Tag: M.W=100-150

Sourabie, Alain M. published the artcileIdentification of a Powerful Aroma Compound in Munster and Camembert Cheeses: Ethyl 3-Mercaptopropionate, Synthetic Route of 19788-49-9, the publication is Journal of Agricultural and Food Chemistry (2008), 56(12), 4674-4680, database is CAplus and MEDLINE.

With the view to investigate the presence of thiols in cheese, the use of different methods of preparation and extraction with an organomercuric compound (p-hydroxymercuribenzoate) enabled the isolation of a new compound The anal. of cheese extracts by gas chromatog. coupled with pulse flame photometry, mass spectrometry, and olfactometry detections led to the identification of Et 3-mercaptopropionate in Munster and Camembert cheeses. This compound, described at low concentrations as having pleasant, fruity, grapy, rhubarb, and empyreumatic characters, has previously been reported in wine and Concord grape but was never mentioned before in cheese. A possible route for the formation of this compound in relation with the catabolism of sulfur amino acids is proposed.

Journal of Agricultural and Food Chemistry published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C10H12O4S, Synthetic Route of 19788-49-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Van Es, Theodorus published the artcileN,1-Dialkyl-7-(alkylamino)-4-(alkylimino)-1,4-dihydroquinoline-3-carboxamides and their 4-oxo derivatives: synthesis and properties, Computed Properties of 924-99-2, the publication is South African Journal of Chemistry [online computer file] (2001), 1-16, database is CAplus.

Methods are described for accessing the little known class of 4-alkyliminoquinoline-3-carboxamide title compounds; viz., from 4-oxoquinoline-3-carboxylic acids treated successively with thionyl chloride and amine, from 4-oxoquinoline-3-carboxylic esters treated likewise, and from the hydrogen chloride salt of a 4-alkyliminoquinoline-3-carboxylic ester and amine. Mechanistic aspects of the syntheses are discussed, and some spectroscopic and chem. properties of the title compounds are presented.

South African Journal of Chemistry [online computer file] published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C13H9FO, Computed Properties of 924-99-2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Hayrapetyan, Davit published the artcileFacile Synthesis of Spirocyclic Lactams via [3+2] and [3+3] Aza-Annulation Reactions, COA of Formula: C6H8O3, the publication is European Journal of Organic Chemistry (2021), 2021(14), 2121-2125, database is CAplus.

Spirocyclic pyrrolidones and piperidones such as I and II were synthesized starting from readily available α-ketolactones and α-ketolactams employing [3+2]- and [3+3]-aza-annulation reactions. Tandem reactions of enamino lactams and lactones with maleic and itaconic anhydride yielded alkylidenespirolactams in good yields; further reduction of the exocyclic C=C double bond of the enamino moiety proceeded with excellent diastereoselectivity. Overall, one C-C and two C-N bonds, as well as three new stereocenters were created in a diastereoselective manner resulting in a fast upbuild of mol. complexity.

European Journal of Organic Chemistry published new progress about 517-23-7. 517-23-7 belongs to esters-buliding-blocks, auxiliary class Tetrahydrofuran,Ketone,Ester, name is 3-Acetyldihydrofuran-2(3H)-one, and the molecular formula is C6H8O3, COA of Formula: C6H8O3.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Nugent, Jeremy published the artcileSynthesis of α-quaternary bicyclo[1.1.1]pentanes through synergistic organophotoredox and hydrogen atom transfer catalysis, Recommanded Product: 3-Acetyldihydrofuran-2(3H)-one, the publication is Organic Letters (2021), 23(21), 8628-8633, database is CAplus and MEDLINE.

Bicyclo[1.1.1]pentanes (BCPs) are of importance in drug design as sp3-rich bioisosteres of arenes and tert-Bu groups, however the preparation of BCPs with adjacent quaternary carbons is barely known. Authors report a facile synthesis of α-quaternary BCPs using organophotoredox and hydrogen atom transfer catalysis in which α-keto radicals, generated through oxidation of β-ketocarbonyls, underwent efficient addition to [1.1.1]propellane. The BCP products can be transformed into a variety of useful derivatives including enantioenriched BCPs featuring α-quaternary stereocenters.

Organic Letters published new progress about 517-23-7. 517-23-7 belongs to esters-buliding-blocks, auxiliary class Tetrahydrofuran,Ketone,Ester, name is 3-Acetyldihydrofuran-2(3H)-one, and the molecular formula is C6H8O3, Recommanded Product: 3-Acetyldihydrofuran-2(3H)-one.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Tabarrini, Oriana published the artcileStructure Modifications of 6-Aminoquinolones with Potent Anti-HIV Activity, COA of Formula: C7H13NO2, the publication is Journal of Medicinal Chemistry (2004), 47(22), 5567-5578, database is CAplus and MEDLINE.

It was recently discovered that 6-aminoquinolone derivatives could be valid leads for the development of new anti-HIV agents because of their new and diversified mode of action. The studies carried out on the lead compound WM5 showed that this derivative is able to inhibit the Tat-mediated long terminal repeat driven transcription, an essential step in the HIV-1 replication cycle. Thus, starting from lead WM5, the design and synthesis of an enlarged series of 6-aminoquinolones, e.g. I (R¹ = Me, 2-benzothiazolyl, biphenyl, 4-FC₆H₄, etc.; R² = 2-MeOC₆H₄, 2-thiazolyl, 2-pyridyl, 5-methyl-1,3,4-thiadiazol-2-yl, etc.), was performed and their structure-activity relationship was studied. I (R¹ = Me; R² = 3-F₃CC₆H₄, 2-thiazolyl, 2-pyrazinyl, 2-benzoxazolyl) proved to be highly effective in inhibiting HIV replication at 50% inhibitory concentration in the range of 0.0087-0.7 μg/mL in MT-4, PBMCs and CEM cell lines coupled with pos. selectivity indexes that reach values higher than 1000 on CEM cell lines for I (R¹ = Me; R² = 2-thiazolyl, 2-pyrazinyl). Time-of-addition experiments clearly confirm that the new, potent 6-aminoquinolones interact at a postintegration step in the replication cycle of HIV.

Journal of Medicinal Chemistry published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C12H15NO, COA of Formula: C7H13NO2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Skugor, Maja Matanovic published the artcileSynthesis and biological activity of 4”-O-acyl derivatives of 14- and 15-membered macrolides linked to ω-quinolone-carboxylic unit, Name: Ethyl 3-(dimethylamino)acrylate, the publication is Bioorganic & Medicinal Chemistry (2010), 18(17), 6547-6558, database is CAplus and MEDLINE.

The synthesis and antimicrobial activity of a new class of macrolide antibiotics which consist of a macrolide scaffold and a quinolone unit covalently connected by an appropriate linker are described. Optimization of several synthetic steps and structural properties of lead compound 26 are discussed. Promising antibacterial properties of this compound and some of its analogs are reported.

Bioorganic & Medicinal Chemistry published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C9H17NO, Name: Ethyl 3-(dimethylamino)acrylate.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Jana, Kalipada published the artcileAllylboronic Esters as Acceptors in Radical Addition, Boron 1,2-Migration, and Trapping Cascades, SDS of cas: 624-49-7, the publication is Organic Letters (2022), 24(4), 1100-1104, database is CAplus and MEDLINE.

Radical 1,3-carboheteroarylation and 1,3-hydroalkylation of allylboronic esters comprising a 1,2-B shift is reported. Allylboronic esters are generally used in synthesis as allylation reagents where the boronic ester moiety gets lost. In the introduced cascades, alkyl boronic esters were obtained with the B entity remaining in the product. The carboheteroarylation of the allylboronic esters are conducted without metal catalyst and the 1,3-hydroalkylation is achieved using Fe catalysis. Both reactions work efficiently under mild conditions.

Organic Letters published new progress about 624-49-7. 624-49-7 belongs to esters-buliding-blocks, auxiliary class Inhibitor,Natural product, name is Dimethyl fumarate, and the molecular formula is C6H8O4, SDS of cas: 624-49-7.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Xia, Yong published the artcileDiversity-Oriented Desulfonylative Functionalization of Alkyl Allyl Sulfones, HPLC of Formula: 19788-49-9, the publication is Angewandte Chemie, International Edition (2019), 58(29), 9836-9840, database is CAplus and MEDLINE.

The diversity-oriented desulfonylative functionalization of alkyl allyl sulfones with various sulfone-type reagents by radical chem. has been developed. The readily installed allylsulfonyl moiety acts as a C-radical precursor, which is substituted by various functionalities using sulfur-based radical trapping reagents. The generality of this approach is documented by the successful desulfonylative alkynylation, azidation, trifluoromethylthiolation, sulfenylation, trifluoromethylselenylation, halogenation, and deuteration. The method is compatible with a wide range of functional groups. Considering the deuteration, products are obtained in good yields with a high level of deuterium incorporation.

Angewandte Chemie, International Edition published new progress about 19788-49-9. 19788-49-9 belongs to esters-buliding-blocks, auxiliary class Thiol,Aliphatic hydrocarbon chain,Ester, name is Ethyl 2-mercaptopropanoate, and the molecular formula is C13H18N2, HPLC of Formula: 19788-49-9.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Yu, Xiu-yue published the artcileA new A₃B zinc(II)-porphyrin ligand and its ruthenium(II) complex: synthesis, photophysical properties and photocatalytic applications, SDS of cas: 30414-53-0, the publication is Journal of Molecular Structure (2021), 130358, database is CAplus.

Porphyrins and metalloporphyrins (or porphyrin coordination complexes) have been wildly investigated as photocatalysts in recent years. Herein we synthesized two new A₃B porphyrins, a new asym. A₃B zinc-porphyrin ligand with peripheral chelate group (pyridine dicarboxylate), and a ruthenium(II) complex of the porphyrin ligand. Their photo-phys. properties were characterized and investigated by UV-visible and fluorescent emission. The modeling of the mol. structures was optimized by DFT theor. calculation All porphyrin compounds exhibited strong absorbance at the Soret bands and Q bands. The free base of porphyrin possessed a higher quantum yield and a longer life time than the other two zinc-porphyrins and ruthenium-porphyrin in terms of fluorescence. Furthermore, the ruthenium-porphyrin complex can be used as a promising photocatalyst under visible light for two kinds of organic reactions: ketone-related oxidative aminothiocyanation (above 90% yield) and indole-related oxidative thiocyanation (around 80% yield) with a remarkable low amount (0.1 mmol %).

Journal of Molecular Structure published new progress about 30414-53-0. 30414-53-0 belongs to esters-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Ketone,Ester, name is Methyl 3-oxovalerate, and the molecular formula is Al2H32O28S3, SDS of cas: 30414-53-0.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics

Gompper, Rudolf published the artcileThe allopolarization principle and its applications. 1. Acceptor-substituted allyl cations as ambifunctional electrophiles, Formula: C7H13NO2, the publication is Angewandte Chemie (1978), 90(10), 808-10, database is CAplus.

Vinamidinium salts [I; R = H, Me, Ph, CO₂Et, CO₂Me; R¹ = H, Me, Ph, Me₂N, Cl; R² = CO₂Et, CO₂Me, COPh, (MeO)₂CH] are stable to hydrolysis at room temperature Treatment of I [R = R¹ = H; R² = CO₂Et, COPh (II and III)] with NaBH₄ yields R²C(NMe₂):CHCH₂NMe₂ (R² = CO₂Et, COPh). R²C(NMe₂):CHCH:CPhCN (R² as above) are prepared by reaction of II and III with benzyl cyanide (EtOH/NaOEt). II reacts with [PhCH:NCHCO₂Et]^– K⁺ to yield IV.

Angewandte Chemie published new progress about 924-99-2. 924-99-2 belongs to esters-buliding-blocks, auxiliary class Alkenyl,Amine,Aliphatic hydrocarbon chain,Ester, name is Ethyl 3-(dimethylamino)acrylate, and the molecular formula is C7H13NO2, Formula: C7H13NO2.

Referemce:
https://en.wikipedia.org/wiki/Ester,
Ester – an overview | ScienceDirect Topics