Tag: M.W=250-300

Li, Zhimao; Li, Yingchun; He, Maoyong; Wang, Wensheng; Li, Jie published the artcile< Effects of the species of crosslinking reagents on the structures and properties of biodegradable poly (butanediol sebacate-butanediol terephthalate) copolyester>, Synthetic Route of 112-63-0, the main research area is polybutylene sebacate terephthalate crosslinking agent esterification polycondensation; mech thermal property.

In the present study, poly(butylene sebacate-co-terephthalate)s having different crosslinking reagents were synthesized with a random distribution by a two-step esterification and one-step polycondensation process. In detail, the using crosslinking agents were included trimethylolethane (TME), trimethylolpropane, tris(hydroxymethyl)aminoethane, glycerol (GL). Particularly, CS refers to a sample with no crosslinking agent added. The copolyester with TME was the least crystalline sample, and the melting peaks of all copolyesters corresponding to both, sebacate and terephthalate-rich phases were still observable in second calorimetric heating runs. These copolyesters were associated with interesting thermal and mech. properties. The m.ps. of all samples were higher than 118°C and the puncture resistance and tensile strength of GL, the tear strength of TME, and the Young’s modulus of all samples have been improved. Enzymic degradability was assessed and the effect of composition and crystallinity on the degradation rate was investigated. The copolyester adding GL appears as a highly promising biodegradable material since it showed a significant weight loss during exposure to all selected degradation media. In brief, the improvement of PBSeT’s puncture resistance, tear strength, and degradation performance is extremely important for the development and promotion of degradable foam, film, and elastomer materials.

Journal of Applied Polymer Science published new progress about Breaking strength. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Synthetic Route of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chen, Zhi-Min; Yang, Bin-Miao; Chen, Zhi-Hua; Zhang, Qing-Wei; Wang, Min; Tu, Yong-Qiang published the artcile< Organocatalytic Asymmetric Fluorination/Semipinacol Rearrangement: An Efficient Approach to Chiral β-Fluoroketones>, Reference of 112-63-0, the main research area is chiral fluoro ketone preparation; oxa allylic alc preparation asym fluorination semipinacol rearrangement; cinchona alkaloid catalyst asym fluorination semipinacol rearrangement.

Fluorination/semipinacol rearrangement of 2-oxa allylic alcs. was catalyzed by cinchona-alkaloid derivatives in an asym. manner. E.g., in presence of ((DHQD)2PYR), K2CO3, and NFSI in ClCH2CH2Cl, fluorination/semipinacol rearrangement of alc. (I) gave 56% β-fluoro ketone (S,S)-II (93% ee). Use of the catalyst ((DHQ)2PYR) in this reaction gave ent-II.

Chemistry – A European Journal published new progress about Allylic alcohols Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Katoh, H.; Ishida, T.; Kuwata, Shinichi; Kiniwa, H. published the artcile< Optical resolution of 2-hydroxy acids by high-performance ligand exchange chromatography>, Computed Properties of 112-63-0, the main research area is ligand exchange HPLC hydroxy acid; hydroxy carboxylic acid resolution HPLC; iron reagent amino hydroxy acid distinction; liquid chromatog resolution amino hydroxy acid; beverage analysis amino hydroxy acid; octylalanine chiral phase HPLC resolution.

Using an MCI GEL CRS10W column, which was packed with octadecyl silica coated with N,N-dioctyl-L-alanine, optical resolution of 2-hydroxy acids was performed by ligand-exchange HPLC. The optical resolution of mandelic acid derivatives and C2 to C5 2-hydroxy acids was carried without any pretreatment. The MCI GEL CRS10W column could resolve amino acids and 2-hydroxy acids. For their selective detection, a post-column method was employed in which the specific color reaction of 2-hydroxy acids with iron(III) ion was utilized. For the anal. of beverages, in which amino acids and 2-hydroxy acids often coexist, the present method was effective in distinguishing between these enantiomers.

Chromatographia published new progress about Amino acids Role: BIOL (Biological Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Computed Properties of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Shugaev, A. G.; Butsanets, P. A.; Shugaeva, N. A. published the artcile< Effect of High Temperature on Oxidation of NAD-Dependent Substrates and Alternative Oxidase Activity in Mitochondria of Lupine Cotyledons>, Category: esters-buliding-blocks, the main research area is NAD oxidation temperature alternative oxidase mitochondria Lupine.

Isolated mitochondria from lupine (Lupinus angustifolius L.) cotyledons were used to study the effect of temperature in the range of 20-40°C on oxidation of malate and other NAD-dependent respiratory substrates as well as on the activity of alternative CN-resistant oxidase. The metabolic responses of mitochondria to heat treatment analyzed in vitro were compared with metabolic activities of organelles isolated from seedlings exposed to elevated temperature in vivo. Mild warming of the incubation medium (20-30°C) accelerated oxygen uptake by mitochondria during malate oxidation in the presence of glutamate in the active phosphorylating state (state 3) and, to a lesser extent, in the state 4 (in the absence of ADP). The enhancement of mitochondrial respiration at increasing temperature in this range was entirely due to the activation of the cytochrome pathway in electron-transport chain (ETC). At temperatures of 35-40°C, an appreciable inhibition of the alternative respiration pathway was observed The successive additions of ADP during malate oxidation under hyperthermia (35-40°C) caused the improvement (phenomenon of conditioning) of oxidative phosphorylation parameters. After the second addition of 100-200μM ADP, the rate of substrate oxidation in state 3 and the respiratory control ratio (RCR) increased significantly. Similar changes in mitochondrial respiration under hyperthermia were found upon oxidation of other NAD-dependent substrates, but they did not occur during succinate oxidation catalyzed by ETC complex II. In mitochondria isolated from cotyledons of lupine seedlings that were exposed in vivo to high temperature (35°C for 12 h), the malate oxidation at 25 or 35°C was also characterized by a sharp decrease in RCR and the state 3 rate after the first addition of ADP, but these parameters were restored during several cycles of phosphorylation. Oxidation of malate and other NAD-dependent substrates catalyzed by complex I after heating of mitochondria at 40°C in the presence of 10 mM MgCl2 was substantially inhibited and was carried out by rotenone-insensitive NADH dehydrogenases. The results suggest that the suppressed oxidation of NAD-dependent substrates in lupine cotyledon mitochondria at high temperature is probably due to the reversible transformation of complex I from the active to the deactivated form (A/D transition). Possible physiol. significance of such regulatory changes in plant respiration in response to adverse environmental conditions is discussed.

Russian Journal of Plant Physiology published new progress about Cotyledon. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ignatiuk, Zaneta A.; Janicki, Mikolaj J.; Gora, Robert W.; Konieczny, Krzysztof; Kowalczyk, Rafal published the artcile< Applications of Thermal Activation, Ball-milling and Aqueous Medium in Stereoselective Michael Addition of Nitromethane to En-ynones Catalyzed by Chiral Squaramides>, HPLC of Formula: 112-63-0, the main research area is nitromethane enynone chiral squaramide enantioselective regioselective Michael addition; nitromethyl aryl phenyl pentynone.

Stereoselective addition of nitromethane to conjugated en-ynones was performed through the application of chiral squaramides. Three non-classical approaches to promote the addition reaction were tested, including activation of the nucleophile by inorganic base in a biphasic aqueous system, thermal activation, and ball-milling. Hydrogen-bonding catalysis was effective in all these methods, providing 1,4-addition products in high yields and stereoselectivities of up to 98% requiring 1-5 mol% of Cinchona alkaloid squaramide.

Advanced Synthesis & Catalysis published new progress about Alcohols, propargyl Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Hor, Papan Kumar; Goswami, Debabrata; Ghosh, Kuntal; Tako, Miklos; Halder, Suman Kumar; Mondal, Keshab Chandra published the artcile< Preparation of rice fermented food using root of Asparagus racemosus as herbal starter and assessment of its nutrient profile>, HPLC of Formula: 112-63-0, the main research area is rice fermented food Asparagus root herbal starter nutrient profile.

The popularity of traditional fermented food products is based on their healthiness. The addition of a starter brings consistent, desirable, and predictable food changes with improved nutritive, functional, and sensory qualities. The addition of a mixture of plant residues as a starter or source of microbes is an age-old practice to prepare traditional fermented food and beverages, and most of the reported data on traditional foods were based on the anal. of the final product. The contribution of an individual starter component (plant residue) is not exptl. substantiated for any traditional fermented food, but this data are very essential for the formulation of an effective starter. In this study, Asparagus racemosus, which used as a common ingredient of starter for preparation of rice fermented food in the Indian sub-continent, was used as a starter for the preparation of rice fermented food under laboratory scale, and its microbial and nutrient profile was evaluated. The fermented product was a good source of lactic acid bacteria, Bifidobacterium sp., yeast, etc. The food product was acidic and enriched with lactic acid and acetic acid with titratable acidity of 0.65%. The content of protein, fat, minerals, and vitamins (water-soluble) was considerably improved. Most notably, oligosaccharide (G3-matotriose), unsaturated fatty acids (ω3, ω6, ω7, and ω9), and a pool of essential and non-essential amino acids were enriched in the newly formulated food. Thus, the herbal starter-based rice fermented food would provide important macro- and micronutrients. They could also deliver large numbers of active microorganisms for the sustainability of health. Therefore, the selected plant part conferred its suitability as an effective starter for the preparation of healthier rice-based food products.

Systems Microbiology and Biomanufacturing published new progress about Batch fermentation. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, HPLC of Formula: 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Guo, Tao; Ding, Yalan; Zhou, Lili; Xu, Haiyan; Loh, Teck-Peng; Wu, Xiaojin published the artcile< Palladium-Catalyzed anti-Michael Reductive Heck Reaction of α,β-Unsaturated Esters>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is palladium catalyzed anti Michael reductive Heck unsaturated ester.

A general intermol. anti-Michael reductive Heck reaction of α,β-unsaturated esters with organobromides has been developed. Most topical classes of aryl, heteroaryl, and vinyl bromides were found to efficiently react with a variety of internal conjugated alkenes. This protocol set up a platform toward diverse α-arylated 1,6-dicarbonyl frameworks found in natural products and drugs, which are still highly challenging targets in traditional α-arylation protocols because of competitive selectivity of enolation. A removable directing group, gram-scale reaction, and modification of complex mols. have addnl. demonstrated that the anti-Michael reductive Heck reaction is a powerful complementary strategy to the classical α-arylation approaches. Preliminary mechanistic studies are consistent with our proposed mechanistic design.

ACS Catalysis published new progress about Aryl bromides Role: RCT (Reactant), RACT (Reactant or Reagent). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ohanessian, Jacqueline; Caron, Michel published the artcile< A spectrophotometric study of the carbohydrate binding site of peanut lectin>, Application In Synthesis of 112-63-0, the main research area is peanut lectin carbohydrate binding; structure activity carbohydrate binding lectin.

The difference spectra spectrophotometric method (spectra recorded between 260 and 300 nm, determined at 10°) was used to determine the binding constants for specific binding of sugars (16 mono-and oligosaccharides) to peanut lectin. For C(6), an extracyclic chain is needed for lectin interaction, and orientation of the -OH group on C(6) is essential; substitution of the hydroxymethyl group decreases the strength of the association A free axial -OH on C(4) is needed for binding. A C(2) equatorial hydroxyl group is not essential for interaction, but the axial position of this group decreases the binding. Methylation of C(1) favors association; there seems to be a slight preference for the α-anomer configuration. For the glycosidic bonds, compounds with the β(1→4) linkage bind more strongly to the lectin than those with the α(1→6) linkage. Overall, these results show that the sequence C(4)-O(4), C(5), C(6)-O(6) of the galactopyranosyl ring is involved in the interactions in the carbohydrate binding site of peanut lectin as postulated previously (Lotan, R., et al, 1975), and that for di- and oligosaccharides, it appears that the configuration of C(1), the nature of the osidic bond and of the 2nd residue may influence the strength of the association

Lectins: Biology, Biochemistry, Clinical Biochemistry published new progress about Agglutinins and Lectins Role: BIOL (Biological Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Abdel Karim, M.; Sima, A.; Mekki, Mai published the artcile< Chemical constituents and antimicrobial activity of sudanese lagenaria siceraria standley (Cucurbitaceae) Oil>, Application In Synthesis of 112-63-0, the main research area is Cucurbitaceae oil sudanese lagenaria siceraria standley antimicrobial activity.

In this study, the constituents and antimicrobial activity of Lagenaria siceraria oil. have been investigated. Lagenaria sicerariaStandley is a common fruit vegetable in the family Cucurbitaceae. The fruit has many uses in ethnomedicine. Fruit is used as diuretic, immunosuppressant, cardio-protective and cardio-tonic. Lagenaria siceraria possesses antioxidant, hypolipidemic and hepatoprotective properties. GC- MS anal. of Lagenaria siceraria oil revealed the presence of three major constituents: linoleic acid Et ester (57.96%); 9,12-octadecenoic acid Me ester (19.56%) and hexdecanoic acid (10.15%%). The oil was screened for antimicrobial activity against five standard human pathogens by using the paper disk diffusion method. The oil showed moderate activity against Pseudomonas aeruginosa.

Pharmaceutical and Chemical Journal published new progress about Acetoxymethyl esters Role: BSU (Biological Study, Unclassified), BIOL (Biological Study). 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Dai, Weimin; Wu, An; Li, Yunping; Yu, Guofeng; Yan, Xinjiang published the artcile< XPA Enhances Temozolomide Resistance of Glioblastoma Cells by Promoting Nucleotide Excision Repair.>, Application In Synthesis of 112-63-0, the main research area is XPA; glioblastoma; nucleotide excision repair; temozolomide.

Glioblastoma is the most frequent, as well as aggressive kind of high-grade malignant glioma. Chemoresistance is posing a significant clinical barrier to the efficacy of temozolomide-based glioblastoma treatment. By suppressing xeroderma pigmentosum group A (XPA), a pivotal DNA damage recognition protein implicated in nucleotide excision repair (NER), we devised a novel method to enhance glioblastoma therapy and alleviate temozolomide resistance. On the basis of preliminary assessment, we found that XPA dramatically increased in glioblastoma compared with normal cells and contributed to temozolomide resistance. By constructing XPA stably knockdown cells, we illustrate that XPA protects glioma cells from temozolomide-triggered reproductive cell death, apoptosis, as well as DNA repair. Besides, XPA silencing remarkably enhances temozolomide efficacy in vivo. This study revealed a crucial function of XPA-dependent NER in the resistance of glioma cells to temozolomide.

Cell transplantation published new progress about 112-63-0. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application In Synthesis of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics