Tag: M.W=100-150

Yang, Wenge published the artcileEffect of electron beam irradiation on volatile flavors in Tegillarca granosa meat, Category: esters-buliding-blocks, the publication is Zhongguo Shipin Xuebao (2012), 12(3), 176-184, database is CAplus.

The effect of electron beam irradiation on the volatile flavors in Tegillarca granosa meat was investigated. The volatile flavors in Tegillarca granosa meat were isolated by solid-phase microextraction and analyzed by gas chromatog./mass spectrometry after irradiation of different doses. After irradiation of 1 9kGy, the sorts of volatile flavors increased from 46 to 55, 57, 52, 58 and 66, resp. Volatile carbonyl compounds were the principal parts of volatiles, among which ketones made the contribution of sweet flower scent, while some aldehydes provided the lipid-like and fruity aromas. The unusual smell of 7 kGy group samples should be relevant to the abundant volatile carbonyl compounds The relative content of volatile alcs. increased after irradiation of 3, 5 kGy, containing some enols which might make the flavors softer. However, some kinds of olefins could to a certain extent remove the fishy smell. Electron beam irradiation brought about the increases of heterocyclic compounds Furan contributed to the fruity aromas in Tegillarca granosa meat. Besides, (S-and N-containing compounds including) pyridines and thiazoles provided the flavors of fried meat and nuts. Compared with the other exptl. groups, aromatic compounds exhibited the highest relative content with the dose of 5 kGy, among which benzaldehyde had the almond aroma, making the whole flavor of Tegillarca granosa meat better, to some degree. Electron beam irradiation with the doses of 3-5 kGy produced no significant impact on the original aromas of Tegillarca granosa meat. Furthermore, the irradiation might improve the whole flavors, to some extent.

Zhongguo Shipin Xuebao published new progress about 5340-78-3. 5340-78-3 belongs to esters-buliding-blocks, auxiliary class Aliphatic Chain, name is Ethyltert-butylacetate, and the molecular formula is C11H8F2, Category: esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Tan, Shaobo published the artcileBase Catalyzed Thiol-Ene Click Chemistry toward Inner -CH=CF- Bonds for Controlled Functionalization of Poly(vinylidene fluoride), HPLC of Formula: 19788-49-9, the publication is Macromolecular Chemistry and Physics (2018), 219(11), n/a, database is CAplus.

A facile and controlled base catalyzed thiol-ene click chem. toward electron-deficient -CH-CF- double bonds in poly(vinylidene fluoride) PVDF (P(VDF-DB)) is reported in present contribution for the first time. The addition reaction is carefully conducted under varied conditions including at the elevated temperature, in the different solvents, and with the altered catalysts and thiols. The addition reaction is well confirmed to follow the base catalyzed route and exhibits close dependence onto the reaction conditions. Besides the addition reaction, the other two side reactions catalyzed by alkylamines, including the further main chain degradation of P(VDF-DB) substrates together with the nucleophilic substitution of thiols to -CH=CF- units, can be completely avoided by choosing a catalyst with a proper pK_a value. With respect to the universality and well controlled feature of the reaction, the low cost and readily prepared P(VDF-DB) substrate and the mild reaction conditions, this strategy may offer a robust tool for attaching various functional groups into PVDF side chain.

Macromolecular Chemistry and Physics published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C8H11BO2, HPLC of Formula: 19788-49-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Thombal, Raju S. published the artcilePalladium-Catalyzed Direct Oxidative C-H Activation/Annulation for Regioselective Construction of N-Acylindoles, HPLC of Formula: 30414-53-0, the publication is Organic Letters (2020), 22(9), 3397-3401, database is CAplus and MEDLINE.

A Pd(II)-catalyzed C(sp³)-H/C(sp²)-H coupling/annulation of anilides and α-dicarbonyl compounds for the synthesis of diverse N-acyl indoles was described. The reaction was achieved by cascade C-H activation, coupling, and intramol. cyclization. This protocol provided a variety of indoles with high functional group tolerance and excellent regioselectivity. The utility of this protocol was demonstrated by transforming the synthesized compound into diversely functionalized analogs.

Organic Letters published new progress about 30414-53-0. 30414-53-0 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ketone,Ester, name is Methyl 3-oxovalerate, and the molecular formula is C13H16O2, HPLC of Formula: 30414-53-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Cohen, Marianne published the artcileBiomolecules from olive pruning waste in Sierra Magina – Engaging the energy transition by multi-actor and multidisciplinary analyses, Safety of 3-Acetyldihydrofuran-2(3H)-one, the publication is Journal of Environmental Management (2018), 204-213, database is CAplus and MEDLINE.

The price volatility of fossil resources, the uncertainty of their long-term availability and the environmental, climatic and societal problems posed by their operation lead to the need of an energy transition enabling the development and utilization of other alternative and sustainable resources. Acknowledging that indirect land-use change can increase greenhouse gas emission, the European Union (EU) has reshaped its biofuel policy. It has set criteria for sustainability to ensure that the use of biofuels guarantees real carbon savings and protects biodiversity. Approaching economic, environmental and social sustainability at the local level and in an integrated way should help to maximize benefits and minimize risks. This approach has been adopted and is described in the present work that combines chem., biol., social and territorial studies on the management of pruning waste residues from olive trees in the Sierra Magina in Spain. The biol. and social analyses helped to orientate the research towards an attractive chem. process based on extraction and pyrolysis, in which high added value mols. are recovered and in which the residual biochar may be used as pathogen-free fertilizer. In this region where farmers face declining economic margins, the new intended method may both solve greenhouse gas emission problems and provide farmers with addnl. revenues and convenient fertilizers.

Journal of Environmental Management published new progress about 517-23-7. 517-23-7 belongs to esters-buliding-blocks, auxiliary class Tetrahydrofuran,Ketone,Ester, name is 3-Acetyldihydrofuran-2(3H)-one, and the molecular formula is C6H8O3, Safety of 3-Acetyldihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Bendrath, Franziska published the artcileSynthesis and permethylation of methyl 5-(2-chloropyridin-3-yl)pentanoates, Product Details of C6H10O3, the publication is Chemistry of Heterocyclic Compounds (New York, NY, United States) (2021), 57(11), 1146-1148, database is CAplus.

Two Me 5-(2-chloropyridin-3-yl)pentanoates were prepared by condensation of 1,3-bis(silyloxy)-1,3-butadienes with 2-chloropyridine-3-carboxylic acid chloride. The permethylation of the products resulted in two completely different products, depending on the substitution pattern of the 1,3,5-tricarbonyl moiety.

Chemistry of Heterocyclic Compounds (New York, NY, United States) published new progress about 30414-53-0. 30414-53-0 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ketone,Ester, name is Methyl 3-oxovalerate, and the molecular formula is C6H10O3, Product Details of C6H10O3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Kamma, Emily published the artcileCentral nervous system macrophages in progressive multiple sclerosis: relationship to neurodegeneration and therapeutics, Product Details of C6H8O4, the publication is Journal of Neuroinflammation (2022), 19(1), 45, database is CAplus and MEDLINE.

A review. There are over 15 disease-modifying drugs that have been approved over the last 20 years for the treatment of relapsing-remitting multiple sclerosis (MS), but there are limited treatment options available for progressive MS. The development of new drugs for the treatment of progressive MS remains challenging as the pathophysiol. of progressive MS is poorly understood. The progressive phase of MS is dominated by neurodegeneration and a heightened innate immune response with trapped immune cells behind a closed blood-brain barrier in the central nervous system. Here we review microglia and border-associated macrophages, which include perivascular, meningeal, and choroid plexus macrophages, during the progressive phase of MS. These cells are vital and are largely the basis to define lesion types in MS. We will review the evidence that reactive microglia and macrophages upregulate pro-inflammatory genes and downregulate homeostatic genes, that may promote neurodegeneration in progressive MS. We will also review the factors that regulate microglia and macrophage function during progressive MS, as well as potential toxic functions of these cells. Disease-modifying drugs that solely target microglia and macrophage in progressive MS are lacking. The recent treatment successes for progressive MS include include B-cell depletion therapies and sphingosine-1-phosphate receptor modulators. We will describe several therapies being evaluated as a potential treatment option for progressive MS, such as immunomodulatory therapies that can target myeloid cells or as a potential neuroprotective agent.

Journal of Neuroinflammation published new progress about 624-49-7. 624-49-7 belongs to esters-buliding-blocks, auxiliary class Inhibitor,Natural product, name is Dimethyl fumarate, and the molecular formula is C6H8O4, Product Details of C6H8O4.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Besseau, Francois published the artcileHydrogen-bond basicity of esters, lactones and carbonates, Product Details of C7H13NO2, the publication is Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) (1994), 485-9, database is CAplus.

A thermodn. hydrogen-bond-basicity scale pK_HB (logarithm of the formation constant of 4-fluorophenol-base complexes in CCl₄) has been determined for esters, lactones and carbonates, and correlated to a spectroscopic basicity scale. In the esters R¹CO₂R² the hydrogen-bond basicity is decreased by bulky alkyl R¹ substituents (steric effect) but increased by branched and lengthened alkyl R² substituents (electronic effects). Quant. structure-basicity relationships have been established in the XCO₂Et (X varying from CF₃ to Me₂N) and XC₆H₄CO₂Et (X varying from 4-NO₂ to 4-Me₂N) series. Vinylol. strongly increases hydrogen-bond basicity: Me₂NCH:CHCO₂Et is the most basic ester presently known. Cyclization increases the hydrogen-bond basicity of esters and carbonates.

Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999) published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C7H13NO2, Product Details of C7H13NO2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Ziao, Nahosse published the artcileAmino nitrogen and carbonyl oxygen in competitive situations: which is the best hydrogen-bond acceptor site?, Product Details of C7H13NO2, the publication is CrystEngComm (2002), 326-335, database is CAplus.

The relative H-bond acceptor abilities of amino N and carbonyl O in various chem. environments were studied using data retrieved from the Cambridge Structural Database (CSD) and via ab initio MO calculations Surveys of the CSD for H bonds between HX (X = N, O) donors and push-pull or saturated amino ketone and amino ester mol. fragments show that the H bonds are much more frequent on the O than on the amino N. In the push-pull families, the H-bonding (HB) ability of the carbonyl O is increased by conjugation between the lone pair of the amino substituent and the C=O group, a behavior similar to resonance-assisted H bonding. The unexpected behavior of twisted amides, in which only the amino N is involved in H bonding, is pointed out. This unusual feature is explained by the disruption of conjugation between the amino lone pair and the carbonyl owing to the cyclization involving the amino moiety. In aliphatic systems, the amino N retains its HB ability but is still involved in a rather low number of contacts. This behavior reflects the sensitivity of the amino N to steric hindrance. The relative strengths of the H bonds on the carbonyl O in ketones and esters follow the exptl. order of H-bond basicity as observed in solution through the pK_HB scale. Ab initio MO calculations (B3LYP/6-31+G^** level) of electrostatic and charge transfer descriptors also confirm the exptl. observations. pK_a.

CrystEngComm published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C16H24BF4Ir, Product Details of C7H13NO2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Vu, Cuong M. published the artcileRecyclable CuFe₂O₄ for the synthesis of 2,3-disubstituted indoles, Related Products of esters-buliding-blocks, the publication is Tetrahedron Letters (2020), 61(50), 152629, database is CAplus.

A method for the CuFe₂O₄-catalyzed coupling of 2-iodo- or 2-bromoanilines 2-X-RC₆H₃NH₂ (R = H, 4-trifluoromethoxy, 5-trifluoromethyl, etc.; X = I or Br) and acetylacetone or isosteric 1,3-diketones R¹C(O)CH₂C(O)R² (R¹ = Me, ethyl; R² = ethoxy, methoxy) to afford 2,3-disubstituted indoles I (R³ = H, 5-bromo, 6-Me, etc.) has been developed. The superparamagnetic material showed superior activity in comparison to other ferrites or copper-based metal-organic frameworks. Functionalities including ester, cyano, and halogen groups were compatible with the reaction conditions. The CuFe₂O₄ catalyst was easily recoverable and reusable and offers a convenient pathway to afford synthetically useful heterocycles.

Tetrahedron Letters published new progress about 30414-53-0. 30414-53-0 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ketone,Ester, name is Methyl 3-oxovalerate, and the molecular formula is C9H10O3S, Related Products of esters-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Lan, Jin published the artcileSelective synthesis of functionalized quinazolinone derivatives via biocatalysis, SDS of cas: 30414-53-0, the publication is Molecular Catalysis (2020), 111261, database is CAplus.

A novel and efficient biocatalyzed methodol. for the construction of functionalized quinazolinone derivatives via tandem / hydrolysis / decarboxylation / cyclization and transesterification reactions has been developed that works with a variety of 2-aminobenzamide and β-dicarbonyl compounds This method requires mild conditions, and has demonstrated high catalytic activity, excellent yields, excellent chemoselectivity, and a broad substrate scope. Addnl., biocatalyzed decarboxylation does not require high temperatures or light activation, giving it a substantial advantage over alternative techniques. Most importantly, it offers a new example for the exploration of simple, convenient, and environmentally friendly synthetic routes utilizing enzymes in organic chem.

Molecular Catalysis published new progress about 30414-53-0. 30414-53-0 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ketone,Ester, name is Methyl 3-oxovalerate, and the molecular formula is C6H10O3, SDS of cas: 30414-53-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics