Tag: M.W=200-250

Cheng, Zihui published the artcileInfluence of linkage and terminal group on the liquid crystalline and helical twisting behaviors of cholesteryl esters, Formula: C15H14O3, the publication is Liquid Crystals (2011), 38(7), 803-812, database is CAplus.

Three series of cholesteryl esters with different linkages and terminal groups were synthesized and characterized. All esters except cholesteryl 6-bromohexanoate can exhibit thermotropic liquid crystalline phases in certain temperature regions. The insertion of a 4-phenoxy and a 4-biphenylyloxy group in the ester can increase the mol. length, broaden the whole mesophase width and heighten the clearing temperature The increasing mol. length can enforce the layered arrangement in series A and B (resulting in a monolayer smectic A phase), while destroying the layer stacking in series C (resulting in a suppressed or absent intertwined smectic A phase). Meanwhile, the mol. structure played an important role in the molar helical twisting power and its temperature dependence. The target compounds thus formed included cholesterol esters, (3β)-cholest-5-en-3-ol 3-[6-(2-naphthalenyloxy)hexanoate] and (3β)-cholest-5-en-3-ol 3-[6-[(4′-cyano[1,1′-biphenyl]-4-yl)oxy]hexanoate] and corresponding benzoate and biphenylcarboxylate derivatives

Liquid Crystals published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, Formula: C15H14O3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Li, Hong published the artcileHemin loaded Zn-N-C single-atom nanozymes for assay of propyl gallate and formaldehyde in food samples, SDS of cas: 121-79-9, the publication is Food Chemistry (2022), 132985, database is CAplus and MEDLINE.

Single-atom nanozymes (SAzymes) show distinct advantages in catalytic activity and selectivity owing to their stability and special characteristic of maximum at. utilization. Inspired by the structure of natural horseradish peroxidase (HRP), we developed a simple method for specific determination of both Pr gallate (PG) and formaldehyde (HCHO) by utilizing the intrinsic peroxidase mimics activity of hemin (hem) loaded Zn-nitrogen-carbon single-atom nanozymes (Zn-N-C@hem SAzymes). Zn-N-C@hem was prepared via a salt-template strategy and self-assembly, where hemin exhibits enhancing peroxidase-like activity can catalyze oxidation of colorless PG to yellow product. Upon introduction of HCHO into Zn-N-C@hem/PG system, complete suppression of PG oxidation was showed, resulting in distinguished decrease in absorbance. The colorimetric sensors of PG and HCHO based on Zn-N-C@hem/PG were developed at their resp. linear range of concentration 1.25-200 mg/kg and 5-250 mg/kg. The practicability of the rapid anal. of PG and HCHO in food samples has been verified with reliable results.

Food Chemistry published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C10H12O5, SDS of cas: 121-79-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Yang, Dezhi published the artcileA multifunctional nanozyme-based enhanced system for tert-butyl hydroquinone assay by surface-enhanced Raman scattering, Safety of Propyl 3,4,5-trihydroxybenzoate, the publication is Microchimica Acta (2022), 189(1), 29, database is CAplus and MEDLINE.

An Au-based nanozyme composite (AuNPs/Cu,I) was constructed by using Cu,I-doped carbon dots (Cu,I-CDs) as the reducing agent as well as the nanozyme. Notably, AuNPs/Cu,I nanozyme not only possessed the intrinsic activity of mimicking enzymes of superoxide dismutase, peroxidase, and catalase at different conditions but was also employed as surface-enhanced Raman spectroscopy (SERS) enhancer. The combination of Cu,I-CDs and AuNPs promoted the electron transferability, leading to increased peroxidase-like activity and superoxide-like activity. Compared to the individual Cu,I-CDs and AuNPs nanozyme, the AuNPs/Cu,I composite demonstrated promising peroxidase-like activity by transferring electrons instead of generating OH. Interestingly, the multienzyme-like activity of AuNPs/Cu,I nanozyme could be finely tuned by changing the composition of Cu0/Cu+ and Au. The tert-Bu hydroquinone (TBHQ) as the substrate could be catalyzed with AuNPs/Cu,I nanozyme to produce red substances, resulting in a significant Raman enhancement effect at the same time, showing good linear range from 0.11 to 10 mg L^-1. Overall, the current investigation provides a flexible and controllable way to design multifunctional nanozymes along with the Raman enhancement strategy based on the catalysis of nanozyme.

Microchimica Acta published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C6H13I, Safety of Propyl 3,4,5-trihydroxybenzoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Lan, Ya-Qian published the artcileTailor-Made Metal-Organic Frameworks from Functionalized Molecular Building Blocks and Length-Adjustable Organic Linkers by Stepwise Synthesis, HPLC of Formula: 50670-76-3, the publication is Chemistry – A European Journal (2012), 18(26), 8076-8083, S8076/1-S8076/44, database is CAplus and MEDLINE.

The authors demonstrated a family of diamondoid metal-organic frameworks (MOFs) based on functionalized mol. building blocks (pentanuclear zinc benzotriazolate clusters) and length-adjustable tetracarboxylate organic linkers by using a stepwise synthesis strategy. The authors have successfully achieved not only design and control to synthesize MOFs, but also the functionalization of both secondary building units (SBUs) and organic linkers in the same MOF for the first time. Also, the results of N₂ and H₂ adsorption show that their surface areas and H₂ uptake capacities are determined by the most optimal combination of functional groups from SBUs and organic linkers, interpenetration, and free volume in this system. A member of this series, DMOF-6 exhibits the highest surface area and H₂ adsorption capacity among this family of MOFs.

Chemistry – A European Journal published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C15H14O3, HPLC of Formula: 50670-76-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zhao, Wei published the artcileEffects of guanidinoacetic acid and complex antioxidant supplementation on growth performance, meat quality, and antioxidant function of broiler chickens, Synthetic Route of 121-79-9, the publication is Journal of the Science of Food and Agriculture (2021), 101(9), 3961-3968, database is CAplus and MEDLINE.

This study was conducted to evaluate the effects of adding guanidinoacetic acid (GAA), or complex antioxidant (CA), or their combination, in diets on the growth performance, carcass traits, meat quality, and antioxidant capacity of broilers. A total of 192 25-day-old broilers were assigned to a 2 × 2 factorial design including two dietary supplements at two different levels, in which the main effects were the addition of GAA (0 or 600 mg kg^-1) and CA (0 or 150 mg kg^-1). This trial lasted for 18 days. Compared with the control group, the GAA group, CA group, and GAA + CA group, decreased feed conversion ratio by 7.02%, 6.58%, and 11.40%, resp. Guanidinoacetic supplementation increased eviscerated yield, pH_24h (P < 0.05). Complex antioxidant supplementation increased the a* values (P < 0.05). The combination of GAA and CA did not affect the carcass traits and meat quality. Guanidinoacetic acid alone and CA alone and combined with GAA and CA decreased the reactive oxygen species (ROS) level and malonaldehyde (MDA) content (P < 0.05), and the GAA + CA group had the lowest ROS level and MDA content of broilers. Dietary supplementation of GAA, CA or their combination had beneficial effects on growth performance and breast antioxidant capacity, and the combination of GAA and CA could exert a synergistic effect in improving antioxidant capacity.

Journal of the Science of Food and Agriculture published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C15H23BO2, Synthetic Route of 121-79-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zhang, Feihong published the artcileInhibitory effect of antioxidants on biodiesel crystallization: Revealing the role of antioxidants, Computed Properties of 121-79-9, the publication is Fuel (2021), 120782, database is CAplus.

Effect of six antioxidants (butylated hydroxytoluene, Bu hydroxyanisole, di-tert-butylhydroquinone, tert-Bu hydroquinone, Pr gallate, and pyrogallic acid) on crystallization properties of biodiesel was systematically investigated. Results showed that all the six antioxidants effectively inhibited biodiesel crystallization at low temperatures as reflected by the decrease of cold filter plugging point by 1 ∼ 3°C, solid fat content by 0.01 ∼ 2.30%, crystallization rate from 10^-4 to 10^-5 ∼ 10^-6 k/min, crystal size from 214 x 14 ∼ 357 x 43 to 71 x 14 ∼ 286 x 29 (length x width, μm x μm), the absolute values of crystallization enthalpy changes by 1.5 ∼ 5.5 J/g. The min. concentrations of antioxidants for biodiesel to reach the induction period (8 h) regulated by the European Union standard were 500 mg/kg for TBHQ, PG, and PY, 1000 mg/kg for BHA and DBHQ, and 2000 mg/kg for BHT, resp. Antioxidants were inserted between initial crystal nucleuses through hydrogen bonds. The large steric hindrance of antioxidants inhibited the clustering of initial crystal nucleuses, thus inhibiting the growth of Me ester crystals. Biodiesel with the six antioxidants all had the same crystalline form (two-dimensional flake crystals). The weaker inhibitory effect of BHA than the other five antioxidants which didn’t present significant difference in inhibiting biodiesel crystallization was because the methoxy group of BHA cannot form a hydrogen bond well with the carbonyl group of Me ester mol.

Fuel published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C13H9FO, Computed Properties of 121-79-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Spittler, Terry D. published the artcileBiorational control of crop pests by mating disruption. Residue analyses of Z-9-dodecen-1-yl acetate and Z-11-tetradecen-1-yl acetate in grapes, Category: esters-buliding-blocks, the publication is ACS Symposium Series (1988), 430-6, database is CAplus.

(Z)-9-Dodecen-1-yl acetate (I) and (Z)-11-tetradecen-1-yl acetate (II), primary components of grape berry moth pheromone, were applied in vineyards via tie-on dispensers for the entire growing season. Mature grapes (100 g) were blended and extracted with acetone; following the addition of water, the analytes were extracted into hexane which, after evaporation, was adsorbed onto a Florisil Sep-pak. Elution was with 10% acetone in hexane. Chromatog. was on a Supelcowax 10 capillary column with temperature programming from 80 to 130° at 5°/min then 130 to 200 at 4°/min with a hold 9 min. Detection by HP-MSD Model #5970B was in the selective ion mode at 166 m/e and 194 m/e for I and II, resp. Corresponding retention times were 17.7 and 22.7 min. The sensitivity was <5 ppb for both materials at 80% recovery. Insect control by this biotech. approach was good, and it eliminated the use of traditional chem. pesticides against grape berry moth. No residues were detected in grape berries.

ACS Symposium Series published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C9H6BrNO2, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Xu, Zu-Sheng published the artcileAzobenzene-Assisted Alignment of Ferroelectric Liquid Crystals in the Chiral Smectic C Phase with an Alternating Current Field, Computed Properties of 50670-76-3, the publication is Chemistry of Materials (1998), 10(11), 3269-3271, database is CAplus.

An unexpected phenomenon of aligning ferroelec. liquid crystal (FLC) directly in the SmC* phase is observed relatively rapidly in the presence of an ac field, by doping a small amount of an azobenzene derivative into it. There may be some interaction s between the azo compound and the FLC mols. under the a.c. field. Interactions with the rubbed polyimide surface layer may also play a role. The preliminary results show that the kinetics of this azobenzene-assisted alignment depends on the concentration of azobenzene derivative The possibility of aligning FLC mols. in the SmC* phase relatively rapidly by doping with small amounts of azo compounds and by applying an a.c. field may have some useful applications, and it provides a fairly simple method for aligning FLCs.

Chemistry of Materials published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C7H10O4, Computed Properties of 50670-76-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Xu, Zu-Sheng published the artcileSynthesis and characterization of novel ferroelectric liquid crystals and copolymers containing biphenyl azobenzene and/or phenyl biphenyl carboxylate mesogenic groups, Formula: C15H14O3, the publication is Liquid Crystals (1999), 26(3), 351-359, database is CAplus.

Two new ferroelec. liquid crystals, 4-[(S)-1-(ethoxycarbonyl)]ethyl 4-[4′-(9-decenyloxy)biphenyl]azobenzoate (10) and its ester analog 4-[(S)-1-(ethoxycarbonyl)]ethyl {[4-(9-decenyloxy)]biphenyl-4′-yl}carbonyloxybenzoate (17), and side chain polysiloxane copolymers and terpolymers containing various amounts of 10 and 17 as mesogenic side groups have been synthesized. Their mesomorphic and phys. properties have been characterized. Both 10 and 17 exhibit isotropic, SmA*, SmC*, and Sm(I or F)* phases. The copolymer with 17 as the mesogenic group and terpolymers having low content of the azo compound 10 show a SmC* phase over a large temperature range down to room temperature The copolymer with the azo compound 10 as the mesogenic group is amorphous.

Liquid Crystals published new progress about 50670-76-3. 50670-76-3 belongs to esters-buliding-blocks, auxiliary class Benzene,Phenol,Ester, name is Ethyl 4′-hydroxy-[1,1′-biphenyl]-4-carboxylate, and the molecular formula is C16H18Br2ClN3O3, Formula: C15H14O3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Nudelman, Abraham published the artcileThe Role of Intracellularly Released Formaldehyde and Butyric Acid in the Anticancer Activity of Acyloxyalkyl Esters, SDS of cas: 122110-53-6, the publication is Journal of Medicinal Chemistry (2005), 48(4), 1042-1054, database is CAplus and MEDLINE.

Previous studies described a family of anticancer histone deacetylase inhibitor prodrugs of formula Me(CH₂)₂COOCH(R)OR¹, which upon intracellular hydrolysis release acids and aldehydes. This study examines the mechanisms by which the prodrugs affect tumor cells and the contribution of the released aldehyde (formaldehyde or acetaldehyde) and acids to their anticancer activity. Type I prodrugs release 2 equiv of a carboxylic acid and 1 equiv of an aldehyde, and of Type II release 2 equiv of acids and 2 equiv of an aldehyde. SAR studied inhibition of proliferation, induction of differentiation and apoptosis, histone acetylation, and gene expression. Formaldehyde, measured intracellularly, was the dominant factor affecting proliferation and cell death. Among the released acids, butyric acid elicited the greatest antiproliferative activity, but the nature of the acid had minor impact on proliferation. In HL-60 cells, formaldehyde-releasing prodrugs significantly increased apoptosis. The prodrugs affected to a similar extent the wild-type HL-60 and MES-SA cell lines and their multidrug-resistant HL-60/MX2 and MES-Dx5 subclones. In a cell-free histone deacetylase (HDAC) inhibition-assay only butyric acid inhibited HDAC activity. The butyric acid and formaldehyde induced cell differentiation and increased p53 and p21 levels, suggesting that both affect cancer cells, the acid by inhibiting HDAC and the aldehyde by an as yet unknown mechanism.

Journal of Medicinal Chemistry published new progress about 122110-53-6. 122110-53-6 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester,Inhibitor, name is (Pivaloyloxy)methyl butyrate, and the molecular formula is C10H18O4, SDS of cas: 122110-53-6.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics