Tag: M.W=250-300

He, Zemin; Yu, Ping; Zhao, Yuzhen; Zhang, Huimin; Zhang, Yongming; Kang, Xiaoxi; Zhang, Haiquan; Sadeghzadeh, Seyed Mohsen published the artcile< PrVO4/SnD NPs as a Nanocatalyst for Carbon Dioxide Fixation to Synthesis Benzimidazoles and 2-Oxazolidinones>, Electric Literature of 112-63-0, the main research area is PrVO4 SnD nanocatalyst carbon dioxide fixation benzimidazole oxazolidinone.

Recently CO2 stabilization has received a great deal of attention because of its probable applications as a rich C1 resource and the synthesis of several fine chems. can be accomplished through this stabilization. In this study, Sn(IV) doping dendritic fibrous nanosilica (SnD) supported PrVO4 nanoparticles as a catalyst (PrVO4/SnD) was synthesized by a in-situ procedure. The SnD with the ratios of Si/Sn in a variety of 6 to 40 were acquired through direct hydrothermal synthesis (DHS), and PrVO4 NPs on the surfaces of SnD were reduced in-situ. X-Ray diffraction (XRD), Scanning electron microscope (SEM), Fourier transform IR spectroscopy (FT-IR), transmission electron microscopy (TEM), and X-ray energy dispersive spectroscopy (EDS) were deployed for identifying the PrVO4/SnD. It is potentially a highly dynamic catalyst in the stabilization of CO2 for the production of 2-oxazolidinones and benzimidazoles. In addition, the catalyst is very easy to recycle and reuse without significant loss of active site Cu metal.

Catalysis Letters published new progress about Carbon sequestration. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Electric Literature of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Sun, Zhonghe; Mi, Xing; Yu, Yanan; Shi, Wencheng; Feng, Anchao; Moad, Graeme; Thang, San H. published the artcile< ""All-PVC"" Flexible Poly(vinyl Chloride): Nonmigratory Star-Poly(vinyl Chloride) as Plasticizers for PVC by RAFT Polymerization>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is PVC flexible polyvinyl chloride polyvinyl plasticizer RAFT polymerization.

Xanthate-mediated RAFT polymerization has been used to prepare 3-star and 4-star-poly(vinyl chloride) (star-PVC) with a number average molar mass (Mn) in the range of 1 to 7 kg mol-1. The Tg of star-PVC reduces with molar mass and with the number of arms. The star-PVC have substantially lower glass-transition temperatures (Tg) than that of linear PVC of similar Mn, with the Tg of low-molar mass 4-star-PVC being -7.4°C. The star-PVC are effective in lowering the Tg of blends with com. PVC when added at 10-30 weight % PVC. When added even at 10 weight %, they are effective in improving the ductility of PVC with an elongation at break (EB) of ~350% (4-star-PVC) and ~300% (3-star-PVC) relative to com. PVC, which is substantially higher than that for PVC conventionally plasticized with 30 weight % dioctyl phthalate under similar conditions (EB ~160%). Importantly, the star-PVC, despite their low molar mass, do not migrate from the PVC blends when tested under standard conditions. The performance of the star-PVC as non-migratory plasticizers for PVC demonstrates the potential for an “”all-PVC”” flexible PVC.

Macromolecules (Washington, DC, United States) published new progress about Ductility. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Tchani, G.; Baziard-Mouysset, G.; Younes, S.; Bellan, J.; Payard, M.; Stigliani, J. L.; Grassy, G.; Bonnafous, R.; Tisne-Versailles, J. published the artcile< Evaluation of calcium inhibitory activity of a series of diethyl benzylphosphonates>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is calcium antagonist benzylphosphonate; structure activity relationship calcium channel blocking; cardiodepressive benzylphosphonate.

Thirty-nine di-Et benzylphosphonates (12 newly prepared) related to Fostedil were evaluated as calcium antagonists, using the inhibition test on aortic contraction in the rabbit, which was more selective than the neg. inotropic activity test on guinea-pig left atrial muscle. Six compounds had weak activity compared with Fostedil. Structure-activity relationships indicated a certain lipophilic influence; no correlation was found with electronic parameters. The prerequisite structure to obtain active products seems to require two conjugated aromatic rings separated by an optimal distance.

European Journal of Medicinal Chemistry published new progress about Calcium channel blockers. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Fu, Kun; Liu, Chenxu; Wang, Lemeng; Huang, Xiayu; Fu, Dong published the artcile< Performance and mechanism of CO2 absorption in 2-ethylhexan-1-amine + glyme non-aqueous solutions>, SDS of cas: 112-63-0, the main research area is carbon dioxide glyme ethylhexan amine absorption.

In this work, novel non-aqueous absorbents composed of 2-ethylhexan-1-amine (EHA) and glyme were proposed for CO2 capture. The absorption performance of CO2 in EHA + diglyme, EHA + triglyme and EHA + tetraglyme non-aqueous solutions was investigated and the viscosities (η) of the CO2-saturated absorbents were measured. Besides the experiments, kinetic models were applied to correlate the CO2 absorption. The activation energy (Ea) was obtained from Arrhenius equation, and the absorption mechanism was deduced. The results showed that both Lagergren model and Avrami model can accurately correlate and predict the time-dependent absorption amount, thus an optimized composition under which excellent absorption performance and relatively low η and Ea can be simultaneously achieved was determined Compared to water-based absorbents like MEA, the optimized non-aqueous absorbents take the advantages of better absorption performance and lower activation energy. Moreover, the glyme solvents have about 50% lower sp. heat capacities and much higher b.ps. (≥435 K) than water, which is expected to greatly reduce the sensible heat and the latent heat of the solvent during regeneration. Therefore, the proposed novel absorbents have promising industrial application potential in the CO2 capture process.

Energy (Oxford, United Kingdom) published new progress about Absorption. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, SDS of cas: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Dinakaran, Paul M.; Bhagavannarayana, G.; Kalainathan, S. published the artcile< Synthesis, growth, structural, optical, spectral, thermal and mechanical studies of 4-methoxy 4-nitrostilbene (MONS): A new organic nonlinear optical single crystal>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is methoxy nitrostilbene optical nonlinear crystal synthesis; luminescence methoxy nitrostilbene optical nonlinear crystal synthesis; DTA methoxy nitrostilbene optical nonlinear crystal synthesis; thermogravimetry methoxy nitrostilbene optical nonlinear crystal synthesis; thermal analysis methoxy nitrostilbene optical nonlinear crystal synthesis; NMR methoxy nitrostilbene optical nonlinear crystal synthesis; UV visible spectra methoxy nitrostilbene optical nonlinear crystal synthesis; near IR spectra methoxy nitrostilbene optical nonlinear crystal synthesis; mid IR spectra methoxy nitrostilbene optical nonlinear crystal synthesis; XRD methoxy nitrostilbene optical nonlinear crystal synthesis; microhardness methoxy nitrostilbene optical nonlinear crystal synthesis; lattice parameter methoxy nitrostilbene optical nonlinear crystal synthesis; structure crystal methoxy nitrostilbene optical nonlinear synthesis; second harmonic generation nitrostilbene optical nonlinear crystal synthesis.

4-Methoxy 4-nitrostilbene (MONS), a new organic nonlinear optical material was synthesized. Based on the solubility data good quality single crystal with dimensions up to 38 × 11 × 3 mm3 was grown by slow evaporation method using Et Me ketone (MEK) as a solvent. Powder XRD confirms the crystalline property and also the diffraction planes were indexed. The lattice parameters for the grown MONS crystals were determined by using single crystal x-ray diffraction anal. and it reveals that the crystal lattice system is triclinic. The crystalline perfection of the grown crystals was analyzed by high resolution x-ray diffraction (HRXRD) rocking curve measurements. FTIR spectrum for powd. MONS sample confirms the functional groups present in the grown crystal. The UV-visible absorption spectrum was recorded at 190-1100 nm and the cut off wavelength 499 nm was determined The optical constants of MONS were determined through UV-visible-NIR spectroscopy. The MONS crystals were further subjected to other characterizations. i.e., 1H NMR, TG/DTA, photoluminescence and microhardness test. The Kurtz and Perry powder technique confirms the NLO property of the grown crystal and the SHG efficiency of MONS is 1.55× greater than that of KDP crystal.

Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy published new progress about Absorptivity. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Demont, Emmanuel H.; Bamborough, Paul; Chung, Chun-wa; Craggs, Peter D.; Fallon, David; Gordon, Laurie J.; Grandi, Paola; Hobbs, Clare I.; Hussain, Jameed; Jones, Emma J.; Le Gall, Armelle; Michon, Anne-Marie; Mitchell, Darren J.; Prinjha, Rab K.; Roberts, Andy D.; Sheppard, Robert J.; Watson, Robert J. published the artcile< 1,3-Dimethyl Benzimidazolones Are Potent, Selective Inhibitors of the BRPF1 Bromodomain>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is benzimidazolone preparation bromodomain inhibitor; crystal structure; BRD1; BRPF1; BRPF2; BRPF3; bromodomain; chemical probe; epigenetics; fragment; inhibitor.

The BRPF (bromodomain and PHD finger-containing) protein family are important scaffolding proteins for assembly of MYST histone acetyltransferase complexes. Here, the authors report the discovery, binding mode, and structure-activity relationship (SAR) of the first potent, selective series of inhibitors of the BRPF1 bromodomain.

ACS Medicinal Chemistry Letters published new progress about Bromodomain-containing proteins Role: BSU (Biological Study, Unclassified), PRP (Properties), RCT (Reactant), BIOL (Biological Study), RACT (Reactant or Reagent) (crystal structure, complexes with di-Me benzimidazolones). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kantzanou, Maria; Karalexi, Maria A.; Zivinaki, Anduela; Riza, Elena; Papachristou, Helen; Vasilakis, Alexis; Kontogiorgis, Christos; Linos, Athina published the artcile< Concordance of genotypic resistance interpretation algorithms in HIV-1 infected patients: An exploratory analysis in Greece>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is Atazanavir Kaletra Saquinavir Tripranav antiHIV agent HIV1 infection; Antiretroviral drug; Genotypic resistance; HIV; Inter-algorithm interpretation discordances; Protease inhibitors.

Genotypic resistance-related mutations in HIV-1 disease are often difficult to interpret. Different algorithms have been developed to provide meaningful application into clin. context. We aimed to compare, for the first time in Greece, the results of genotypic resistance derived from three interpretation algorithms. The sequences of 120 HIV 1-infected patients were tested for genotypic resistance to 19 antiretroviral (ARV) drugs (n = 2280 sequences). The interpretation results of Rega, ANRS and ViroSeq algorithms were compared. Complete concordance was found for 2/19 ARV drugs, namely lamivudine and emptricitabine. Concordance was high for nucleoside reverse transcriptase inhibitors (NRTIs) and low for protease inhibitors (PIs). In inter-algorithm pairs, agreement was high between Rega and ViroSeq (kappa = 0.701), especially by ARV class, namely NRTIs (k = 0.869) and NNRTIs (k = 0.562). The only exception was noted for rilpivirine, where agreement was higher between ANRS and Rega (k = 0.410) compared to other inter-algorithm pairs (k = 0.018-0.055). By contrast, for PIs all comparisons yielded concordance equivalent to chance (k = 0.000). Our exploratory anal. provided evidence of significant inter-algorithm discordances, especially for PIs and NNRTIs highlighting the importance of matching the results of different algorithms to achieve optimized risk stratification. Ongoing research could assist clin. physicians in interpreting complex genotypic resistance patterns.

Journal of Clinical Virology published new progress about Anti-HIV agents. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Li; Jiao, Lei published the artcile< Visible-Light-Induced Organocatalytic Borylation of Aryl Chlorides>, Application of C19H34O2, the main research area is visible light catalyst organocatalytic borylation aryl chloride mechanism photoactivation; aryl boronate preparation.

The preparation of arylboronates from unactivated aryl chlorides in a transition-metal-free manner is rather challenging. There are only few examples to achieve this goal by using UV irradiation Based on the mechanistic understanding of the diboron/methoxide/pyridine reaction system, we achieved photoactivation of the in situ generated super electron donor and developed a visible-light-induced organocatalytic method for efficient borylation of unactivated aryl chlorides.

Journal of the American Chemical Society published new progress about Aryl chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Reinhardt, Luiza Steffens; Moras, Ana Moira; Henn, Jeferson Gustavo; Arantes, Pablo Ricardo; Ferro, Matheus Bernardes; Braganhol, Elizandra; de Souza, Priscila Oliveira; de Oliveira Merib, Josias; Borges, Gabriela Ramos; Dalanhol, Carolina Silveira; de Barros Dias, Mabilly Cox Holanda; Nugent, Michael; Moura, Dinara Jaqueline published the artcile< Nek1-inhibitor and temozolomide-loaded microfibers as a co-therapy strategy for glioblastoma treatment>, Reference of 112-63-0, the main research area is Drug delivery systems; Electrospinning; Glioblastoma; Microfibers; NIMA-related kinase 1; Polyvinyl alcohol; Temozolomide.

Malignant glioblastoma (GB) is the predominant primary brain tumor in adults, but despite the efforts towards novel therapies, the median survival of GB patients has not significantly improved in the last decades. Therefore, localised approaches that treat GB straight into the tumor site provide an alternative to enhance chemotherapy bioavailability and efficacy, reducing systemic toxicity. Likewise, the discovery of protein targets, such as the NIMA-related kinase 1 (Nek1), which was previously shown to be associated with temozolomide (TMZ) resistance in GB, has stimulated the clin. development of target therapy approaches to treat GB patients. In this study, we report an electrospun polyvinyl alc. (PVA) microfiber (MF) brain-implant prepared for the controlled release of Nek1 protein inhibitor (iNek1) and TMZ or TMZ-loaded nanoparticles. The formulations revealed adequate stability and drug loading, which prolonged the drugs′ release allowing a sustained exposure of the GB cells to the treatment and enhancing the drugs′ therapeutic effects. TMZ-loaded MF provided the highest concentration of TMZ within the brain of tumor-bearing rats, and it was statistically significant when compared to TMZ via i.p. (IP). All animals treated with either co-therapy formulation (TMZ + iNek1 MF or TMZ nanoparticles + iNek1 MF) survived until the endpoint (60 days), whereas the Blank MF (drug-unloaded), TMZ MF and TMZ IP-treated rats′ median survival was found to be 16, 31 and 25 days, resp. The tumor/brain area ratio of the rats implanted with either MF co-therapy was found to be reduced by 5-fold when compared to Blank MF-implanted rats. Taken together, our results strongly suggest that Nek1 is an important GB oncotarget and the inhibition of Nek1′s activity significantly decreases GB cells′ viability and tumor size when combined with TMZ treatment.

International Journal of Pharmaceutics (Amsterdam, Netherlands) published new progress about 112-63-0. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Canella Vieira, Bruno; Sousa Alves, Guilherme; Vukoja, Barbara; Velho, Vinicius; Zaric, Milos; Houston, Trenton W.; Fritz, Bradley K.; Kruger, Greg R. published the artcile< Spray drift potential of dicamba plus S-metolachlor formulations>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is S metolachlor Amaranthus formulation spray drift potential; capsule suspension; crop injury; emulsifiable concentrate; off-target movement; premix; tankmix.

Early-postemergence herbicide applications in the USA often include residual herbicides such as S-metolachlor to suppress late late-emerging Amaranthus spp. Although this practice benefits weed control, herbicide tankmixes can influence spray droplet size and drift potential during applications. The addition of S-metolachlor products to dicamba spray solutions generally decreases spray droplet size and increases spray drift potential. Advances in formulation technol. fostered the development of products with reduced spray drift potential, especially for herbicide premixes containing multiple active ingredients. The objective of this study was to compare the drift potential of a novel dicamba plus S-metolachlor premix formulation (capsule suspension) against a tankmix containing dicamba (soluble liquid) and S-metolachlor (emulsifiable concentrate) using different venturi nozzles. The MUG nozzle had greater DV0.5 (1128.6μm) compared to the ULDM (930.3μm), TDXL-D (872.9μm), and TTI nozzles (854.8μm). The premix formulation had greater DV0.5 (971.0μm) compared to the tankmix (922.3μm). Nozzle influenced spray drift deposition (P < 0.0001) and soybean biomass reduction (P = 0.0465). Herbicide formulation influenced spray drift deposition (P < 0.0001), and biomass reduction of soybean (P < 0.0001) and cotton (P = 0.0479). The novel capsule suspension formulation (premix) of dicamba plus S-metolachlor had reduced area under the drift curve (AUDC) (577.6) compared to the tankmix (913.7). Applications using the MUG nozzle reduced AUDC (459.9) compared to the other venturi nozzles (ranging from 677.4 to 1141.7). Study results evidence that advances in pesticide formulation can improve pesticide drift mitigation. Pest Management Science published new progress about Amaranthus. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics