On February 1, 2018, Veluri, Jagan Mohan Reddy; Mustoori, Sairam; Yeruva, Srinivasulu Reddy; Tapas, Barui; Jyothishwaran, Jyothishwaran; Kanduri, Venkata Sada Siva Rao; Furkhan, Tajamul; Malolanarasimhan, Krishnan; Murugan, Ravichandran Narayanasamy; Kedari, Chaitanyakumar; Vasker, Rakesh Goud; Desai, Sahejad published a patent.Name: (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate The title of the patent was Process for preparation, recovery and purification of lirapeptide as a ubiquitin fusion protein and it’s subsequent conversion to liraglutide. And the patent contained the following:
The present application relates to a process for the preparation of peptides or proteins or derivatives thereof by expression of synthetic oligonucleotide encoding desired protein or peptide in prokaryotic cell as ubiquitin fusion construct. The experimental process involved the reaction of (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate(cas: 53838-27-0).Name: (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate
The Article related to lirapeptide sequence ubiquitin fusion protein liraglutide conversion, Fermentation and Bioindustrial Chemistry: Pharmaceuticals (Including Nutrients) and other aspects.Name: (S)-5-tert-Butyl 1-methyl 2-aminopentanedioate
Referemce:
Ester – Wikipedia,
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