Month: December 2022

Lu, Xueyan published the artcileComparative metabolomics of two saline-alkali tolerant plants Suaeda glauca and Puccinellia tenuiflora based on GC-MS platform, Quality Control of 111-11-5, the main research area is Suaeda Puccinellia comparative metabolome; Salt-alkali stress; agroforestry; physiological response; primary metabolites.

Suaeda glauca and Puccinellia tenuiflora are two important saline-alkali tolerant plants that can improve the soil properties. For exploring the different tolerance mechanisms between them, GC-MS-based metabolomics was used to comprehensively evaluate the primary metabolites differences, a total of 51 different metabolites were present in different quantities. The identified compounds were mainly 11 sugars, 7 amino acids, 5 alcs. and 18 organic acids; they play an important role in responding to the saline-alkali stress and distinguish between S. glauca and P. tenuiflora. All identified metabolites classes showed similar trend to largely accumulate in P. tenuiflora roots and S. glauca shoots, this reveals that the two plants used different physiol. strategies to cope with saline-alkali stress.

Natural Product Research published new progress about Metabolomics. 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, Quality Control of 111-11-5.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Liu, Xin published the artcileEco-friendly quantum dots for liquid luminescent solar concentrators, Category: esters-buliding-blocks, the main research area is ecofriendly quantum dot liquid luminescent solar concentrator.

Luminescent solar concentrators (LSCs) are a promising solution to reduce the cost of integrated photovoltaic (PV) cells. Colloidal quantum dots (QDs) were excellent candidates as a new type of absorber/emitter in LSCs, due to their size-tunable absorption and emission, high photoluminescence quantum yield (PLQY) and structure-engineered large Stokes shift. However, to date, the majority of QD-based LSCs employ QDs containing heavy-metal (e.g. Cd or Pb) elements, which limits the potential commercialization of LSCs. Herein, we propose the synthesis of green transition metal ion-doped semiconductor QDs such as Cu-doped ZnInSe QDs and their use as luminophores in LSCs. By tailoring the amount of Cu doping, it was possible to tune the photoluminescent (PL) emissions over the whole visible spectral window and simultaneously enlarge the Stokes shift, reaching a PLQY of 63%. Furthermore, a comparative study between polymer and liquid solar concentrators showed that, under optimal conditions, it is possible to obtain a green, heavy metal free liquid QD-based LSC with a high optical efficiency of over 3.5%. This result is more than two times higher than that of a polymer LSC (ηopt = 1.75%, G = 10), which could be ascribed to the reduced reabsorption losses and avoided energy loss by surface and internal defects resulting from polymerization The waveguides for liquid LSCs could be recycled for tuning the concentrations and changing various luminophores which makes the liquid LSCs cost-effective and environmentally friendly. The success of eco-friendly Cu doped Zn-In-Se QDs for liquid LSCs provides a platform of more efficient and environmentally friendly solar energy harvest systems. In addition, the comparative study between liquid and polymer waveguides provides an opportunity to optimize LSC performance.

Journal of Materials Chemistry A: Materials for Energy and Sustainability published new progress about Luminescence. 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hommes, Arne published the artcileAerobic oxidation of benzyl alcohol in a slug flow microreactor: Influence of liquid film wetting on mass transfer, Quality Control of 140-11-4, the main research area is oxidation benzyl alc slug microreactor film wetting mass transfer.

Homogeneous Co/Mn/Br catalyzed aerobic oxidation of benzyl alc. in acetic acid to benzaldehyde was performed in polytetrafluoroethylene microreactors operated under slug flow at temperatures up to 150° and pressures up to 5 bar. Depending on the bubble velocity and length, a wetted or dewetted slug flow was observed, characterized typically by a complete or partially wetting liquid film around the bubble body. The latter flow suffered from a limited interfacial area for mass transfer. Experiments at temperatures up to ∼90° were under kinetic control given no product yield difference under wetted and dewetted slug flows and were used to establish a simplified kinetic expression (first order in benzyl alc. and zero order in oxygen). This allows to develop a mass transfer model combined with an instantaneous reaction regime that well described the exptl. results at higher temperatures where mass transfer was limiting in the dewetted slug flow.

AIChE Journal published new progress about Liquid films. 140-11-4 belongs to class esters-buliding-blocks, name is Benzyl acetate, and the molecular formula is C9H10O2, Quality Control of 140-11-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chen, Zhiyong published the artcileStudy on the formation of ethyl levulinate from wheat straw based on a model compound, COA of Formula: C7H12O3, the main research area is ethyl levulinate wheat straw glucose microcrystalline cellulose.

Glucose and microcrystalline cellulose were selected as model compounds to investigate the formation of Et levulinate (EL). Optimal glucose and microcrystalline cellulose transformation conditions resulted in yields of 41.05 weight% and 38.56 weight% for EL, 0.73 weight% and 2.63 weight% for ethyl-glucoside (EG), 0.42 weight% and 0.36 weight% for 5-hydroxymethylfurfural (HMF), and 2.18 weight% and 2.16 weight% for 5-ethoxy Me furfural (EMF), resp. Increasing the reaction time and temperature resulted in an optimized yield of EL. These increases also resulted in decreased EG and EMF yield, and the change trend of HMF was not significant. EMF, HMF, and EG are intermediates in the formation of EL. Finally, we concluded that biomass conversion occurs first through cellulose degradation to glucose followed by the production of EG through alcoholysis and hydrolysis and dehydration of the reaction products to produce EL.

Journal of Biobased Materials and Bioenergy published new progress about Liquefaction. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, COA of Formula: C7H12O3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pryde, David C. published the artcileThe discovery of potent small molecule activators of human STING, Safety of Ethyl 2-hydroxyacetate, the main research area is human STING activator preparation oxindole benzothiazine quinoline oxazine benzazepine; Cytokines; Immunotherapy; Interferon genes; STING.

The adaptor protein STING plays a major role in innate immune sensing of cytosolic nucleic acids, by triggering a robust interferon response. Despite the importance of this protein as a potential therapeutic target for serious unmet medical conditions including cancer and infectious disease there remains a paucity of STING ligands. Starting with a benzothiazinone series of weak STING activators (human EC50 ∼10μM) we identified several chemotypes with sub-micromolar STING activity across all the major protein polymorphs. An example compound I, based on an oxindole core structure, demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalized and primary cells and a cytokine induction fingerprint consistent with STING activation. Our study has identified several related series of potent small mol. human STING activators with potential to be developed as immunomodulatory therapeutics.

European Journal of Medicinal Chemistry published new progress about Homo sapiens. 623-50-7 belongs to class esters-buliding-blocks, name is Ethyl 2-hydroxyacetate, and the molecular formula is C4H8O3, Safety of Ethyl 2-hydroxyacetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Soelter, Jan published the artcileComputational exploration of molecular receptive fields in the olfactory bulb reveals a glomerulus-centric chemical map, SDS of cas: 5405-41-4, the main research area is dorsal olfactory bulb glomerulus centric chem map computational exploration.

Progress in olfactory research is currently hampered by incomplete knowledge about chem. receptive ranges of primary receptors. Moreover, the chem. logic underlying the arrangement of computational units in the olfactory bulb has still not been resolved. We undertook a large-scale approach at characterizing mol. receptive ranges (MRRs) of glomeruli in the dorsal olfactory bulb (dOB) innervated by the MOR18-2 olfactory receptor, also known as Olfr78, with human ortholog OR51E2. Guided by an iterative approach that combined biol. screening and machine learning, we selected 214 odorants to characterize the response of MOR18-2 and its neighboring glomeruli. We found that a combination of conventional physico-chem. and vibrational mol. descriptors performed best in predicting glomerular responses using nonlinear Support-Vector Regression. We also discovered several previously unknown odorants activating MOR18-2 glomeruli, and obtained detailed MRRs of MOR18-2 glomeruli and their neighbors. Our results confirm earlier findings that demonstrated tunotopy, i.e., glomeruli with similar tuning curves tend to be located in spatial proximity in the dOB. In addition, our results indicate chemotopy, i.e., a preference for glomeruli with similar physico-chem. MRR descriptions being located in spatial proximity. Together, these findings suggest the existence of a partial chem. map underlying glomerular arrangement in the dOB. Our methodol. that combines machine learning and physiol. measurements lights the way towards future high-throughput studies to deorphanise and characterize structure-activity relationships in olfaction.

Scientific Reports published new progress about Homo sapiens. 5405-41-4 belongs to class esters-buliding-blocks, name is Ethyl 3-hydroxybutanoate, and the molecular formula is C6H12O3, SDS of cas: 5405-41-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Soelter, Jan published the artcileComputational exploration of molecular receptive fields in the olfactory bulb reveals a glomerulus-centric chemical map, COA of Formula: C9H18O2, the main research area is dorsal olfactory bulb glomerulus centric chem map computational exploration.

Progress in olfactory research is currently hampered by incomplete knowledge about chem. receptive ranges of primary receptors. Moreover, the chem. logic underlying the arrangement of computational units in the olfactory bulb has still not been resolved. We undertook a large-scale approach at characterizing mol. receptive ranges (MRRs) of glomeruli in the dorsal olfactory bulb (dOB) innervated by the MOR18-2 olfactory receptor, also known as Olfr78, with human ortholog OR51E2. Guided by an iterative approach that combined biol. screening and machine learning, we selected 214 odorants to characterize the response of MOR18-2 and its neighboring glomeruli. We found that a combination of conventional physico-chem. and vibrational mol. descriptors performed best in predicting glomerular responses using nonlinear Support-Vector Regression. We also discovered several previously unknown odorants activating MOR18-2 glomeruli, and obtained detailed MRRs of MOR18-2 glomeruli and their neighbors. Our results confirm earlier findings that demonstrated tunotopy, i.e., glomeruli with similar tuning curves tend to be located in spatial proximity in the dOB. In addition, our results indicate chemotopy, i.e., a preference for glomeruli with similar physico-chem. MRR descriptions being located in spatial proximity. Together, these findings suggest the existence of a partial chem. map underlying glomerular arrangement in the dOB. Our methodol. that combines machine learning and physiol. measurements lights the way towards future high-throughput studies to deorphanise and characterize structure-activity relationships in olfaction.

Scientific Reports published new progress about Homo sapiens. 111-11-5 belongs to class esters-buliding-blocks, name is Methyl octanoate, and the molecular formula is C9H18O2, COA of Formula: C9H18O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kufel, Wesley D. published the artcileSuccessful treatment with secnidazole for trichomoniasis in the setting of metronidazole hypersensitivity, Recommanded Product: 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, the main research area is secnidazole metronidazole trichomoniasis nitazoxanide Trichomonas vaginalis; Secnidazole; Trichomonas vaginalis; metronidazole; nitazoxanide; trichomoniasis.

Limited effective treatment options currently exist for trichomoniasis management among patients with metronidazole hypersensitivity. We report a patient with a documented history of metronidazole hypersensitivity who initially was treated with nitazoxanide but demonstrated clin. and microbiol. failure. Secnidazole was subsequently used for treatment, which resulted in clin. and microbiol. cure without observation of cross-reactivity. Secnidazole may represent a potential treatment option for trichomoniasis in patients with metronidazole hypersensitivity after consultation with an infectious disease specialist.

International Journal of STD & AIDS published new progress about Homo sapiens. 55981-09-4 belongs to class esters-buliding-blocks, name is 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate, and the molecular formula is C12H9N3O5S, Recommanded Product: 2-((5-Nitrothiazol-2-yl)carbamoyl)phenyl acetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Yunchong published the artcileHighly Stable and Nonflammable Hydrated Salt-Paraffin Shape-Memory Gels for Sustainable Building Technology, Computed Properties of 142-90-5, the main research area is stable nonflammable hydrated salt paraffin memory gel.

Hydrated salts (salt hydrates) are highly promising low-temperature phase change materials (PCMs) due to their high cohesive energy d. and low cost. However, they exhibit phase separation, liquid leakage, and inherent supercooling, which hinder their applications in sustainable building technol. Here, we describe the design of a highly stable emulsion gel system (EmulGels) that exhibits nonflammable and shape-memory characteristics. Oleophilic paraffin and hydrophilic hydrated salts, both of which are excellent PCMs typically existing in sep. phases, are combined harmoniously in a gel by a templating water-in-oil Pickering emulsion. Latent heat values of the prepared EmulGels were up to 213.2 J/g (eicosane/disodium hydrogen phosphate dodecahydrate = 1:3). No leakage of eicosane was noticed after heating the EmulGels at 60 °C for 30 min, and the latent heat value remained almost unchanged following 500 thermal cycles. The EmulGel was specifically designed to enable dual-phase crosslinking, which effectively enhanced its shape stability, slowed down loss of water of crystallization in hydrated salts, and decreased the degree of supercooling. Nonflammable characteristic typically found in hydrated salts was also exhibited by the EmulGel, in combination with good mech. properties. The materials characteristics make EmulGels ideal candidates to serve as building construction interlayers for effective thermal building management.

ACS Sustainable Chemistry & Engineering published new progress about Heat storage. 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, Computed Properties of 142-90-5.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hayashi, Naoki published the artcileSolubility of thermostable alkyl phosphate ester copper complexes in poly(alkyl methacrylate) for near-infrared-absorbing dyes, HPLC of Formula: 142-90-5, the main research area is solubility alkylphosphate ester copper polyalkyl methacrylate IR absorbing dye.

To realize thermoplastic near-IR-absorbing resin materials with weak absorbance in the visible region, the solubility of thermostable alkyl phosphate ester copper complexes in poly(alkyl methacrylate) was investigated for their use as near-IR-absorbing dyes. C4-C12 alkyl phosphate ester copper complexes were synthesized and mixed with Bu methacrylate, 2-ethylhexyl methacrylate, and lauryl methacrylate at 0.10 mol/g copper ion in the monomer solution The obtained solutions were polymerized to prepare 3 mm resin plates, and the plate transparency was evaluated by a haze meter. 2-Ethylhexyl methacrylate solutions of the 2-ethylhexyl phosphate copper complex and the isodecyl phosphate copper complex maintained their transparency even after polymerization, so these two copper complexes show good solubility in poly(2-ethylhexyl methacrylate). Both of the resin plates have >80% visible light transmittance and <50% solar direct transmittance. Thus, these resin materials are suitable as window materials that require heat-shielding properties and transparency. Polymer Journal (Tokyo, Japan) published new progress about Heat shields. 142-90-5 belongs to class esters-buliding-blocks, name is Dodecyl 2-methylacrylate, and the molecular formula is C16H30O2, HPLC of Formula: 142-90-5.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics