Tag: M.W=150-200

Zhang, Ji-Shu published the artcilePalladium-Catalyzed Direct Decarbonylative Phosphorylation of Benzoic Acids with P(O)-H Compounds, Category: esters-buliding-blocks, the publication is European Journal of Organic Chemistry (2020), 2020(9), 1148-1153, database is CAplus.

A direct decarbonylative phosphorylation of benzoic acids catalyzed by palladium was disclosed. Under the reaction conditions, a wide range of benzoic acids coupled readily with all the three kinds of P(O)-H compounds, i.e. secondary phosphine oxides, H-phosphinates and H-phosphonates, producing the corresponding organophosphorus compounds in good to high yields. This reaction could be conducted at a gram scale and applied in the late-stage phosphorylative modification of carboxylic acids drug mols. These results well demonstrated the potential synthetic value of this new reaction in organic synthesis.

European Journal of Organic Chemistry published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C9H21NO3, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Cheng, Huan published the artcileComparison and evaluation of aroma-active compounds for different squeezed Chinese bayberry (Myrica rubra) juices, Recommanded Product: Methyl 3-phenyl-2-propenoate, the publication is Journal of Food Processing and Preservation (2021), 45(11), e15924, database is CAplus.

Chinese bayberry is one of the most valuable fruits with unique flavor in China. Juice aroma can be affected by processing methods, especially squeezing. The present study aimed to differentiate the aroma profiles of bayberry juices under 4 squeezing conditions (freshly/frozenly squeezed at room temperature/4°C). A total of 66 volatiles and 25 active aroma were identified as “green,” “floral,” “fruity” and “woody” odor. The contents of volatiles, including aldehydes, alcs., and esters in the freshly squeezed groups were significantly higher than frozenly squeezed groups. It was found juices squeezed at room temperature had “fermented” flavor. The total content of volatiles in frozenly squeezed at room temperature was the lowest, especially β-caryophyllene and humulene. By using GC-MS-O combined with principal component anal., the bayberry juice freshly squeezed at 4°C was of the best flavor quality, which would be used as optimal condition for squeezing process of bayberry fruits. Novelty impact statement : This work further investigates the effect of 4 different squeezing conditions on volatile aroma compounds of bayberry juice. According to the results of GC-MS-O combined with principal component anal., the contents of volatiles, including aldehydes, alcs., and esters in the freshly squeezed groups, were significantly higher than frozenly squeezed groups, and the bayberry juice obtained by squeezing fresh fruit at 4°C had the best aroma quality.

Journal of Food Processing and Preservation published new progress about 103-26-4. 103-26-4 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester,Protease,Tyrosinase,Natural product, name is Methyl 3-phenyl-2-propenoate, and the molecular formula is C10H10O2, Recommanded Product: Methyl 3-phenyl-2-propenoate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Zhang, Xu published the artcileBiodegradable Copolyesters with Unexpected Highly Blocky Microstructures and Enhanced Thermal Properties, Synthetic Route of 627-93-0, the publication is ACS Sustainable Chemistry & Engineering (2022), 10(14), 4438-4450, database is CAplus.

To synthesize novel biodegradable polyesters with high heat resistance and good crystallization capability, we designed a series of aliphatic-aromatic copolyesters, i.e., poly(isoidide-2,5-dimethylene adipate-co-terephthalate)s (PIATs) based on isoidide-2,5-dimethanol (IIDML), a rigid carbohydrate-based building block. The M_n values and intrinsic viscosities of PIAT copolyesters containing up to 40 mol % aromatic moieties are in the range of 6 000-19 000 g·mol^-1 and 0.5-0.87 dL·g^-1, resp. Interestingly, the products were obtained as blocky copolymers after the one-pot melt polycondensation process because of the thermodn. equilibrium of IIDML moieties driven by the insufficient thermal stability of the IIDML moieties. In addition, all the copolyesters are semicrystalline with crystallinity from 28% to 55% and tunable T_m values ranging from 88°C to a remarkable 189°C. They exhibit better (bio)degradability than the same type of polyesters. This work shows that this green monomer plays a key role in balancing thermal properties (especially T_g) and (bio)degradability, and these polyesters potentially broaden the application toward, for example, fibers.

ACS Sustainable Chemistry & Engineering published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C6H13I, Synthetic Route of 627-93-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Xu, Yuanyuan published the artcileRadical Photopolymerization Using 1,4-Dihydropyrrolo[3,2-b]pyrrole Derivatives Prepared via One-Pot Synthesis, Quality Control of 10287-53-3, the publication is ACS Omega (2021), 6(32), 20902-20911, database is CAplus and MEDLINE.

Radical photopolymerization has attracted significant attention for manufacturing products with complicated structures. Herein, the synthesized 1,4-bis(4-bromophenyl)-2,5-bis(4-nitrophenyl)-1,4-dihydropyrrole[3,2-b]pyrrole (PyBN, I, CAS Number 2561424-73-3) is found to show varying photoactivity upon irradiation at different wavelengths. PyBN affords two main absorption bands, and its maximum absorption peak is at 462 nm, attributing to its strong intramol. charge transfer property based on the donor-acceptor structure. It efficiently photoinitiates the radical photopolymerization of different (meth)acrylate materials under 365 and 395 nm LED irradiation The highest double bond conversion of 99.86% is achieved for these materials. Under 470 nm LED, PyBN does not show mol. structure change from photolysis results as a result of intramol. charge transfer. Therefore, PyBN shows wavelength-selective photoactivity with potential application in dual-wavelength volumetric additive manufacturing A unique solid product is successfully fabricated using a 365 nm LED with co-irradiation of a 470 nm LED. Addnl., PyBN incorporating camphorquinone (CQ) as a two-component visible light photoinitiator system is investigated under 470 nm LED irradiation As PyBN has a charge transfer activity at 470 nm, the combination with CQ exhibits a good synergistic interaction. Besides nitro-based PyBN, a methyl-based PyBC was prepared as a reference compound

ACS Omega published new progress about 10287-53-3. 10287-53-3 belongs to esters-buliding-blocks, auxiliary class Amine,Benzene,Ester, name is Ethyl 4-dimethylaminobenzoate, and the molecular formula is C20H17FO4S, Quality Control of 10287-53-3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Du, Yiming published the artcileTransition-Metal-Free, Intermolecular Azidoheteroarylation of Alkenes: Efficient Access to β-Azidoalkylated Quinoxalinones and Preliminary Antifungal Evaluation Against Magnaporthe grisea, Product Details of C12H14O2, the publication is Synthesis (2020), 52(16), 2395-2409, database is CAplus.

An efficient, PhI(OAc)₂-mediated, radical azidoheteroarylation of alkenes under transition-metal-free conditions is reported by employing TMSN₃ and quinoxalin-2(1 H)-ones as coupling partners. This domino reaction allows an efficient synthesis of valuable orangoazides containing quinoxalin-2(1 H)-one derivatives and could be extended to phosphinyl-alkylated quinoxalin-2(1 H)-one in a single step in moderate to excellent yields under mild conditions, as demonstrated by the preliminary antifungal evaluation against Magnaporthe grisea for the first time. Mechanistic studies revealed that this transformation undergoes a cascade addition pathway controlled by a polar radical. Thus, e.g., 1-methylquinoxalin-2(1H)-one + 1-hexene + TMSN₃ â†?I (96%) in MeCN in presence of Li₂CO₃ as base and PhI(OAc)₂ as oxidant.

Synthesis published new progress about 5205-11-8. 5205-11-8 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Benzene,Ester, name is 3-Methylbut-2-en-1-yl benzoate, and the molecular formula is C12H14O2, Product Details of C12H14O2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ranganathan, Palraj published the artcileOptically transparent bio-based polyamides with microcellular foaming properties derived from renewable difunctional aminoamides, Application In Synthesis of 627-93-0, the publication is Journal of Applied Polymer Science (2022), 139(2), 51461, database is CAplus.

A green approach for the synthesis of bio-based polyamides (PAs) with a new macromol. structure was developed. These bio-based PAs were synthesized by solvent and catalyst-free polycondensation combining fatty dimer acid Pripol 1009 with new difunctional aminoamides (DAAs). The later DAAs building blocks were synthesized by aminolysis of renewable di-Me sebacate (DMS) and di-Me adipate (DMA) with 3 different aliphatic diamines having diverse chain lengths, 2, 4, and 6 carbons. Bio-based PAs showed M_w up to 30,581 g/mol, initial thermal degradation over 380°, T_m from 168.3-202.4°C, T_g from 28.3-37.5°C, strain from 36.4 ±4.0-313.5 ±2.0%, and tensile strength up to 27.4 ±0.1 MPa. All the PAs films had excellent optical transparency with cut-off wavelengths of 276.0-283.0 nm, transmittance from 82.7%-90.7% at 600 nm. As a proof-of-concept of their usage, 1 of the PA can form microcellular foam by the green scCO₂ method. The foams possessed uniform (cell size; 40μm, foam d.; 0.265 g/cm³, expansion rate; 7.2) and bimodal (cell size; 24/38μm, foam d.; 0.302 g/cm³, expansion rate; 6.5) cell textures depending on their foaming temperatures This is the first report of bio-based PA foams and transparent films manufacturing without toxic solvents.

Journal of Applied Polymer Science published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C8H14O4, Application In Synthesis of 627-93-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Tang, Shuqin published the artcileA Cocktail of Industrial Chemicals in Lipstick and Nail Polish: Profiles and Health Implications, Computed Properties of 627-93-0, the publication is Environmental Science & Technology Letters (2021), 8(9), 760-765, database is CAplus.

Beauty products contain various industrial chems. to increase their functionality and appearance. The frequent use of beauty products may increase human exposure to industrial chems., but to date, their chem. components remain poorly characterized. Our work characterized the chem. components in lipstick and nail polish by screening for a total of 231 chems. from seven categories, including organophosphate esters (OPEs), phthalate esters (PAEs), non-PAE plasticizers, bisphenol analogs, parabens, UV stabilizers, and antioxidants. Their total concentrations ranged from 38.9 to 3810 μg/g (median of 193 μg/g) and from 18.6 to 1910 μg/g (307 μg/g) in lipstick (n = 34) and nail polish (n = 15), resp. The chem. compositions differed between lipstick and nail polish, but non-PAE plasticizers generally dominated over other groups of chems. A number of emerging plasticizers, OPEs, and UV stabilizers have rarely been reported in personal care products or environmental samples but were found at very high levels in beauty products, raising concern about their environmental release and human exposure risk. Although the employment of a hazard quotient approach suggested low health risks for exposure to industrial chems. from the use of beauty products, potential mixture effects from the chem. cocktail and occupational exposure to beauty products should not be overlooked.

Environmental Science & Technology Letters published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C4Br2N2O4S, Computed Properties of 627-93-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Stenzel, Katharina published the artcileIsophthalic Acid-Based HDAC Inhibitors as Potent Inhibitors of HDAC8 from Schistosoma mansoni, Application In Synthesis of 1877-71-0, the publication is Archiv der Pharmazie (Weinheim, Germany) (2017), 350(8), n/a, database is CAplus and MEDLINE.

Schistosoma mansoni histone deacetylase 8 (SmHDAC8) has been recently identified as a new potential target for the treatment of schistosomiasis. A series of newly designed and synthesized alkoxyamide-based and hydrazide-based HDAC inhibitors were tested for inhibitory activity against SmHDAC8 and human HDACs 1, 6, and 8. The front runner compounds showed submicromolar activity against SmHDAC8 and modest preference for SmHDAC8 over its human orthologue hHDAC8. Docking studies provided insights into the putative binding mode in SmHDAC8 and allowed rationalization of the observed selectivity profile.

Archiv der Pharmazie (Weinheim, Germany) published new progress about 1877-71-0. 1877-71-0 belongs to esters-buliding-blocks, auxiliary class Carboxylic acid,Benzene,Ester, name is 3-(Methoxycarbonyl)benzoic acid, and the molecular formula is C11H8O3, Application In Synthesis of 1877-71-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Moritz, Jan-Ole published the artcileP-Chirogenic Diphosphazanes with Axially Chiral Substituents and Their Use in Rh-Catalyzed Asymmetric Hydrogenation, Synthetic Route of 617-52-7, the publication is Journal of Organic Chemistry (2020), 85(22), 14537-14544, database is CAplus and MEDLINE.

A convenient synthesis of enantiopure P-chirogenic diphosphazanes incorporating bulky bisphenol and 1,1′-bi-2-naphthol-derived substituents via the functionalization of a readily accessible enantiopure lithium phosphinoamide with chlorophosphoridites was developed. Since the product requires no subsequent deprotection, the protocol provides an easy, convenient synthesis of P-chirogenic ligands on the gram scale. The ligands were applied in the Rh-catalyzed asym. hydrogenation of benchmark substrates furnishing enantiomeric excess values up to 96%.

Journal of Organic Chemistry published new progress about 617-52-7. 617-52-7 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Aliphatic hydrocarbon chain,Ester, name is Dimethyl itaconate, and the molecular formula is C7H10O4, Synthetic Route of 617-52-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Chen, Yu-Hao published the artcileSynthesis and characterization of low-temperature polyamide 6 (PA6) copolyamides used as hot melt adhesives and derived from the comonomer of novel aliphatic diamine bis(2-aminoethyl) adipamide and adipic acid, Synthetic Route of 627-93-0, the publication is International Journal of Adhesion and Adhesives (2020), 102619, database is CAplus.

A novel aliphatic PA6 copolyamide (PA6(BAEA/AA))-based hot melt adhesive was synthesized from ε-caprolactam with the organic salt of bis(2-aminoethyl) adipamide (BAEA) and adipic acid (AA), with BAEA/AA content ranges from 5 to 15 mol%. The chem. structures of BAEA diamine, BAEA/AA organic salt, PA6(BAEA/AA) copolyamides, and neat PA6 were obtained using FT-IR and ¹H NMR. Determined by the comonomer compositions, the relative viscosity and mol. weight (Mw) of the PA6(BAEA/AA) were from 2.29 to 2.74 and from 14,530 to 19,500 g mol^-1, resp. Adding the BAEA/AA structure strongly affected the crystallization behavior and thermal properties of the copolyamides. DSC results revealed that the melting temperature (T_m) of the copolyamides declined as the mole% of BAEA/AA increased in the range 5-15 mol%, and a TGA test revealed that the thermal decomposition of the copolyamides was similar to that of neat PA6. The Tm, glass transition temperature (T_g), and thermal stability (Td5%) with a BAEA/AA salt content of 10 mol% had the lowest values of 162.2, 40.3, 354.6°C, resp., while the fusion enthalpy (ΔHm) was lowest at 15 mol% (21.2 J g^-1). Most remarkably, PA6(BAEA/AA) exhibits much better mech. properties such as tensile strength (33.6-52.6 MPa) and elongation at breakage (114.7-584.5%), than the PA6 homopolymer. The peel strength of PA6 reached a maximum value of 53.4 N cm^-1 at 10 mol% of BAEA/AA salt, and this value is better than those of com. hot melt adhesives.

International Journal of Adhesion and Adhesives published new progress about 627-93-0. 627-93-0 belongs to esters-buliding-blocks, auxiliary class Ploymers, name is Dimethyl adipate, and the molecular formula is C8H14O4, Synthetic Route of 627-93-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics