Tag: M.W=150-200

Authors Wang, YQ; Wang, SP; Chen, BJ; Li, MC; Hu, XQ; Hu, BX; Jin, LQ; Sun, N; Shen, ZL in GEORG THIEME VERLAG KG published article about CROSS-COUPLING REACTIONS; C-H LACTONIZATION; DEHYDROGENATIVE LACTONIZATION; BOND FUNCTIONALIZATION; PHOTOREDOX CATALYSIS; AEROBIC OXIDATION; CARBOXYLIC-ACIDS; SCHOLL REACTION; METAL-FREE; C(SP(2))-H in [Wang, Yiqing; Li, Meichao; Hu, Xinquan; Hu, Baoxiang; Jin, Liqun; Sun, Nan; Shen, Zhenlu] Zhejiang Univ Technol, Coll Chem Engn, Hangzhou 310014, Peoples R China; [Wang, Shengpeng; Chen, Bajin] Transfar Zhilian Co Ltd, Xiaoshan Econ & Technol Dev Zone, Hangzhou 311215, Peoples R China in 2020.0, Cited 84.0. COA of Formula: C13H8O2. The Name is 6H-Benzo[c]chromen-6-one. Through research, I have a further understanding and discovery of 2005-10-9

A visible-light photocatalytic aerobic oxidative lactonization of arene C(sp (2) )-H bonds proceeds in the presence of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) and tert -butyl nitrite (TBN). Under the optimized conditions, a range of 2-arylbenzoic acids is converted into the corresponding benzocoumarin derivatives in moderate to excellent yields. This method is characterized by its atom economy, mild reaction conditions, the use of a green oxidant and metal-free catalysis.

Welcome to talk about 2005-10-9, If you have any questions, you can contact Wang, YQ; Wang, SP; Chen, BJ; Li, MC; Hu, XQ; Hu, BX; Jin, LQ; Sun, N; Shen, ZL or send Email.. COA of Formula: C13H8O2

Reference:
Article; Zhang, Jian; Shi, Dongdong; Zhang, Haifeng; Xu, Zheng; Bao, Hanyang; Jin, Hongwei; Liu, Yunkui; Tetrahedron; vol. 73; 2; (2017); p. 154 – 163;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article Metal-Free Synthesis of Polysubstituted Imidazolinone Through Cyclization of Amidines with 2-Substituted Acrylates WOS:000514205500001 published article about OXIDATIVE COUPLING REACTION; FACILE SYNTHESIS; C-H; COPPER; AMINOOXYGENATION; DIAMINATION; ANALOGS; KETONES; ACTIVATION; ANNULATION in [Liu, Zhen; Shi, Min] East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Meilong Rd 130, Shanghai 200237, Peoples R China; [Liu, Zhen; Shi, Min] East China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, Meilong Rd 130, Shanghai 200237, Peoples R China; [Zhang, Yan-Shun; Wei, Yin; Shi, Min] Univ Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Chinese Acad Sci,Ctr Excellence Mol Synth, 345 Lingling Rd, Shanghai 200032, Peoples R China in 2020.0, Cited 41.0. The Name is Methyl 3-phenylpropionate. Through research, I have a further understanding and discovery of 103-25-3. HPLC of Formula: C10H12O2

Polysubstituted imidazolinones were synthesized in a facile metal-free cascade nucleophilic cyclization of easily available amidines and 2-substituted acrylates. This protocol is distinguished by simple, mild, and catalyst-free reaction conditions with a broad substrate scope, affording the desired products in moderate to good yields and providing an efficient strategy for synthesis of polysubstituted imidazolinone.

HPLC of Formula: C10H12O2. Welcome to talk about 103-25-3, If you have any questions, you can contact Liu, Z; Zhang, YS; Wei, Y; Shi, M or send Email.

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Category: esters-buliding-blocks. Recently I am researching about KNEE OSTEOARTHRITIS; NITRIC-OXIDE; MATRIX METALLOPROTEINASES; ARTICULAR CHONDROCYTES; RHEUMATOID-ARTHRITIS; SUPEROXIDE-DISMUTASE; HYDROGEN-PEROXIDE; SYNOVIAL-FLUID; EXPRESSION; MANAGEMENT, Saw an article supported by the University of Florence; Italian Ministry of Instruction, University and Research (MIUR)Ministry of Education, Universities and Research (MIUR). Published in MDPI in BASEL ,Authors: Micheli, L; Mannelli, LD; Mattoli, L; Tamimi, S; Flamini, E; Garetto, S; Lucci, J; Giovagnoni, E; Cinci, L; D’Ambrosio, M; Luceri, C; Ghelardini, C. The CAS is 103-26-4. Through research, I have a further understanding and discovery of Methyl 3-phenyl-2-propenoate

Current pharmacological therapies for the management of chronic articular diseases are far from being satisfactory, so new strategies need to be investigated. We tested the intra-articular pain relieving properties of a system of molecules from a characterizedCentella asiaticaextract (14G1862) in a rat model of osteoarthritis induced by monoiodoacetate (MIA). 14G1862 (0.2-2 mg mL(-1)) was intra-articularly (i.a.) injected 7 days after MIA, behavioural and histological evaluations were performed 14, 30 and 60 days after treatments. Moreover, the effect of 14G1862 on nitrate production and iNOS expression in RAW 264.7 macrophages stimulated with LPS was assessed. In vitro, 14G1862 treatment attenuated LPS-induced NO production and iNOS expression in a comparable manner to celecoxib. In vivo, 14G1862 significantly reduced mechanical allodynia and hyperalgesia, spontaneous pain and motor alterations starting on day 14 up to day 60. The efficacy was higher or comparable to that evoked by triamcinolone acetonide (100 mu g i.a.) used as reference drug. Histological evaluation highlighted the improvement of several morphological parameters in MIA + 14G1862-treated animals with particularly benefic effects on joint space and fibrin deposition. In conclusion, i.a. treatment withCentella asiaticais a candidate to be a novel effective approach for osteoarthritis therapy.

Category: esters-buliding-blocks. Welcome to talk about 103-26-4, If you have any questions, you can contact Micheli, L; Mannelli, LD; Mattoli, L; Tamimi, S; Flamini, E; Garetto, S; Lucci, J; Giovagnoni, E; Cinci, L; D’Ambrosio, M; Luceri, C; Ghelardini, C or send Email.

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

An article Synergistic adsorption of Cu(II) and photocatalytic degradation of phenanthrene by a jaboticaba-like TiO2/titanate nanotube composite: An experimental and theoretical study WOS:000450105700109 published article about HEAVY-METAL IONS; DEPOSITED TITANATE NANOTUBES; ZERO-VALENT IRON; WASTE-WATER; TITANIUM-DIOXIDE; SIMULTANEOUS REMOVAL; AQUEOUS-SOLUTIONS; TIO2; OXIDATION; MONTMORILLONITE in [Cheng, Kaiyu] Zhejiang Univ, Ocean Coll, Zhoushan 316021, Peoples R China; [Cai, Zhengqing; Sun, Xianbo] East China Univ Sci & Technol, Natl Engn Lab High Concentrat Refractory Organ Wa, Shanghai 200237, Peoples R China; [Cai, Zhengqing; Fu, Jie] Fudan Univ, Dept Environm Sci & Engn, Shanghai 200433, Peoples R China; [Sun, Weiliang] Tianjin Univ, Sch Chem Engn & Technol, Tianjin 300072, Peoples R China; [Chen, Long; Zhang, Dandan; Liu, Wen] Peking Univ, Key Lab Water & Sediment Sci, Minist Educ, Coll Environm Sci & Engn, Beijing 100871, Peoples R China in 2019.0, Cited 66.0. The Name is 6H-Benzo[c]chromen-6-one. Through research, I have a further understanding and discovery of 2005-10-9. Category: esters-buliding-blocks

Combined water pollution with the coexistence of heavy metals and organic contaminants is of great concern for practical wastewater treatment. In this study, a jaboticaba-like nanocomposite, titanate nanotubes supported TiO2 (TiO2/TiNTs), was synthesized by a two-step hydrothermal treatment. TiO2 /TiNTs had large surface area, abundant of -ONa/H groups and fine crystal anatase phase, thus exhibited both good adsorptive performance for Cu(II) and high photocatalytic activity for phenanthrene degradation. The maximum Cu(II) adsorption capacity on TiO2/TiNTs was 115.0 mg/g at pH 5 according to Langmuir isotherm model, and > 95% of phenanthrene was degraded within 4 h under UV light. TiO2/TiNTs showed about 10 times higher observed rate constant (k(obs) ) for phenanthrene degradation compared to the unmodified TiNTs. More importantly, the coexistence of Cu(II) promoted photocatalytic degradation of phenanthrene, because the incorporated Cu(II) in the lattice of TiNTs could trap photo-excited electron and thus inhibited the electron-hole recombination. Density functional theory (DFT) calculation indicated that the sites of phenanthrene with high Fukui index (f(0)) preferred to be attacked by center dot OH radicals. The quantitative structure-activity relationship (QSAR) analysis revealed that the degradation intermediates had lower acute toxicity and mutagenicity than phenanthrene. TiO2/TiNTs also owned high stability, as only slight loss of Cu(II) and phenanthrene removal efficiency was observed even after four reuse cycles. The developed material in this study is of great application potential for water or wastewater treatment with multi-contaminants, and this work can help us to better understand the mechanisms on reaction between Ti-based nanomaterials and different kinds of contaminants.

About 6H-Benzo[c]chromen-6-one, If you have any questions, you can contact Cheng, KY; Cai, ZQ; Fu, J; Sun, XB; Sun, WL; Chen, L; Zhang, DD; Liu, W or concate me.. Category: esters-buliding-blocks

Reference:
Article; Zhang, Jian; Shi, Dongdong; Zhang, Haifeng; Xu, Zheng; Bao, Hanyang; Jin, Hongwei; Liu, Yunkui; Tetrahedron; vol. 73; 2; (2017); p. 154 – 163;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recently I am researching about C BOND-CLEAVAGE; PHOTOREDOX CATALYSTS; CARBOXYLIC-ACIDS; DIBENZOPYRANONES; RADICALS; FUNCTIONALIZATION; C(SP(2))-H; COMPLEXES; LACTONES, Saw an article supported by the SERB, New Delhi [SB/S2/RJN-138/2018]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Wadekar, K; Aswale, S; Yatham, VR. The CAS is 2005-10-9. Through research, I have a further understanding and discovery of 6H-Benzo[c]chromen-6-one. COA of Formula: C13H8O2

The first cerium photocatalyzed dehydrogenative lactonization of 2-arylbenzoic acids has been developed. This operationally simple protocol allows rapid access to synthetically useful coumarins on gram scale by employing CeCl3 as a photocatalyst and O-2 as a terminal oxidant. Overall, this delivers an economical and environmentally amiable entry to diversely substituted coumarins, important structural motifs in bioactive molecules.

COA of Formula: C13H8O2. Welcome to talk about 2005-10-9, If you have any questions, you can contact Wadekar, K; Aswale, S; Yatham, VR or send Email.

Reference:
Article; Zhang, Jian; Shi, Dongdong; Zhang, Haifeng; Xu, Zheng; Bao, Hanyang; Jin, Hongwei; Liu, Yunkui; Tetrahedron; vol. 73; 2; (2017); p. 154 – 163;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Authors Huang, L; Gu, YT; Furstner, A in WILEY-V C H VERLAG GMBH published article about C-H ACTIVATION; GRIGNARD-REAGENTS; ELECTROCYCLIC REACTIONS; CONJUGATE ADDITION; SCALABLE SYNTHESIS; ATE COMPLEXES; REACTIVITY; ALKYL; SCOPE; CYCLOISOMERIZATION in [Huang, Lin; Gu, Yiting; Fuerstner, Alois] Max Planck Inst Kohlenforsch, D-45470 Mulheim, Germany in 2019.0, Cited 109.0. Recommanded Product: Methyl 3-phenylpropionate. The Name is Methyl 3-phenylpropionate. Through research, I have a further understanding and discovery of 103-25-3

In the presence of simple iron salts, 2-pyridone derivatives react with Grignard reagents under mild conditions to give the corresponding 1,6-addition products; if the reaction medium is supplemented with an aprotic dipolar cosolvent after the actual addition step, the intermediates primarily formed succumb to ring opening, giving rise to non-thermodynamic Z,E-configured dienoic acid amide derivatives which are difficult to make otherwise. Control experiments as well as the isolation and crystallographic characterization of a (tricarbonyl)iron pyridone complex suggest that the active iron catalyst generated in situ exhibits high affinity to the polarized diene system embedded into the heterocyclic ring system of the substrates, which likely serves as the actual recognition element.

Recommanded Product: Methyl 3-phenylpropionate. Bye, fridends, I hope you can learn more about C10H12O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recommanded Product: Methyl 3-phenyl-2-propenoate. In 2020.0 FRONT PHARMACOL published article about MINERALOCORTICOID RECEPTOR; MOUTAN CORTEX; ACID; MECHANISMS; FIBROSIS; EXTRACT; MODEL; RUTIN in [Song, Xiaotong; Zhao, Yue; Wang, Shijun; Wang, Yuan; Chen, Qian; Zhao, Haijun; Tian, Sheng; Yu, Huayun; Wu, Zhichun] Shandong Univ Tradit Chinese Med, Coll Tradit Chinese Med, Jinan, Peoples R China; [Song, Xiaotong; Wang, Shijun; Wang, Yuan; Chen, Qian; Zhao, Haijun; Tian, Sheng; Yu, Huayun; Wu, Zhichun] Shandong Coinnovat Ctr Class TCM Formula, Shandong Prov Educ Dept, Jinan, Peoples R China; [Wang, Hua] Shandong Univ Tradit Chinese Med, Dept Geriatr Med, Jinan, Peoples R China in 2020.0, Cited 50.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4.

Left ventricular hypertrophy (LVH) is an important characteristic of hypertensive heart disease. Renin-angiotensin system (RAS) blockers have been shown to be effective drugs for the reversal of LVH. Clinical and experimental studies have shown that Zi Shen Huo Luo Formula (ZSHLF) can improve the efficacy of perindopril in the treatment of hypertensive LVH, but its mechanism is unclear. This study aimed to investigate the possible mechanism to improve the efficacy of perindopril. First, we identified 23 compounds in ZSHLF by ultra performance liquid chromatography/tandem mass spectrometry (UPLC-MS/MS) analysis, among which ferulic acid, caffeic acid, vanillic acid, berberine, rutin, quercetin, kaempferol, stachydrine, and tiliroside have been reported to reduce blood pressure and exhibit cardioprotective effects. Second, we treated spontaneously hypertensive rats (SHRs) with perindopril and ZSHLF for 12 continuous weeks and found that chronic use of perindopril could increase the aldosterone (ALD) levels and cause aldosterone breakthrough (ABT). ZSHLF combined with perindopril reduced the ALD levels, interfered with ABT, decreased blood pressure, improved left ventricular diastolic dysfunction, and decreased the collagen volume fraction; these effects were superior to those of perindopril alone. In vitro experiments, ALD-induced cardiomyocytes (H9c2 cells) and cardiac fibroblasts were treated with ZSHLF-containing serum, which suppressed ALD-induced cardiomyocyte hypertrophy and cardiac fibroblast proliferation, increased mineralocorticoid receptor (MR) and Cav-1 colocalization and decreased phosphorylated epidermal growth factor receptor (pEGFR) and phosphorylated extracellular signal-regulated kinase (pERK) protein expression the cells. In conclusion, ZSHLF can interfere with ABT and affect the pathological role of ALD by affecting MR and Cav-1 interactions and EGFR/ERK signaling pathway. These effects represent a possible mechanism by which ZSHLF improves the efficacy of angiotensin-converting enzyme inhibitors (ACEIs) in hypertensive LVH treatment. However, the major bioactive components or metabolites responsible for the effects and the implications of these findings in patients need further verification.

Recommanded Product: Methyl 3-phenyl-2-propenoate. Bye, fridends, I hope you can learn more about C10H10O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

I found the field of Biochemistry & Molecular Biology; Chemistry very interesting. Saw the article A Novel Discovery: Holistic Efficacy at the Special Organ Level of Pungent Flavored Compounds from Pungent Traditional Chinese Medicine published in 2019.0. Category: esters-buliding-blocks, Reprint Addresses Zhang, YL; Qiao, YJ (corresponding author), Beijing Univ Chinese Med, Sch Chinese Mat Med, Beijing 102488, Peoples R China.; Zhang, YL; Qiao, YJ (corresponding author), State Adm Tradit Chinese Med, Res Ctr TCM Informat Engn, Beijing 102488, Peoples R China.. The CAS is 103-26-4. Through research, I have a further understanding and discovery of Methyl 3-phenyl-2-propenoate

Pungent traditional Chinese medicines (TCMs) play a vital role in the clinical treatment of hepatobiliary disease, gastrointestinal diseases, cardiovascular diseases, diabetes, skin diseases and so on. Pungent TCMs have a vastness of pungent flavored (with pungent taste or smell) compounds. To elucidate the molecular mechanism of pungent flavored compounds in treating cardiovascular diseases (CVDs) and liver diseases, five pungent TCMs with the action of blood-activating and stasis-resolving (BASR) were selected. Here, an integrated systems pharmacology approach is presented for illustrating the molecular correlations between pungent flavored compounds and their holistic efficacy at the special organ level. First, we identified target proteins that are associated with pungent flavored compounds and found that these targets were functionally related to CVDs and liver diseases. Then, based on the phenotype that directly links human genes to the body parts they affect, we clustered target modules associated with pungent flavored compounds into liver and heart organs. We applied systems-based analysis to introduce a pungent flavored compound-target-pathway-organ network that clarifies mechanisms of pungent substances treating cardiovascular diseases and liver diseases by acting on the heart/liver organ. The systems pharmacology also suggests a novel systematic strategy for rational drug development from pungent TCMs in treating cardiovascular disease and associated liver diseases.

Category: esters-buliding-blocks. Bye, fridends, I hope you can learn more about C10H10O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In 2019.0 APPL ORGANOMET CHEM published article about EFFICIENT CATALYST; MESOPOROUS SILICA; PARTICLES; PD in [Sarvi, Iraj; Gholizadeh, Mostafa; Izadyar, Mohammad] Ferdowsi Univ Mashhad, Dept Chem, Fac Sci, Mashhad 917751436, Iran in 2019.0, Cited 30.0. The Name is Methyl 3-phenyl-2-propenoate. Through research, I have a further understanding and discovery of 103-26-4. Safety of Methyl 3-phenyl-2-propenoate

We report the synthesis of magnetically separable Fe3O4@Silica-Threonine-Pd-0 magnetic nanoparticles with a core-shell structure. After synthesis of Fe3O4@Silica, threonine as an efficient stabilizer/ligand was bonded to the surface of Fe3O4@Silica. Then, palladium nanoparticles were generated on the threonine-modified catalyst. The threonine stabilizer helps to generate palladium nanoparticles of small size (less than 4 nm) with high dispersity and uniformity. Magnetically separable Fe3O4@Silica-Threonine-Pd-0 nanocatalyst was fully characterized using various techniques. This nanocatalyst efficiently catalysed the Heck cross-coupling reaction of a variety of substrates in water medium as a green, safe and inexpensive solvent at 80 degrees C. The Fe3O4@Silica-Threonine-Pd-0 catalyst was used for at least eight successful consecutive runs with palladium leaching of only 0.05%.

Safety of Methyl 3-phenyl-2-propenoate. Bye, fridends, I hope you can learn more about C10H10O2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Weng, Shiue-Shien; Ke, Chih-Shueh; Chen, Fong-Kuang; Lyu, You-Fu; Lin, Guan-Ying; Tetrahedron; vol. 67; 9; (2011); p. 1640 – 1648;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Recommanded Product: Methyl 3-phenylpropionate. I found the field of Chemistry very interesting. Saw the article Celite-Polyaniline supported palladium catalyst for chemoselective hydrogenation reactions published in 2019.0, Reprint Addresses Patel, AL; Bedekar, AV (corresponding author), Maharaja Sayajirao Univ Baroda, Fac Sci, Dept Chem, Vadodara 390002, India.. The CAS is 103-25-3. Through research, I have a further understanding and discovery of Methyl 3-phenylpropionate.

Polyaniline coated on particles of celite is used as support to load palladium catalyst. This heterogenized Celite center dot PANI center dot Pd system, is used as an efficient catalyst for chemoselective hydrogenation reactions. The catalyst is characterized by usual spectral, analytical techniques and studied for hydrogenation reactions at ambient conditions. The mild reaction conditions allow the control over the reactions and excellent selectivity is achieved in number of conversions. Hydrogenation of a carbon-carbon double bond was favored over other polar pi-bond systems, while labile functional groups such as benzyl ether, benzyl esters, cyano, nitro and halogen remained unaffected. Primary amines were converted to N,N-dimethyl amines with formaldehyde, the double bond of coumarin was selectively hydrogenated without opening of the lactone functionality.

Welcome to talk about 103-25-3, If you have any questions, you can contact Patel, HA; Rawat, M; Patel, AL; Bedekar, AV or send Email.. Recommanded Product: Methyl 3-phenylpropionate

Reference:
Patent; SANOFI; US2011/294788; (2011); A1;,
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics