Brown, Christopher A.; Aggarwal, Varinder K. published an article in 2015, the title of the article was Short Convergent Synthesis of the Mycolactone Core Through Lithiation-Borylation Homologations.Formula: C5H10O3 And the article contains the following content:
Using iterative lithiation-borylation homologations, the mycolactone toxin core (I) has been synthesized in 13 steps and 17% overall yield. The rapid build-up of mol. complexity, high convergence and high stereoselectivity are noteworthy features of this synthesis. The experimental process involved the reaction of (R)-Methyl 3-hydroxybutanoate(cas: 3976-69-0).Formula: C5H10O3
The Article related to mycolactone core preparation stereoselective lithiation borylation homologation, asymmetric synthesis, boron, iterative homologation, mycolactone, natural products, Biomolecules and Their Synthetic Analogs: Other Bacterial and Fungal Metabolites and other aspects.Formula: C5H10O3
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