Tag: M.W=250-300

Buechert, Marina; Steenbock, Torben; Lukaschek, Christian; Wolff, Marie C.; Herrmann, Carmen; Heck, Juergen published the artcile< 2,2'-Bipyridine-Based Dendritic Structured Compounds for Second Harmonic Generation>, Quality Control of 112-63-0, the main research area is dendritic bipyridine second harmonic generation; amino compounds; bipyridine ligand; dendrimers; hyper-Rayleigh scattering; nonlinear optics.

Parallel alignment of dipolar electron-donor-π-bridge-electron-acceptor entities can strongly enhance their nonlinear optical properties. This favorable arrangement can be in principle achieved by linking these units covalently or through metal coordination. Four dipolar single-strand chromophores decorated with a 5-electron-donor-5′-electron-acceptor-modified 2,2′-bipyridine functionality were synthesized. For two of these chromophores triple-stranded dendritic structures were successfully formed. All of the compounds were characterized with respect to their linear and nonlinear optical properties. For the aldehyde derivatives an enhancement of the first hyperpolarizability of 4.5 rather than 3 was obtained when going from single to triple strands. Theor. calculations with d. functional theory suggest that interstrand transitions contribute to the optical properties of the dendritic structures.

Chemistry – A European Journal published new progress about Crystal structure. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Eldemerdash, Marwa M.; El-Sayed, Ashraf S. A.; Hussein, Hussein A.; Teleb, Samir S.; Shehata, Rania S. published the artcile< Molecular and metabolic traits of some Egyptian species of Cassia L. and Senna Mill (Fabaceae-Caesalpinioideae)>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is Cassia Senna metabolism Egypt; Cassia; GC-MS profile; ITS sequence; RAPD analysis; Senna; Taxonomical features.

The genus Cassia and Senna have been classified under subfamily Caesalpinioideae of family Fabaceae (Leguminosae) of order Fabales. There is a scarce taxonomical studies of the genus Cassia and Senna inhabiting Egyptian environments, thus, the main objective of the current was to revise and authenticate the phylogenetic relationship between studied taxa of the species of the genera Cassia and Senna in Egypt using the recent tools of ITS barcoding, RAPD anal. and metabolic profiling, in comparing to the traditional taxonomical features. From the cluster anal. of the traditional 27 morphol. characters, the studied taxa were categorized into two major clades with an average taxonomic distance of 4.3. The clade I include Cassia fistula, C. renigera, C. javanica L subsp. nodosa and C. roughiia that belongs to series Obolospermae, and C. grandis that belongs to series Grandes. The clade (II) includes Senna surattensis and S. alata at taxonomic level 3.6. The taxonomical description of the studied taxa was confirmed from the mol. anal. of ITS sequences and RAPD anal. The ITS sequences of the tested plants species C. fistula L, C. grandis MD4, C. javanica subsp. nodosa MD7, C. roxburghii MD5, C. renigera MD5 were deposited at genbank with accession numbers MW367973, MZ960447, MW386305, MW326753 and MW32685, resp. While, the ITS sequences of the S. surrattensis and S. alata were deposited into genbank accession # MD14 MW367670 and MD20 MW412635, resp. Thus, from the mol. anal., two clades were clearly separated into Clade I of Cassia and Clade II of Senna. The cluster I represented by C. fistula, C. renigera, C. roxburghii, and C. javanica sub nodosa, and the cluster II represented by S. alata and S. surattensis. From the PCA of RAPD, a clearly discrimination between the two Taxa was observed revealing the characteristic grouping of Cassia and Senna. The species Senna alata and Senna surattensis were grouped together, but the species of C. renigera, C. javanica, C. roxburghii and C. grandis was grouped on a distinct group. The separation of Cassia and Senna species into two clusters verify the segregation of the genus Cassia L. senso lato into two distinct genera namely Senna P. and Cassia L. The morphol., mol. traits of the studied plants were authenticated from the metabolic profiling by GC-MS anal. Among the 23 identified metabolites, four compounds namely hexadecanoic acid, Me ester, 9-Octadecenoic acid (Z)-Et ester and Vitamin E were detected with fluctuated concentrations, among C. fistula, C. grandis, C. javanica subsp. nodosa and C. roxburghii. Conclusively, the traditional morphol. features, mol. barcoding using ITS sequences, RAPD anal. and metabolic traits by GC-MS anal., authenticates the taxonomical diversity of the genus Cassia and Senna.

BMC Plant Biology published new progress about Caesalpinioideae. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zheng, Ruixin; Shu, Chaozhu; Li, Jiabao; Hu, Anjun; Chen, Nian; Li, Minglu; Long, Jianping published the artcile< Oxygen vacancy engineering of vertically aligned NiO nanosheets for effective CO2 reduction and capture in Li-CO2 battery>, COA of Formula: C19H34O2, the main research area is oxygen vacancy vertically aligned nickel oxide nanosheet; carbon dioxide reduction capture lithium battery.

The Li-CO2 battery with the concept of turning waste into treasure has aroused great scientific research enthusiasm recently, but unfortunately it is a long shot for the large-scale applications of Li-CO2 battery due to its huge overpotential and poor cycling life at current stage. Herein, NiO nanosheets engineered by O vacancy growing vertically on C clothes (NiO-Vo@CC) was developed as viable catalyst for both CO2 reduction reaction (CO2RR) and CO2 evolution reaction (CO2ER) in Li- CO2 system. The O vacancy decorated by surplus electron will not only work as electron donor (Lewis base) surface to activated the electron-deficient C atom in CO2 but also narrow the band gap of NiO, therefore optimized CO2 conversion kinetic can be obtained by using defective NiO-Vo@CC electrode. The use of defect engineering to achieve performance improvement in aprotic Li-CO2 battery is still in its infancy at current stage and thus the authors’ research initially corroborates that modulation of the surface property via defect engineering can serve as valid strategy to design high performance electrodes for Li-CO2 battery.

Electrochimica Acta published new progress about Carbon fibers, fabrics Role: CAT (Catalyst Use), TEM (Technical or Engineered Material Use), USES (Uses). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Loenarz, Christoph; Mecinovic, Jasmin; Chowdhury, Rasheduzzaman; McNeill, Luke A.; Flashman, Emily; Schofield, Christopher J. published the artcile< Evidence for a stereoelectronic effect in human oxygen sensing>, Synthetic Route of 112-63-0, the main research area is stereoelectronic effect human oxygen sensing; proline conformation prolyl hydroxylase pVHL specificity.

How PHDs achieve specificity: trans-4-prolyl hydroxylation of the transcription factor HIF occurs with stereochem. retention. Substrate-analog studies show how the von Hippel Lindau tumor suppressor protein (pVHL) and the oxygen-sensing hydroxylases (PHDs) achieve specificity for hydroxyprolyl/prolyl residues for the C4-exo/endo prolyl conformations, resp.

Angewandte Chemie, International Edition published new progress about Homo sapiens. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhao, Chenglong; Jia, Xiao; Schols, Dominique; Balzarini, Jan; Meier, Chris published the artcile< γ-Non-Symmetrically Dimasked TriPPPro Prodrugs as Potential Antiviral Agents against HIV>, SDS of cas: 112-63-0, the main research area is HIV antiviral prodrug; antiviral agents; bioreversible protection; nucleoside analogue; nucleoside triphosphate prodrugs; nucleotides.

Nucleoside analog reverse transcriptase inhibitors (NRTI) and nucleoside analog monophosphate prodrugs are used in combination antiretroviral therapy (cART). The design of antivirally active nucleoside triphosphate prodrugs is a recent and an important advancement in the field of nucleoside analog drug development. Here, we report on TriPPPro-derivatives of nucleoside analog triphosphates (NTPs) that comprised two different acyloxybenzyl-masks at the γ-phosphate of the NTP aiming to achieve the metabolic bypass. Thus, γ-non-sym. dimasked TriPPPro-compounds (γ-(AB,ab)-d4TTPs) were synthesized and they proved to be active against HIV-1 and HIV-2 in cultures of infected wild-type human CD4+ T-lymphocyte (CEM/0) cells and more importantly also in thymidine kinase-deficient CD4+ T-cells (CEM/TK-). From hydrolysis studies both in phosphate buffer (PB, pH 7.3) and CEM cell extracts, there was surprisingly no differentiation in the cleavage of the two acyloxybenzyl prodrug-masks. However, if within one of the two acyloxybenzyl groups a short PEG-type methoxytriglycol group was introduced, the “”standard”” acyloxybenzyl-mask was cleaved with high preference.

ChemMedChem published new progress about Anti-HIV agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, SDS of cas: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Gao, Jia; Jiang, Donglin published the artcile< Covalent organic frameworks with spatially confined guest molecules in nanochannels and their impacts on crystalline structures>, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is covalent organic framework guest nanopore crystal structure.

The authors demonstrate the profound effects of spatially confined guest mols. in one-dimensional nanochannels on X-ray diffraction of covalent organic frameworks. The results give insights into the abnormal X-ray diffraction patterns and suggest a mol. dynamic strategy for resolving crystalline structures.

Chemical Communications (Cambridge, United Kingdom) published new progress about Covalent organic frameworks. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Safety of (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Huenerhoff, Ernst published the artcile< Pyridinium perbromide, a mild brominating agent for carbon-carbon double bonds>, Computed Properties of 112-63-0, the main research area is bromination olefin pyridinium perbromide.

Compounds containing double bonds, i.e. cyclohexene, styrene, and vitamin C, were treated with pyridinium perbromide (I), prepared from pyridine reaction with HBr and Br to give the corresponding Br addition compounds

Praxis der Naturwissenschaften, Chemie published new progress about Alkenes Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Computed Properties of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Fan, Yan-Hua; Li, Wei; Liu, Dan-Dan; Bai, Meng-Xuan; Song, Hong-Rui; Xu, Yong-Nan; Lee, SangKook; Zhou, Zhi-Peng; Wang, Jian; Ding, Huai-Wei published the artcile< Design, synthesis, and biological evaluation of novel 3-substituted imidazo[1,2-a]pyridine and quinazolin-4(3H)-one derivatives as PI3Kα inhibitors>, Quality Control of 112-63-0, the main research area is imidazo pyridine quinazolinone preparation PI3K alpha inhibitor anticancer agent; Anticancer agents; Imidazo[1,2-a]pyridine; PIK3CA gene; Phosphatidylinositol 3-kinase; Quinazolin-4(3H)-one.

Phosphatidylinositol 3-kinase (PI3K) is a pivotal regulator of intracellular signaling pathways and considered as a promising target in the development of a therapeutic treatment of cancer. Among the different PI3K subtypes, the PIK3CA gene encoding PI3K p110α is frequently mutated and overexpressed in majority of human cancers. Therefore, the inhibition of PI3Kα has been considered to be an efficient approach for the treatment of cancer. In this study, two series compounds containing hydrophilic group in imidazo[1,2-a]pyridine and quinazolin-4(3H)-one were synthesized and their antiproliferative activities against five cancer cell lines, including HCT-116, SK-HEP-1, MDA-MB-231, SNU638 and A549, were evaluated. Compound I with most potent antiproliferative activity was selected for further biol. evaluation. PI3K kinase assay showed that I has selectivity for PI3Kα distinguished from other isoforms. The western blot assay indicated that I is more effective than HS-173, an imidazopyridine-based PI3Ka inhibitor, in reducing the levels of phospho-Akt. All these results suggested that I is a potent PI3Kα inhibitor and could be considered as a potential candidate for the development of anticancer agents.

European Journal of Medicinal Chemistry published new progress about Antitumor agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Alvarez-Lorenzo, Carmen; Hiratani, Haruyuki; Tanaka, Kazunori; Stancil, Kimani; Grosberg, Alexander Yu.; Tanaka, Toyoichi published the artcile< Simultaneous Multiple-Point Adsorption of Aluminum Ions and Charged Molecules by a Polyampholyte Thermosensitive Gel: Controlling Frustrations in a Heteropolymer Gel>, Formula: C19H34O2, the main research area is multiple point adsorption polyampholyte hydrogel swelling; aluminum ion adsorption polyampholyte gel.

Data on concurrent multiple point adsorption of two oppositely charged species of “”target mols.”” (aluminum ions and 1,3,6,8-pyrenetetrasulfonic sodium salt (Py-4)) by a polyampholyte gel of N-isopropylacrylamide (NIPA, 6 M) with methacrylic acid (MAA, 80 mM) and methacrylamidopropyl trimethylammonium chloride (MAPTAC, 80 mM) is reported. The goal of this study is to test the mutual frustrations created by adsorption of one species on the adsorption of the other. Understanding these frustrations is an important step toward elucidating the memory of conformations in heteropolymer systems. It was found that in the absence of aluminum, the adsorption of Py-4 was suppressed by gel collapse, presumably because of an increase in MAA/MAPTAC ionic pairs that prevents the formation of potential adsorbing centers. Adding a moderate amount of aluminum significantly enhances adsorption of Py-4 by the collapsed gel, indicating that aluminum ions compete for bonds with MAA and help release vacant MAPTAC centers. Finally, with further increase of aluminum, the Py-4 multiple point adsorption is again suppressed, pointing out the frustrations created by aluminum-mediated effective cross-links. The cooperativity of the adsorption process is also analyzed.

Langmuir published new progress about Adsorption. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Williams, Davdi R.; Li, Jie published the artcile< Total synthesis of myxovirescin A1>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is myxovirescin A1 total synthesis.

Stereocontrolled synthesis of myxovirescin A1, a 28-membered macrolactam lactone, is accomplished via a highly convergent route. Ring closure to the macrocycle is realized by macro-lactamization of azido acid I using the Mukaiyama procedure.

Tetrahedron Letters published new progress about 112-63-0. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics