M.W=100-150 Archives - Page 104 of 148

Zhang, Rui team published research in Green Chemistry in 2021 | 611-13-2

611-13-2, Methyl 2-furoate has been identified as one of the volatile flavor compounds in tequila, okra, berrycactus and black currant juice.
Methyl 2-furoate, also known as fema 2703 or methyl pyromucate, belongs to the class of organic compounds known as furoic acid esters. These are ester derivatives of furoic acid. Methyl 2-furoate is soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Within the cell, methyl 2-furoate is primarily located in the cytoplasm. Methyl 2-furoate is a sweet, fruity, and fungal tasting compound that can be found in a number of food items such as cocoa and cocoa products, potato, tamarind, and fruits. This makes methyl 2-furoate a potential biomarker for the consumption of these food products.
Methyl 2-furoate is a reactive compound that belongs to the family of sesquiterpene lactones. It has been shown to have phosphotungstic acid and hydrochloric acid reactivity, as well as nitrous and water vapor sensitivity. Methyl 2-furoate also reacts with radiation, which can be used for structural analysis. The compound is an intermediate in the synthesis of pluronic p123, which is used in fabricating biomedical devices. Methyl 2-furoate has been shown to have anti-inflammatory properties through its inhibitory effect on prostaglandin synthesis., Computed Properties of 611-13-2

Ester is a chemical compound derived from an oxoacid (organic or inorganic) in which at least one –OH hydroxyl group is replaced by an –O– alkyl (alkoxy) group, 611-13-2, formula is C6H6O3, Name is Methyl furan-2-carboxylate. as in the substitution reaction of a carboxylic acid and an alcohol. Computed Properties of 611-13-2.

Zhang, Rui;Yao, Wei-Zhong;Qian, Liang;Sang, Wei;Yuan, Ye;Du, Min-Chen;Cheng, Hua;Chen, Cheng;Qin, Xin research published 《 A practical and sustainable protocol for direct amidation of unactivated esters under transition-metal-free and solvent-free conditions》, the research content is summarized as follows. In this paper, a NaOtBu-mediated synthesis approach was developed for direct amidation of unactivated esters RC(O)OR¹ (R = Ph, pyridin-2-yl, cyclopropyl, Me, pyrazin-2-yl, etc.; R¹ = Me, Et, Ph, etc.) with amines R²R³NH (R² = Ph, n-hexyl, benzyl, etc.; R³ = H, Me; R²R³ = -(CH₂)₅-, -(CH₂)₂O(CH₂)₂-) under transition-metal-free and solvent-free conditions, affording a series of amides R(CO)NR²R³ in good to excellent yields at room temperature In particular, an environmentally friendly and practical workup procedure, which circumvents the use of organic solvents and chromatog. in most cases, was disclosed. Moreover, the gram-scale production of representative products R(CO)NR²R³ (R = Ph, R² = Ph, 2-phenylethyl, R³ = H; R = Me, R² = Ph, R³ = H) was efficiently realized by applying operationally simple, sustainable and practical procedures. Furthermore, this approach was also applicable to the synthesis of valuable mols. such as moclobemide (a powerful antidepressant), benodanil and fenfuram (two com. agricultural fungicides). These results demonstrate that this protocol has the potential to streamline amide synthesis in industry. Meanwhile, quant. green metrics of all the target products were evaluated, implying that the present protocol is advantageous over the reported ones in terms of environmental friendliness and sustainability. Finally, addnl. experiments and computational calculations were carried out to elucidate the mechanistic insight of this transformation, and one plausible mechanism was provided on the basis of these results and the related literature reports.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhang, Yumeng team published research in International Dairy Journal in 2021 | 611-13-2

Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. 611-13-2, formula is C6H6O3, Name is Methyl furan-2-carboxylate. They perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Product Details of C6H6O3.

Zhang, Yumeng;Yi, Shengnan;Lu, Jing;Pang, Xiaoyang;Xu, Xiaoxi;Lv, Jiaping;Zhang, Shuwen research published 《 Effect of different heat treatments on the Maillard reaction products, volatile compounds and glycation level of milk》, the research content is summarized as follows. In this study, the formation of Maillard reaction products and the Maillard reaction sites of milk proteins were studied under different heat treatment conditions. Fifteen samples heated at 75, 90, 105, 120 or 135°C for 5, 15 or 30 s were selected to investigate the effects of different heat treatment conditions on the Maillard reaction products volatile compounds and protein glycation degree. The contents of fluorescence intensity, furosine, lactulose, and 5-hydroxymethylfural were pos. associated with the heat temperature and treatment time. Compared with that of raw milk, the number of glycated proteins increased from 14 to 49 in the milk samples heated at 135°C for 5 s, and the number of binding sites increased from 47 to 166. These results advance current knowledge about the effect of different heat treatments on the degree of the Maillard reaction and the sensory quality and glycation level of milk.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ye, Mingchun team published research in Applied Catalysis, A: General in 2021 | 611-13-2

Glycerides are fatty acid esters of glycerol; they are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. 611-13-2, formula is C6H6O3, Name is Methyl furan-2-carboxylate. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Quality Control of 611-13-2.

Ye, Mingchun;Kuo, Mi Jen;Lobo, Raul F. research published 《 Oxidative coupling of 2-methyl furoate: A scalable synthesis of dimethyl 2,2′-bifuran-5,5′-dicarboxylate》, the research content is summarized as follows. We report an investigation of the homogeneous Pd-catalyzed oxidative homocoupling of Me 2-furoate with mol. oxygen as oxidant. Conditions were identified that produce acceptable yield (11.4%), good selectivity (85%) and ultra-high turn-over-frequency (TOF, 544 h^-1). The product, di-Me 2,2′-bifuran-5,5′-dicarboxylate, precipitates in nearly pure form upon cooling the reaction mixture Kinetic and mechanistic investigations showed the reaction followed the so-called bimetallic mechanism.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yin, Defeng team published research in RSC Advances in 2021 | 611-13-2

HPLC of Formula: 611-13-2, Methyl 2-furoate has been identified as one of the volatile flavor compounds in tequila, okra, berrycactus and black currant juice.
Methyl 2-furoate, also known as fema 2703 or methyl pyromucate, belongs to the class of organic compounds known as furoic acid esters. These are ester derivatives of furoic acid. Methyl 2-furoate is soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Within the cell, methyl 2-furoate is primarily located in the cytoplasm. Methyl 2-furoate is a sweet, fruity, and fungal tasting compound that can be found in a number of food items such as cocoa and cocoa products, potato, tamarind, and fruits. This makes methyl 2-furoate a potential biomarker for the consumption of these food products.
Methyl 2-furoate is a reactive compound that belongs to the family of sesquiterpene lactones. It has been shown to have phosphotungstic acid and hydrochloric acid reactivity, as well as nitrous and water vapor sensitivity. Methyl 2-furoate also reacts with radiation, which can be used for structural analysis. The compound is an intermediate in the synthesis of pluronic p123, which is used in fabricating biomedical devices. Methyl 2-furoate has been shown to have anti-inflammatory properties through its inhibitory effect on prostaglandin synthesis., 611-13-2.

Yin, Defeng;Zheng, Yanxia;Yang, Lixi;Li, Shuyue;Zhu, Daqing;Guo, Yafei;Zuo, Cuncun;Li, Yuchao;Huang, Haofei;Wang, Ming research published 《 Oxidative esterification of renewable furfural on cobalt dispersed on ordered porous nitrogen-doped carbon》, the research content is summarized as follows. A series of highly dispersed cobalt-based catalysts on N-doped ordered porous carbon (Co-NOPC) were synthesized using the sacrificial-template method. MCM-41, ZSM-5 and SBA-15 were employed as hard templates with 2,2′-bipyridine as the ligand. The phys. and chem. properties of the Co-NOPC catalyst were characterized by Raman, XRD, SEM, TEM, EDX, ICP, BET, XPS. Co-NOPC had been proven to be a highly efficient catalyst for oxidative esterification of furfural (FUR) to Me 2-furoate without alk. additives. Catalytic performance was correlated to the dispersed cobalt, porous structure and sp. surface area. The relationship between oxygen activation and the strong interaction of cobalt and pyridine nitrogen were confirmed by XPS. Catalytic performance enhancement mechanisms were correlated with the redistribution of electrons at the interface between carbon material and cobalt atoms through the mol. dynamics method and a reaction mechanism was also proposed. The optimized catalysts showed outstanding catalytic activity and stability and no obvious decrease in activity was found after 6 cycles with 99.6% FUR conversion and 96% Me 2-furoate selectivity.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yin, Xiaoyu team published research in LWT–Food Science and Technology in 2021 | 611-13-2

Yin, Xiaoyu;Wen, Rongxin;Sun, Fangda;Wang, Yan;Kong, Baohua;Chen, Qian research published 《 Collaborative analysis on differences in volatile compounds of Harbin red sausages smoked with different types of woodchips based on gas chromatography-mass spectrometry combined with electronic nose》, the research content is summarized as follows. In this study, the volatile profiles of Harbin red sausages smoked with pear, oak, apple and beech woodchips were evaluated using the combination of solid-phase microextraction gas chromatog.-mass spectrometry (SPME-GC/MS) and electronic nose (E-nose). Comparisons of the color, texture profile and sensory attributes were also conducted. The E-nose data and GC/MS data were analyzed by principal component anal. (PCA), resp. The correlation between E-nose sensor responses and volatile compounds was evaluated with partial least squares regression (PLSR). The results showed that the smoking process played an important role in the formation of volatile compounds of Harbin red sausage. The smoking process caused an increase in the intensity of smoky odor, and the sausage smoked with different woodchips showed higher smoky odor compared with the unsmoked sausage (P < 0.05). A total of 87 volatile compounds were identified by GC/MS. According to the odor activity values, the characteristic odor of the Harbin red sausages mainly resulted from 22 volatile compounds PCA of the volatile compounds and E-nose sensors could effectively differentiate sausages that were unsmoked and sep. smoked with different woodchips. Furthermore, the PLSR results (P < 0.05, Q² = 0.619) indicated that there was a high correlation between the E-nose sensors and volatile compounds

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yin, Xiaoyu team published research in Meat Science in 2021 | 611-13-2

Safety of Methyl furan-2-carboxylate, Methyl 2-furoate has been identified as one of the volatile flavor compounds in tequila, okra, berrycactus and black currant juice.
Methyl 2-furoate, also known as fema 2703 or methyl pyromucate, belongs to the class of organic compounds known as furoic acid esters. These are ester derivatives of furoic acid. Methyl 2-furoate is soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Within the cell, methyl 2-furoate is primarily located in the cytoplasm. Methyl 2-furoate is a sweet, fruity, and fungal tasting compound that can be found in a number of food items such as cocoa and cocoa products, potato, tamarind, and fruits. This makes methyl 2-furoate a potential biomarker for the consumption of these food products.
Methyl 2-furoate is a reactive compound that belongs to the family of sesquiterpene lactones. It has been shown to have phosphotungstic acid and hydrochloric acid reactivity, as well as nitrous and water vapor sensitivity. Methyl 2-furoate also reacts with radiation, which can be used for structural analysis. The compound is an intermediate in the synthesis of pluronic p123, which is used in fabricating biomedical devices. Methyl 2-furoate has been shown to have anti-inflammatory properties through its inhibitory effect on prostaglandin synthesis., 611-13-2.

Yin, Xiaoyu;Lv, Yichao;Wen, Rongxin;Wang, Yan;Chen, Qian;Kong, Baohua research published 《 Characterization of selected Harbin red sausages on the basis of their flavour profiles using HS-SPME-GC/MS combined with electronic nose and electronic tongue》, the research content is summarized as follows. In this study, volatile profiles and taste properties of Harbin red sausages prepared with traditional and conventional processing methods were evaluated using solid-phase microextraction gas chromatog.-mass spectrometry (SPME-GC/MS) coupled with electronic nose (E-nose) and electronic tongue (E-tongue). Four varieties of traditional sausages and four varieties of conventional sausages were selected. A total of 131 volatiles were identified, of which 50 were found in all sausages, and of which 77 were significantly different between traditional sausages and conventional sausages. The total contents of aldehydes (211.32μg/kg), ketones (404.28μg/kg), phenols (1795.40μg/kg) and furans (928.73μg/kg) in the traditional sausages were significantly higher than those in the conventional sausages (P < 0.05). The results of GC/MS coupled with E-nose based on principal component anal. could discriminate the sausages well, but the E-tongue could not clearly distinguish them. The results of partial least square regression (P < 0.05, Q² = 0.659) indicated that there was a high correlation between the E-nose sensors and volatiles of Harbin red sausages.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Yuan, Jiaqi team published research in RSC Advances in 2021 | 611-13-2

Electric Literature of 611-13-2, Methyl 2-furoate has been identified as one of the volatile flavor compounds in tequila, okra, berrycactus and black currant juice.
Methyl 2-furoate, also known as fema 2703 or methyl pyromucate, belongs to the class of organic compounds known as furoic acid esters. These are ester derivatives of furoic acid. Methyl 2-furoate is soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Within the cell, methyl 2-furoate is primarily located in the cytoplasm. Methyl 2-furoate is a sweet, fruity, and fungal tasting compound that can be found in a number of food items such as cocoa and cocoa products, potato, tamarind, and fruits. This makes methyl 2-furoate a potential biomarker for the consumption of these food products.
Methyl 2-furoate is a reactive compound that belongs to the family of sesquiterpene lactones. It has been shown to have phosphotungstic acid and hydrochloric acid reactivity, as well as nitrous and water vapor sensitivity. Methyl 2-furoate also reacts with radiation, which can be used for structural analysis. The compound is an intermediate in the synthesis of pluronic p123, which is used in fabricating biomedical devices. Methyl 2-furoate has been shown to have anti-inflammatory properties through its inhibitory effect on prostaglandin synthesis., 611-13-2.

Yuan, Jiaqi;Zhang, Xiaofei;Yang, Chunhao research published 《 Regioselective Pd-catalyzed α-alkylation of furans using alkyl iodides》, the research content is summarized as follows. Herein, direct alkylation of the C-H bond at the α-position of furans I (R = H, methoxycarbonyl, Ph, [4-[(tert-butoxy)carbonyl]piperazin-1-yl]carbonyl, etc.; R¹ = H, Me; RR¹ = -CH=CH-CH=CH-; R² = H, CHO; R³ = H) catalyzed by palladium catalyst is reported. This protocol targets α-alkylfurans I (R³ = oxan-4-yl, butan-2-yl, cyclohexyl, etc.), achieving moderate to good yields under very practical reaction conditions. With a broad scope of substrates and good functional group tolerance, this method has promising utility in medicinal chem.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Zhan, Zhen Z. team published research in ChemistrySelect in 2021 | 611-13-2

Polyesters are important plastics, with monomers linked by ester moieties. Phosphoesters form the backbone of DNA molecules. 611-13-2, formula is C6H6O3, Name is Methyl furan-2-carboxylate.Nitrate esters, such as nitroglycerin, are known for their explosive properties. HPLC of Formula: 611-13-2.

Zhan, Zhen Z.;He, Jian P.;Jiang, Peng B.;Zhang, Ming M.;Wang, He S.;Luo, Nan;Huang, Guo S. research published 《 Cu(II)-Catalyzed Synthesis of 2,3,6-Trisubstituted Pyridines from Saturated Ketone and Alkynones/1,3-Dicarbonyl Compounds》, the research content is summarized as follows. In this work, a highly efficient one-pot synthesis of 2,3,6-trisubstituted pyridines has been achieved through copper-catalyzed condensation reaction of saturated ketones and alkynones/1,3-dicarbonyl compounds This method provided the convenient routes to the synthesis of 2,3,6-trisubstituted pyridines with good functional group tolerance. Compared with previous works, this method does not require the synthesis of enamine in advance.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Xie, Yi team published research in Chinese Journal of Chemistry in 2021 | 611-13-2

Xie, Yi;Yu, Bin;Luo, Jiajun;Yin, Biaolin;Jiang, Huanfeng research published 《 Synthesis of [2,2′]Bifuranyl-5,5′-dicarboxylic acid esters via reductive homocoupling of 5-bromofuran-2-carboxylates using alcohols as green reductants》, the research content is summarized as follows. An environmentally benign and cost-effective protocol for the synthesis of valuable bifuranyl dicarboxylates, starting with α-bromination of readily accessible furan-2-carboxylates by LiBr and K₂S₂O₈ are described. Furthermore, the bromination intermediate product 5-bromofuran-2-carboxylates were then conducted in a palladium-catalyzed reductive homocoupling reactions in the presence of alcs. to afford bifuranyl dicarboxylates. One of the final products in this protocol, [2,2′]bifuran-5,5′-dicarboxylic acid esters were essential monomers of poly(ethylene bifuranoate), which are served as a green and versatile alternative polymer for traditional poly(ethylene terephthalate) that was currently common in tech. plastics.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Xu, Dan team published research in Chemical Engineering Journal (Amsterdam, Netherlands) in 2022 | 611-13-2

Xu, Dan;Li, Jianfeng;Li, Boyang;Zhao, Huacheng;Zhu, Hanghang;Kou, Jinfang;Zhang, Fengwei;Dong, Zhengping;Ma, Jiantai research published 《 Selective oxidation of alcohols to high value-added carbonyl compounds using air over Co-Co₃O₄@NC catalysts》, the research content is summarized as follows. The sustainable catalytic transformation of alcs. to high value-added fine chems. is a significant and challenging research topic. Herein, a set of nitrogen-doped carbon encapsulated Co-based catalysts (Co-Co₃O₄@NC-T) were prepared by using low-cost dicyandiamide, glyoxal and cobalt nitrate as precursors. The obtained catalysts were utilized for the selective oxidation of alcs. to high value-added esters and carboxylic acids with air as the oxygen source and displayed wide applicability for the oxidation of both aromatic and aliphatic alcs. Based on the controlled experiments, the protective effect of N-doped carbon structure and the synergistic effect between Co core and Co₃O₄ species guaranteed the high reaction conversion and selectivity. Benefitting from heterogeneity and magnetism of the catalyst, it can be easily recycled and reused for long-term stability. Reasonable mechanisms of selective oxidation reaction were proposed through EPR anal. and controlled experiments The present work provides a facile strategy for potential large-scale preparation of heterogeneous catalyst for sustainable and green catalytic transformations.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics