Tag: M.W=200-250

Rabizadeh, E. published the artcileDoxorubicin and a butyric acid derivative effectively reduce levels of bcl-2 protein in the cells of chronic lymphocytic leukemia patient, Safety of (Pivaloyloxy)methyl butyrate, the publication is European Journal of Haematology (2001), 66(4), 263-271, database is CAplus and MEDLINE.

B-chronic lymphocytic leukemia (B-CLL) is a disease caused primarily by defects in the apoptosis mechanism. AN-9, a butyric acid (BA) derivative, is a potent differentiating and an anti-cancer drug that induces apoptosis in HL-60 cells. Herein the authors show the effect of AN-9, alone and in combination with doxorubicin, on cell cultures from B-CLL patients. Cells from 17 patients were cultured and tested for viability, apoptosis, bcl-2, and Bax protein expression. Exposure of B-CLL cell cultures to AN-9 was accompanied by apoptosis and a marked viability loss (up to 46%, p=0.0017). AN-9 reduced up to 51% (p=0.0017) the levels of bcl-2 in 57% of the cultures that express bcl-2. The combination of low concentrations of AN-9 and doxorubicin more than additively enhanced apoptosis and reduced bcl-2 levels in B-CLL cultures which were resistant to AN-9. AN-9 enhanced Bax expression up to 58% (p=0.008) in cultures from 53% of the patients but had no effect on Bax levels when combined with doxorubicin. In conclusion, AN-9 alone reduced bcl-2 and enhanced Bax expression in cultures from B-CLL patients, and the reduction of bcl-2 levels in combination with doxorubicin was greater than additive. These results may be beneficial in possible future combination therapy with AN-9 in B-CLL.

European Journal of Haematology published new progress about 122110-53-6. 122110-53-6 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester,Inhibitor, name is (Pivaloyloxy)methyl butyrate, and the molecular formula is C10H18O4, Safety of (Pivaloyloxy)methyl butyrate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Wakamura, Sadao published the artcileSex pheromone of the fall armyworm Spodoptera frugiperda (Lepidoptera: Noctuidae) of a “Far East” population from Okinawa, Japan, Safety of (Z)-Dodec-9-en-1-yl acetate, the publication is Applied Entomology and Zoology (2021), 56(1), 19-25, database is CAplus.

Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae) is native to the Americas and has recently invaded Okinawa, Japan via Africa, South Asia and China. Gas chromatog./mass spectrometry analyses of hexane extracts of 100 abdominal glands of Okinawan females revealed six candidate compounds for sex pheromone, (Z)-9-tetradecenyl acetate (Z9-14:Ac, ca. 6 ng/female), (Z)-11-hexadecenyl acetate, (Z)-11-tetradecenyl acetate, (Z)-7-dodecenyl acetate (Z7-12:Ac), (E)-9-dodecenyl acetate, and (Z)-9-tetradecen-1-ol at the ratio of 100:10:1.3:0.90:0.13:1.8, resp. In Okinawa, only small numbers of males were captured with the original blend of these compounds However, much more males were attracted to a 100:3 blend of Z9-14:Ac and Z7-12:Ac that had been suggested by others to be the most effective blend in a Florida population. In another test in Okinawa, even more males were captured with a 100:1 blend of these compounds than with a 100:3 blend. Significant numbers of males of other moths, Mythimna loreyi (Duponchel) and Chrysodeixis eriosoma (Doubleday), were also attracted to blends of Z9-14:Ac and Z7-12:Ac when the ratio of the latter to the former compound was increased from 100:1 to 100:10. Based on these results we concluded that the most powerful as well as convenient sex pheromone formulation to monitor S. frugiperda populations in Okinawa was a 100:1 blend of Z9-14:Ac and Z7-12:Ac.

Applied Entomology and Zoology published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C15H12O8, Safety of (Z)-Dodec-9-en-1-yl acetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Guerin, P. M. published the artcileSex pheromone of Adoxophyes orana: additional components and variability in ratio of (Z)-9- and (Z)-11-tetradecenyl acetate, Recommanded Product: (Z)-Dodec-9-en-1-yl acetate, the publication is Journal of Chemical Ecology (1986), 12(3), 763-72, database is CAplus and MEDLINE.

Twelve products related to the sex pheromone main components (Z)-9- and (Z)-11-tetradecenyl acetate (Z9-14:Ac and Z11-14:Ac, resp.), were identified in female pheromone gland extracts of the laboratory-reared summerfruit tortrix moth, A. orana. These are the geometric isomers and the alcs. of the main components, (Z)-9-dodecenyl acetate, (Z)-11-hexadecenyl acetate, and saturated acetates of 12-22 carbons. The ratios of Z9-14:Ac to Z11-14:Ac in individuals varied from 3.5:1 to 11:1 with an average of 6.2; their total added up to 462 ng/female with an average of 182 ng for 2- to 7-day-old individuals. No qual. or quant. differences were observed between laboratory and field insects. Z9-14:Ac, Z11-14:Ac and the corresponding alcs. were also found in female effluvia. Addition of either of the 2 alcs. to a blend of the 2 acetates augmented trap catch in the field. The same was true for (Z)-9,(E)-12-tetradecadienyl acetate which was not detected in gland extracts

Journal of Chemical Ecology published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Recommanded Product: (Z)-Dodec-9-en-1-yl acetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Guerin, P. M. published the artcileThe sex pheromone of Adoxophyes orana. Preliminary findings from a reinvestigation, Safety of (Z)-Dodec-9-en-1-yl acetate, the publication is Colloques – Institut National de la Recherche Agronomique (1982), 267-9, database is CAplus.

Mixtures including minor components of the pheromone blend of A. orana were more attractive to males than mixtures containing only the 2 main components, (Z)-9- and (Z)-11-tetradecenylacetates. The minor components principally responsible appeared to be (Z)-9- and (Z)-11-tetradecenyl alcs. and (E)-11-tetradecenylacetate. The 2 main components were effective over a wide range of ratios, and a considerable age-dependent variation was observed in the ratio of these 2 isomers in females.

Colloques – Institut National de la Recherche Agronomique published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Safety of (Z)-Dodec-9-en-1-yl acetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Buser, Hans Rudolf published the artcileDetermination of double bond position in mono-unsaturated acetates by mass spectrometry of dimethyl disulfide adducts, Recommanded Product: (Z)-Dodec-9-en-1-yl acetate, the publication is Analytical Chemistry (1983), 55(6), 818-22, database is CAplus.

Forty-seven model compounds (decenyl to octadecenyl acetates) in nanogram quantities were reacted with Me₂S₂ and the derivatives analyzed by high-resolution gas chromatog. and electron-impact mass spectrometry. The derivatives yield easily recognizable mol. ions. Cleavage between the sulfur-substituted carbons leads to key fragments which allow a determination of the position of the double bond in the original mono-unsaturated acetate. The procedure is applied in the identification of mono-unsaturated acetates in pheromone extracts of two moth species.

Analytical Chemistry published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Recommanded Product: (Z)-Dodec-9-en-1-yl acetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Rauscher, Stefan published the artcileEffects of dodecyl acetate and Z-10-tridecenyl acetate on attraction of Eupoecilia ambiguella males to the main sex pheromone component, Z-9-dodecenyl acetate, Recommanded Product: (Z)-Dodec-9-en-1-yl acetate, the publication is Journal of Chemical Ecology (1984), 10(2), 253-64, database is CAplus and MEDLINE.

Attraction of E. ambiguella males to Z-9-dodecenyl acetate (Z9-12:Ac) [16974-11-1], alone and in combination with dodecyl acetate (12:Ac) [112-66-3] or Z-10-tridecenyl acetate (Z10-13:Ac) [64437-24-7] was tested in both wind-tunnel and field experiments In the laboratory, response to Z9-12:Ac reached a distinct dosage optimum at which attraction was nearly as good as to live females. Addition of 12:Ac, a minor component of female glands and effluvia, had no effect at low doses of Z9-12:Ac and only marginally improved attraction at the optimum. However, inclusion of 12:Ac with an overdose of Z9-12:Ac, fully restored activity. In the field, Z9-12:Ac alone was not very attractive at any dose; catches markedly increased by adding 12:Ac and climbed with increasing dose of each compound ≤10 mg. Optimum ratio of Z9-12:Ac to 12:Ac was 1:1-1:5. Z10-13:Ac, had the same effect as 12:Ac in the laboratory and the field, but was effective at a lower dose. In the field, inclusion of the synergist permits use of high cap loads to attract more males, perhaps from greater distances.

Journal of Chemical Ecology published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Recommanded Product: (Z)-Dodec-9-en-1-yl acetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Azizi, Najmedin published the artcileStraightforward and Highly Efficient Catalyst-Free One-Pot Synthesis of Dithiocarbamates under Solvent-Free Conditions, HPLC of Formula: 3052-61-7, the publication is Organic Letters (2006), 8(23), 5275-5277, database is CAplus and MEDLINE.

A highly efficient and simple synthesis of dithiocarbamates, e.g. I, based on the one-pot reaction of amines, CS₂, and alkyl halides without using a catalyst under solvent-free conditions, is reported. The mild reaction conditions, high yields, and broad scope of the reaction illustrate the good synthetic utility of this method. The reaction is a highly atom-economic process for production of S-alkyl thiocarbamates and successfully can be used in high quantities in the pharmaceutical or agrochem. industries.

Organic Letters published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, HPLC of Formula: 3052-61-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Azizi, Najmedin published the artcileVersatile and large-scale synthesis of functional dithiocarbamates in water, COA of Formula: C12H17NS2, the publication is Synthetic Communications (2011), 41(1), 94-99, database is CAplus.

Structural diversity is possible in direct access to functional dithiocarbamates based on a highly efficient and simple one-pot reaction of CS₂, amines, and alkyl halides in nearly quant. yields in water.

Synthetic Communications published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, COA of Formula: C12H17NS2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ljungberg, H. published the artcilePhysiology and morphology of pheromone-specific sensilla on the antennae of male and female Spodoptera littoralis (Lepidoptera: Noctuidae), COA of Formula: C14H26O2, the publication is Journal of Insect Physiology (1993), 39(3), 253-60, database is CAplus.

The physiol., morphol. and distribution of pheromone receptors on the antennae of both sexes of Spodoptera littoralis Boisd. (Lepidoptera: Noctuidae) were investigated by electroantennogram screening, single sensillum recordings and SEM. The electroantennogram recordings showed maximal responses to (Z,E)-9,11-tetradecadienyl acetate in males and to (Z)-7-dodecenyl acetate in females. In subsequent single sensillum recordings, receptor cells specific for the two known pheromone components, (Z,E)-9,11-tetradecadienyl acetate and (Z,E)-9,12-tetradecadienyl acetate, as well as for the behavioral antagonist (Z)-9-tetradecenol, were found in both sexes. The sensitivity of the pheromone receptors to their resp. stimuli was the same in the sexes, while the number of pheromone-specific sensilla was much lower in the female. In the male, two physiol. distinct sensillum types were differently distributed over the antennal surface. The most numerous type, containing only one receptor neuron specific for (Z,E)-9,11-tetradecadienyl acetate, was evenly distributed over the ventral antennal surface, while a sensillum type containing one neuron responding to (Z,E)-9,12-tetradecadienyl acetate and one neuron specific for (Z)-9-tetradecenol was only found among more laterally situated sensilla. This distribution was not observed in the female.

Journal of Insect Physiology published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, COA of Formula: C14H26O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Lanne, Boel S. published the artcileDetermination of the double bond position in monounsaturated acetates from their mass spectra, Related Products of esters-buliding-blocks, the publication is Analytical Chemistry (1985), 57(8), 1621-5, database is CAplus.

A simple method with widespread applicability in determining double bond positions in C₁₂, C₁₄, and C₁₆ straight-chain monounsaturated acetates is presented. The anal. is made with a capillary gas chromatograph coupled to a low-resolution mass spectrometer which is operated in the electron impact mode. No chem. derivatization of the unknowns is needed. Five pairs of selected mass spectra fragments are chosen to distinguish positional isomers. A new math. model is introduced which permits simultaneous comparisons of all 5 ratios of unknowns and references The method can be used for analyses of very small amounts (≤5 ng) of unknown acetates in insect samples.

Analytical Chemistry published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics