Novel bis-cyclic guanidines as potent membrane-active antibacterial agents with therapeutic potential was written by Teng, Peng;Nimmagadda, Alekhya;Su, Ma;Hong, Yuzhu;Shen, Ning;Li, Chunpu;Tsai, Ling-Yu;Cao, Jessica;Li, Qi;Cai, Jianfeng. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2017.SDS of cas: 87694-53-9 This article mentions the following:
We designed a class of small dimeric cyclic guanidine derivatives which display potent antibacterial activity against both multidrug-resistant Gram-neg. and Gram-pos. bacteria. They could compromise bacterial membranes without developing resistance, inhibit biofilms formed by E. coli, and exhibit excellent in vivo activity in the MRSA-infected thigh burden mouse model. In the experiment, the researchers used many compounds, for example, (S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9SDS of cas: 87694-53-9).
(S)-tert-Butyl (1-(methoxy(methyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate (cas: 87694-53-9) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.SDS of cas: 87694-53-9
Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics