Tag: M.W=250-300

Hiscock, Jennifer R.; Gale, Philip A.; Hynes, Michael J. published the artcile< Tris-(2-aminoethyl)amine-based tripodal trisindolylureas: new receptors for sulphate>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is anion receptor urea amine preparation phosphate sulfate acetate benzoate.

Several TREN-based amide or urea linked tris-indole anion receptors have been synthesized and their anion complexation properties studied in DMSO-d6/water mixtures

Supramolecular Chemistry published new progress about Amidation. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Alayande, Abayomi Babatunde; Hong, Seungkwan published the artcile< Ultraviolet light-activated peroxymonosulfate (UV/PMS) system for humic acid mineralization: Effects of ionic matrix and feasible application in seawater reverse osmosis desalination>, Reference of 112-63-0, the main research area is peroxymonosulfate humic acid mineralization seawater reverse osmosis desalination; Disinfection byproducts; Halides; Humic acid; Reactive halogen species; UV/PMS oxidation; Water treatment.

The use of membrane-based technol. has evolved into an important strategy for supplying freshwater from seawater and wastewater to overcome the problems of water scarcity around the world. However, the presence of natural organic matter (NOM), including humic substances affects the performance of the process. Here, we present a systematic report on the mineralization of humic acid (HA), as a model for NOM, in high concentration of salts using the UV light-activated peroxymonosulfate (UV/PMS) system as a potential alternative for HA elimination during membrane-based seawater desalination and water treatment processes. Effects of various parameters such as PMS concentration, solution type, pH, anions, and anion-cation matrix on HA mineralization were assessed. The results show that 100%, 78% and 58% of HA (2 mg/L TOC) were mineralized with rate constants of 0.085 min-1, 0.0073 min-1, and 0.0041 min-1 after 180 min reaction time at pH 7 when 0.5 mM PMS was used in deionized water, sodium chloride solution (35,000 ppm) and synthetic seawater, resp. The reduced efficiency under saline conditions was attributed to the presence of anions in the system that acted as sulfate and hydroxyl radicals scavengers. Furthermore, the safety of the treated synthetic seawater was evaluated by analyzing the residual transformed products. Overall, pretreatment with the UV/PMS system mitigated fouling on the RO membrane.

Environmental Pollution (Oxford, United Kingdom) published new progress about Fouling. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Beppu, Takaaki; Iwaya, Takeshi; Sato, Yuichi; Nomura, Jun-Ichi; Terasaki, Kazunori; Sasaki, Toshiaki; Yamada, Noriyuki; Fujiwara, Shunrou; Sugai, Tamotsu; Ogasawara, Kuniaki published the artcile< PET With 11C-Methyl-l-Methionine as a Predictor of Consequential Outcomes at the Time of Discontinuing Temozolomide-Adjuvant Chemotherapy in Patients With Residual IDH-Mutant Lower-Grade Glioma.>, Application of C19H34O2, the main research area is .

PURPOSE: The aim of this study was to clarify whether PET with 11C-methyl-l-methionine (11C-met PET) can predict consequential outcomes at the time of discontinuing temozolomide (TMZ)-adjuvant chemotherapy in patients with residual isocitrate dehydrogenase gene (IDH)-mutant lower-grade glioma. PATIENTS AND METHODS: Among 30 patients showing residual lesions of IDH-mutant lower-grade glioma, we compared the tumor-to-normal brain tissue ratio of standardized uptake values (SUVT/N) from 11C-met PET at the time of discontinuing TMZ-adjuvant chemotherapy with putative predictive factors including age, Karnofsky Performance Scale, number of courses of adjuvant therapy, residual tumor size, and promotor methylation status of O6-methylguanine-DNA methyl-transferase gene (MGMT). For each factor, progression-free survival (PFS) was compared between groups divided by cutoff values, determined to predict tumor relapse using receiver operating characteristic curves for each factor. Univariate and multivariate analyses were conducted using log-rank testing and Cox regression analysis, respectively. In addition, PFS was compared between patients grouped by combined findings from multiple predictors identified from univariate and multivariate analyses. RESULTS: Univariate and multivariate analyses identified SUVT/N from 11C-met PET and MGMT methylation status as independent predictors of outcomes after TMZ discontinuation. When comparing 3 groups assigned by the combination of MGMT and SUVT/N findings, PFS differed significantly among groups. CONCLUSIONS: The present study suggested that 11C-met PET at the time of discontinuing TMZ-adjuvant chemotherapy allows prediction of outcomes at least comparable to MGMT methylation status in patients with residual IDH-mutant lower-grade glioma. Further, 11C-met PET allows more precise prediction of outcomes by assessment in combination with MGMT findings.

Clinical nuclear medicine published new progress about 112-63-0. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Application of C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pan, Guihua; He, Changli; Chen, Min; Xiong, Qian; Cao, Weidi; Feng, Xiaoming published the artcile< Synthesis of dihydroisoquinoline and dihydropyridine derivatives via asymmetric dearomative three-component reaction>, Formula: C19H34O2, the main research area is dihydroisoquinoline dihydropyridine diastereoselective enantioselective; heteroarene allenoate methyleneindolinone asym dearomative three component reaction.

Authors report the first asym. three-component nucleophilic addition/dearomative [4+2] cycloaddition/isomerization cascade of transient dipoles generated from N-heteroarenes and allenoates with methyleneindolinones in the presence of chiral N,N’-dioxide/metal complexes. This tandem reaction enabled rapid access to versatile chiral polycyclic N-heterocycles with good to excellent enantioselectivities under mild reaction conditions in spite of the strong background reaction, including 1,2-dihydroisoquinoline, 1,2-dihydropyridine derivatives, and others. Meanwhile, a series of control experiments were conducted to elucidate the reaction mechanism and the roles of additives.

CCS Chemistry published new progress about [4+2] Cycloaddition reaction. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Becker, Jeffrey M.; Wilchek, Meir; Katchalski, Ephraim published the artcile< Irreversible inhibition of biotin transport in yeast by biotinyl-p-nitrophenyl ester>, Reference of 112-63-0, the main research area is biotin transport Saccharomyces inactivator; biotinylnitrophenyl yeast biotin transport.

Biotinyl-p-nitrophenyl ester (I) [33755-53-2] at .geq.10-7M irreversibly inactivated biotin [58-85-5] transport in Saccharomyces cerevisiae. The extent of inactivation increased with time, implying that I reacts with a transport component(s) to yield a covalently-bound biotinyl derivative I did not affect the transport of lysine [56-87-1], aspartic acid [56-84-8], or L-sorbose [87-79-6]. Inactivation of biotin transport by I was partially prevented in the presence of high concentrations of biotin (0.5mM). Biotinyl-p-nitroanilide [33755-54-3], (0.1mM) and acetyl-p-nitrophenyl ester (0.1mM) did not affect biotin transport when added to S. cerevisiae suspensions.

Proceedings of the National Academy of Sciences of the United States of America published new progress about Saccharomyces cerevisiae. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Reference of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ahadi, Somayeh; Awan, Shahid I.; Werz, Daniel B. published the artcile< Total Synthesis of Tri-, Hexa- and Heptasaccharidic Substructures of the O-Polysaccharide of Providencia rustigianii O34>, Recommanded Product: (2R,3R,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate, the main research area is synthon lipopolysaccharide Providencia rustigianii oligosaccharide preparation galactosamine coupling; oligosaccharide aminoglycoside preparation Providencia rustigianii polysaccharide coupling Birch; Providencia rustigianii; fucose; glycosylation; lipopolysaccharide (LPS); oligosaccharides.

A general and efficient strategy for synthesis of tri-, hexa- and heptasaccharidic substructures of the lipopolysaccharide of Providencia rustigianii O34 is described. For the heptasaccharide seven different building blocks were employed. Special features of the structures are an α-linked galactosamine and the two embedded α-fucose units, which are either branched at positions-3 and -4 or further linked at their 2-position. Convergent strategies focused on [4+3], [3+4], and [4+2+1] coupling. Whereas the [4+3] and [3+4] coupling strategies failed the [4+2+1] strategy was successful. As monosaccharidic building blocks trichloroacetimidates and phosphates were employed. Global deprotection of the fully protected structures was achieved by Birch reaction.

Chemistry – A European Journal published new progress about Aminoglycosides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 4098-06-0 belongs to class esters-buliding-blocks, and the molecular formula is C12H16O7, Recommanded Product: (2R,3R,4R)-2-(Acetoxymethyl)-3,4-dihydro-2H-pyran-3,4-diyl diacetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kim, Ju Won; Baek, Seungkwan; Jung, YeonSoo; Yoon, Wonjae; Ban, Hong Seop; Kwon, Sejin published the artcile< An alternative ADN based monopropellant mixed with tetraglyme>, COA of Formula: C19H34O2, the main research area is ammonium dinitramide water tetraglyme.

In this study, a new monopropellant which consists of ammonium dinitramide (ADN) water solution and tetraethylene glycol di-Me ether (Tetraglyme) fuel is reported. The purpose of research was to improve the specific impulse and to compensate for the preheating temperature and vapor pressure of LMP-103S (63 wt% ADN, 14 wt% water, 18.4 wt% methanol, and 4.6 wt% ammonia). Methanol, ethanol, acetone, and glycerol were also used as the organic fuels to prepare the ADN based monopropellant with and without ammonia solution Further, the characteristic properties and performance of ADN based monopropellants were determined and compared with each other. The thermal properties and explosive power of those monopropellants were performed by using thermogravimetric anal. and differential scanning calorimetry (TGA-DSC) anal. and the blasting cap test, resp. The TGA-DSC anal. revealed that a catalyst active material was an important factor more than the flash point and auto-ignition temperature of fuel for the propellant’s preheating temperature The ADN based monopropellant mixed with tetraglyme exhibited a similar explosive power as with the LMP-103S. Moreover, the theor. vacuum specific impulse of the propellants mixed with tetraglyme was of 1-6% higher than the propellants with other fuels. Overall, ADN water solution blended with tetraglyme may be one of the promising fuel candidates for the satellite application.

Acta Astronautica published new progress about Fuels. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, COA of Formula: C19H34O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ghersetti, S.; Giorgianni, S.; Spunta, G. published the artcile< Far-infrared spectral studies and hydrogen bonding of quinolines>, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is IR quinoline phenol H bond.

The far ir spectra of 14 quinolines with Me, MeO, Br, Cl substituents were analyzed and their absorption frequencies assigned. The intermol. H-bonded complexes obtained by addition of PhOH showed the H bond stretching mode OH…N at 120-30 cm-1 and addnl. bands at 148 cm-1 for the OH…O stretching motion in the methoxyquinoline derivatives A plot of the H bond stretching frequencies of quinolines against those of pyridines showed comparable electronic effects of the ring substituents in the 2 systems and the degree of coupling between the H bond stretching vibration and other low-energy vibrational modes was negligible.

Spectroscopy Letters published new progress about Hydrogen bond. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Recommanded Product: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Rupeng; Cui, Can; Xiao, Rang; Ruinan, L.; Mu, Tiansheng; Huo, Hua; Ma, Yulin; Yin, Geping; Zuo, Pengjian published the artcile< Enabling the conventional TFSI-based electrolytes for high-performance Mg/Li hybrid batteries by Mg electrode interfacial regulation>, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate, the main research area is magnesium lithium electrode interfacial regulation hybrid battery.

The Mg-metal batteries (MMBs) as a forceful competitor for Li-metal batteries (LMBs) have the advantages of high-safety and high-volume energy d. Whereas, the MMBs still confronts two vital issues to be addressed, including the incompatibility of conventional TFSI-based electrolytes with the Mg electrode and the poor reversibility of the cathode. In this work, to satisfyingly settle the incompatibility, an artificial interphase was first pre-constructed by high-temperature displacement reaction of CuCl2 and Mg metal, responsible for the faster charge-transfer rate and the lower Mg plating/stripping overpotential (∼0.2 V) in Mg sym. cells. Regarding the Mg-Mo6S8 full cells, to enhance the reversibility and rate performance, Mg/Li hybrid batteries were designed. Consequently, the Mg-Mo6S8 battery can achieve excellent cycle stability and deliver a desirable capacity. Even as the c.d. increases to 1C, the battery still shows a desirable capacity of 92 mAh g-1 over 500 cycles.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about Current density. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Name: (9Z,12Z)-Methyl octadeca-9,12-dienoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zeng, Kun; Xi, Wenqun; Qiao, Yuanjiao; Huang, Xiaosheng; Liu, Xinhua published the artcile< Paeoniflorin inhibits epithelial mesenchymal transformation and oxidative damage of lens epithelial cells in diabetic cataract via sirtuin 1 upregulation>, Quality Control of 112-63-0, the main research area is human EMT diabetic cataract lens epithelial cells paeoniflorin; EMT; Paeoniflorin; SIRT1; diabetic cataract; lens epithelial cells; oxidative damage.

Paeoniflorin (Pae) has been reported to serve an important role in complications associated with diabetes. To the best of our knowledge, the role of Pae in diabetic cataracts has not yet been reported. Human lens epithelial SRA01/04 cells were induced by high glucose (HG) and subsequently treated with Pae. Cell viability was detected using the MTT assay. Moreover, LDH levels were detected. Immunofluorescence (IF) and Western blotting were used to determine the protein expression levels of N-cadherin and E-cadherin. ELISA was performed to determine oxidative stress-related indicator levels. TUNEL and Western blotting detected the apoptotic rate. The mRNA and protein expression levels of sirtuin 1 (SIRT1) in SRA01/04 cells were measured via reverse transcription-quant. PCR and Western blotting, resp. Subsequently, cell transfection techniques were used to inhibit the expression of SIRT1 in cells. MTT, ELISA, IF, Western blotting and TUNEL assays were used to investigate the mechanisms of epithelial-mesenchymal transition (EMT) and oxidative damage with Pae in the diabetic cataract. Pae significantly increased cell viability and possibly inhibit the EMT and oxidative damage of SRA01/04 cells induced by HG. Pae was demonstrated to upregulate SIRT1 expression levels. The results therefore suggested that the downregulation of SIRT1 reversed the protective effect of Pae on EMT and oxidative damage in SRA01/04 cells induced by HG. In conclusion, Pae may inhibit EMT of lens epithelial cells and reduce oxidative damage in diabetic cataracts via the upregulation of SIRT1.

Bioengineered published new progress about Apoptosis. 112-63-0 belongs to class esters-buliding-blocks, and the molecular formula is C19H34O2, Quality Control of 112-63-0.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics