Tag: M.W=200-250

Asadi, H.; Khoee, S.; Deckers, R. published the artcile< Polymer-grafted superparamagnetic iron oxide nanoparticles as a potential stable system for magnetic resonance imaging and doxorubicin delivery>, Name: Perfluorophenyl acrylate, the main research area is superparamagnetic iron oxide nanoparticle doxorubicin MRI polymer grafting.

Currently, there is high interest in developing multifunctional theranostic platforms with both imaging and therapeutic functions. Herein, we report a facile approach to develop polymer-grafted superparamagnetic iron oxide nanoparticles (SPIONs) as a promising system for imaging and drug delivery. A random copolymer composed of pendant-activated ester moieties, i.e., pentafluorophenyl acrylate (PFPA) and polyethylene glycol monomethyl ether methacrylate (PEGMA), were synthesized and grafted on SPION surfaces using the click reaction. The resultant multifunctional SPIONs were characterized using FT-IR, XRD, XPS, TGA and TEM, proving the presence of polymers on their surfaces. The formed polymer-grafted SPIONs are water-dispersible, stable, and biocompatible as confirmed by a cell viability assay. Relaxivity measurements show that they have a [Formula Omitted] relativity ([Formula Omitted]) of 134.40 mM-1 S-1, which is higher than the value obtained from the com. FDA approved MRI contrast agent Ferumoxytol (85 mM-1 S-1). Furthermore, doxorubicin (DOX) was loaded onto the polymeric shell of modified SPIONs and exhibited fast drug release in response to acidic conditions (pH 5.4). These results clearly indicate that the prepared modified SPIONs have great potential to serve as a multifunctional nanosystem for T2-weighted MR imaging and therapy.

RSC Advances published new progress about Cytotoxicity. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Name: Perfluorophenyl acrylate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Shen, Jinghui; Feng, Shiyu; Ling, Yao; Chang, Chia-Chih; Huang, Chongyu; Wu, Xiaosong; Chen, Shuo; Liu, Jie; Wu, Yonggang; Huang, Weiguo published the artcile< Responsive Zwitterionic Polymers with Humidity and Voltage Dual-Switching for Multilevel Date Encryption and Anticounterfeiting>, Synthetic Route of 71195-85-2, the main research area is responsive zwitterionic polymer humidity voltage switching encryption anticounterfeiting.

Data encryption, protection, and anticounterfeiting are crucial in the modern information society. Though a number of technologies were developed, data security is still facing severe challenges. Herein, a fundamental new approach capable of multilevel data encryption, protection, and anticounterfeiting is developed based on the responsive zwitterionic polymers named as poly(pentafluorophenyl acrylate)-co-poly[(3-((3-acrylamidopropyl)dimethylammonio)propane-1-sulfonate)] (pPFPA-co-pADPS). Detailed studies reveal that zwitterionic polymers exhibit drastic elec. property changes to humidity variation. By reliance of this feature, highly secure touchless palm-based biometric authentication is realized; further, field-effect transistors (FETs) using zwitterionic polymers as dielecs. show nonvolatile memory behaviors with good reliability and rewrite-ability. Remarkably, not only appropriate voltages but also specific humidity range are required to safely decrypt the stored message. In addition, the memory gains the ability to destroy the stored data under counterfeiting/hacking condition, thus preventing the data from being stolen by repeated trials. Therefore, a high level of data security is realized. This work provides new insights into zwitterionic copolymer dielec. based OFETs, demonstrates the first example of double-stage data encryption and protection by OFET memory, and opens up new opportunities for data-securing by responsive materials.

Chemistry of Materials published new progress about Coded information. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Synthetic Route of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Molle, Edgar; Frech, Stefan; Grueger, Tilman; Theato, Patrick published the artcile< Electrochemically-initiated polymerization of reactive monomers via 4-fluorobenzenediazonium salts>, Safety of Perfluorophenyl acrylate, the main research area is electrochem polymerization reactive monomer fluorobenzenediazonium salt.

The straightforward electrochem.-initiated radical polymerization of three reactive monomers, i.e. 2,6-difluorophenyl acrylate (DFPA), pentafluorophenyl acrylate (PFPA), and glycidyl methacrylate (GMA), using a simple com. available electrochem. setup for the generation of initiating radical species from 4-fluorobenzenediazonium tetrafluoroborate upon electrochem. cathodic reduction is reported. The use of a fluorine-labeled initiator allowed for the determination of number-average molar masses Mn of fluorine-containing polymers by 19F NMR spectroscopy in addition to size-exclusion chromatog. The obtained polymers were thereafter successfully subjected to post-polymerization modifications in order to emphasize the applicability of this polymerization method in regard to highly reactive monomers.

Polymer Chemistry published new progress about Acrylic polymers, fluorine-containing Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Safety of Perfluorophenyl acrylate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Obata, Makoto; Yamai, Kouta; Takahashi, Masaki; Ueno, Shintaro; Ogura, Hiroya; Egami, Yasuhiro published the artcile< Synthesis of an oxygen-permeable block copolymer with catechol groups and its application in polymer-ceramic pressure-sensitive paint>, Computed Properties of 71195-85-2, the main research area is oxygen permeable fluoropolymer block catechol ceramic pressure sensitive paint; trifluoroethylisobutyl methacrylate acryloyldopamine block copolymer coating thermal.

An oxygen-permeable block poly(2,2,2-trifluoroethyl-co-iso-Bu methacrylate)-b-poly (N-acryloyldopamine) (FEM-b-PDOPA), in which the PDOPA segment acts as an adhesive section to attach TiO2 nanoparticles, was successfully synthesized via RAFT polymerization followed by a post-polymerization modification with dopamine. Conjugates of FEM-b-PDOPA with TiO2 nanoparticles were prepared by mixing them in chloroform and methanol. IR and solid-state CP-MAS 13C NMR spectroscopies clearly indicated the presence of FEM on the TiO2 nanoparticles. Thermogravimetric anal. of the resulting nanoparticles indicated that FEM-b-PDOPA, rather than FEM alone, was tightly bound to the TiO2 nanoparticles, and that the weight fraction was 2.5 wt%. Polymer-ceramic pressure-sensitive paint was prepared by mixing a luminescent dye, FEM, and TiO2 treated with either FEM-b-PDOPA or native TiO2. In comparison with the coating prepared using native TiO2, the pretreatment of TiO2 with FEM-b-PDOPA effectively reduced the photodegradation of the luminescent dye without deterioration in pressure and temperature sensitivity or dynamic response performance.

Polymer published new progress about Coating materials. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Computed Properties of 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Son, Hyunjoo; Jang, Yeongseon; Koo, Jaseung; Lee, Jeong-Soo; Theato, Patrick; Char, Kookheon published the artcile< Penetration and exchange kinetics of primary alkyl amines applied to reactive poly(pentafluorophenyl acrylate) thin films>, SDS of cas: 71195-85-2, the main research area is alkyl amine polypentafluorophenyl acrylate exchange kinetics.

We investigated the mechanism of primary amine-induced post-polymerization modification of active ester polymer thin films composed of pentafluorophenyl acrylate (PFPA) polymers. The most important phys. parameters in the post-polymerization modification are the mol. weight of the PFPA polymers and the aliphatic chain length of the primary amines. The effects of these two parameters on the penetration depth, as well as the exchange kinetics were systematically studied by neutron reflectivity and quartz crystal microbalance with dissipation, accompanied by the measurement of surface morphol. changes by an at.-force microscopy and optical microscopy. The spin-cast PFPA polymer thin films showed distinctive differences in the exchange kinetics, as well as the penetration depth of amines as a function of the PFPA polymer mol. weight The aliphatic chain length of primary alkyl amines markedly influenced the penetration kinetics into low-mol. weight poly(PFPA) films, whereas there was no significant penetration effect on the high-mol. weight films. The high-mol. weight of the poly(PFPA) films led to the deceleration of the dissolution of amine-functionalized polymer chains in a good solvent. The results of this study may provide a good phys. background for developing reactive poly(PFPA) thin film platforms based on simple and quant. post-modification with amine-containing mols.

Polymer Journal (Tokyo, Japan) published new progress about Diffusion. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, SDS of cas: 71195-85-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bachler, Patricia R.; Forry, Kaitlyn E.; Sparks, Chelsea A.; Schulz, Michael D.; Wagener, Kenneth B.; Sumerlin, Brent S. published the artcile< Modular segmented hyperbranched copolymers>, Formula: C9H3F5O2, the main research area is RAFT polymerization hyperbranched copolymer.

Modular segmented hyperbranched polymers, amenable to facile post-polymerization functionalization, were created via two distinct approaches. Self-condensing vinyl polymerization via reversible addition-fragmentation chain transfer (RAFT) polymerization and RAFT polymerization with a divinyl comonomer were employed to create well-defined highly branched materials containing activated esters amenable to highly efficient functionalization in a modular manner.

Polymer Chemistry published new progress about Branched polymers, hyperbranched dendritic polymers Role: PRP (Properties), SPN (Synthetic Preparation), PREP (Preparation). 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Formula: C9H3F5O2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Lin, Shaojian; Huang, Xia; Guo, Ronghui; Chen, Sheng; Lan, Jianwu; Theato, Patrick published the artcile< UV-triggered CO2-responsive behavior of nanofibers and their controlled drug release properties>, Safety of Perfluorophenyl acrylate, the main research area is acrylic fluoropolymer radical polymerization post polymerization nanofiber electrospinning photocrosslinking; nanofiber controlled release drug delivery system wound dressing.

A novel nanofibrous mat featuring an UV-induced CO2-responsive behavior was fabricated via electrospinning and used as a controlled drug release system. First, a random copolymer for electrospinning, poly(N,N-diethylaminoethyl acrylamide-co-N-benzylacrylamide-co-N,N-dimethyl-N-(2-nitrobenzyl)-ethaneamine acrylamide-co-4-acryloyloxy benzophenone) [P(DEEA-co-BA-co-DMNOBA-co-ABP)], was prepared based on pentafluorophenyl esters via an “”active ester-amine”” chem. reaction. Subsequently, doxorubicin hydrochloride (DOX)-loaded P(DEEA-co-BA-co-DMNOBA-co-ABP) nanofibers were fabricated, yielding a new drug-loaded nanofibrous mat as a potential wound dressing. These DOX-loaded nanofibers can respond to UV irradiation and CO2 stimulation. Interestingly, without UV irradiation, the fabricated nanofibers cannot exhibit any responsiveness. Therefore, the majority of the DOX was steadily stored in the nanofibers, even in the presence of CO2. However, upon UV irradiation, the CO2-responsive behavior of the nanofibers was activated and the prepared nanofibers swelled slightly, resulting in the release of around 42% DOX from the nanofibers. Upon further purging with CO2, the release amount of DOX from the nanofibers could reach up to approx. 85%, followed by the morphol. transition from a nanofibrous mat to a porous hydrogel film. © 2019 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2019.

Journal of Polymer Science, Part A: Polymer Chemistry published new progress about Controlled-release drug delivery systems. 71195-85-2 belongs to class esters-buliding-blocks, and the molecular formula is C9H3F5O2, Safety of Perfluorophenyl acrylate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ichikawa, Yoshiyasu; Hasegawa, Tomoyuki; Minami, Takahiro; Sato, Hiroshi; Morishita, Yukinori; Ochi, Rika; Masuda, Toshiya published the artcile< Further Development of the Tin-Catalyzed Transcarbamoylation Reaction>, COA of Formula: C11H15NO3, the main research area is carbamate preparation; methyl carbamate alc transcarbamoylation tin catalyst; terpene glycoconjugate preparation; glycosyl donor terpene transcarbamoylation tin catalyst.

Studies carried out to further develop tin-catalyzed transcarbamoylation reactions demonstrated that transcarbamoylation of cinnamyl alc. in the context of allyl cyanate-to-isocyanate rearrangement can be efficiently carried out on a ten-gram scale and that tin-catalyzed transcarbamoylation is a valuable alternative to the method using trichloroacetyl isocyanate. In addition, Me carbamate was found to be an economical carabamoyl donor in tin-catalyzed transcarbamoylation, which showed broad functional group tolerance and allowed a streamlined workup procedure. Finally, a unique synthetic method was developed for the preparation of carbamate-tethered terpene glycoconjugates.

Synthesis published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 34637-22-4 belongs to class esters-buliding-blocks, and the molecular formula is C11H15NO3, COA of Formula: C11H15NO3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Biswas, Sayantan; Ghotekar, Balasaheb K.; Kulkarni, Suvarn S. published the artcile< Total Synthesis of the All-Rare Sugar-Containing Pentasaccharide Repeating Unit of the O-Polysaccharide of Plesiomonas shigelloides Strain 302-73 (Serotype O1)>, HPLC of Formula: 34637-22-4, the main research area is aminosugar bacillosamine fucosamine pneumosamine oligosaccharide preparation stereoselective glycosylation catalyst; oligosaccharide aminoglycoside pentasaccharide repeating unit polysaccharide Plesiomonas shigelloides.

First total synthesis of the conjugation-ready pentasaccharide repeating unit of Plesiomonas shigelloides strain 302-73 (serotype O1) is reported. The complex target pentasaccharide is composed of all-rare amino sugars such as orthogonally functionalized D-bacillosamine, L-fucosamine, and L-pneumosamine linked through four consecutive α-linkages. The poor nucleophilicity of axial 4-OH of L-fucosamine and stereoselective glycosylations are the key challenges in the total synthesis, which was completed via a longest linear sequence of 27 steps in 3% overall yield.

Organic Letters published new progress about Amino sugars Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 34637-22-4 belongs to class esters-buliding-blocks, and the molecular formula is C11H15NO3, HPLC of Formula: 34637-22-4.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Qiao, Zhi; Fu, Wen; Zhang, Yongchao; Chen, Ruijia; Xu, Zhiping; Li, Zhong; Shao, Xusheng published the artcile< Azobenzene-Semicarbazone Enables Optical Control of Insect Sodium Channels and Behavior>, HPLC of Formula: 2557-13-3, the main research area is azobenzene semicarbazone optical photoswitching sodium channel insect behavior; invertebrates; metaflumizone; photopharmacology; photoswitches; sodium channels.

Photopharmacol. uses mol. photoswitches to establish control over the action of bioactive mols. The application of photopharmacol. in the research of invertebrate sodium channels has not been investigated. Here we report several photochromic ligands of metaflumizone. One ligand, termed ABM04 (I), underwent reversible trans-cis isomerization under UV or blue light irradiation cis-ABM04 had excellent larvicidal activity against mosquito larvae with an LC50 value of 4.39 μM and showed insecticidal activity against Mythimna separata with an LC50 value of 7.19 μM. However, trans-ABM04 was not found to have biol. activity. ABM04 (10 μM) can induce depolarization of dorsal unpaired median neurons and enable the real-time photoregulation of mosquito larval behavior. The precise regulation of invertebrate sodium channels is realized for the first time, which provides a new strategy for the basic and accurate research of invertebrate sodium channels.

Journal of Agricultural and Food Chemistry published new progress about Aedes albopictus. 2557-13-3 belongs to class esters-buliding-blocks, and the molecular formula is C9H7F3O2, HPLC of Formula: 2557-13-3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics