Bhat, Subrahmanya Ishwar; Das, U. K.; Trivedi, Darshak R. published an article in 2015, the title of the article was An Efficient Three-component, One-pot Synthesis of Quinazolines under Solvent-free and Catalyst-free Condition.Computed Properties of 707-07-3 And the article contains the following content:
An efficient green protocol for the synthesis of quinazolines in the absence of solvent and catalyst was developed. 2,4-disubstituted quinazolines were synthesized from three-component one-pot reactions of 2-aminoaryl ketones, orthoesters, and ammonium acetate. The present method had advantages of operational simplicity, substrate generality, clean reaction, high yields (76-94%), and moderate reaction time. The plausible mechanism of the reaction was proposed based on the spectral characterization and single crystal X-ray anal. of isolated intermediate. The experimental process involved the reaction of (Trimethoxymethyl)benzene(cas: 707-07-3).Computed Properties of 707-07-3
The Article related to aminoaryl ketone orthoester ammonium acetate three component reaction, quinazoline preparation green chem, Heterocyclic Compounds (More Than One Hetero Atom): Pyrimidines and Quinazolines and other aspects.Computed Properties of 707-07-3
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