Tag: M.W=200-250

Polyesters are important plastics, with monomers linked by ester moieties. Phosphoesters form the backbone of DNA molecules. 870-50-8, formula is C10H18N2O4, Name is Di-tert-butyl diazene-1,2-dicarboxylate.Nitrate esters, such as nitroglycerin, are known for their explosive properties. Computed Properties of 870-50-8.

Song, Xue;Zhang, Jie;Wu, Yu-Xing;Ouyang, Qin;Du, Wei;Chen, Ying-Chun research published 《 Asymmetric Formal Nucleophilic o-Cresolylation with Morita-Baylis-Hillman Carbonates of 2-Cyclohexenones via Palladium Catalysis》, the research content is summarized as follows. Here Authors report an asym. formal nucleophilic o-cresolylation reaction with the Morita-Baylis-Hillman (MBH) carbonates from 2-cyclohexanones and diverse aldehydes under palladium catalysis, by in situ generation of electron-neutral and HOMO-raised η2-Pd(0)-dienone complexes via an oxidative insertion/π-σ-isomerization/β-H elimination activation sequence. The subsequent umpolung vinylogous addition to a variety of imines is realized upon Pd(0)-mediated π-Lewis base catalysis, finally furnishing o-cresolylated products followed by another cascade of a π-σ-isomerization/β-H elimination/aromatization process. Moderate to excellent diastereo- and enantioselectivity are achieved for substantial substrate assemblies by employing a newly designed bulky chiral phosphonamidite ligand, and the resultant multifunctional products can be facilely elaborated to access diverse enantioenriched architectures. In addition, the catalytic reaction pathway is finely illuminated by control experiments

870-50-8, Di-tert-butyl azodicarboxylate, also known as Di-tert-butyl azodicarboxylate, is a useful research compound. Its molecular formula is C₁₀H₁₈N₂O₄ and its molecular weight is 230.26 g/mol. The purity is usually 95%.
Di-tert-butyl azodicarboxylate is a reagent used in the electrophilic amination of β-keto esters catalyzed by an axially chiral guanidine. Building block in an enantioselective synthesis of 3,6-dihyropyridazines employing organocatalysts such a L-proline or (S)-2-pyrrolidinyl tetrazole. Utilized in the asymmetric Friedel-Crafts amination via a chiral organocatalyst.
Di-tert-butyl azodicarboxylate is a reagent used in the preparation of acyl hydrazinedicarboxylates via photoorganocatalytic hydroacylation of dialkyl azodicarboxylates with aldehydes in presence of phenylglyoxylic acid as photocatalyst., Computed Properties of 870-50-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Polyesters are important plastics, with monomers linked by ester moieties. Phosphoesters form the backbone of DNA molecules. 87-13-8, formula is C10H16O5, Name is Diethyl 2-(ethoxymethylene)malonate.Nitrate esters, such as nitroglycerin, are known for their explosive properties. Safety of Diethyl 2-(ethoxymethylene)malonate.

Sosa-Gil, Concepcion;Babiano, Reyes;Cintas, Pedro;Light, Mark E.;Palacios, Juan C. research published 《 On the anomeric preference of the isothiocyanato group》, the research content is summarized as follows. This work is aimed at providing a systematic and comprehensive anal. of the anomeric effect exerted by the isothiocyanato group taking the xylopyranose ring as a scaffold because enhanced effects have been detected in that ring-bearing halogen and pseudohalogen substituents. To this end, both α- and β-anomers of tri-O-acetoxypyranosyl-D-xylose have been prepared and thoroughly characterized. The axial preference of the isothiocyanato group reflects a dominant anomeric effect, whose origin could be determined through DFT calculations with identification of the stereoelectronic interactions as revealed by Natural Bond Orbital (NBO) anal. In this way, this study expands the repertoire of groups biasing the conformation and reactivity of monosaccharides and related heterocycles.

Safety of Diethyl 2-(ethoxymethylene)malonate, Diethyl ethoxymethylenemalonate is a useful research compound. Its molecular formula is C10H16O5 and its molecular weight is 216.23 g/mol. The purity is usually 95%.

Diethyl ethoxymethylidenemalonate is a matrix effect reagent used in analytical chemistry. It is often used as a substrate for the cycloaddition process, which produces malondialdehyde and hydrochloric acid. The UV-absorption of the malondialdehyde can be measured to determine the concentration of the sample. Diethyl ethoxymethylidenemalonate is also used as a dna template in binding constants, where it binds with amines to form complexes that are then analyzed by light emission. It has been shown to have an inhibitory effect on gyrase and trifluoroacetic acid, both enzymes involved in DNA replication., 87-13-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Polyesters are important plastics, with monomers linked by ester moieties. Phosphoesters form the backbone of DNA molecules. 87-13-8, formula is C10H16O5, Name is Diethyl 2-(ethoxymethylene)malonate.Nitrate esters, such as nitroglycerin, are known for their explosive properties. SDS of cas: 87-13-8.

Stolpovskaya, N. V.;Kruzhilin, A. A.;Zorina, A. V.;Shikhaliev, Kh. S.;Ledeneva, I. V.;Kosheleva, E. A.;Vandyshev, D. Yu. research published 《 Synthesis of Substituted Aminopyrimidines as Novel Promising Tyrosine Kinase Inhibitors》, the research content is summarized as follows. A procedure was proposed for the synthesis of a series of substituted N-(1,3-thiazol-2-yl)-pyrimidin-2-amines and N-(pyrimidin-2-yl)thioureas by reactions of di-Et 2-(ethoxymethylidene)malonate and Et 2-(ethyoxymethylidene)-3-oxobutanoate with 1,3-thiazol-2-ylguanidines and amidinothiourea, resp. Preliminary screening revealed high inhibitory activity of Et 2-(carbamothioylamino)-4-methylpyrimidine-5-carboxylate and Et 2-(carbamothioylamino)-6-oxo-1,6-dihydropyrimidine-5-carbox-ylate toward several protein kinases.

87-13-8, Diethyl ethoxymethylenemalonate is a useful research compound. Its molecular formula is C10H16O5 and its molecular weight is 216.23 g/mol. The purity is usually 95%.

Diethyl ethoxymethylidenemalonate is a matrix effect reagent used in analytical chemistry. It is often used as a substrate for the cycloaddition process, which produces malondialdehyde and hydrochloric acid. The UV-absorption of the malondialdehyde can be measured to determine the concentration of the sample. Diethyl ethoxymethylidenemalonate is also used as a dna template in binding constants, where it binds with amines to form complexes that are then analyzed by light emission. It has been shown to have an inhibitory effect on gyrase and trifluoroacetic acid, both enzymes involved in DNA replication., SDS of cas: 87-13-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. 87-13-8, formula is C10H16O5, Name is Diethyl 2-(ethoxymethylene)malonate. They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Safety of Diethyl 2-(ethoxymethylene)malonate.

Su, Tong;Zhu, Jiongchang;Sun, Rongqin;Zhang, Huihui;Huang, Qiuhua;Zhang, Xiaodong;Du, Runlei;Qiu, Liqin;Cao, Rihui research published 《 Design, synthesis and biological evaluation of new quinoline derivatives as potential antitumor agents》, the research content is summarized as follows. A series of new quinoline derivatives I [R = 3-F, 3-Br, 3,4-di-Cl, etc.; R¹ = Cl, EtO, OCH₂Ph, etc.] was designed, synthesized and evaluated for their antiproliferative activity. The results demonstrated that compounds I [R = 3-F, 3-MeO, 3-NO₂; R¹ = O(CH₂)₇CH₃, OCH₂Ph, O(CH₂)₃Ph, 4-FC₆H₄CH₂O] exhibited potent antiproliferative activity with IC₅₀ value of lower than 10 μM against seven human tumor cell lines and compound I [R = 3-MeO; R¹ = O(CH₂)₃Ph] was found to be the most potent antiproliferative agent against HCT-116, RKO, A2780 and Hela cell lines with an IC₅₀ value of 2.56, 3.67, 3.46 and 2.71 μM, resp. The antitumor efficacy of the representative compound I [R = 3-MeO; R¹ = O(CH₂)₃Ph] in mice was also evaluated, and the results showed that compound I [R = 3-MeO; R¹ = O(CH₂)₃Ph] effectively inhibited tumor growth and decreased tumor weight in animal models. Further investigation on mechanism of action indicated that compound I [R = 3-MeO; R¹ = O(CH₂)₃Ph] could inhibit colorectal cancer growth through ATG5-depenent autophagy pathway.

87-13-8, Diethyl ethoxymethylenemalonate is a useful research compound. Its molecular formula is C10H16O5 and its molecular weight is 216.23 g/mol. The purity is usually 95%.

Diethyl ethoxymethylidenemalonate is a matrix effect reagent used in analytical chemistry. It is often used as a substrate for the cycloaddition process, which produces malondialdehyde and hydrochloric acid. The UV-absorption of the malondialdehyde can be measured to determine the concentration of the sample. Diethyl ethoxymethylidenemalonate is also used as a dna template in binding constants, where it binds with amines to form complexes that are then analyzed by light emission. It has been shown to have an inhibitory effect on gyrase and trifluoroacetic acid, both enzymes involved in DNA replication., Safety of Diethyl 2-(ethoxymethylene)malonate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Glycerides are fatty acid esters of glycerol; they are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. 87-13-8, formula is C10H16O5, Name is Diethyl 2-(ethoxymethylene)malonate. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Reference of 87-13-8.

Ribeiro, Tania Braganca;Costa, Celia Maria;Bonifacio- Lopes, Teresa;Silva, Sara;Veiga, Mariana;Monforte, Ana Rita;Nunes, Joao;Vicente, Antonio A.;Pintado, Manuela research published 《 Prebiotic effects of olive pomace powders in the gut: In vitro evaluation of the inhibition of adhesion of pathogens, prebiotic and antioxidant effects》, the research content is summarized as follows. Olive pomace is a biowaste rich in polyphenols and insoluble dietary fiber with high potential to develop new value chains towards a sustainable and circular bioeconomy. Regarding gut health, olive pomace phenolics and insoluble dietary fiber (after possible fermentation) could act as antioxidants, antimicrobial and prebiotic agents. These potential beneficial effects on the gut were analyzed for two powders from olive pomace: liquid-enriched powder (LOPP) – mostly source of phenolics – and pulp-enriched powder (POPP) – main source of insoluble dietary fiber. LOPP and POPP were subjected to an in vitro simulated gastrointestinal digestion followed by in vitro faecal fermentation The undigested fraction retained in the colon was analyzed regarding its potential antioxidant, antimicrobial and prebiotic effects. LOPP and POPP did not impact the gut microbiota diversity neg., showing a similar ratio of Firmicutes/Bacteroidetes compared to a pos. control (FOS). LOPP exhibit a pos. (similar to FOS) effect on the Prevotella spp./Bacteroides spp. ratio. Both powders promoted more the production of short-chain fatty acids (mainly acetate > butyrate > propionate) than FOS and showed also significant total phenolic content and oxygen radical absorbance capacity during faecal fermentation until 48 h. Besides that, these powders showed mucin-adhesion inhibition ability against pathogens, principally POPP against Bacillus cereus (22.03 ± 2.45%) and Listeria monocytogenes (20.01 ± 1.93%). This study demonstrates that olive pomace powders have prebiotic effects on microbiota, including the stimulation of short-chain fatty acids production, potential antioxidant and antimicrobial activity which could improve the human gut health.

Reference of 87-13-8, Diethyl ethoxymethylenemalonate is a useful research compound. Its molecular formula is C10H16O5 and its molecular weight is 216.23 g/mol. The purity is usually 95%.

Diethyl ethoxymethylidenemalonate is a matrix effect reagent used in analytical chemistry. It is often used as a substrate for the cycloaddition process, which produces malondialdehyde and hydrochloric acid. The UV-absorption of the malondialdehyde can be measured to determine the concentration of the sample. Diethyl ethoxymethylidenemalonate is also used as a dna template in binding constants, where it binds with amines to form complexes that are then analyzed by light emission. It has been shown to have an inhibitory effect on gyrase and trifluoroacetic acid, both enzymes involved in DNA replication., 87-13-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. 870-50-8, formula is C10H18N2O4, Name is Di-tert-butyl diazene-1,2-dicarboxylate. They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Safety of Di-tert-butyl diazene-1,2-dicarboxylate.

Rostoll-Berenguer, Jaume;Capella-Argente, Murta;Blay, Gonzalo;Pedro, Jose R.;Vila, Carlos research published 《 Visible-light-accelerated amination of quinoxalin-2-ones and benzo[1,4]oxazin-2-ones with dialkyl azodicarboxylates under metal and photocatalyst-free conditions》, the research content is summarized as follows. A direct sp³ C-H amination of cyclic amines (dihydroquinoxalinones and dihydrobenzoxazinones) with dialkyl azo dicarboxylates accelerated by visible-light irradiation under metal and photocatalyst-free conditions is described. This protocol features very mild reaction conditions for the synthesis of aminal quinoxaline and benzoxazine derivatives I (X = NH, N(Me), O; R¹ = allyl, Bn, CH₂COOMe, etc.; R² = COOEt, COOⁱPr, Boc, etc.) with good to high yields (up to 99%). These aminal derivatives respresent versatile building blocks for the divergent synthesis of quinoxalin-2-one derivatives

870-50-8, Di-tert-butyl azodicarboxylate, also known as Di-tert-butyl azodicarboxylate, is a useful research compound. Its molecular formula is C₁₀H₁₈N₂O₄ and its molecular weight is 230.26 g/mol. The purity is usually 95%.
Di-tert-butyl azodicarboxylate is a reagent used in the electrophilic amination of β-keto esters catalyzed by an axially chiral guanidine. Building block in an enantioselective synthesis of 3,6-dihyropyridazines employing organocatalysts such a L-proline or (S)-2-pyrrolidinyl tetrazole. Utilized in the asymmetric Friedel-Crafts amination via a chiral organocatalyst.
Di-tert-butyl azodicarboxylate is a reagent used in the preparation of acyl hydrazinedicarboxylates via photoorganocatalytic hydroacylation of dialkyl azodicarboxylates with aldehydes in presence of phenylglyoxylic acid as photocatalyst., Safety of Di-tert-butyl diazene-1,2-dicarboxylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Glycerides are fatty acid esters of glycerol; they are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. 870-50-8, formula is C10H18N2O4, Name is Di-tert-butyl diazene-1,2-dicarboxylate. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Reference of 870-50-8.

Roy, Sourav;Chatterjee, Indranil research published 《 Visible-Light-Mediated (sp³)Cα-H Functionalization of Ethers Enabled by Electron Donor-Acceptor Complex》, the research content is summarized as follows. A synthetically beneficial visible-light-mediated protocol has been disclosed to achieve C-H amination of readily available feedstocks cyclic and acyclic ethers. A rarely identified N-bromosuccinamide-tetrahydrofuran electron donor-acceptor complex served as an initiator to functionalize both α-diazoketones and dialkyl azodicarboxylates. This developed methodol. gives an alternative and milder way to construct the C-N bond and can be explored for the formation of C-C bond to perform arylation and allylation reactions.

Reference of 870-50-8, Di-tert-butyl azodicarboxylate, also known as Di-tert-butyl azodicarboxylate, is a useful research compound. Its molecular formula is C₁₀H₁₈N₂O₄ and its molecular weight is 230.26 g/mol. The purity is usually 95%.
Di-tert-butyl azodicarboxylate is a reagent used in the electrophilic amination of β-keto esters catalyzed by an axially chiral guanidine. Building block in an enantioselective synthesis of 3,6-dihyropyridazines employing organocatalysts such a L-proline or (S)-2-pyrrolidinyl tetrazole. Utilized in the asymmetric Friedel-Crafts amination via a chiral organocatalyst.
Di-tert-butyl azodicarboxylate is a reagent used in the preparation of acyl hydrazinedicarboxylates via photoorganocatalytic hydroacylation of dialkyl azodicarboxylates with aldehydes in presence of phenylglyoxylic acid as photocatalyst., 870-50-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Glycerides are fatty acid esters of glycerol; they are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. 870-50-8, formula is C10H18N2O4, Name is Di-tert-butyl diazene-1,2-dicarboxylate. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Reference of 870-50-8.

Ruan, Sai;Zhong, Xia;Chen, Quangang;Feng, Xiaoming;Liu, Xiaohua research published 《 An asymmetric hydrocyanation/Michael reaction of α-diazoacetates via Cu(I)/chiral guanidine catalysis》, the research content is summarized as follows. An asym. one-pot hydrocyanation/Michael reaction of α-aryl diazoacetates ArC(N₂)C(O)₂R¹ (Ar = Ph, 4-fluorophenyl, naphthalen-2-yl, etc.; R¹ = Me, Et, i-Pr) with trimethylsilyl cyanide, tert-butanol, and maleimides I (R² = Me, benzyl, 2-fluorophenyl, etc.) has been realized. Using a chiral guanidinium salt/CuBr catalyst, a series of cyanide-containing pyrrolidine-2,5-diones II could be obtained in good yields with excellent diastereo- and enantioselectivities.

870-50-8, Di-tert-butyl azodicarboxylate, also known as Di-tert-butyl azodicarboxylate, is a useful research compound. Its molecular formula is C₁₀H₁₈N₂O₄ and its molecular weight is 230.26 g/mol. The purity is usually 95%.
Di-tert-butyl azodicarboxylate is a reagent used in the electrophilic amination of β-keto esters catalyzed by an axially chiral guanidine. Building block in an enantioselective synthesis of 3,6-dihyropyridazines employing organocatalysts such a L-proline or (S)-2-pyrrolidinyl tetrazole. Utilized in the asymmetric Friedel-Crafts amination via a chiral organocatalyst.
Di-tert-butyl azodicarboxylate is a reagent used in the preparation of acyl hydrazinedicarboxylates via photoorganocatalytic hydroacylation of dialkyl azodicarboxylates with aldehydes in presence of phenylglyoxylic acid as photocatalyst., Reference of 870-50-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Polyesters are important plastics, with monomers linked by ester moieties. Phosphoesters form the backbone of DNA molecules. 870-50-8, formula is C10H18N2O4, Name is Di-tert-butyl diazene-1,2-dicarboxylate.Nitrate esters, such as nitroglycerin, are known for their explosive properties. HPLC of Formula: 870-50-8.

Sadamitsu, Yuta;Saito, Kodai;Yamada, Tohru research published 《 Stereoselective amination via vinyl-silver intermediates derived from silver-catalyzed carboxylative cyclization of propargylamine》, the research content is summarized as follows. The stereoselective synthesis of aminovinyloxazolidinones I (R¹ = Ph, 4-(dimethylamino)phenyl, naphthalen-1-yl, thiophen-2-yl, etc.; R² = Pr, (4-methoxyphenyl)methyl, benzyl; R³ = Me, Et; R⁴ = Et, t-Bu) based on the electrophilic amination of a vinyl-silver intermediate, generated by silver-catalyzed carbon dioxide incorporation on propargyl amines R¹CCC(R³)(R³)NHR², was achieved. The geometry of the aminated product I was determined by a single crystal X-ray anal. and NOE measurement and elucidated that the geometry was proved to be opposite to the geometry predicted from the previous silver-catalyzed carbon dioxide fixation on a propargyl amine derivative This unexpected stereoselectivity could be successfully explained by a radical mechanism.

870-50-8, Di-tert-butyl azodicarboxylate, also known as Di-tert-butyl azodicarboxylate, is a useful research compound. Its molecular formula is C₁₀H₁₈N₂O₄ and its molecular weight is 230.26 g/mol. The purity is usually 95%.
Di-tert-butyl azodicarboxylate is a reagent used in the electrophilic amination of β-keto esters catalyzed by an axially chiral guanidine. Building block in an enantioselective synthesis of 3,6-dihyropyridazines employing organocatalysts such a L-proline or (S)-2-pyrrolidinyl tetrazole. Utilized in the asymmetric Friedel-Crafts amination via a chiral organocatalyst.
Di-tert-butyl azodicarboxylate is a reagent used in the preparation of acyl hydrazinedicarboxylates via photoorganocatalytic hydroacylation of dialkyl azodicarboxylates with aldehydes in presence of phenylglyoxylic acid as photocatalyst., HPLC of Formula: 870-50-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ester is a chemical compound derived from an oxoacid (organic or inorganic) in which at least one –OH hydroxyl group is replaced by an –O– alkyl (alkoxy) group, 87-13-8, formula is C10H16O5, Name is Diethyl 2-(ethoxymethylene)malonate. as in the substitution reaction of a carboxylic acid and an alcohol. COA of Formula: C10H16O5.

Santos, Carine;Pimentel, Luiz;Canzian, Henayle;Oliveira, Andressa;Junior, Floriano;Dantas, Rafael;Hoelz, Lucas;Marinho, Debora;Cunha, Anna;Bastos, Monica;Boechat, Nubia research published 《 Hybrids of Imatinib with Quinoline: Synthesis, Antimyeloproliferative Activity Evaluation and Molecular Docking》, the research content is summarized as follows. In this context, heterocyclic systems, such as quinoline, which is present as a pharmacophore in the structure of the TKI inhibitor bosutinib (BST), was widely applied. Thus, this work aimed to obtain new hybrids of imatinib containing quinoline moieties I [R = CN, CO(O)Et; R¹ = H, Cl; R² = H, Me, MeO, CF₃; R³ = H, Cl; X = Y = C, N] and evaluate them against K562 cells. The compounds were synthesized with a high purity degree. Among the produced mols., the inhibitor I [R = R¹ = R²= R³ = H, X = N, Y = C] showed a suitable reduction in cell viability, with a CC₅₀ value of 0.9μM (IMT, CC₅₀ = 0.08μM). Mol. docking results suggest that the interaction between the most active inhibitor I [R = R¹ = R²= R³ = H, X = N, Y = C] and the BCR-ABL1 enzyme occurs at the bosutinib binding site through a competitive inhibition mechanism. Despite being less potent and selective than IMT, I [R = R¹ = R²= R³ = H, X = N, Y = C] is a suitable prototype for use in the search for new drugs against chronic myeloid leukemia (CML), especially in patients with acquired resistance to IMT.

COA of Formula: C10H16O5, Diethyl ethoxymethylenemalonate is a useful research compound. Its molecular formula is C10H16O5 and its molecular weight is 216.23 g/mol. The purity is usually 95%.

Diethyl ethoxymethylidenemalonate is a matrix effect reagent used in analytical chemistry. It is often used as a substrate for the cycloaddition process, which produces malondialdehyde and hydrochloric acid. The UV-absorption of the malondialdehyde can be measured to determine the concentration of the sample. Diethyl ethoxymethylidenemalonate is also used as a dna template in binding constants, where it binds with amines to form complexes that are then analyzed by light emission. It has been shown to have an inhibitory effect on gyrase and trifluoroacetic acid, both enzymes involved in DNA replication., 87-13-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics