Tag: M.W=150-200

Application In Synthesis of Methyl 3-phenylpropionate. I found the field of Chemistry very interesting. Saw the article Catalytic asymmetric synthesis of 2,5-dihydrofurans using synergistic bifunctional Ag catalysis published in 2019.0, Reprint Addresses Chapman, E (corresponding author), Univ Arizona, Coll Pharm, Dept Pharmacol & Toxicol, Tucson, AZ 85721 USA.; Hu, WH (corresponding author), Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou, Guangdong, Peoples R China.. The CAS is 103-25-3. Through research, I have a further understanding and discovery of Methyl 3-phenylpropionate.

We report a bifunctional Ag catalyst promoted intramolecular capture of oxonium ylides with alkynes for the enantioselective synthesis of 2,5-dihydrofurans. This represents unprecedented synergistic catalysis of a bifunctional Ag catalyst. Mechanistic studies revealed that [(R)-3,5-DM-BINAP](AgSbF6)(2) (9) is likely to be the active catalytic species and that the reaction involves second order kinetics with respect to 9, suggesting that two molecules of 9 are involved in the intramolecular trapping of a Ag-associated oxonium ylide with a Ag-activated alkyne. Based on our mechanistic hypothesis, we further optimized the reaction, rendering a facile approach to 2,5-dihydrofurans in good to excellent yields in a highly chemo- and enantioselective fashion.

Application In Synthesis of Methyl 3-phenylpropionate. About Methyl 3-phenylpropionate, If you have any questions, you can contact Shi, TD; Teng, SH; Reddy, AGK; Guo, X; Zhang, YT; Moore, KT; Buckley, T; Mason, DJ; Wang, W; Chapman, E; Hu, WH or concate me.

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pan, C; Wang, LM; Han, JW in [Pan, Cheng; Wang, Limin; Han, Jianwei] East China Univ Sci & Technol, Key Lab Adv Mat, Inst Fine Chem, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China; [Pan, Cheng; Wang, Limin; Han, Jianwei] East China Univ Sci & Technol, Feringa Nobel Prize Scientist Joint Res Ctr, Inst Fine Chem, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China; [Han, Jianwei] Chinese Acad Sci, Shanghai Hong Kong Joint Lab Chem Synth, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China published Palladium-Catalyzed Site-Selective Benzocylization of Aromatic Acids with o-Fluoro-Substituted Diaryliodonium Salts toward 3,4-Benzocoumarins in 2020.0, Cited 68.0. Application In Synthesis of 6H-Benzo[c]chromen-6-one. The Name is 6H-Benzo[c]chromen-6-one. Through research, I have a further understanding and discovery of 2005-10-9.

By using 2-fluoro-substituted diaryliodonium salts, a novel benzocylization has been accomplished for the synthesis of 3,4-benzocoumarin derivatives via a cascade of ortho-arylation and defluorination in the presence of palladium catalysts. The reaction exhibits a broad compatibility of readily available aromatic acids with an excellent level of site-selectivity. Mechanistic investigations revealed a unique reactivity of carboxylic acid directed arylation by followed nucleophilic substitution of aromatic fluoride in the present system.

About 6H-Benzo[c]chromen-6-one, If you have any questions, you can contact Pan, C; Wang, LM; Han, JW or concate me.. Application In Synthesis of 6H-Benzo[c]chromen-6-one

Reference:
Article; Zhang, Jian; Shi, Dongdong; Zhang, Haifeng; Xu, Zheng; Bao, Hanyang; Jin, Hongwei; Liu, Yunkui; Tetrahedron; vol. 73; 2; (2017); p. 154 – 163;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article Application of the Movable Type Free Energy Method to the Caspase-Inhibitor Binding Affinity Study WOS:000494798300191 published article about ALZHEIMERS-DISEASE; NEUROFIBRILLARY TANGLES; MOLECULAR DOCKING; HUMAN NEURONS; TAU; CLEAVAGE; PROTEIN; ACTIVATION; APOPTOSIS; DEGENERATION in [Xue, Song] Zhongnan Univ Law & Econ, Sch Stat & Math, Wuhan 430073, Hubei, Peoples R China; [Liu, Hao] Wuhan Univ Technol, Sch Mech & Elect Engn, Wuhan 430070, Hubei, Peoples R China; [Zheng, Zheng] Wuhan Univ Technol, Sch Chem Chem Engn & Life Sci, Wuhan 430070, Hubei, Peoples R China in 2019.0, Cited 57.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4. Category: esters-buliding-blocks

Many studies have provided evidence suggesting that caspases not only contribute to the neurodegeneration associated with Alzheimer’s disease (AD) but also play essential roles in promoting the underlying pathology of this disease. Studies regarding the caspase inhibition draw researchers’ attention through time due to its therapeutic value in the treatment of AD. In this work, we apply the Movable Type (MT) free energy method, a Monte Carlo sampling method extrapolating the binding free energy by simulating the partition functions for both free-state and bound-state protein and ligand configurations, to the caspase-inhibitor binding affinity study. Two test benchmarks are introduced to examine the robustness and sensitivity of the MT method concerning the caspase inhibition complexing. The first benchmark employs a large-scale test set including more than a hundred active inhibitors binding to caspase-3. The second benchmark includes several smaller test sets studying the relative binding free energy differences for minor structural changes at the caspase-inhibitor interaction interfaces. Calculation results show that the RMS errors for all test sets are below 1.5 kcal/mol compared to the experimental binding affinity values, demonstrating good performance in simulating the caspase-inhibitor complexing. For better understanding the protein-ligand interaction mechanism, we then take a closer look at the global minimum binding modes and free-state ligand conformations to study two pairs of caspase-inhibitor complexes with (1) different caspase targets binding to the same inhibitor, and (2) different polypeptide inhibitors targeting the same caspase target. By comparing the contact maps at the binding site of different complexes, we revealed how small structural changes affect the caspase-inhibitor interaction energies. Overall, this work provides a new free energy approach for studying the caspase inhibition, with structural insight revealed for both free-state and bound-state molecular configurations.

About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Xue, S; Liu, H; Zheng, Z or concate me.. Category: esters-buliding-blocks

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article Cobalt-catalysed selective synthesis of aldehydes and alcohols from esters WOS:000544773800026 published article about CARBOXYLIC-ACIDS; REDUCTION; EFFICIENT; CARBONYL; HYDROSILYLATION; HYDROGENATION; HYDROBORATION; COMPLEXES; LIGAND; MILD in [Pattanaik, Sandip; Chidambaram, Gunanathan] HBNI, Natl Inst Sci Educ & Res NISER, Sch Chem Sci, Bhubaneswar 752050, Khurda, India in 2020.0, Cited 51.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4. HPLC of Formula: C10H10O2

Efficient and selective reduction of esters to aldehydes and alcohols is reported in which a simple cobalt pincer catalyst catalyses both transformations using diethylsilane as a reductant. Remarkably, the reaction selectivity is controlled by the stoichiometry of diethylsilane.

About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Pattanaik, S; Chidambaram, G or concate me.. HPLC of Formula: C10H10O2

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article Electronic Cigarette Refill Fluids Sold Worldwide: Flavor Chemical Composition, Toxicity, and Hazard Analysis WOS:000602573000009 published article about SAFETY ASSESSMENT; LIQUIDS; IDENTIFICATION; FORMALDEHYDE; TOXICANTS; VAPORS in [Omaiye, Esther E.] Univ Calif Riverside, Environm Toxicol Grad Program, Riverside, CA 92521 USA; [Omaiye, Esther E.; Talbot, Prue] Univ Calif Riverside, Dept Mol Cell & Syst Biol, Riverside, CA 92521 USA; [Luo, Wentai; McWhirter, Kevin J.; Pankow, James F.] Portland State Univ, Dept Civil & Environm Engn, Portland, OR 97201 USA; [Luo, Wentai; Pankow, James F.] Portland State Univ, Dept Chem, Portland, OR 97201 USA in 2020.0, Cited 72.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4. Safety of Methyl 3-phenyl-2-propenoate

Flavor chemicals in electronic cigarette (EC) fluids, which may negatively impact human health, have been studied in a limited number of countries/locations. To gain an understanding of how the composition and concentrations of flavor chemicals in ECs are influenced by product sale location, we evaluated refill fluids manufactured by one company (Bitchy LTD) and purchased worldwide. Flavor chemicals were identified and quantified using gas chromatography/mass spectrometry (GC/MS). We then screened the fluids for their effects on cytotoxicity (MTT assay) and proliferation (live-cell imaging) and tested authentic standards of specific flavor chemicals to identify those that were cytotoxic at concentrations found in refill fluids. A total of 126 flavor chemicals were detected in 103 bottles of refill fluid, and their number per/bottle ranged from 1-50 based on our target list. Two products had none of the flavor chemicals on our target list, nor did they have any nontargeted flavor chemicals. A total of 28 flavor chemicals were present at concentrations >= 1 mg/mL in at least one product, and 6 of these were present at concentrations >= 10 mg/mL. The total flavor chemical concentration was >= 1 mg/mL in 70% of the refill fluids and >= 10 mg/mL in 26%. For sub-brand duplicate bottles purchased in different countries, flavor chemical concentrations were similar and induced similar responses in the in vitro assays (cytotoxicity and cell growth inhibition). The levels of furaneol, benzyl alcohol, ethyl maltol, ethyl vanillin, corylone, and vanillin were significantly correlated with cytotoxicity. The margin of exposure calculations showed that pulegone and estragole levels were high enough in some products to present a nontrivial calculated risk for cancer. Flavor chemical concentrations in refill fluids often exceeded concentrations permitted in other consumer products. These data support the regulation of flavor chemicals in EC products to reduce their potential for producing both cancer and noncancer toxicological effects.

Safety of Methyl 3-phenyl-2-propenoate. About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Omaiye, EE; Luo, WT; McWhirter, KJ; Pankow, JF; Talbot, P or concate me.

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article A Bipyridine-Palladium Derivative as General Pre-Catalyst for Cross-Coupling Reactions in Deep Eutectic Solvents WOS:000476320300001 published article about SONOGASHIRA COUPLINGS; PD; EFFICIENT; SYSTEM in [Saavedra, Beatriz; Gonzalez-Gallardo, Nerea; Meli, Alessandro; Ramon, Diego J.] Univ Alicante, Fac Ciencias, Dept Quim Organ, Apdo 99, Alicante 03080, Spain; [Saavedra, Beatriz; Gonzalez-Gallardo, Nerea; Meli, Alessandro; Ramon, Diego J.] Univ Alicante, Fac Ciencias, ISO, Apdo 99, E-03080 Alicante, Spain; [Meli, Alessandro] Univ Palermo, Dipartimento Sci Biol Chim & Farmaceut, Viale Sci,Ed 17, I-90128 Palermo, Italy in 2019.0, Cited 34.0. Name: Methyl 3-phenyl-2-propenoate. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4

A versatile and DES-compatible bipyridine palladium complex has been developed as a general pre-catalyst for different cross-coupling reactions (Hiyama, Suzuki-Miyaura, Heck-Mizoroki and Sonogashira) in deep eutectic solvents. Hydrogen bond capacity of the ligand allows to keep the excellent level of results previously obtained in classical organic solvents. Palladium pre-catalyst showed a high catalytic activity for many cross-coupling reactions, demonstrating a great versatility and applicability. Also, this methodology employs sustainable solvents as a reaction medium and highlights the potential of DES as alternative solvents in organometallic catalysis. The catalyst and DES were easily and successfully recycled. The formation of PdNPs in DES has been confirmed by TEM and XPS analysis and their role as catalyst by mercury test. The dynamic coordination of bipyridine-type ligand in the palladium complex formation has been studied via UV/Vis.

Name: Methyl 3-phenyl-2-propenoate. About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Saavedra, B; Gonzlez-Gallardo, N; Meli, A; Ramn, DJ or concate me.

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recently I am researching about N-HETEROCYCLIC CARBENE; SELECTIVE HYDROGENATION; CONJUGATE REDUCTION; HIGHLY EFFICIENT; OXIDE CATALYSTS; COMPLEXES; KETONES; LOUREIRIN; ALDEHYDES; NITROARENES, Saw an article supported by the Qingdao Institute of Bioenergy and Bioprocess Technology (QIBEBT), Chinese Academy of Sciences [Y6710619KL]; 13th-Five Key Project of the Chinese Academy of Sciences [Y7720519KL]; Royal Society-Newton Advanced Fellowship [NAF-R2-180695]. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Song, T; Ma, ZM; Yang, Y. The CAS is 103-26-4. Through research, I have a further understanding and discovery of Methyl 3-phenyl-2-propenoate. Computed Properties of C10H10O2

Herein, we report highly chemoselective hydrogenation of alpha,beta-unsaturated carbonyls to saturated carbonyls catalyzed by cobalt nanoparticles supported on the biomass-derived carbon from bamboo shoots with molecular hydrogen in water, which is the first prototype using a heterogeneous non-noble metal catalyst for such organic transformation as far as we know. The optimal cobalt nanocatalyst, CoOx@NC-800, manifested remarkable activity and selectivity for hydrogenation of C=C in alpha,beta-unsaturated carbonyls under mild conditions. A broad set of alpha,beta-aromatic and aliphatic unsaturated carbonyls were selectively reduced to their corresponding saturated carbonyls in up to 99 % yields with good tolerance of various functional groups. Meanwhile, a new straightforward one-pot cascade synthesis of saturated carbonyls was realized with high activity and selectivity via the cross-aldol condensation of ketones with aldehydes followed by selective hydrogenation. More importantly, this one-pot strategy is applicable for the expedient synthesis of Loureirin A, a versatile bioactive and medicinal molecule, from readily available starting materials, further highlighting the practical utility of the catalyst. In addition, the catalyst can be easily separated for successive reuses without significant loss in both activity and selectivity.

Computed Properties of C10H10O2. About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Song, T; Ma, ZM; Yang, Y or concate me.

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Synthesis of pyrazolo- and [1,2,4]triazolo-[1,5-a]quinolin-9-ols by cycloaddition to 8-hydroxyquinoline N-imide published in 2019.0. Name: Methyl 3-phenyl-2-propenoate, Reprint Addresses Vorob’ev, AY (corresponding author), Russian Acad Sci, Siberian Branch, NN Vorozhtsov Novosibirsk Inst Organ Chem, 9 Akad Lavrentieva Ave, Novosibirsk 630090, Russia.; Vorob’ev, AY (corresponding author), Novosibirsk State Univ, 1 Pirogova St, Novosibirsk 630090, Russia.. The CAS is 103-26-4. Through research, I have a further understanding and discovery of Methyl 3-phenyl-2-propenoate

The reaction of 1-amino-8-hydroxyquinolinium mesitylenesulfonate with alkenes and alkynes containing electron-withdrawing substituents was performed in MeCN-K2C?(3) system and gave the respective 9-hydroxypyrazolo[1,5-a]quinolines. The reaction with acetonitrile and aromatic nitriles in aqueous 2 N K?H solution gave the respective 2-substituted 9-hydroxy[1,2,4]triazolo[1,5-a]quinolines.

Name: Methyl 3-phenyl-2-propenoate. About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Evtushok, VE; Vorob’ev, AY or concate me.

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article Cobalt-molybdenum co-catalyst for heterogeneous photocatalytic H-mediated transformations WOS:000497249700004 published article about HYDROGEN EVOLUTION REACTION; ALKYNE SEMIHYDROGENATION; CATALYST; MOS2; SELECTIVITY; ALKENES; ISOMERIZATION; GENERATION; NICKEL; SPIN in [Scaiano, Juan C.; Lanterna, Anabel E.] Univ Ottawa, Dept Chem & Biomol Sci, 10 Marie Curie, Ottawa, ON K1N 6N5, Canada; Univ Ottawa, Ctr Adv Mat Res CAMaR, 10 Marie Curie, Ottawa, ON K1N 6N5, Canada in 2019.0, Cited 43.0. Computed Properties of C10H10O2. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4

Earth abundant materials, Mo and Co, are used to decorate TiO2 and work as co-catalyst for the selective semi-hydrogenation of alkynes and isomerization of estragole in a H-2-free environment under UVA irradiation. Catalytic efficiency is higher than highly-reactive Pd-decorated TiO2, using lower metal loadings and showing better selectivity towards the semi-hydrogenation reaction. (C) 2019 Elsevier Inc. All rights reserved.

Computed Properties of C10H10O2. About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Wang, BW; Duke, K; Scaiano, JC; Lanterna, AE or concate me.

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article Chemoselective transfer hydrogenation of alpha,beta-unsaturated carbonyls catalyzed by a reusable supported Pd nanoparticles on biomass-derived carbon WOS:000458222300017 published article about ASYMMETRIC TRANSFER HYDROGENATION; N-HETEROCYCLIC CARBENE; HIGHLY EFFICIENT; COMPLEXES; KETONES; RUTHENIUM; NITROARENES; REDUCTION; IRIDIUM; RHODIUM in [Song, Tao; Duan, Yanan; Yang, Yong] Chinese Acad Sci, Qingdao Inst Bioenergy & Bioproc Technol, CAS Key Lab Biobased Mat, Qingdao 266101, Peoples R China in 2019.0, Cited 36.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4. Recommanded Product: 103-26-4

We herein report highly chemoselective transfer hydrogenation of alpha,beta-unsaturated carbonyl compounds to saturated carbonyls with formic acid as a hydrogen donor over a stable and recyclable heterogeneous Pd nano particles (NPs) on N,O-dual doped hierarchical porous biomass-derived carbon. The synergistic effect between Pd NPs and incorporated heteroatoms on carbon plays a critical role on promoting the reaction efficiency. A series of alpha,beta-aromatic and aliphatic unsaturated carbonyl compounds was selectively reduced to their corresponding saturated carbonyls in up to 97% isolated yields with good tolerance of various functional groups. In addition, the catalyst can be successively reused for at least 6 times without significant loss in reaction efficiency.

Recommanded Product: 103-26-4. About Methyl 3-phenyl-2-propenoate, If you have any questions, you can contact Song, T; Duan, YA; Yang, Y or concate me.

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics