On September 3, 1998, Hardy, Jean-claude; Bouquerel, Jean; Nemecek, Patrick; Aloup, Jean-claude; Mignani, Serge; Peyronel, Jean-francois published a patent.Application of 141940-37-6 The title of the patent was Preparation of 2-iminothiazolo[5,4,3-ij]quinolines and analogs as glutamatergic antagonists. And the patent contained the following:
Title compounds [I; R1 = H or alkyl; R6 = fluoroalkyl, -alkoxy, -alkylthio; R7 = H or alkyl, CH2OH, CH2NH2, alkylsulfonylmethyl, etc. only when Z = CH2CH2; Z = CH2CH2, CH(OH)CF2, COCH2, SO0-2CH2, etc.; Z1 = S or Se] were prepared Thus, 4-(F3CO)C6H4NH2 was cyclocondensed with HOCH(CH2OH)2 and the hydrogenated product cyclocondensed with KCNS to give I (R2 = R7 = H, R6 = OCF3, Z = CH2CH2, Z1 = S). Data for biol. activity of I were given. The experimental process involved the reaction of tert-Butyl (4-(trifluoromethyl)phenyl)carbamate(cas: 141940-37-6).Application of 141940-37-6
The Article related to iminothiazoloquinoline preparation glutamatergic antagonist, Heterocyclic Compounds (More Than One Hetero Atom): Thiazoles, Isothiazoles and other aspects.Application of 141940-37-6
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