On October 22, 1997, Bessard, Ives; Stucky, Gerhard published a patent.Product Details of 121129-31-5 The title of the patent was Process for the preparation of substituted pyrimidines. And the patent contained the following:
Pyrimidines I [R1 = OCHR4COR5, 2-oxo-3-tetrahydrofuryl, 2-oxo-3-tetrahydropyranyl, (un)substituted Ph, pyridyl; R2, R3 = H, alkyl, alkoxy, (un)substituted NH2; R4 = H, alkyl, aryl, aralkyl, CO2H, acyl, alkoxycarbonyl; R5 = OH, alkoxy, aryloxy, alkyl] were prepared by treating I [R1 = halogen] with HOR1 in presence of a sulfinate in a one- or two-step reaction. Thus, 2-chloro-4,6-dimethoxypyrimidine was treated with Me3CCH(OH)CO2Me and MeSO2Na to give 82.7% I [R1 = OCH(CMe3)CO2Me, R2, R3 = OMe]. The experimental process involved the reaction of Methyl 2-hydroxy-3,3-dimethylbutanoate(cas: 121129-31-5).Product Details of 121129-31-5
The Article related to alkoxypyrimidine preparation, halopyrimidine alkoxylation sulfinate, pyrimidine halo alkoxylation sulfinate, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Product Details of 121129-31-5
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