Tag: M.W=250-300

Kim, Hyun-Joong published the artcileStudy of UV-initiated polymerization and UV crosslinking of acrylic monomers mixture for the production of solvent-free pressure-sensitive adhesive films, Category: esters-buliding-blocks, the publication is Polymer Testing (2022), 107424, database is CAplus.

UV-polymerizable and UV-crosslinkable pressure-sensitive adhesive acrylic compositions are widely applied for high-quality carrier-free films, one-sided or double-sided self-adhesive tapes. Comprehensive studies of the properties of novel acrylic PSAs for carrier-free films or adhesive tapes were carried out. Solvent-free acrylic pressure-sensitive adhesive layers were UV-crosslinked using various photoreactive crosslinking agents. Polymer content during UV-polymerization, prepolymers viscosity, temperature changes of prepolymer during UV-initiated polymerization process were investigated. The chem. structure of prepolymer and polymerized acrylic film were examined using FTIR spectroscopy. Prepolymer mixtures were transferred on the transparent carriers to form 1 mm thick polymer films, and then UV-crosslinked after the addition of the selected acrylic crosslinker. Final adhesive films were then tested to evaluate their functional properties as the tack, peel adhesion, and shear strength at 20 °C and 70 °C. From the results reveal that both concentrations of acrylic acid in the prepolymer, and crosslinking agent in the final polymer layer, have a significant influence on the functional properties of the produced PSA films.

Polymer Testing published new progress about 15625-89-5. 15625-89-5 belongs to esters-buliding-blocks, auxiliary class Polymerization Reagents,Crosslinkers, name is Trimethylolpropane triacrylate, and the molecular formula is C15H20O6, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Heerding, Dirk A. published the artcileNew Benzylidenethiazolidinediones as Antibacterial Agents, Quality Control of 115314-17-5, the publication is Bioorganic & Medicinal Chemistry Letters (2003), 13(21), 3771-3773, database is CAplus and MEDLINE.

A novel benzylidenethiazolidinedione has been discovered with antimicrobial activity. Here, we present the results of a structure-activity study on this compound with respect to its antimicrobial activity.

Bioorganic & Medicinal Chemistry Letters published new progress about 115314-17-5. 115314-17-5 belongs to esters-buliding-blocks, auxiliary class Epoxides,Chiral,Nitro Compound,Sulfonate,Benzene, name is (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, and the molecular formula is C9H9NO6S, Quality Control of 115314-17-5.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Rai, Kamal published the artcileEnhanced anticoagulant activity of hirudin-i analogue co-expressed with arylsulfotransferase in periplasm of E. coli BL21(DE3), Quality Control of 6217-68-1, the publication is Journal of Biotechnology (2020), 107-112, database is CAplus and MEDLINE.

Hirudin, a blood anticoagulant, is the most potent natural thrombin inhibitor of leech origin. Its application is limited because it is difficult to obtain abundant natural hirudin directly from the leech. Although some bioengineering methods can significantly increase the production of hirudin, the reduced efficacy of recombinant hirudin (rH) remains a critical shortcoming. The lack of sulfation of tyrosine 63 in rH is an important cause of its inadequate performance. This article is the first report of periplasmic co-expression of an rH-I analog with arylsulfotransferase (ASST) in E. coli BL21(DE3). Co-expressed rH-I analog with sulfate donor substrate (p-nitrophenyl sulfate potassium) showed anticoagulant (rabbit and goat serum) activity twice more than rH-I analog expressed without ASST, indicating its potential periplasmic sulfation. Moreover, purified rH-I analog showed above 4.5 times higher anticoagulant activity compared to therapeutic anti-thrombotic heparin (HE). At the same time, pH-dependent differential solubility was employed to purify rH analogs from fermentation broth, which is a simple, fast and inexpensive purification technol., and can potentially be used for larger scale purification This will also greatly improve the application of rH in clin. treatment.

Journal of Biotechnology published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Quality Control of 6217-68-1.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Fitzgerald, J. W. published the artcileThe occurrence of an inducible arylsulfatase in Comamonas terrigena, Name: Potassium 4-nitrophenyl sulfate, the publication is FEMS Microbiology Letters (1977), 2(4), 221-4, database is CAplus.

When C. terrigena was cultured in a synthetic mineral medium containing p-nitrophenyl sulfate (NPS) as S source, growth occurred after a 35-h lag and was accompanied by the increased ability of cell extracts to hydrolyze NPS and by the release from intact cells of p-nitrophenol. A S-mediated derepression mechanism for the pos. control of arylsulfatase is apparently absent in C. terrigena since the cells exhibited low activity after growth without added S or in the presence of Na₂SO₄ or methionine. NPS produced ∼2000-fold increase in arylsulfatase activity, indicating that the enzyme is substrate-inducible. NPS was the most effective inducer and substrate for arylsulfatase compared with p-nitrocatechol sulfate, p-acetylphenyl sulfate, and L-tyrosine-O-sulfate.

FEMS Microbiology Letters published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Name: Potassium 4-nitrophenyl sulfate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ding, Chao published the artcileComputer-Aided Formulation of Magnetic Pastes for Composition Improvement for Power Magnetics, Synthetic Route of 15625-89-5, the publication is IEEE Transactions on Magnetics (2022), 58(5), 2000608, database is CAplus.

The size of magnetic components can be reduced with novel designs, but the intricate structures are difficult to make due to the limited sets of conventional magnetic core geometries and materials. Magnetic pastes have the flexibility of forming complicated structures with a pressure-less and low-temperature molding process, and are ideal for making the novel magnetic designs. The conventional approach of developing magnetic pastes involves time-consuming exptl. iterations to determine the optimal composition parameters. Instead of relying on the trial-and-error efforts, we explored a computer-aided approach to guiding the magnetic paste development by creating material’s microstructure by discrete element method (DEM) and studying the property by finite element method (FEM). From a starting formula with two different-sized spherical powders, we improved the composition guided by DEM and FEM, and studied the magnetic permeability vs. two variables: powder mixing ratio and magnetic volume fraction. The simulated permeability agreed well with the exptl. data with an average error of only 10%. With the computeraided formulation methodol. demonstrated in this work, one can develop magnetic pastes with min. exptl. efforts and explore different compositions to meet various magnetic design needs.Index Terms-Computer-aided formulation, discrete element method (DEM), finite element method (FEM), magnetic pastes.

IEEE Transactions on Magnetics published new progress about 15625-89-5. 15625-89-5 belongs to esters-buliding-blocks, auxiliary class Polymerization Reagents,Crosslinkers, name is Trimethylolpropane triacrylate, and the molecular formula is C15H20O6, Synthetic Route of 15625-89-5.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Garcia-Rubino, M. E. published the artcileEnantiospecific Synthesis of Heterocycles Linked to Purines: Different Apoptosis Modulation of Enantiomers in Breast Cancer Cells, Safety of (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, the publication is Current Medicinal Chemistry (2013), 20(38), 4924-4934, database is CAplus and MEDLINE.

The issue of chiral drug is now a major theme in the design, discovery and development of new drugs. It has been shown for many pharmaceuticals that only one enantiomer contains the desired activity, and the synthesis of such drug mols. in their optically pure form is becoming increasingly important. Mitsunobu reaction was carried out between (R)- and (S)-3,4-dihydro-2H-1,5-benzoxathiepin-3-ol and purines under microwave irradiation A contraction into a six-membered ring takes place with concomitant inversion at the stereocentre with excellent enantiomeric excesses giving rise to the homochiral 9-(2,3-dihydro-1,4-benzoxathiin-3-ylmethyl)-9H-purines. The anti-tumor activity of all enantiomers is reported against the caspase-3-deficient MCF-7 and the wild type SKBR-3 human breast cancer cells. The most active homochiral compound displays an IC₅₀ of 1.85 μM and induces inhibition of the translation initiation factor eIF2α. All homochiral compounds included in this study show different apoptotic effects between both enantiomers with levels up to 99%. We have analyzed caspase-mediated apoptotic pathways on enantiomers and racemates. We have found a homochiral derivative that activates the canonical intrinsic caspase-8/caspase-3 apoptotic pathway on the MCF-7 cells, and a racemic compound that induces caspase-2 activation. Moreover, we demonstrate the involvement of caspase activation during cell death induced by these compounds in SKBR-3 cells.

Current Medicinal Chemistry published new progress about 115314-17-5. 115314-17-5 belongs to esters-buliding-blocks, auxiliary class Epoxides,Chiral,Nitro Compound,Sulfonate,Benzene, name is (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, and the molecular formula is C9H9NO6S, Safety of (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Baker, Jennifer R. published the artcileAmino Alcohols as Potential Antibiotic and Antifungal Leads, Application of (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, the publication is Molecules (2022), 27(7), 2050, database is CAplus and MEDLINE.

Five focused compound libraries based on prior studies of the author. were synthesized and screened for antibiotic and anti-fungal activity against S. aureus, E. coli, K. pneumoniae, P. aeruginosa, A. baumannii, C. albicans and C. neoformans. Low levels of activity, at the initial screening concentration of 32μg/mL, were noted with analogs of (Z)-2-(3,4-dichlorophenyl)-3-phenylacrylonitriles which made up the first two focused libraries produced. Modifications of the terminal aromatic moiety were explored through epoxide installation by flow chem. mediated ring opening aminolysis with discreet sets of amines to the three new focused libraries of afforded amino alcs. Three new focused libraries were developed from substituted anilines, cyclic amines, and Ph linked heterocyclic amines. The aniline-based compounds were inactive against the bacterial and fungal lines screened but the introduction of piperidine, piperazine, or morpholine, showed >50% inhibition when evaluated at 32μg/mL compound concentration against methicillin-resistant Staphylococcus aureus. Aromatic substituted piperidine or piperazine switched library activity from antibacterial to anti-fungal activity with compounds containing (4-methylpiperazin-1-yl),(4-hydroxyphenylpiperazin-1-yl) and (4-cyclohexylpiperazin-1-yl) showing >95% inhibition of Cryptococcus neoformans var. grubii H99 growth at 32μg/mL, while few acrylonitriles showed 32μg/mL against Staphylococcus aureus.

Molecules published new progress about 115314-17-5. 115314-17-5 belongs to esters-buliding-blocks, auxiliary class Epoxides,Chiral,Nitro Compound,Sulfonate,Benzene, name is (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, and the molecular formula is C9H9NO6S, Application of (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Huang, Yugang published the artcileBis(trimethylsilyl)amino modified Type II photoinitiators can alleviate oxygen inhibition of near-UV LED photopolymerization due to moisture induced decomposition of initiators, COA of Formula: C15H20O6, the publication is European Polymer Journal (2022), 111236, database is CAplus.

Near UV-LED photopolymerization of acrylates can find many crucial applications in industrial fields, such as coatings, adhesives and 3D printing of hydrogels. However, developing the photoinitiators (PIs) well matching with the com. LED light sources and reducing oxygen inhibition effect remain challenges. Herein, we have synthesized three kinds of type II PIs containing bis(trimethylsilyl)amino groups; Molar extinction coefficients of these PIs are all at the 10³ ∼ 10⁴ (L·mol^-1·cm^-1) order of magnitude at the 365 ∼ 395 nm, comparable to the com. PIs including Michler’s ketone (MK) and 2-isopropylthioxanthone (ITX); However, their photoinitiation capacity is much better than the MK and the ITX. In addition, these PIs have better resistance to the oxygen inhibition effect than the MK. Some researchers think the PIs containing rich Si/F elements can self-migrate towards upper layers of curing systems to reduce the oxygen inhibition effect, however, these obtained PIs with high Si fraction did not have such effect. Based on the obtained exptl. results, we have proposed a new mechanism explaining their good ability to reduce the oxygen inhibition: The moisture induced decomposition of the initiators can play a key role in alleviating the oxygen inhibition; The generated Si-containing fragments after PIs’ hydrolysis can self-float towards the top surfaces to hinder the oxygen penetration, not the self-floating effect of the PIs by themselves.

European Polymer Journal published new progress about 15625-89-5. 15625-89-5 belongs to esters-buliding-blocks, auxiliary class Polymerization Reagents,Crosslinkers, name is Trimethylolpropane triacrylate, and the molecular formula is C15H20O6, COA of Formula: C15H20O6.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Chan, Kai-Hsiang published the artcileLong-period fiber gratings based on blue phase liquid crystal/polymer composites, Name: Trimethylolpropane triacrylate, the publication is Liquid Crystals (2022), 49(1), 50-58, database is CAplus.

A relatively simple and cost-effective method to realize a novel long-period fiber grating (LPFG) based on blue phase liquid crystal (BPLC) composites was proposed and exptl. demonstrated by implementing photopolymerization-induced phase separation (PIPS) through a binary photomask. The BPLC-polymer composite zones were obtained by a process of periodic UV light with phase separation of the BPLC mols. and UV-curable monomer mixture The appearance and optical characteristics of the proposed LPFGs have been studied exptl. Exptl. results show that optimum PIPS process conditions are critical for achieving a reliable LPFG-based fiber device. Compared with the previously reported methods, this new technique for designing and making an LPFG is more cost-effective and highly flexible due to the ease in manufacturing of the grating composite structure in the all-fiber system, which can provide great potential for photonic applications.

Liquid Crystals published new progress about 15625-89-5. 15625-89-5 belongs to esters-buliding-blocks, auxiliary class Polymerization Reagents,Crosslinkers, name is Trimethylolpropane triacrylate, and the molecular formula is C15H20O6, Name: Trimethylolpropane triacrylate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Meng, Jiali published the artcileCrown fit and dimensional accuracy of zirconia fixed crowns based on the digital light processing technology, Quality Control of 15625-89-5, the publication is Ceramics International (2022), 48(12), 17852-17863, database is CAplus.

Zirconia is extensively used for manufacturing dental prostheses because of its superior mech. properties. The idea of using 3D printing to manufacture zirconia dental prostheses has gradually become popular, but printing accurate shapes and obtaining excellent dimensional accuracy still remain challenging. In this study, the optimal curing parameters and shrinkage ratios of zirconia slurry were investigated using a multi-angle model and a standard fixed crown model. Then the dimensional accuracy and crown fit were investigated, and the fixed crown and fixed bridge were fabricated by using digital light processing (DLP) technol. Further, the dimensional accuracy and crown fit were investigated. The results showed that the optimal curing parameters and enlargement factors for zirconia fixed crown printing were 80 PWM (light source power), 2s (curing time) and 1.400, 1.400, 1.500 (in X, Y, Z directions), resp. The internal fit was 239.3 ± 7.9 μm, which met the clin. criteria (≤300 μm), whereas the marginal fit was 128.1 ± 7.1 μm, which was extremely close to the clin. criteria (≤120 μm). For dimensional accuracy, the standard error of sintered fixed crown was 0.14 ± 0.06 mm, and the boundary dimensional accuracy and anatomical landmark points′ dimensional accuracy were also investigated. In addition, the d. of sintered zirconia was 6.01 ± 0.02 g/cm³. From the results of this study, it could be found that the crown fit of zirconia fixed crowns printed using the DLP technique could be close to clin. standards, although there is still a gap with the zirconia fixed crowns from the milling technique. In addition incomplete removal of the support structures have a neg. impact on dimensional accuracy, hence it is necessary to further explore the optimization strategies of the support structures for improving the dimensional accuracy of fixed crowns printed by DLP.

Ceramics International published new progress about 15625-89-5. 15625-89-5 belongs to esters-buliding-blocks, auxiliary class Polymerization Reagents,Crosslinkers, name is Trimethylolpropane triacrylate, and the molecular formula is C15H20O6, Quality Control of 15625-89-5.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics