Tag: M.W=200-250

Ulrich, Sebastian; Sadeghpour, Amin; Rossi, Rene M.; Bruns, Nico; Boesel, Luciano F. published the artcile< Wide Range of Functionalized Poly(N-alkyl acrylamide)-Based Amphiphilic Polymer Conetworks via Active Ester Precursors>, SDS of cas: 71195-85-2, the main research area is polyalkylacrylamide amphiphilic polymer network ester precursor.

A versatile strategy for the fabrication of functional poly(N-alkyl acrylamide)-based amphiphilic polymer conetworks (APCNs) from hydrophobic precursor networks is presented. Herein, the active ester monomer pentafluorophenyl acrylate (PFPA) acts as a general hydrophobic masking group for N-alkyl acrylamides. Amidation reactions with different amines allow the transformation of one PFPA-based hydrophobic precursor network into a multitude of different APCNs that possess optical transparency and nanophase-separated morphologies. Accordingly, the properties of these ACPNs can be tailored to the desired application by simple variation of the amide functionality. Furthermore, combination of PFPA with another hydrophobically masked monomer allows for the functionalization of the hydrophilic phase of APCNs in precisely defined amounts Controlled integration of pendant groups such as pH-responsive imidazole, fluorescent dyes, and biotin for specific protein binding is achieved, greatly expanding the functionality of the APCNs. Such functionalized APCNs could find application as stimuli-responsive drug delivery membranes, smart hydrogels, biosensors, or as matrixes for biocatalysis.

Macromolecules (Washington, DC, United States) published new progress about Amidation. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, SDS of cas: 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Choi, Jiyeon; Schattling, Philipp; Jochum, Florian D.; Pyun, Jeffrey; Char, Kookheon; Theato, Patrick published the artcile< Functionalization and patterning of reactive polymer brushes based on surface reversible addition and fragmentation chain transfer polymerization>, Reference of 71195-85-2, the main research area is polypentafluorophenyl acrylate polymer brush RAFT polymerization.

We present the synthesis of reactive polymer brushes prepared by surface reversible addition-fragmentation chain transfer polymerization of pentafluorophenyl acrylate. The reactive ester moieties can be used to functionalize the polymer brush film with virtually any functionality by simple post-polymerization modification with amines. Dithiobenzoic acid benzyl-(4-ethyltrimethoxylsilyl) ester was used as the surface chain transfer agent (S-CTA) and the anchoring group onto the silicon substrates. Reactive polymer brushes with adjustable mol. weight, high grafting d., and conformal coverage through the grafting-from approach were obtained. Subsequently, the reactive polymer brushes were converted with amino-spiropyrans resulting in reversible light-responsive polymer brush films. The wetting behavior could be altered by irradiation with UV or visible light. Furthermore, a patterned surface of polymer brushes was obtained using a lithog. technique. UV irradiation of the S-CTA-modified substrates leads to a selective degradation of S-CTA in the exposed areas and gives patterned activated polymer brushes after a subsequent RAFT polymerization step. Conversion of the patterned polymer brushes with 5-((2-aminoethyl)amino)naphthalene-1-sulfonic acid resulted in patterned fluorescent polymer brush films. The utilization of reactive polymer brushes offers an easy approach in the fabrication of highly functional brushes, even for functionalities whose introduction is limited by other strategies. 漏 2012 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem, 2012.

Journal of Polymer Science, Part A: Polymer Chemistry published new progress about Binding energy. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Reference of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kloeckner, Benjamin; Niederer, Kerstin; Fokina, Ana; Frey, Holger; Zentel, Rudolf published the artcile< Conducting Polymer with Orthogonal Catechol and Disulfide Anchor Groups for the Assembly of Inorganic Nanostructures>, Related Products of 71195-85-2, the main research area is conducting orthogonal catechol disulfide anchor assembly inorganic nanostructure; polyoxyalkylene block graft polyvinylcarbazole coating quantum dot cadmium selenide.

To combine several inorganic components with organic material in a controlled special and permanent manner still remains a difficult issue. Two specifically functionalized block copolymers were synthesized sep. and combined in a second step. A heterofunctional poly(ethylene glycol) (PEG) block copolymer bearing a single amino unit, a short PEG spacer, and multiple catechol functionalities was obtained via anionic ring-opening polymerization (AROP). Using the reversible addition-fragmentation chain transfer (RAFT) radical polymerization technique, a semiconducting block copolymer with carbazole side groups was obtained. The second polyacrylate block contained reactive ester groups and was polymerized onto this hole conducting block. By substitution of the reactive esters with the amino functional PEG-catechol block copolymer and cysteamine Me disulfide, a hole conducting polymer material with two orthogonal anchor groups for the coating of CdSe QDs, and also for TiO2, was obtained. TEM images show that upon coating of both materials we were able to obtain QDs homogeneously distributed at the surface of TiO2 nanoparticles. This spatial assembly is a consequence of the special directing features of the copolymer, possessing two orthogonal anchor groups combined in one material.

Macromolecules (Washington, DC, United States) published new progress about Aggregates. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Related Products of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Demonti, Luca; Saffon-Merceron, Nathalie; Mezailles, Nicolas; Nebra, Noel published the artcile< Cross-Coupling through Ag(I)/Ag(III) Redox Manifold>, Application In Synthesis of 2557-13-3, the main research area is silver trifluoromethyl tervalent argentate preparation reductive elimination arylboronate; trifluoromethyl arene preparation coupling arylboronate trifluoromethylargentate reductive elimination; crystal mol optimized electronic structure tervalent trifluoromethyl argentate complex; AgIII chemistry; cross-coupling; fluorine; high-valent species; trifluoromethylation.

Trifluoromethyl argentates(III) undergo reductive elimination with arylboronic acids, yielding trifluoromethylarenes. In ample variety of transformations, the presence of silver as an additive or co-catalyst is believed to be innocuous for the efficiency of the operating metal catalyst. Even though Ag additives are required often as coupling partners, oxidants or halide scavengers, its role as a catalytically competent species is widely neglected in cross-coupling reactions. Most likely, this is due to the erroneously assumed incapacity of Ag to undergo 2e- redox steps. Definite proof is herein provided for the required elementary steps to accomplish the oxidative trifluoromethylation of arenes through AgI/AgIII redox catalysis (i. e. CEL coupling), namely: (i) easy AgI/AgIII 2e- oxidation mediated by air; (ii) bpy/phen ligation to AgIII; (iii) boron-to-AgIII aryl transfer; and (iv) ulterior reductive elimination of benzotrifluorides from an [aryl-AgIII-CF3] fragment. More precisely, an ultimate entry and full characterization of organosilver(III) compounds [K]+[AgIII(CF3)4]- (K-1), [(bpy)AgIII(CF3)3] (2) and [(phen)AgIII(CF3)3] (3), is described. The utility of 3 in cross-coupling has been showcased unambiguously, and a large variety of arylboron compounds was trifluoromethylated via [AgIII(aryl)(CF3)3]- intermediates. This work breaks with old stereotypes and misconceptions regarding the inability of Ag to undergo cross-coupling by itself.

Chemistry – A European Journal published new progress about Boronic acids, esters Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (arylboronates). 2557-13-3 belongs to class esters-buliding-blocks, and the molecular formula is C9H7F3O2, Application In Synthesis of 2557-13-3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Jochum, Florian D.; Theato, Patrick published the artcile< Temperature- and Light-Responsive Polyacrylamides Prepared by a Double Polymer Analogous Reaction of Activated Ester Polymers>, Quality Control of 71195-85-2, the main research area is polyacrylamide temperature light responsive.

Two different series of polyacrylamides containing different amounts of salicylideneaniline moieties have been synthesized via a double polymer analogous reaction of poly(pentafluorophenyl acrylate) (PPFPA). All copolymers were designed to exhibit a lower critical solution temperature (LCST) in aqueous solution, which was dependent on (i) the amount of incorporated chromophoric salicylideneaniline groups and (ii) the isomerization state of the resp. salicylideneaniline group. Higher LCST values were measured for UV-irradiated solutions of the copolymers in comparison to the nonirradiated copolymer solutions A maximum difference in the LCST of up to 13 °C was found for poly(N-cyclopropylacrylamide) copolymer containing 15.0 mol % of salicylideneaniline groups. Within this temperature range, a reversible solubility change of the copolymer could be induced by irradiation with light.

Macromolecules (Washington, DC, United States) published new progress about Fluoropolymers Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Quality Control of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Eberhardt, Marc; Mruk, Ralf; Zentel, Rudolf; Theato, Patrick published the artcile< Synthesis of pentafluorophenyl (meth)acrylate polymers: New precursor polymers for the synthesis of multifunctional materials>, COA of Formula: C9H3F5O2, the main research area is pentafluorophenyl acrylate methacrylate polymerization amine alc reactivity multifunctional polymer.

Pentafluorophenyl acrylate and -methacrylate were polymerized using AIBN as a thermal initiator. The obtained polymers were soluble polymeric active esters that could be used for the preparation of multifunctional polymers. The reactivity of poly(pentafluorophenyl acrylate) and poly(pentafluorophenyl methacrylate) towards primary and secondary amines, as well as alcs. was investigated in a quant. way. Both poly(active esters) reacted satisfactorily with aliphatic primary and secondary amines but only low conversion was found in the case of aromatic amines. Conversions of only 30% were reached when poly(pentafluorophenyl acrylate) was treated with one equivalent of alc. under base catalysis. In time resolved FT-IR studies the rate constants of the polymer analogous reactions were determined

European Polymer Journal published new progress about Fluoropolymers Role: SPN (Synthetic Preparation), PREP (Preparation). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, COA of Formula: C9H3F5O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Yang; Beija, Mariana; Laurent, Sophie; vander Elst, Luce; Muller, Robert N.; Duong, Hien T. T.; Lowe, Andrew B.; Davis, Thomas P.; Boyer, Cyrille published the artcile< Macromolecular Ligands for Gadolinium MRI Contrast Agents>, Application In Synthesis of 71195-85-2, the main research area is fluoropolymer gadolinium MRI contrast agent preparation.

Macromol. ligands for gadolinium contrast agents (CAs) were prepared via a grafting to strategy. Copolymers of oligoethylene glycol Me ether acrylate (OEGA) and an activated ester monomer, pentafluorophenyl acrylate (PFPA), were synthesized and modified with the 1-(5-amino-3-aza-2-oxypentyl)-4,7,10-tris(tert-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane (DO3A-tBu-NH2) chelate for the complexation of Gd3+. The relaxivity properties of the ligated Gd3+ agents were then studied to evaluate the effect of macromol. architecture on their behavior as magnetic resonance imaging (MRI) CAs. Ligands made from linear and hyperbranched macromols. showed a substantially increased relaxivity in comparison to existing com. Gd3+ MRI contrast agents. In contrast, star nanogel polymers exhibited a slightly lower relaxivity per Gd3+ ion (but still substantially higher relaxivity than existing low mol. weight com. CAs). This work shows that macromol. ligands have the potential to serve as components of Gd MRI agents as there are enhanced effects on relaxivity, allowing for lower Gd concentrations to achieve contrast, while potentially imparting control over pharmacokinetics.

Macromolecules (Washington, DC, United States) published new progress about Cytotoxicity. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Application In Synthesis of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Dao, Nam V.; Ercole, Francesca; Li, Yuhuan; Davis, Thomas P.; Kaminskas, Lisa M.; Sloan, Erica K.; Quinn, John F.; Whittaker, Michael R. published the artcile< Nitroxide-functional PEGylated nanostars arrest cellular oxidative stress and exhibit preferential accumulation in co-cultured breast cancer cells>, Reference of 71195-85-2, the main research area is human breast cancer oxidative stress nitroxide; polyethylene glycol nanostar ROS anticancer.

The limited application of traditional antioxidants to reducing elevated levels of reactive oxygen species (ROS) is potentially due to their lack of stability and biocompatibility when tested in a biol. milieu. For instance, the poor biol. antioxidant performance of small mol. nitroxides arises from their limited diffusion across cell membranes and their significant side effects when applied at high doses. Herein, we describe the use of nanostructured carriers to improve the antioxidant activity of a typical nitroxide derivative, (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO). Polymers with star-shaped structures were synthesized and were further conjugated to TEMPO moieties via amide linkages. The TEMPO-loaded stars have small hydrodynamic sizes (<20 nm), and are better tolerated by cells than free TEMPO in a breast cancer-fibroblast co-culture, a system exhibiting elevated ROS levels. At a well-tolerated concentration, the polymer with the highest TEMPO-loading capacity successfully downregulated ROS production in co-cultured cells (a significant decrease of up to 50% vs. basal ROS levels), which was accompanied by a specific reduction in superoxide anion generation in the mitochondria. In contrast, the equivalent concentration of free TEMPO did not achieve the same outcome. Further investigation showed that the TEMPO-conjugated star polymers can be recycled inside the cells, thus providing longer term scavenging activity. Cell association studies demonstrated that the polymers can be taken up by both cell types in the co-culture, and are found to co-locate with the mitochondria. Interestingly the stars exhibited preferential mitochodria targeting in the co-cultured cancer cells compared to accompanying fibroblasts. The data suggest the potential of TEMPO-conjugated star polymers to arrest oxidative stress for various applications in cancer therapy. Journal of Materials Chemistry B: Materials for Biology and Medicine published new progress about Animal tissue coculture. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Reference of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

zur Borg, Lisa; Domanski, Anna L.; Berger, Ruediger; Zentel, Rudolf published the artcile< Photoinduced Charge Separation of Self-Organized Semiconducting Superstructures Composed of a Functional Polymer-TiO2 Hybrid>, Computed Properties of 71195-85-2, the main research area is polyphenylenevinylene acrylic diblock copolymer titanium dioxide gel charge separation.

The incorporation of TiO2 nanoparticles into long (several micrometers) fibers of a gel-forming poly(para-phenylene vinylene) (PPV) derivative is described. For that purpose, a PPV-block-dopamine polymer is synthesized, which is used to coat TiO2 nanoparticles leading to well-dispersed nanoparticles and fluorescence quenching of the polymer. Independently, the homopolymer gels in various organic solvents are observed to form long fibers. By mixing the PPV homopolymer with the TiO2-PPV hybrid, we are able to incorporate the nanoparticles into the fibrous network, as shown in transmission electron microscopy (TEM) images. Photoinduced charge separation is measured by Kelvin probe force microscopy. Upon illuminating the polymer fibers, pos. charges are observed, even at distances of around 300 nm. From these results, charge transport along the polymer fibers is inferred.

Macromolecular Chemistry and Physics published new progress about Gels, thermally reversible. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Computed Properties of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Park, Jaemin; Nam, Jiyun; Seo, Myungeun; Li, Sheng published the artcile< Side-Chain Density Driven Morphology Transition in Brush-Linear Diblock Copolymers>, Electric Literature of 71195-85-2, the main research area is side chain density morphol transition brush linear diblock copolymer.

We report the synthesis and self-assembly of brush-linear diblock copolymers with variable side-chain length and d. Poly(pentafluorophenyl acrylate-g-ethylene glycol)-b-polystyrene ((PPFPA-g-PEG)-b-PS) brush-linear diblock copolymers are prepared by sequential reversible addition-fragmentation chain transfer (RAFT) polymerization of PPFPA and PS, followed by postpolymn. reaction between the precursor PPFPA-b-PS diblock copolymer and amine-functionalized PEG. By controlling the PEG chain length and the degree of substitution, brush-linear diblock copolymers with different side-chain lengths and densities are obtained. The solid-state morphologies of the diblocks are then examined by small-angle X-ray scattering (SAXS). At low PEG side-chain d., the segregation of PEG and PS away from PPFPA leads to the formation of PEG and PS lamellar domains with PPFPA in the interface. At high PEG side-chain d., the segregation is between the PPFPA-g-PEG brush block and the PS linear block, and the domain morphol. is determined by the composition of the brush block. A partial exptl. phase diagram is presented, and it illustrates the importance of both side-chain length and d. on the microdomain morphol. of brush-linear diblock copolymers.

ACS Macro Letters published new progress about Acrylic polymers, fluorine-containing, block, diblock Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Electric Literature of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics