommanded Product: Dimethyl adipate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Sheta, Ahmed M. published the artcileSelective Electrosynthetic Hydrocarboxylation of α,β-Unsaturated Esters with Carbon Dioxide, Computed Properties of 103-26-4, the publication is Angewandte Chemie, International Edition (2021), 60(40), 21832-21837, database is CAplus and MEDLINE.

An electrochem. approach that is able to hydrocarboxylate α,β-unsaturated alkenes with excellent regioselectivity and ability to carboxylate hindered substrates to afford α-quaternary center carboxylic acids was reported. The process required no chromatog. and products were purified by simple crystallization from reaction mixture after work-up.

Angewandte Chemie, International Edition published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C13H10O2, Computed Properties of 103-26-4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Al-Hiari, Yusuf M. published the artcileSynthesis and antibacterial properties of new 8-nitrofluoroquinolone derivatives, Related Products of esters-buliding-blocks, the publication is Molecules (2007), 12(6), 1240-1258, database is CAplus and MEDLINE.

A series of new 8-nitrofluoroquinolone derivatives has been prepared to study their antibacterial properties. The work initially involved large scale preparation of the synthon 7-chloro-1-cyclopropyl-6-fluoro-8-nitro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid followed by introduction of substituted primary amine appendages at the C-7 position to give amino derivatives, e.g., I (R = H, Me, Cl), using anilines, 2-aminopyridines, and other primary amines. This nucleophilic aromatic substitution step was a very simple procedure since the 8-nitro group of the above synthon facilitated the addition of weak nucleophiles at C-7. The prepared targets and the intermediates have shown interesting antibacterial activity against gram pos. and/or gram neg. strains. In particular, the p-toluidine, p-chloroaniline and aniline derivatives showed good activity against S. aureus with MIC range ≈ 2-5 μg/mL. In conclusion, more lipophilic groups seem to enhance activity against gram pos. strains.

Molecules published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C7H13NO2, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics