Tag: M.W=250-300

Tang, Zhaoxian published the artcileCinnamoylformate derivatives photoinitiators with excellent photobleaching ability and cytocompatibility for visible LED photopolymerization, Formula: C15H20O6, the publication is Progress in Organic Coatings (2022), 106969, database is CAplus.

In this work, four Et cinnamoylformate derivatives photoinitiators (ECFs), which have good photobleaching ability and excellent cytocompatibility in LED-triggered photopolymerization, were designed and synthesized by a simple two-step reaction. The potential initiating and photobleaching mechanisms of ECFs under visible LED were researched by UV-visible absorption spectroscopy, NMR, high-resolution mass spectroscopy and ESR. The as-prepared photoinitiators Et p-methoxycinnamoyl formate (O-ECF) and Et p-methylmercaptocinnamoyl formate (S-ECF) exhibited much higher initiating rate under 405 nm and 455 nm LED compared to the com. photoinitiator 2-isopropylthioxanthone (ITX). More significantly, carbon-carbon double bonds of ECFs can polymerize in the presence of tertiary amine under the irradiation of 455 nm or 405 nm LED, which endows ECFs with good photobleaching performance and excellent migration stability and cytocompatibility. Furthermore, ECFs are able to greatly initiate deep-layer photopolymerization under 455 nm LED and the photopolymerization depth reached 7.0 cm after the irradiation for 20 min. This work also affords a new perspective for designing photoinitiators with good photobleaching performance.

Progress in Organic Coatings published new progress about 15625-89-5. 15625-89-5 belongs to esters-buliding-blocks, auxiliary class Polymerization Reagents,Crosslinkers, name is Trimethylolpropane triacrylate, and the molecular formula is C8H5F3O2S, Formula: C15H20O6.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Suvarli, Narmin published the artcileSynthesis of Spherical Nanoparticle Hybrids via Aerosol Thiol-Ene Photopolymerization and Their Bioconjugation, Product Details of C15H20O6, the publication is Nanomaterials (2022), 12(3), 577, database is CAplus and MEDLINE.

Hybrid nanomaterials possess the properties of both organic and inorganic components and find applications in various fields of research and technol. In this study, aerosol photopolymerization is used in combination with thiol-ene chem. to produce silver poly(thio-ether) hybrid nanospheres. In aerosol photopolymerization, a spray solution of monomers is atomized, forming a droplet aerosol, which then polymerizes, producing spherical polymer nanoparticles. To produce silver poly(thio-ether) hybrids, silver nanoparticles were introduced to the spray solution Diverse methods of stabilization were used to produce stable dispersions of silver nanoparticles to prevent their agglomeration before the photopolymerization process. Successfully stabilized silver nanoparticle dispersion in the spray solution subsequently formed nanocomposites with non-agglomerated silver nanoparticles inside the polymer matrix. Nanocomposite particles were analyzed via scanning and transmission electron microscopy to study the degree of agglomeration of silver nanoparticles and their location inside the polymer spheres. The nanoparticle hybrids were then introduced onto various biofunctionalization reactions. A two-step bioconjugation process was developed involving the hybrid nanoparticles: (1) conjugation of (biotin)-maleimide to thiol-groups on the polymer network of the hybrids, and (2) biotin-streptavidin binding. The biofunctionalization with gold-nanoparticle-conjugates was carried out to confirm the reactivity of -SH groups on each conjugation step. Fluorescence-labeled biomols. were conjugated to the spherical nanoparticle hybrids (applying the two-step bioconjugation process) verified by Fluorescence Spectroscopy and Fluorescence Microscopy. The presented research offers an effective method of synthesis of smart systems that can further be used in biosensors and various other biomedical applications.

Nanomaterials published new progress about 15625-89-5. 15625-89-5 belongs to esters-buliding-blocks, auxiliary class Polymerization Reagents,Crosslinkers, name is Trimethylolpropane triacrylate, and the molecular formula is C22H12F6O6S2, Product Details of C15H20O6.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Chiummiento, Lucia published the artcileSynthesis and biological evaluation of novel small non-peptidic HIV-1 PIs: The benzothiophene ring as an effective moiety, HPLC of Formula: 115314-17-5, the publication is Bioorganic & Medicinal Chemistry Letters (2012), 22(8), 2948-2950, database is CAplus and MEDLINE.

Synthesis and biol. evaluation of a new series of potential HIV-1 protease inhibitors incorporating different heterocycles are described. The variation of heteroatom in such mols. has displayed totally different biol. activities and a benzothiophene containing inhibitor has shown high potency against wild type HIV-1 protease with IC₅₀ = 60 nM, thanks to the lower desolvation penalty to be payed by such hydrophobic moiety.

Bioorganic & Medicinal Chemistry Letters published new progress about 115314-17-5. 115314-17-5 belongs to esters-buliding-blocks, auxiliary class Epoxides,Chiral,Nitro Compound,Sulfonate,Benzene, name is (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, and the molecular formula is C9H9NO6S, HPLC of Formula: 115314-17-5.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Chiummiento, Lucia published the artcileNew indolic non-peptidic HIV protease inhibitors from (S)-glycidol: synthesis and preliminary biological activity, Safety of (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, the publication is Tetrahedron (2009), 65(31), 5984-5989, database is CAplus.

A series of non-peptidic HIV protease inhibitors, e.g., I, were synthesized starting from the same optically active precursor, (S)-glycidol. The substrate was easily converted into different indolic sulfonamides or amines by regioselective reactions. The preliminary inhibitory activity was evaluated.

Tetrahedron published new progress about 115314-17-5. 115314-17-5 belongs to esters-buliding-blocks, auxiliary class Epoxides,Chiral,Nitro Compound,Sulfonate,Benzene, name is (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, and the molecular formula is C9H9NO6S, Safety of (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

George, J. Richard published the artcileTyramine-mediated enhancement of arylsulfatase purified from Pseudomonas C₁₂B, Quality Control of 6217-68-1, the publication is Biochemical Society Transactions (1979), 7(5), 1082-3, database is CAplus and MEDLINE.

The K_m and V_max of arylsulfatase, purified to homogeneity from Pseudomonas C₁₂B, acting on the K salt of p-nitrophenyl sulfate (I) alone were 2.34 × 10^-5M and 5.5 × 10^-3 μmol/min, resp. As the ratio of tryptamine in the assay mixture was increased, the K_m and V_max were increased until values of 8.00 × 10^-5M and 8.52 × 10^-3 μmol/min were obtained. Arylsulfatase had less affinity, therefore, for the tryptamine salt than for the K salt of I, but hydrolyzed the tryptamine salt at a faster rate. At a tryptamine/I ratio of 5:1, the V_max was 1.54-fold greater than that obtained with I alone. Phenylamines appear, therefore, to activate the activity in vitro of arylsulfatase from Pseudomonas by forming a salt with the substrate, which weakens the O-S bond of the sulfate ester, allowing it to be more rapidly hydrolyzed by the enzyme.

Biochemical Society Transactions published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Quality Control of 6217-68-1.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

George, James R. published the artcileStimulation of bacterial arylsulfatase activity by arylamines: evidence for substrate activation, Name: Potassium 4-nitrophenyl sulfate, the publication is Journal of Bacteriology (1981), 147(1), 69-74, database is CAplus and MEDLINE.

A number of arylamines (including tyramine and tryptamine) increased the in vitro activity of arylsulfatase from Pseudomonas species strain C₁₂B. Amino acid analogs of these amines (e.g., tyrosine and tryptophan) failed to exert an effect. Stimulation of activity by tyramine could not be accounted for in terms of sulfotransferase activity for this phenol and no shift in the pH optimum for the enzyme occurred in the presence of tryptamine. Increased V_max due to these amines was independent of enzyme concentration but varied significantly with substrate concentration Evidence is presented which suggests that arylamines enhance arylsulfatase activity by forming a salt linkage with the substrate and rendering it more susceptible to enzymic and acid-catalyzed hydrolysis. The recrystallized tryptamine salt of the substrate exhibited a reduced affinity for the enzyme but was hydrolyzed more rapidly than the K salt, which is normally employed as the assay substrate.

Journal of Bacteriology published new progress about 6217-68-1. 6217-68-1 belongs to esters-buliding-blocks, auxiliary class Salt,Nitro Compound,Sulfonate,Benzene, name is Potassium 4-nitrophenyl sulfate, and the molecular formula is C6H4KNO6S, Name: Potassium 4-nitrophenyl sulfate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Adam, Jean-Michel published the artcileDevelopment of a Scalable Synthesis of (S)-3-Fluoromethyl-γ-butyrolactone, Building Block for Carmegliptin’s Lactam Moiety, Quality Control of 115314-17-5, the publication is Organic Process Research & Development (2011), 15(3), 515-526, database is CAplus.

Several new routes are reported for the synthesis of (S)-3-fluoromethyl-γ-butyrolactone. An asym. hydrogenation-based synthesis was chosen as the enabling route to produce the lactone on a 10-kg scale. A superior stereoselective route starting from (S)-tert-Bu glycidyl ether which afforded the desired lactone in three steps with ∼50% overall yield was finally selected for further development and production

Organic Process Research & Development published new progress about 115314-17-5. 115314-17-5 belongs to esters-buliding-blocks, auxiliary class Epoxides,Chiral,Nitro Compound,Sulfonate,Benzene, name is (R)-Oxiran-2-ylmethyl 3-nitrobenzenesulfonate, and the molecular formula is C9H9NO6S, Quality Control of 115314-17-5.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Teyssandier, Joan published the artcilePolydiacetylene photocomposite material obtained by orthogonal chemistry: a detailed study at the mesoscopic scale, Formula: C15H20O6, the publication is Materials Advances (2022), 3(5), 2558-2567, database is CAplus.

A recent paper reported the spatially controlled photopolymerization and subsequent 3D printing of polydiacetylene (PDA) by orthogonal chem. using dual-wavelength polymerization Diacetylene monomers were dispersed in an acrylate resin to form a photocomposite in a two-step process: a first irradiation photopolymerizes the acrylate freezing the diacetylene monomers which were polymerized in a second step at a different wavelength. In the present article, for a better understanding of the organization of the generated functional composites, this process is studied at the mesoscopic scale by performing optical and SEM combined with correlative Raman, AFM and cathodoluminescence measurements. We have diluted the PCDA/acrylate blend in dichloromethane (CH₂Cl₂) and performed drop casting deposition on graphite. We discovered that the acrylate-diacetylene mixture promotes dramatically the formation of large PDA crystals. The confinement of PDA crystals inside the polyacrylate hindered their thermochromic blue-to-red transition, as revealed by correlative Raman microscopy. Cathodoluminescence measurements on the photocomposite have also shown that the light emission properties of PDAs are strongly modified by the induced confinement.

Materials Advances published new progress about 15625-89-5. 15625-89-5 belongs to esters-buliding-blocks, auxiliary class Polymerization Reagents,Crosslinkers, name is Trimethylolpropane triacrylate, and the molecular formula is C5H11NO2S, Formula: C15H20O6.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Gencoglu, Turkan published the artcileA Water Soluble, Low Migration, and Visible Light Photoinitiator by Thioxanthone-Functionalization of Poly(ethylene glycol)-Containing Poly(β-amino ester), Safety of Trimethylolpropane triacrylate, the publication is Macromolecular Chemistry and Physics (2022), 223(13), 2100450, database is CAplus.

A novel photoinitiator (PI) is described here for low ecol. impact, p(PEGDA575-TX): It is water soluble, polymerizable, thioxanthone (TX) functional, and is a one-component poly(ethylene glycol)-based poly(β-amino ester). The PI is synthesized in one step via classical aza-Michael addition reaction between poly(ethylene glycol) diacrylate (Mn = 575 D) and amine functionalized TX (2-(2-aminoethoxy)-9H-thioxanthen-9-one). It absorbs at ≈ 404 nm (ε = 14 000-44 309) in water and can photodecompose with or without additives such as Et 4-(dimethylamino)benzoate (EDB) and bis-(4-tert-butylphenyl)-iodonium hexafluorophosphate (Iod). Although it is an effective one-component visible light PI for free radical polymerization of di- and tri(meth)acrylates, EDB or Iod will be favorable for synergistic effect. p(PEGDA575-TX) has higher initiating reactivity, reducing ability of oxygen inhibition and migration stability compared to TX, which make it environmental friendly.

Macromolecular Chemistry and Physics published new progress about 15625-89-5. 15625-89-5 belongs to esters-buliding-blocks, auxiliary class Polymerization Reagents,Crosslinkers, name is Trimethylolpropane triacrylate, and the molecular formula is C15H20O6, Safety of Trimethylolpropane triacrylate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Launay, Valentin published the artcileSafe near infrared light for fast polymers surface sterilization using organic heaters, Product Details of C15H20O6, the publication is Materials Chemistry Frontiers (2022), 6(9), 1172-1179, database is CAplus.

Sterilization approaches using UV radiation (e.g. 254 nm), dry heat and moist heat have been widely reported in the literature. A breakthrough approach is presented here. In the present study, we proposed a most environmentally friendly approach for polymer surface sterilization using safe Near-IR (NIR) light to produce a powerful photothermal effect using organic NIR dyes as heaters. Markedly, well selected organic dyes strongly absorbing in the NIR range have been used as stimuli responsive compounds When excited upon NIR light, these heaters release the light energy to their surrounding environment in the form of heat. In this work, trimethylolpropane triacrylate (TMPTA) based polymers, used as benchmark materials for polymers or coatings, could reach high temperatures (>120°C) in a very short time scale (∼30 s). Using heater-containing polymers, sterilization experiments showed very good results with total eradication of bacteria (Escherichia coli) after only 2 min of NIR irradiation (2.55 W cm^-2). These results suggest that short irradiation flashes could be enough to sterilize contaminated surfaces. Moreover, irradiation tests have been performed on three NIR heaters in the NIR-II range (1000-1700 nm) for a better in-depth penetration. Indeed, almost 200°C could be reached by polymers in less than 1 min of NIR irradiation (2.5 W cm^-2). Therefore, NIR LED irradiation of heater-containing polymers constitutes here a robust, transportable and safe sterilization method.

Materials Chemistry Frontiers published new progress about 15625-89-5. 15625-89-5 belongs to esters-buliding-blocks, auxiliary class Polymerization Reagents,Crosslinkers, name is Trimethylolpropane triacrylate, and the molecular formula is C15H20O6, Product Details of C15H20O6.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics