Tag: M.W=100-150

Gu, Jing published the artcileHyper-cross-linked polymer based carbonaceous materials as efficient catalysts for ethyl levulinate production from carbohydrates, Product Details of C7H12O3, the main research area is carbohydrate ethyl levulinate hypercrosslinked polymer carbonaceous material catalyst.

Catalytic upgrading of biomass into various alkyl levulinates has gained wide attention recently. Particularly, Et levulinate (EL) shows great potential as gasoline additive and substitute of biodiesel fuels. Hypercrosslinked organic polymer based carbonaceous materials with large surface areas and strong Bronsted acidity were synthesized and developed as highly efficient solid acids for the direct transformation of biomass derived carbohydrates into biofuel candidate Et levulinate (EL). Controllable Brunauer-Emmett-Teller (BET) surface area and proper acid d. of as-prepared carbonaceous materials were demonstrated to be crucial for the successful synthesis of EL. Among the catalysts, α,α’-dichloro-p-xylene derived hypercrosslinked organic carbocatalyst (HDS-3.6) exhibited the best results for EL formation with the optimal yield of 70.3% at a temperature of 423 K, which was comparable with those of frequently-used solid acids such as com. Amberlyst-15 and metal oxides. The presence of DMSO (DMSO) in the catalytic system facilitated the production of intermediates 5-hydroxymethylfurfural (HMF) and 5-ethoxymethylfurfural. Notably, the hypercrosslinked organic polymers with abundant Bronsted acid sites were much more effective in the catalytic synthesis of levulinate esters from ketoses. The prepared hypercrosslinked organic polymers were efficient and robust catalysts to produce various biomass derived alkyl levulinates with high activity and stability.

Journal of Chemical Technology and Biotechnology published new progress about Bronsted acidity. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Product Details of C7H12O3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ganji, Parameswaram published the artcileConversion of levulinic acid to ethyl levulinate using tin modified silicotungstic acid supported on Ta2O5, Computed Properties of 539-88-8, the main research area is levulinic acid esterification tin modified silicotungstic acid catalyst property.

Tin modified silicotungstic acid (STA) deposited on Ta2O5 was explored as suitable catalyst for the conversion of levulinic acid to Et levulinate. The microwave synthesized catalysts of varying amounts of STA were characterized by N2 adsorption, powder XRD, FT-IR, FE-SEM, XPS, pyridine-FT-IR, TGA-DTA and NH3-TPD. Among the synthesized catalysts, 50% Sn2STA/Ta2O5 catalyst exhibited excellent catalytic activity for the esterification of levulinic acid providing 78% of Et levulinate yield and stable recyclability up to three cycles. The rate of esterification was 6.6 × 10-3 mol/g/min, which is significantly higher compared to reported values in the open literature. Mechanistic investigations revealed that the high catalytic activity was influenced by the presence of appropriate Bronsted acid sites, surface area and porosity.

Catalysis Communications published new progress about Bronsted acidity. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Computed Properties of 539-88-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wan, Feifei published the artcileThe transfer hydrogenation of high concentration levulinic acid to γ-valerolactone catalyzed by glucose phosphate carbamide zirconium, Quality Control of 539-88-8, the main research area is glucose phosphate carbamide zirconium levulinic acid transfer hydrogenation catalyst; gamma valerolactone turnover frequency.

Zr-Based catalysts have been extensively applied in Meerwein-Ponndorf-Verley type catalytic transfer hydrogenation (CTH) reactions, but they are easily deactivated in the CTH conversion of high concentrations of levulinic acid (LA) to γ-valerolactone (γ-GVL). This work discloses that by using cheap glucose and ZrCl4 as two main raw materials, glucose phosphate carbamide zirconium (GluPC-Zr) is easily synthesized at large scale and low cost via a simple two-step conversion. The constructed GluPC-Zr has enhanced Lewis acid-base properties and good porosity, thus exhibiting outstanding activity for the CTH reactions of LA or its esters with isopropanol (IPA), providing 95-98% γ-GVL yields. Because of the excellent esterification performance of the introduced acidic phosphate groups, GluPC-Zr also works well at high LA concentrations, achieving a much higher turnover frequency (TOF, 8.2 mmol γ-GVL per g catalyst per h) than previously reported Zr-based catalysts (TOF, 0.2-2.4). And it shows excellent reusability in the reaction of LA with IPA, still providing ca. 95% γ-GVL yield after the seventh cycle run. This work provides a preferential esterification strategy for LA to hamper catalyst deactivation, which is of special significance for the large-scale production of γ-GVL from biomass-derived LA and a low-cost GluPC-Zr catalyst.

Green Chemistry published new progress about Bronsted acidity. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Quality Control of 539-88-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

He, Jian published the artcileDual acidic mesoporous KIT silicates enable one-pot production of γ-valerolactone from biomass derivatives via cascade reactions, Recommanded Product: Ethyl 4-oxopentanoate, the main research area is zirconium silica catalyst biomass derivative valerolactone one pot synthesis; morphol physicochem property.

γ-Valerolactone (GVL) is an interesting bio-based platform mol. that is utilized as green solvent and a versatile building block for the synthesis of bio-fuels and chems. Herein, an investigation on the efficient production of GVL from biomass-based carbonyl compounds such as furfural, levulinic acid, and its esters using 2-propanol as H-donor and solvent over stable Zr-incorporated mesoporous silica (KIT-5) catalysts was presented. Both Lewis and Bronsted acid sites were generated by the introduction of Zr into KIT-5, and the acid d. of the resulting Zr-KIT-5(Si/Zr) could be controlled by simply adjusting Si/Zr molar ratio. Among these bifunctional catalysts, Zr-KIT-5(10) showed superior catalytic performance in the production of GVL (>91% selectivity) from biomass-derived carboxides (ca. 94% conversion), which was demonstrated to pos. correlate with its large amount of acidic sites and facile access of active sites to interconnected pores. Moreover, the spent catalyst held about 90% of its original activity in the sixth run. Due to the presence of Bronsted and Lewis dual acidic sites in Zr-KIT-5, the direct conversion of furfural to GVL was also permitted in a single pot via tandem reactions involving hydrogenation, ring-opening, secondary hydrogenation, and subsequent cyclization.

Renewable Energy published new progress about Bronsted acidity. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Recommanded Product: Ethyl 4-oxopentanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Garcia, Margarita published the artcileSequential Non-Saccharomyces and Saccharomyces cerevisiae fermentations to reduce the alcoholcontent in wine, COA of Formula: C6H12O3, the main research area is Saccharomyces Wickerhamomyces Meyerozyma Metschnikowia fermentation alc reduction wine.

Over the last decades, the average alc. content of wine has increased due to climate change and consumer preferences for particular wine styles that resulted in increased grape sugar levels at harvest. Therefore, alc. reduction is a current challenge in the winemaking industry. Among several strategies under study, the use of non-conventional yeasts in combination with Saccharomyces cerevisiae plays an important role for lowering ethanol production in wines nowadays. In the present work, 33 native non-Saccharomyces strains were assayed in sequential culture with a S. cerevisiae wine strain to determine their potential for reducing the alc. content in Malvar white wines. Four of the non-Saccharomyces strains (Wickerhamomyces anomalus 21A-5C, Meyerozyma guilliermondii CLI 1217, and two Metschnikowia pulcherrima (CLI 68 and CLI 460)) studied in sequential combination with S. cerevisiae CLI 889 were best able to produce dry wines with decreased alc. proportion in comparison with one that was inoculated only with S. cerevisiae. These sequential fermentations produced wines with between 0.8% (volume/volume) and 1.3% (volume/volume) lower ethanol concentrations in Malvar wines, showing significant differences compared with the control. In addition, these combinations provided favorable oenol. characteristics to wines such as high glycerol proportion, volatile higher alcs., and esters with fruity and sweet character.

Fermentation published new progress about Candida stellata. 5405-41-4 belongs to class esters-buliding-blocks, name is Ethyl 3-hydroxybutanoate, and the molecular formula is C6H12O3, COA of Formula: C6H12O3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wanmolee, Wanwitoo published the artcileOne step liquefaction of hardwood lignin to oligomers soluble in polymerizable solvents, Application In Synthesis of 539-88-8, the main research area is liquefaction hardwood lignin oligomer soluble polymerizable solvent solubility.

Today tech. lignins produced from different industrial processes are underutilized because they possess recalcitrant C-C bonds and reduced proportion of ether bonds, making it difficult to produce building block compounds in high yields. Current methods being developed to process tech. lignin and improve its usefulness involve multiple steps and the use of toxic chems. We report an innovative cleave and couple one step catalytic process on eucalyptus lignin (EUL) to form unique aromatics oligomers with aliphatic side chains using KOH/HCOOH mixture with methanol as the solvent. Under optimum condition, 71 wt% of predominantly dimers and oligomers are formed which are readily soluble in polymerizable solvents such as Me methacrylate. In this one pot process, the KOH not only acts as the catalyst but ensures complete solubilization of EUL, allowing easier cleavage of bonds to form phenolic monomers and quinone groups (which undergo ring opening) followed by repolymn. to form oligomers. The study has opened pathways toward sustainable catalytic conversion of tech. lignin to reactive macromol. building blocks to produce soft nanomaterials.

Industrial Crops and Products published new progress about Depolymerization. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Application In Synthesis of 539-88-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Li, Peng published the artcileA fast and efficient way for recovering organic carbon resources from a coal byproduct: separation and structural evaluation, HPLC of Formula: 539-88-8, the main research area is coal byproduct organic carbon resources separation structural evaluation.

Solvent extraction is an efficient and nondestructive approach to produce ash-free organic matters from direct coal liquefaction residue (DCLR). Isometric acetone/CS2 mixture (IACM) was adopted to extract DCLR to produce IACM-soluble fraction (IACM-SF) with a yield of 86.5%. The IACM-SF is of ash-free and high carbon content of 90.18%. The typical structural features of IACM-SF are substituted aromatic structures, nonsubstituted condensed and biphenyl aromatic structures, alkyl bridged linkages, hydrogenated aromatic structures, and heteroatom-containing structures. Therefore, the IACM-SF is a useful and valuable carbon resource that can be used for producing aromatics and preparation of carbon materials.

Separation Science and Technology (Philadelphia, PA, United States) published new progress about Ashes (residues). 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, HPLC of Formula: 539-88-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Chen, Yuefang published the artcileSynergy of Al2(SO4)3 and H3PO4 in co-solvents converts starch to 5-ethoxymethylfurfural, Computed Properties of 539-88-8, the main research area is synergy Al2SO4 H3PO4 solvent starch ethoxymethylfurfural.

Efficient synthesis of promising biofuel 5-ethoxymethylfurfural (EMF) directly from starch was developed over a mixed-acid system composed of Al2(SO4)3 and H3PO4 in ethanol-DMSO co-solvent medium. The reaction proceeds through the depolymerization of starch to form glucose over Bronsted acidic H3PO4, which is then isomerized to fructose by Al2(SO4)3, a Lewis acid catalyst. The mixed-acid system then synergistically catalyzes the formation of EMF. At 170°C, 36.9%, 39.8%, and 34.7% yields of EMF can be captured from corn starch, amylose and amylopectin, resp. Moreover, the conversion of cellobiose and wood pulp cellulose produces 38.5% and 9.5% yields of EMF.

Catalysis Communications published new progress about Aprotic solvents. 539-88-8 belongs to class esters-buliding-blocks, name is Ethyl 4-oxopentanoate, and the molecular formula is C7H12O3, Computed Properties of 539-88-8.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Kim, Ho Shin published the artcileImprovement of Oral Bioavailability of Pyrazolo-Pyridone Inhibitors of the Interaction of DCN1/2 and UBE2M, HPLC of Formula: 623-50-7, the main research area is carcinoma DCN1 UBE2M interaction inhibitors NEDD8 pharmacokinetic oral bioavailability.

The cullin-RING ubiquitin ligases (CRLs) are ubiquitin E3 enzymes that play a key role in controlling proteasomal degradation and are activated by neddylation. We previously reported inhibitors that target CRL activation by disrupting the interaction of defective in cullin neddylation 1 (DCN1), a CRL neddylation co-E3, and UBE2M, a neddylation E2. Our first-generation inhibitors possessed poor oral bioavailability and fairly rapid clearance that hindered the study of acute inhibition of DCN-controlled CRL activity in vivo. Herein, we report studies to improve the pharmacokinetic performance of the pyrazolo-pyridone inhibitors. The current best inhibitor, 40 (I), inhibits the interaction of DCN1 and UBE2M, blocks NEDD8 transfer in biochem. assays, thermally stabilizes cellular DCN1, and inhibits anchorage-independent growth in a DCN1 amplified squamous cell carcinoma cell line. Addnl., we demonstrate that a single oral 50 mg/kg dose sustains plasma exposures above the biochem. IC90 for 24 h in mice.

Journal of Medicinal Chemistry published new progress about Antitumor agents. 623-50-7 belongs to class esters-buliding-blocks, name is Ethyl 2-hydroxyacetate, and the molecular formula is C4H8O3, HPLC of Formula: 623-50-7.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mowery, Patricia published the artcileDiscovery of an indole-substituted furanone with tubulin polymerization inhibition activity, Application of Ethyl 2-hydroxyacetate, the main research area is indole furanone drug discovery synthesis anticancer tubulin polymerization inhibition; Anticancer; Furanone; Indole; Tubulin.

Analogs of diarylpyrrolinone lead compound I were prepared and tested for anti-proliferative activity in U-937 cancer cells. Alterations of I focused on modifying the two nitrogen atoms: the pyrrolinone nitrogen atom was substituted with a Pr group or replaced with an oxygen atom (furanone); and the substituents on the indole nitrogen were varied. These changes led to the discovery of a furanone analog II with sub-micromolar anti-cancer potency and tubulin polymerization inhibition activity.

Bioorganic & Medicinal Chemistry Letters published new progress about Antitumor agents. 623-50-7 belongs to class esters-buliding-blocks, name is Ethyl 2-hydroxyacetate, and the molecular formula is C4H8O3, Application of Ethyl 2-hydroxyacetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics