Tag: M.W=150-200

Goebel, Dominik published the artcileSubstitution Effect on 2-(Oxazolinyl)-phenols and 1,2,5-Chalcogenadiazole-Annulated Derivatives: Emission Color-Tunable, Minimalistic Excited-State Intramolecular Proton Transfer (ESIPT)-based Luminophores, SDS of cas: 1877-71-0, the publication is Journal of Organic Chemistry (2021), 86(21), 14333-14355, database is CAplus and MEDLINE.

Minimalistic 2-(oxazolinyl)-phenols substituted with different electron-donating and -withdrawing groups as well as 1,2,5-chalcogenadiazole-annulated derivatives thereof were synthesized and investigated toward their emission behavior in solution as well as in the solid state. Depending on the nature of the incorporated substituent and its position, emission efficiencies were increased or diminished, resulting in AIE- or ACQ-characteristics. Single crystal anal. revealed J- and H-type packing motifs and a so far undescribed isolation of ESIPT-based fluorophores in the keto form.

Journal of Organic Chemistry published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C9H8O4, SDS of cas: 1877-71-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Sim, Jeongwoo published the artcileElectrochemical C(sp³)-H Functionalization of γ-Lactams Based on Hydrogen Atom Transfer, HPLC of Formula: 103-26-4, the publication is Organic Letters (2022), 24(23), 4264-4269, database is CAplus and MEDLINE.

The electrochem. α-amidoalkylation of γ-lactams based on transition-metal-free cross-coupling via hydrogen atom transfer was described. The highly selective hydrogen atom transfer process allows for a broad substrate scope including both inter- and intramol. reactions. Also, the construction of quaternary centers was realized by a double hydrogen atom transfer protocol to afford spirocycles. Detailed mechanistic studies including exptl. and computational studies are provided to support the reaction pathway.

Organic Letters published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C10H10O2, HPLC of Formula: 103-26-4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Sendra, M. published the artcileImmune-responsive gene 1 (IRG1) and dimethyl itaconate are involved in the mussel immune response, Recommanded Product: Dimethyl itaconate, the publication is Fish & Shellfish Immunology (2020), 645-655, database is CAplus and MEDLINE.

Immune-responsive gene 1 (irg1) is a gene that is well-conserved among different taxa and is highly expressed in the mussel Mytilus galloprovincialis at the constitutive level. The expression of this gene increases after a bacterial infection, primarily in haemocytes. Irg1 catalyzes the production of itaconic acid from cis-aconitic acid in the Krebs cycle. Recently, itaconate has been revealed as an immune metabolite involved in macrophage polarization. In this work, we studied the effects of exogenous di-Me itaconate (DI) on mussels in vitro and in vivo at relevant previously described endogenous concentrations and in mussels infected with Vibrio splendidus. DI did not have adverse effects on the haemocytes viability, apoptotic cells, proliferation and phagocytic activity; however, haemocyte size, velocity and accumulated distance were decreased. The antibacterial activity of DI in vitro and in vivo was observed with high concentrations of DI, i.e., 30 and 50 mM, resp. Furthermore, DI inhibited total ROS, increased mitochondrial ROS and modulated antioxidant genes, such as SOD and CAT, related to Nrf2 activation. In this research, we have demonstrated some important pathways in haemocytes in which itaconate can be involved after its production in a bacterial infection.

Fish & Shellfish Immunology published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C16H24BF4Ir, Recommanded Product: Dimethyl itaconate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Benini, Celine published the artcileVariations in the essential oils from ylang-ylang (Cananga odorata [Lam.] Hook f. & Thomson forma genuina) in the Western Indian Ocean islands, Product Details of C12H14O2, the publication is Flavour and Fragrance Journal (2012), 27(5), 356-366, database is CAplus.

Ylang-ylang essential oil is an important raw material for the fragrance industry. Despite its economic importance, to the best of our knowledge, no study has yet been undertaken to assess the chem. polymorphism of the different production areas. This underestimated variability is an interesting source of raw material for perfumers. That is why the variation in the chem. composition of four fractions of the essential oils extracted from Cananga odorata, grown in four locations Grande Comore, Mayotte, Nossi Be and Ambanja, was studied. A total of 119 compounds, representing 85.7-96.4% of the total essential oil composition, were identified using gas chromatog.-mass spectrometry and quantified by gas chromatog. with a flame ionization detector. Thirty-two compounds previously unreported in ylang-ylang essential oil were identified. The distinction between the Comoros and Madagascar groups was made on the basis of the chem. classes. It was possible to significantly distinguish the Grande Comore and Mayotte essential oil samples, as well as the Ambanja and Nossi Be essential oil samples, on the basis of their main compounds The aromatic compounds profile for the origin of each essential oil fraction was established. Regression trees were built, allowing the provenance of the essential oils prepared at the laboratory level to be easily differentiated on the basis of a limited number of major compounds Copyright © 2012 John Wiley & Sons, Ltd.

Flavour and Fragrance Journal published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C12H14O2, Product Details of C12H14O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Aprile, Silvio published the artcile1,2,4-Oxadiazole-Bearing Pyrazoles as Metabolically Stable Modulators of Store-Operated Calcium Entry, Computed Properties of 1877-71-0, the publication is ACS Medicinal Chemistry Letters (2021), 12(4), 640-646, database is CAplus and MEDLINE.

Store-operated calcium entry (SOCE) is a pivotal mechanism in calcium homeostasis, and, despite still being under investigation, its dysregulation is known to be associated with severe human disorders. SOCE modulators are therefore needed both as chem. probes and as therapeutic agents. While many small mols. have been described so far, their poor properties in terms of drug-likeness have limited their translation into the clin. practice. In this work, we describe the bioisosteric replacement of the ester moiety in pyrazole derivatives with a 1,2,4-oxadiazole ring as a means to afford a class of modulators with high metabolic stability. Moreover, among our derivatives, a compound able to increase the calcium entry was identified, further enriching the library of available SOCE activators.

ACS Medicinal Chemistry Letters published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C9H8O4, Computed Properties of 1877-71-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Dong, Xichang published the artcileMerging shuttle reactions and paired electrolysis for reversible vicinal dihalogenations, Synthetic Route of 5205-11-8, the publication is Science (Washington, DC, United States) (2021), 371(6528), 507-514, database is CAplus and MEDLINE.

Vicinal dibromides and dichlorides are important commodity chems. and indispensable synthetic intermediates in modern chem. that are traditionally synthesized using hazardous elemental chlorine and bromine. Meanwhile, the environmental persistence of halogenated pollutants necessitates improved approaches to accelerate their remediation. Here, we introduce an electrochem. assisted shuttle (e-shuttle) paradigm for the facile and scalable interconversion of alkenes and vicinal dihalides, a class of reactions that can be used both to synthesize useful dihalogenated mols. from simple alkenes and to recycle waste material through retro-dihalogenation. The reaction is demonstrated using 1,2-dibromoethane, as well as 1,1,1,2-tetrachloroethane or 1,2-dichloroethane, to dibrominate or dichlorinate, resp., a wide range of alkenes in a simple setup with inexpensive graphite electrodes. Conversely, the hexachlorinated persistent pollutant lindane could be fully dechlorinated to benzene in soil samples using simple alkene acceptors.

Science (Washington, DC, United States) published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C12H14O2, Synthetic Route of 5205-11-8.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Han, Li-Jun published the artcilePalladium-Catalyzed Methoxycarbonylation of 1,3-Butadiene to Methyl-3-Pentenoate: Introduction of a Continuous Process, Recommanded Product: Dimethyl adipate, the publication is Journal of Catalysis (2021), 283-290, database is CAplus.

The base-assisted Pd(cod)Cl₂/xantphos-catalyzed methoxycarbonylation of 1,3-butadiene (BD) to methyl-3-pentenoate (MP) was explored. Mechanistic studies suggested excessive xantphos (beyond an equimolar amount per Pd) as well as its substitute, pyridines of proper steric and electronic functionality, do participate catalytic cycle and significantly reduce activation energy by accelerating rate-limiting methanolysis step. As thus, all reaction parameters, especially solvents, were optimized based on Pd(cod)Cl₂/Xantphos/4-hexylpyridine catalytic system, enabling construction of a continuous process. Systematic optimization demonstrated that a yield of 82% of MP with a purity of 99.8% could be reached under steady-state operation.

Journal of Catalysis published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C8H14O4, Recommanded Product: Dimethyl adipate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Smart, M. C. published the artcileImproved performance of lithium-ion cells with the use of fluorinated carbonate-based electrolytes, Safety of Ethyl (2,2,2-trifluoroethyl) carbonate, the publication is Journal of Power Sources (2003), 359-367, database is CAplus.

There is increasing interest in developing Li-ion electrolytes that possess enhanced safety characteristics, while still able to provide the desired stability and performance. Toward this end, efforts were focused on the development of Li-ion electrolytes which contain partially and fully fluorinated carbonate solvents. The advantage of using such solvents is that they possess the requisite stability demonstrated by the hydrocarbon-based carbonates, while also possessing more desirable phys. properties imparted by the presence of the F substituents, such as lower m.ps., increased stability toward oxidation, and favorable SEI film forming characteristics on C. The beneficial effect of electrolytes which contain the following fluorinated carbonate-based solvents:Me-2,2,2-trifluoroethyl carbonate (MTFEC),Et-2,2,2-trifluoroethyl carbonate (ETFEC), propyl-2,2,2-trifluoroethyl carbonate (PTFEC),Me-2,2,2,2′,2′,2′-hexafluoro-CHMe₂ carbonate (MHFPC),Et-2,2,2,2′,2′,2′-hexafluoroCHMe₂ carbonate (EHFPC), and di-2,2,2-trifluoroethyl carbonate (DTFEC) was demonstrated. These solvents were incorporated into multi-component ternary and quaternary carbonate-based electrolytes and evaluated in Li-C and C-LiNi_0.8Co_0.2O₂ cells, with Li reference electrodes. In addition to determining the charge/discharge behavior of these cells, Tafel polarization measurements, linear polarization measurements, and electrochem. impedance spectroscopy were used to further characterize the performance of these electrolytes, including the SEI formation characteristics and Li intercalation/de-intercalation kinetics.

Journal of Power Sources published new progress about 156783-96-9. 156783-96-9 belongs to esters-buliding-blocks, auxiliary class Trifluoromethylated Building Blocks, name is Ethyl (2,2,2-trifluoroethyl) carbonate, and the molecular formula is C9H9N3, Safety of Ethyl (2,2,2-trifluoroethyl) carbonate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Bhattacharjee, Jayeeta published the artcileA highly efficient Ti-catalyst for the deoxygenative reduction of esters under ambient conditions: experimental and mechanistic insights from DFT studies, Product Details of C10H10O2, the publication is Dalton Transactions (2022), 51(15), 5859-5867, database is CAplus and MEDLINE.

Titanium(IV) phosphinous amide-borane chelate complexes I (1, 2; X = Cl, CH₂SiMe₃) were prepared as catalysts for deoxygenative reduction of carboxylic esters RCO₂R¹ with pinacolborane, affording benzyl borates RCH₂OBpin. In this paper, we report the synthesis of amidophosphineborane-supported titanium chloride 1 and alkyl complex 2 were prepared using a salt metathesis reaction. Ti^IV complex 1 was obtained by the reaction of the bis-borane ligand [{Ph₂P(BH₃)NH}₂C₆H₄] and TiCl₄ in toluene followed by the addition of 2 equiv of [LiN(SiMe₃)₂] at ambient temperature Ti^IV bis-alkyl complex 2 was isolated from the reaction of complex 1 with 2.5 equiv of LiCH₂SiMe₃ in toluene. The solid-state structure of complex 1 is established by single-crystal X-ray diffraction anal. Ti^IV bis-alkyl complex 2 has proved to be a competent catalyst in the deoxygenative reduction of aliphatic and aromatic esters with pinacolborane (HBpin) to afford corresponding boryl ethers at room temperature under solvent-free conditions. Catalyst 2 exhibits chemoselectivity toward ester functionalities over halides, heteroatoms, olefins, and amino functional groups. DFT studies demonstrate that the active form of catalyst 2 is capable of easily transferring its hydrides to ester substrates at room temperature The studies further reveal that the rate-limiting step (RLS) in an ester-to-boryl ether conversion is the cleavage of the C-O bond of an ester. In brief, the titanium-catalyzed ester-to-boryl ether conversions are found to be downhill processes having small activation barriers along all mechanistic steps.

Dalton Transactions published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C10H10O2, Product Details of C10H10O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Sharma, Gangavaram V. M. published the artcileA simple and efficient protocol for the deprenylation of ethers and esters catalyzed by zirconium(IV) chloride-sodium iodide, Formula: C12H14O2, the publication is Synlett (2003), 1728-1730, database is CAplus.

An efficient protocol for the deprotection of prenyl ethers and esters is developed using 20 mol% ZrCl₄-NaI (1:1) in CH₃CN as a reagent system. A variety of substrates as well as functional groups well tolerate the present reaction conditions.

Synlett published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C26H36N4O8, Formula: C12H14O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics