Tag: M.W=200-250

Mouri, Emiko published the artcileAssociation behaviors of poly(N-vinylpyrrolidone)-grafted fullerenes in aqueous solution, Application In Synthesis of 3052-61-7, the publication is Journal of Polymer Research (2018), 25(10), 1-10, database is CAplus.

Poly(N-vinylpyrrolidone) (PVP)-grafted fullerenes (PVP-C₆₀ and PVP-C₇₀) were synthesized by iniferter polymerization in order to fabricate water-soluble fullerene containing micelles. PVP-C₆₀ formed micelles with hydrodynamic diameters ranging from 15 to 33 nm. The solubilization of fullerene mols. into the core of the PVP-C₆₀ micelles was also found to control the size of the micelles. By increasing the amount of added fullerene, we gradually increased the micelle size before drastically increasing it to that of 200 nm in hydrodynamic diameter The drastic change occurred at a critical value of the added C₆₀/PVP monomer ratio, almost independently of the mol. weight of PVP.

Journal of Polymer Research published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, Application In Synthesis of 3052-61-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Maruyama, Taiki published the artcileMultifunctional 3D Printing of Heterogeneous Polymer Structures by Laser-Scanning Micro-Stereolithography Using Reversible Addition-Fragmentation Chain-Transfer Polymerization, HPLC of Formula: 3052-61-7, the publication is ACS Applied Polymer Materials (2022), 4(8), 5514-5522, database is CAplus.

Stereolithog. is the most precise three-dimensional (3D) printing technol. and has been applied to various applications with various photocurable materials. However, most 3D-printed objects produced using conventional methods are made of uniform materials, limiting their functions. In this study, to produce heterogeneous 3D-printed objects, microphase-separated structures were controlled by the copolymerization of a photoinduced macro-reversible addition-fragmentation chain-transfer (macro-RAFT) agent and a monomer at different scanning speeds of an UV laser beam using a laboratory-constructed laser-scanning micro-stereolithog. system based on a bottom-up configuration in a fully open-to-air system. First, we demonstrated 3D printing using a RAFT agent by fabricating a pyramidal structure using a 375 nm laser. Copolymerization with styrene was performed to confirm that the synthesized poly(Bu acrylate) with dormant species at the end (DTC-PBA) formed block polymers upon photoirradiation NMR and gel permeation chromatog. (GPC) results indicated the formation of a block polymer. A homogeneous photocurable resin was prepared by mixing the synthesized DTC-PBA with multi-functional monomers, and 3D printing was performed using the prepared photocurable resin at different scanning speeds. As the scanning speed increased, the transparency of the 3D-printed model increased, whereas the mech. strength decreased. It was suggested from scanning probe microscopy (SPM) observations that these differences were due to differences in the microphase-separation structure. As a result, it was demonstrated that heterogeneous 3D structures with sites have different mech. and optical properties from those of a single material. Controlling the phys. properties of 3D-printed parts by controlling the laser irradiation conditions is useful for functionalizing 3D-printed microdevices.

ACS Applied Polymer Materials published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, HPLC of Formula: 3052-61-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Carrillo-Varela, Isabel published the artcileMethylene blue adsorption onto hydrogels made from different Eucalyptus dissolving pulps, Related Products of esters-buliding-blocks, the publication is Cellulose (Dordrecht, Netherlands) (2022), 29(1), 445-468, database is CAplus.

Bleached kraft pulp from Eucalyptus benthamii, E. globulus and E. nitens was purified via cold caustic extraction (CCE) with 5% and 10% (w/v) NaOH and activated with dilute acid hydrolysis (samples were coded as CCE5-H and CCE10-H, resp.) to produce dissolving-grade pulp. Hydrogels from CCE5-H and CCE10-H pulps were fabricated through the N-methylmorpholine N-oxide route and tested for methylene blue (MB) adsorption. The morphol., fiber biometry, mol. and supramol. structure, thermal stability and swelling capacity were also investigated. A higher degree of crystallinity was observed for cellulose in CCE10-H hydrogels. CCE10-H hydrogels also resulted in denser structures with lower swelling than CCE5-H hydrogels. The exptl. data for MB adsorption were fitted better to the Langmuir model, which led to estimated maximum adsorption capacities of 36-51 mg/g for CCE5-H hydrogels and 27-33 mg/g for CCE10-H hydrogels. Regarding the Eucalyptus species, hydrogels fabricated from E. nitens exhibited the highest capacities for adsorption of MB. This was attributed to the lowest crystalline fractions and crystallite sizes, and the highest kink indexes and intrinsic viscosities of E. nitens dissolving pulps, which resulted in regenerated hydrogels with highest pore coverage and water absorption capacities, and better accessibility to MB particles.

Cellulose (Dordrecht, Netherlands) published new progress about 121-79-9. 121-79-9 belongs to esters-buliding-blocks, auxiliary class Natural product, name is Propyl 3,4,5-trihydroxybenzoate, and the molecular formula is C10H12O5, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Liu, Bao-yu published the artcileThe synthesis of camostat intermediate, Formula: C12H15NO4, the publication is Huaxue Shiji (2006), 28(6), 371-372, database is CAplus.

4-(2-(2-(Dimethylamino)-2-oxoethoxy)-2-oxoethyl)phenyl-4-aminobenzoate, the intermediate of camostat, was obtained at room temperature and normal pressure with dimethylamine as the starting materials through 4 reaction steps to reduce the nitro group with ammonium formate as the hydrogen donor and palladium as the catalyst. The structure has been confirmed by FT-IR and ¹HNMR spectra.

Huaxue Shiji published new progress about 59721-16-3. 59721-16-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Phenol,Ester,Amide, name is 2-(Dimethylamino)-2-oxoethyl 2-(4-hydroxyphenyl)acetate, and the molecular formula is C12H15NO4, Formula: C12H15NO4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Rabizadeh, E. published the artcilePivanex, a histone deacetylase inhibitor, induces changes in BCR-ABL expression and when combined with STI571, acts synergistically in a chronic myelocytic leukemia cell line, Computed Properties of 122110-53-6, the publication is Leukemia Research (2007), 31(8), 1115-1123, database is CAplus and MEDLINE.

Chronic myelogenous leukemia (CML) is associated with the high TK activity chimeric protein BCR-ABL, known to contribute to cell tumorigenicity, resistance to apoptosis and differentiation. STI571, the TK inhibitor, is the current treatment for CML. One possible approach to overcome STI571 resistance appearing in some cases, involves the combination of histone deacetylase inhibitors (HDI) and STI571. We demonstrated that in K562, the CML cell line, pivaloyloxymethyl butyrate (Pivanex)-induced apoptosis, differentiation and reduced BCR-ABL protein levels and that the combination of Pivanex with STI571 acted synergistically. These data suggest the possible benefit of combining this HDI with STI571 for treatment of CML.

Leukemia Research published new progress about 122110-53-6. 122110-53-6 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ester,Inhibitor, name is (Pivaloyloxy)methyl butyrate, and the molecular formula is C10H18O4, Computed Properties of 122110-53-6.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Chevrie, David published the artcileOxidation of dithiocarbamates and synthesis of a stable sulfine, Quality Control of 3052-61-7, the publication is Tetrahedron Letters (1998), 39(49), 8983-8986, database is CAplus.

Investigation of the oxidation reaction of various dithiocarbamates demonstrated that the corresponding sulfines (S-oxides) are formed. Though their stabilities are very moderate, a number of sulfines could be isolated and characterized. When left at ambient temperature they decomposed to thiolocarbamates and dithiocarbamates. The sulfines from secondary dithiocarbamates led to disulfides. With a sterically hindered aryl group present on the sulfur atom, a stable sulfine was prepared and its crystal structure was analyzed.

Tetrahedron Letters published new progress about 3052-61-7. 3052-61-7 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Amide, name is Benzyl diethylcarbamodithioate, and the molecular formula is C12H17NS2, Quality Control of 3052-61-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Pryde, David C. published the artcileThe discovery of potent small molecule activators of human STING, Name: Methyl 2-methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-carboxylate, the publication is European Journal of Medicinal Chemistry (2021), 112869, database is CAplus and MEDLINE.

The adaptor protein STING plays a major role in innate immune sensing of cytosolic nucleic acids, by triggering a robust interferon response. Despite the importance of this protein as a potential therapeutic target for serious unmet medical conditions including cancer and infectious disease there remains a paucity of STING ligands. Starting with a benzothiazinone series of weak STING activators (human EC₅₀ ∼10μM) we identified several chemotypes with sub-micromolar STING activity across all the major protein polymorphs. An example compound I, based on an oxindole core structure, demonstrated robust on-target functional activation of STING (human EC₅₀ 185 nM) in immortalized and primary cells and a cytokine induction fingerprint consistent with STING activation. Our study has identified several related series of potent small mol. human STING activators with potential to be developed as immunomodulatory therapeutics.

European Journal of Medicinal Chemistry published new progress about 179950-77-7. 179950-77-7 belongs to esters-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Ester,Amide, name is Methyl 2-methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-carboxylate, and the molecular formula is C11H11NO4, Name: Methyl 2-methyl-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazine-6-carboxylate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Hirai, Yoshio published the artcileSex pheromone of fall armyworm: laboratory evaluation of male responses and inhibition of mating by pheromone components, Name: (Z)-Dodec-9-en-1-yl acetate, the publication is Journal of Chemical Ecology (1982), 8(1), 267-73, database is CAplus and MEDLINE.

Two components of the fall armyworm, Spodoptera frugiperda, sex pheromone, (Z)-9-dodecen-1-ol acetate (DDA) [16974-11-1] and (Z)-9-tetradecen-1-ol (TDA) [35153-15-2] were tested alone and in combination to determine their effects on male sexual response and inhibition of mating in the laboratory The threshold response for armyworm males was lower for TDA than for DDA, and males responded to TDA over a wider range of dosages. Although TDA is not attractive to armyworm males in the field, this compound was highly effective in reducing mating under laboratory conditions.

Journal of Chemical Ecology published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Name: (Z)-Dodec-9-en-1-yl acetate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Dunkelblum, Ezra published the artcileChemical characterization and species specificity of sex pheromones of Plusiinae moths in Israel, Product Details of C14H26O2, the publication is Archives of Insect Biochemistry and Physiology (1993), 22(3-4), 413-24, database is CAplus.

The female sex pheromones of four sympatric Plusiinae species, Autographa gamma, Chrysodeixis chalcites, Cornutiplusia circumflexa, and Trichoplusia ni were investigated in Israel. The research concentrated on the behavioral reproductive isolation regulated by their sex pheromones. The chem. composition of the four sex pheromones was determined by anal. of pheromone gland extracts, and in addition entrained volatiles released from virgin female C. chalcites and T. ni were also analyzed. The pheromones of these latter two species were found to contain several components, among which Z7-12:Ac was the main one. The pheromone glands of A. gamma and C. circumflexa were found to contain relatively small amounts of material and only Z7-12:Ac and Z7-12:OH could be pos. identified. These two pheromone components were present in the two species in roughly inverse ratios. Whereas A. gamma utilizes Z7-12:Ac as the main or sole pheromone component, C. circumflexa requires both Z7-12:OH and Z7-12:Ac, with the alc. being predominant. This is the first reported Plusiinae species using Z7-12:OH as the main pheromone component. Behavioral studies in the wind tunnel and field tests indicate that females of each of the four Plusiinae species utilize a species-specific blend of chems., consisting of attractive and antagonistic components, to attract conspecific males. Such a complementary strategy provides improved behavioral reproductive isolation among the sympatric species. For example, Z5-12:Ac, which is a specific component of the T. ni sex pheromone, may be redundant as regards the attraction of T. ni males. However, addition of small amounts of this compound to pheromone blends of A. gamma and C. chalcites resulted in complete inhibition of the males’ flight behavior and trap catch; thus contributing significantly to the specificity of the T. ni sex pheromone. The relatively high proportion of Z7-12:OH in the sex pheromone of C. circumflexa, essential to the latter, is highly inhibitory to the three other Plusiinae species. The only case of cross-attraction occurred when T. ni males were attracted to a certain extent to A. gamma lures and females.

Archives of Insect Biochemistry and Physiology published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C14H26O2, Product Details of C14H26O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Smith, M. T. published the artcileHickory shuckworm Cydia caryana: electroantennogram and flight tunnel studies of potential sex pheromone components, Product Details of C14H26O2, the publication is Entomologia Experimentalis et Applicata (1987), 44(1), 23-30, database is CAplus.

Electroantennogram (EAG) measurements of male C. caryana moth antennal olfactory response to monounsaturated 12 and 14 carbon alcs. and acetates indicated that the (E)-8-, (E)-10-conjugated double bond system of a dodecadien-1-ol acetate is a critical chem. structural component of the C. caryana sex pheromone. Addnl., EAG measurements implicated (E)-8-dodecen-1-ol acetate, (Z)-8-dodecen-1-ol acetate, (Z)-9-dodecen-1-ol acetate, and (Z)-12-tetradecen-1-ol as potential minor pheromonal components. An EAG dosage-response study suggested that there were ≥2 heterologous populations of pheromone acceptors. Behavioral anal. of male moth response in a flight tunnel to compounds which evoked the stronger EAG responses suggested that (E,E)-8,10-dodecadien-1-ol acetate and (Z)-9-dodecen-1-ol acetate resemble or are C. caryana sex pheromonal components, while (Z)-8-dodecen-1-ol acetate and (E)-10-dodecen-1-ol acetate are either parapheromones or are minor pheromone components. Behavioral significance of (Z)-12-tetradecen-1-ol was difficult to interpret in the flight tunnel.

Entomologia Experimentalis et Applicata published new progress about 16974-11-1. 16974-11-1 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is (Z)-Dodec-9-en-1-yl acetate, and the molecular formula is C16H24BF4Ir, Product Details of C14H26O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics