Month: December 2022

Isabel Cadena-Aizaga, M. published the artcileOccurrence and bioconcentration of organic UV filters in primary marine consumers, SDS of cas: 71617-10-2, the main research area is organic UV filter bioconcentration marine environmental pollution.

Organic UV filters are added in different products to absorb UV radiation, whose use has been voiced due to increasing concerning about skin damage. Given their extensive production, these compounds are continuously released to the aquatic environment, which makes them an important family of emerging pollutants. Their presence in the marine environment poses a hazard to the living organisms exposed to them. Primary marine consumers can be recognized as sentinels of pollution in marine environments. In this study, the occurrence of eight widely used organic UV filters was analyzed in five different primary marine consumers from three beaches on the Gran Canaria Island (Spain) collected for 4 mo. For that, a new method, based on microwave-assisted extraction and ultrahigh-performance liquid chromatog. coupled to mass spectrometry in tandem, was optimized and validate. The developed method presented detection limits between 0.7 ng·g-1 dry weight (dw) and 7.1 ng·g-1 dw and intraday and interday precision with ranges from 0.2% to 9.9% and from 1.9% to 12.4%, resp. The method was applied to 20 samples comprising five different types of organisms. All the analyzed samples revealed the presence of organic UV filters, in all samples at least one analyte was determined The highest detection frequency corresponded to Bu methoxydibenzoylmethane (BMDBM) (55%), while octocrylene (OC) was found at the highest concentration (1,735 ng·g-1 dw) in the sea hare Aplysia dactylomela. At the same time, a preliminary bioconcentration and biomagnification assessment was made for the UV filters found in the studied marine organisms. Bioconcentration factors (Log values) over 3.7 were obtained in some cases, which suggests possible bioaccumulation. 4-methylbenzylidene camphor (4MBC) and drometrizole trisiloxane (DTS) obtained a biomagnification factor over 1, which implies potential biomagnification for these compounds

Microchemical Journal published new progress about Aplysia dactylomela. 71617-10-2 belongs to class esters-buliding-blocks, name is Isopentyl 3-(4-methoxyphenyl)acrylate, and the molecular formula is C15H20O3, SDS of cas: 71617-10-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hosseinipour, Morteza published the artcileThe antioxidant effects of hydroalcoholic extract of Ashrasi date palm on sperm parameters and DNA fragmentation in diabetic rats, Application of Methyl decanoate, the main research area is ADP sperm DNA fragmentation hydroalcoholic extract antioxidant diabetics; Ashrasi date palm; antioxidant; diabetes; oxidative stress.

Diabetes-induced oxidative stress can have adverse effects on sperm and its DNA integrity. The Ashrasi date palm (ADP) has potent antioxidant properties. The aim of this study was to evaluate the antioxidant effect of ADP hydroalcoholic extract on sperm parameters and sperm DNA fragmentation in diabetic rats. Forty male rats were randomly divided into five groups (n = 7): 1, control; 2, diabetic; 3-5, diabetic + ADP (30, 90 and 270 mg/kg for groups 3, 4 and 5, resp.). After preparation of ADP extract and its phytochem. screening, it was administered orally to rats, once a day for 5 wk. At the end of the study, sperm parameters and sperm DNA fragmentation in all groups were investigated. At doses of 90 and 270 mg/kg, ADP extract significantly increased the sperm viability compared to diabetic group 2 (p = 0.04 and p = 0.03, resp.) and resulted in a significant decrease in immotile sperm (p = 0.002 and p = 0.006, resp.). At a dose of 270 mg/kg, a considerable enhancement of forward sperm motility was observed (p = 0.04) and there was a significant decrease in sperm DNA fragmentation (p = 0.04). The findings of the present study show for the first time that the hydroalcoholic extract of ADP has protective and antioxidant effects against diabetes-induced oxidative stress and can improve sperm parameters and protect sperm DNA integrity.

Animal Models and Experimental Medicine published new progress about Antidiabetic agents. 110-42-9 belongs to class esters-buliding-blocks, name is Methyl decanoate, and the molecular formula is C11H22O2, Application of Methyl decanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ragab, N. A. published the artcileChemical characterization of Melilotus messanensis (L.) all.: Antioxidant, antidiabetic and antimutagenic effects in alloxan induced diabetic rats, Quality Control of 929-77-1, the main research area is Melilotus messanensis antioxidant antidiabetic antimutagenic effect alloxan diabetes.

Melilotus Mill.Species have been used in various traditional medical systems. Recent studies suggested that Melilotus species may have pharmacol. significance against diabetes mellitus; however, none of them associated their bioactive virtues with chem. identity. The current study aims to reveal the chem. profile of the Melilotus messanensis (L.) All. extracts and their biol. evaluation. Petroleum ether extract (PEE) was analyzed by GC/MS assay which revealed the characterization of thirty two metabolites. Moreover, the chromatog. investigation of defatted aqueous methanol extract (DAME) led to the isolation of fifteen phenolics, from which, thirteen compounds have been isolated for the first time from M. messanensis. Also, LC-ESI-MS chem. profiling managed to detect addnl. sixteen metabolites. The aqueous methanol extract (AME), PEE and DAME were subjected to antioxidant, antidiabetic and antimutagenic assays. Diabetes mellitus was induced using a single dose of Alloxan (150 mg/kg b. weight) and exhibited as DM_rats model. Potential activities of AME, PEE and DAME (100 mg/kg b. weight i. p.) in treating DM_rats were investigated and exhibited a significant antioxidant activity with % of change 10, 11 and 13, resp., compared to vitamin E (9%) and neg. control DM_rats (45%). Addnl., they showed anti-diabetic activities (blood glucose levels) after four weeks with % change 53, 52 and 60, resp., in comparison with metformin (5 mg/kg b. weight i. g.) group (69%). Also, all extracts showed high inhibitory indexes of bone marrow and sperm cells aberrations in DM_rats. The prominent antihyperglycemic and antigenotoxic activities could be attributed to the abundant identified flavonoids and fatty acids.

Biocatalysis and Agricultural Biotechnology published new progress about Antidiabetic agents. 929-77-1 belongs to class esters-buliding-blocks, name is Methyl docosanoate, and the molecular formula is C23H46O2, Quality Control of 929-77-1.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Joshi, Nikita published the artcileNutritional properties of pumpkin seeds: emerging seed for a therapeutic benefits, Recommanded Product: Methyl docosanoate, the main research area is therapeutic benefit pumpkin seeds emerging seed nutritional property.

In recent time, seeds and nuts of plants got tremendous attention due to its various health benefits. Pumpkin seeds are thrown out by most of the industries, as agricultural waste. Pumpkin seeds are commonly known as “”pepitas””. Pumpkin seeds are loaded with variety of nutrients and particularly they are rich in Proteins, Vitamins and Minerals.However, assuming that being traditional food, people are not aware about the nutritional benefits of that and still it is unexploited. The objective of this study is to evaluate the proximate composition, fatty acid profile, Antioxidant activity and Micronutrients (Vitamins and Minerals) of pumpkin seeds (Cucurbita Moschata). Proximate composition and mineral composition of pumpkin seeds was carried by using AOAC methods, Fatty acid profile by Gas Chromatog., Vitamins by HPLC methods and FRAP method was used for the assessment of antioxidant activity. As per the results obtained, pumpkin seeds are rich in protein, Selenium, Zinc and Unsaturated fatty acids therefore, pumpkin seeds can be used for a therapeutic management of Diabetes, Hyperlipidemia, Cancer prevention and enhancement of immunity. Therefore, modification of these waste agricultural product into valuable element will be a huge step towards food sustainability.

World Journal of Pharmaceutical Research published new progress about Antidiabetic agents. 929-77-1 belongs to class esters-buliding-blocks, name is Methyl docosanoate, and the molecular formula is C23H46O2, Recommanded Product: Methyl docosanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ahmad, Imtiaz published the artcileGC-MS profiling, phytochemical and biological investigation of aerial parts of Leucophyllum frutescens (Berl.) I.M. Johnst (Cenizo), Application In Synthesis of 929-77-1, the main research area is Leucophyllum type II diabetes phytochem antidiabetic antimicrobial erythrocyte hemolysis.

Leucophyllum frutescens (Berl.) I. M. Johnst has been used as a crude drug for treating various respiratory ailments, dysentery, cataract and liver disorders in the folk medicine systems by the inhabitants of America and Mexico. The Phytochem. and biol. investigation was established by spectrophotometrically and chem. profiling was performed by GC-MS anal. The chem. profiling by GC-MS anal. revealed that HELE majorly contains 9-octadecenoic acid (Z)-, Me ester, pentadecanoic acid, 14-methyl-, Me ester, 2,6-bis(3,4-methylenedioxyphenyl)-3,7-dioxabicyclooctane, (+)-sesamin, 9,12-octadecadienoic acid, Me ester, 9,12,15-octadecatrienoic acid, Et ester, (Z,Z,Z)-, n-hexadecanoic acid, hexadecanoic acid, Et ester, phytol, Me stearate, cyclohexanone, 1H,3H-Furo[3,4-c]furan, 1,4-bis(3,4-dimethoxy phenyl)tetrahydro-, [1R-(1.alpha.,3a.alpha.,4.alpha.,6a.alpha.)]-, and squalene. Strong inhibition of α-glucosidase and urease enzymes was observed by HELE (IC50 0.3321 mg.mL-1) and CHLE (IC50 4.711 mg.mL-1) extracts, resp. Phytochem. quantification revealed high TPC by BULE (189.369±1.393 mg GA.Eq.gm-1 DE ± S.D) and high TFC by CHLE (232.458±1.589 mg Qu.Eq.gm-1 DE ± S.D). CHLE presented with highest antioxidant content equivalent to Trolox, by five different spectrophotometric methods such as TAA, DPPH, TEAC, FRAP, and CUPRAC. The study concludes that L. frutescens possesses significant antioxidant, antidiabetic and cytotoxic activities indicating that L. frutescens as a potential candidate for discovery of novel phytochem. products and industrial applications.

South African Journal of Botany published new progress about Antidiabetic agents. 929-77-1 belongs to class esters-buliding-blocks, name is Methyl docosanoate, and the molecular formula is C23H46O2, Application In Synthesis of 929-77-1.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Le, Xiaoxia published the artcileFluorescent Organohydrogel with Thermal-Induced Color Change for Anti-counterfeiting, Recommanded Product: Dodecyl 2-methylacrylate, the main research area is acrylic fluorescent hydrogel color change anticounterfeiting.

Smart fluorescent patterns enable dynamic color variation under external stimuli, showing a much higher security level in the field of anti-counterfeiting. However, there is still lacking of a simple and convenient way to achieve dynamic fluorescence changes. Herein, a fluorescent organohydrogel made up of a poly(N,N-dimethylacrylamide-co-isopropylacrylamide) (p(DMA-NIPAM)) hydrogel network and a poly(lauryl methacrylate) (PLMA) organogel network was fabricated via a two-step interpenetrating technique. The former network bears naphthalimide moieties (DEAN, green fluorescent monomer) and the later contains 6-acrylamidopicolinic acid (6APA, fluorescent ligand), leading to emitting green fluorescence. When Eu3+ was introduced and coordinated with 6APA, the organohydrogel displays red fluorescence, which can further emit yellow after applying thermal stimulus. Furthermore, by adjusting the proportion of comonomers, various organohydrogels can be obtained, which can be programmed and act as an effective platform for the encryption and decryption of secret information.

Chinese Journal of Chemistry published new progress about Anti-counterfeiting. 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, Recommanded Product: Dodecyl 2-methylacrylate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Forouhandeh, Haleh published the artcileEvaluation of the cytotoxic activity of Anthriscus nemorosa on breast cancer cells, Related Products of esters-buliding-blocks, the main research area is Anthriscus nemorosa cytotoxicity breast cancer cell.

The present study concerns the cytotoxic activity of A. nemorosa different extracts on breast cancer cells (MCF-7) and normal cell lines (HFFF). Different extracts of aerial parts of A. nemorosa were prepared using Soxhlet apparatus The cytotoxicity of samples was assessed by MTT assay on breast cancer cells (MCF-7) and noncancerous cells (HFFF) with different concentrations of extracts in 24 and 48 h. The most potent extract was fractioned and cytotoxic activity of fractions was considered, As well. A flow cytometry (annexin V/PI) assay has been used for detecting the mechanism of cell death in sample treated cell lines. Moreover, for clarifying volatile components of n-Hexane extract and its 80% and 100% VLC fractions were subjected to GC-MS apparatus Results indicated that n-Hexane extract and its 80% and 100% VLC fractions exhibited a significant (P < 0.001) inhibitory effect on the growth of the MCF-7 cell line compared to the control group. Meanwhile, flow cytometry anal. revealed that potent extract caused cell death through necrosis and 80% and 100% fractions showed different mechanisms (such as autophagy). The major compounds, which maybe were in charge of showing cytotoxic activity were non-terpenoids. This study provides the evidence that in vitro cytotoxic activity of n-Hexane extract and 80% and 100% VLC fractions of A. nemorosa inhibited the proliferation of breast cancer cells (MCF7) via a different mechanism. Journal of Contemporary Medical Sciences published new progress about Anthriscus nemorosa. 929-77-1 belongs to class esters-buliding-blocks, name is Methyl docosanoate, and the molecular formula is C23H46O2, Related Products of esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Molnar, Bela Peter published the artcileDevelopment of a Female-Targeted Lure for the Box Tree Moth Cydalima perspectalis (Lepidoptera: Crambidae): a Preliminary Report, Related Products of esters-buliding-blocks, the main research area is Cydalima bisexual lure flower volatile; Bisexual lure; Flower volatiles; Invasive pest; Pheromone; Trapping.

In this study, we aimed to develop a “”bisexual”” lure to attract both female and male moths. Based on a previous screening bioassay we tested Me salicylate, phenylacetaldehyde and eugenol as potential attractants in different combinations. The trapping results showed that both binary and ternary blends attracted male and female moths. Catches with these blends were comparable to catches with the synthetic pheromone. Subsequently we carried out single sensillum recordings, which proved the peripheral detection of the above-mentioned compounds on male and female antennae. To identify synergistic flower volatiles, which can be also attractive and can increase the trap capture, we collected flower headspace volatiles from 12 different flowering plant species. Several components of the floral scents evoked good responses from antennae of both females and males in gas chromatog.-electroantennog. detection. The most active components were tentatively identified by gas chromatog. coupled mass spectrometry as benzaldehyde, cis-ss-ocimene, (±)-linalool and phenethyl alc. These selected compounds in combination did not increase significantly the trap capture compared to the Me salicylate- phenyacetaldehyde blend. Based on these results we discovered the first attractive blend, which was able to attract both adult male and female C. perspectalis in field conditions.

Journal of Chemical Ecology published new progress about Antennas, apparatus. 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Related Products of esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lim, Sooho published the artcileAbdominal contact of fluvalinate induces olfactory deficit in Apis mellifera, Recommanded Product: Benzyl acetate, the main research area is Apis abdomen fluvalinate olfactory cognition; Fluvalinate; Olfactory deficit; Olfactory modulation; Short neuropeptide F; sNPF signaling.

The τ-Fluvalinate (fluvalinate) is a highly selective pyrethroid insecticide compound used for controlling ectoparasitic mites that cause major damages in honey bee colonies. Although honey bees have resistance and low toxicity to this xenobiotic chem., little is known about the effects of this chem. on sensory modulation and behaviors in honey bees. Here we addressed the effect on olfactory cognition at the behavioral, mol., and neurophysiol. levels. First, we found that topical application of fluvalinate to honeybee abdomen elicited somewhat severe toxicity to honey bees. Furthermore, honeybees treated with sublethal doses of fluvalinate showed a significant decrease in olfactory responses. At the mol. level, there was no change in gene expression levels of odorant receptor co-receptor (Orco), which is important for elec. conductivity induced by odorant binding in insects. Rather, small neuropeptide F (sNPF) signaling pathway was involved in olfactory fluctuation after treatment of fluvalinate. This indicates that olfactory deficits by abdominal contact of fluvalinate may stem from various internal mol. pathways in honey bees.

Pesticide Biochemistry and Physiology published new progress about Antennas, apparatus. 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Recommanded Product: Benzyl acetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics