Tag: M.W=200-250

Fernandez-Blazquez, Juan P. published the artcileObservation of Two Glass Transitions in a Thermotropic Liquid-Crystalline Polymer, Category: esters-buliding-blocks, the publication is Macromolecules (2004), 37(24), 9018-9026, database is CAplus.

DSC and real-time variable-temperature synchrotron experiments have been performed on a thermotropic poly(ether-ester), PH31B32, with biphenyl units as mesogens and spacers with Me substituents. It has been found that PH31B32 develops a low-ordered SmCalt mesophase with a rather slow rate of formation in such a way that the isotropic melt of this polymer can be easily quenched into the glassy amorphous state at the usual cooling rates of the calorimeter. Considerably high annealing times at temperatures above T_g are necessary to develop such a mesophase. The extent of transformation and symmetry of the mesophase have been determined by means of calorimetric and X-ray diffraction experiments The DSC results show that the glass-transition temperatures of the amorphous and liquid-crystalline states are clearly different: 95 and 84 °C, resp. Moreover, the results show that the isotropization temperature increases linearly with the annealing temperature (the temperature at which the mesophase has been formed). The synchrotron experiments show that the mesophase layer spacing is slightly lower for the higher annealing temperatures, indicating a slightly more compact structure. Although the WAXS profiles of the two phases (mesophase and amorphous) are rather similar, the mesophase has noticeably smaller most probable intermol. distances and a smaller width of the WAXS broad peak. The temperature coefficients of these intermol. distances are also different for the various phases, and clear discontinuities are observed at the glass transitions. The corresponding values of T_g obtained from these results are 94 and 84 °C for the amorphous and liquid-crystalline phases, resp., in perfect agreement with the DSC results. The correlation lengths estimated from the widths of the mesophase layer peaks are of the order of the extended chain length of the polymer, so that no extensive chain folding seems to be present in the mesophase of PH31B32. This fact will favor the attainment of high degrees of liquid crystallinity. Moreover, the higher correlation lengths deduced for the higher annealing temperatures point to a segregation of defects from the smectic structure in a greater extent, which may explain the corresponding higher isotropization temperatures

Macromolecules published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ammar, Samia published the artcileEssential oils from the halophytic plant Atriplex inflata F. Muell: chemical composition, antioxidant and antimicrobial activities, Category: esters-buliding-blocks, the publication is Journal of Medicinal and Aromatic Plant Sciences (2012), 34(3&4), 132-144, database is CAplus.

The present work was carried out to determine the chem. composition and to evaluate the antioxidant and the antimicrobial proprieties of the essential oil extracted from the different plant parts of Atriplex inflata F. Muell. In addition to essential oil, some organic extracts were also tested. Based on the GC/MS anal., difference in composition between leaves, fruits and roots was noticed. The antioxidant capacity of the volatile fractions and the organic extracts was determined by the inhibition of DPPH and ABTS⁺ radical forms. A pos. activity was observed in volatile fraction of leaves. Antimicrobial activity was evaluated by the determination of the minimal inhibition concentration (MIC) using the ethanolic and the acetonic extracts and the volatile fractions from fruits, leaves and roots. Bacteria and yeasts were found to be more sensitive towards volatile fraction extracted from the A. Inflata leaves.

Journal of Medicinal and Aromatic Plant Sciences published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Witzgall, P. published the artcileSex pheromone of grape berry moth (Lepidoptera: Tortricidae), Recommanded Product: (Z)-Dodec-9-en-1-yl acetate, the publication is Environmental Entomology (2000), 29(3), 433-436, database is CAplus.

Pheromone gland extracts of grape berry moth females, Endopiza viteana Clemens, contain the main pheromone component, Z9-12Ac, at ≈1.2 ng per female, together with both geometric isomers of 11-14Ac, and a number of saturated acetates and alcs. of the chain length 12-16. The analogous alc., Z9-12OH, was found in some gland extracts Trap capture of males was significantly increased by adding 0.5 or 2 μg of Z11-14Ac to 10 μg of the main compound, Z9-12Ac; whereas, adding 0.5 or 2 μg of E11-14Ac had no significant effect. In contrast, the addition of 5% Z9-12OH to the main compound resulted in a strong reduction in trap capture. Traps baited with a blend of Z9-12Ac and its geometric isomer, E9-12Ac, which was not detected in gland extracts, were significantly less attractive than traps baited with blends of Z9-12Ac and Z11-14Ac. Knowledge of pheromone components and antagonists is essential for development of the mating disruption technique. The compounds identified in E. viteana are behaviorally active in the three most important tortricid pests of grape, Vitis vinifera (L.), in Europe. It may thus be possible to use a single blend of synthetic pheromone for control of several species.

Environmental Entomology published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C7H10O4, Recommanded Product: (Z)-Dodec-9-en-1-yl acetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Mali, Sachitanand M. published the artcileSynthesis of α, β-unsaturated γ-amino esters with unprecedented high (E)-stereoselectivity and their conformational analysis in peptides, Recommanded Product: (R)-tert-Butyl (3-methyl-1-oxobutan-2-yl)carbamate, the publication is Organic & Biomolecular Chemistry (2011), 9(19), 6566-6574, database is CAplus and MEDLINE.

Mild, efficient and racemization-free synthesis of N-protected α, β-unsaturated γ-amino esters with unprecedented high E- stereoselectivity is described. This method is found to be compatible with Boc- (Boc = tert-butoxycarbonyl), Fmoc- (Fmoc = 9-fluorenylmethoxycarbonyl) and other side chain protecting groups. The crystal conformations of the vinylogous γ-amino esters in monomers and in homo- and mixed dipeptides are studied. Further, the vinylogous homo-dipeptide showed a β-sheet conformation, while mixed α- and α,β-unsaturated γ-hybrid dipeptide adapted an irregular structure in single crystals.

Organic & Biomolecular Chemistry published new progress about 106391-88-2. 106391-88-2 belongs to esters-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Aldehyde, name is (R)-tert-Butyl (3-methyl-1-oxobutan-2-yl)carbamate, and the molecular formula is C10H19NO3, Recommanded Product: (R)-tert-Butyl (3-methyl-1-oxobutan-2-yl)carbamate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Faya, V. published the artcileS_C^* and S_C̃^_* phases in chiral non-symmetric dimesogens, Application of Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, the publication is Liquid Crystals (1996), 21(4), 485-503, database is CAplus.

The authors synthesized two sep. homologous series of chiral nonsym. dimesogens: these have a two Ph ring moiety bearing a terminal alkoxy chain linked via a methylenic spacer to a chiral three Ph ring mesogen which itself displays antiferroelec. properties. Depending on the parity of the number of carbons constituting the spacer, two kinds of mesomorphic behavior were found. When the spacer is even, various S_C^* phases (S_C^*A,S_C^*FI,S_C^*,S_C^*α) were identified without doubt, whereas when the spacer is odd, a tilted modulated phase (S_C̃^*) was observed and characterized. In each case, the authors study the effect of the length of the alkoxy chain at the end of the shorter moiety. The alternation of the mesomorphic behavior with the spacer parity was interpreted in terms of mol. shape, but the authors have also discussed the influence of some chem. parameters on the stability of the S_C^*A phase.

Liquid Crystals published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, Application of Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Winter-Holt, Jon J. published the artcileDiscovery of a Potent and Selective ATAD2 Bromodomain Inhibitor with Antiproliferative Activity in Breast Cancer Models, Category: esters-buliding-blocks, the publication is Journal of Medicinal Chemistry (2022), 65(4), 3306-3331, database is CAplus and MEDLINE.

ATAD2 is an epigenetic bromodomain-containing target which is overexpressed in many cancers and has been suggested as a potential oncol. target. While several small mol. inhibitors have been described in the literature, their cellular activity has proved to be underwhelming. In this work, we describe the identification of a novel series of ATAD2 inhibitors by high throughput screening, confirmation of the bromodomain region as the site of action, and the optimization campaign undertaken to improve the potency, selectivity, and permeability of the initial hit. The result is compound 5 (AZ13824374)(I), a highly potent and selective ATAD2 inhibitor which shows cellular target engagement and antiproliferative activity in a range of breast cancer models.

Journal of Medicinal Chemistry published new progress about 106391-88-2. 106391-88-2 belongs to esters-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Amide,Aldehyde, name is (R)-tert-Butyl (3-methyl-1-oxobutan-2-yl)carbamate, and the molecular formula is C8H5F3O2S, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Loudet, J. C. published the artcileColloidal Structures from Bulk Demixing in Liquid Crystals, COA of Formula: C15H14O3, the publication is Langmuir (2004), 20(26), 11336-11347, database is CAplus and MEDLINE.

This exptl. paper deals with phase separations of binary mixtures composed of a continuous liquid crystal phase and an isotropic dispersed phase. In contrast to isotropic binary mixtures, the studied mixtures do not lead to a full phase separation but to a self-ordering of colloidal particles, as reported earlier (Loudet, J. C. et al., Nature 2000, 407, 611). The authors present here further aspects of such phase separations which include the kinetics of the phase separation, the origin of the formation of dislocation-like patterns, the influence of surfactants, chiral additives, and temperature on the formed colloidal structures. (i) The dislocations in chain arrays can be seen as kinetically frozen defects, (ii) temperature can be used to control the size of the domains formed upon demixing, (iii) a slight change in surface chem., via the addition of surfactants, profoundly alters the formed colloidal structures, and (iv) chiral additives gave unique helical pearl chains which reflect the symmetry of the liquid crystal phase they are embedded in.

Langmuir published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, COA of Formula: C15H14O3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Bestmann, Hans Juergen published the artcile(Z)-9-Dodecenyl acetate, a component of the sex pheromone of Cnephasia longana Haworth (Lepidoptera: Tortricidae), Computed Properties of 16974-11-1, the publication is Zeitschrift fuer Naturforschung, C: Journal of Biosciences (1985), 40C(9-10), 667-9, database is CAplus.

(Z)-9-Dodecenyl acetate is a component of the sex pheromone of female C. longana moths as determined by gas chromatog (GC)-, GC-mass spectrometry anal. of gland extracts, and GC anal. with electroantennogram detection. (E)-9-Dodecenyl acetate acted as a pheromone inhibitor, as shown by field trials.

Zeitschrift fuer Naturforschung, C: Journal of Biosciences published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Computed Properties of 16974-11-1.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Vekey, Karoly published the artcileIdentification of Z and E isomers by chemical ionization, Safety of (Z)-Dodec-9-en-1-yl acetate, the publication is Biomedical & Environmental Mass Spectrometry (1988), 16(1-12), 267-8, database is CAplus.

A method is described for differentiation between the Z and E isomers of long-chain monounsaturated acetates without the need for chem. derivatization and special instrumentation. Chem.-ionization spectra were recorded on a VG MM-12 single-focusing mass spectrometer using a combined electron-impact/chem.-ionization source. Samples were introduced via a gas chromatograph using a glass column packed with SE-30 stationary phase. The model compounds were (Z)-Me(CH₂)_nCH:CH(CH₂)_mOAc (n = 1 or 3, m = 4, 8, or 10) and its E isomer.

Biomedical & Environmental Mass Spectrometry published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C9H12O, Safety of (Z)-Dodec-9-en-1-yl acetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Hua, Daoben published the artcileDithiocarbamate mediated controlled/living free radical polymerization of methyl acrylate under ⁶⁰Co γ-ray irradiation: Conjugation effect of N-group, Synthetic Route of 3052-61-7, the publication is Journal of Polymer Science, Part A: Polymer Chemistry (2004), 42(22), 5670-5677, database is CAplus.

The free radical polymerizations of Me acrylate have been studied under γ-ray irradiation in the presence of the dithiocarbamates with different N-groups. The results indicate that the conjugation structure of the N-group of dithiocarbamate plays an important role in living free radical polymerization The polymerizations reveal good living characteristics in the presence of dithiocarbamates (benzyl 1H-imidazole-1-carbodithioate, benzyl 1H-pyrrole-1-carbodithioate, benzyl 1H-indole-1-carbodithioate, and benzyl 9H-carbazole-9-carbodithioate) with N-aryl group. In contrast, the polymerization with benzyl N,N-diethyldithiocarbamate cannot be controlled, and the obtained polymer has a broad mol. weight distribution or even crosslink occurs. Moreover, polymerization rate is influenced by the conjugation structure of the N-group of dithiocarbamate, and the aromatic polycyclic structure of the N-group leads to slow polymerization

Journal of Polymer Science, Part A: Polymer Chemistry published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, Synthetic Route of 3052-61-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics