Tag: M.W=100-150

Wang, Meilin; Yao, Dawei; Li, Antai; Yang, Youwei; Lv, Jing; Huang, Shouying; Wang, Yue; Ma, Xinbin published the artcile< Enhanced Selectivity and Stability of Cu/SiO2 Catalysts for Dimethyl Oxalate Hydrogenation to Ethylene Glycol by Using Silane Coupling Agents for Surface Modification>, Recommanded Product: Ethyl 2-hydroxyacetate, the main research area is selectivity copper SiO2 catalyst dimethyl oxalate hydrogenation.

Hydrogenation of di-Me oxalate (DMO) is one of the key steps in the route of ethylene glycol (EG) production from syngas. Cu/SiO2 catalysts prepared by ammonia evaporation method are reported to present excellent catalytic performance for selective DMO hydrogenation and used in the industry. However, the selectivity of EG and the long-term stability of catalysts still require improvement. Herein, we used silane coupling agents to selectively and efficiently cover the surface isolated hydroxyl groups on Cu/SiO2 by post-grafting method, which exhibited a prominently promotion effect on reducing the selectivity of byproducts (C3-C4OH) and enhancing the catalytic stability. Characterization results suggested that both the d. and intensity of the basic sites decreased significantly after the coverage of hydroxyl groups, resulting in the reduction of C3-C4OH selectivity, thus increasing the EG selectivity. Meanwhile, the coke and blocked pore structure induced by excessive Me glycolate (MG) adsorption and polymerization on surface hydroxyl groups could be the main reason for catalyst deactivation. After the surface modification, MG desorption was greatly facilitated, which improved the stability in DMO hydrogenation. Furthermore, the effect of different silane coupling agents ended with amino or alkyl groups was studied as well. These insights concerning the effect of covering hydroxyl groups by silane coupling agents on selectivity and stability may provide practical guidance for the design and fabrication of Cu/SiO2 catalysts for the industrial application.

Industrial & Engineering Chemistry Research published new progress about Binding energy. 623-50-7 belongs to class esters-buliding-blocks, and the molecular formula is C4H8O3, Recommanded Product: Ethyl 2-hydroxyacetate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Meyer, Stephanie; Haefliger, Joel; Schaefer, Michael; Molloy, John J.; Daniliuc, Constantin G.; Gilmour, Ryan published the artcile< A Chiral Pentafluorinated Isopropyl Group via Iodine(I)/(III) Catalysis>, Product Details of C6H12O3, the main research area is fluoride enantioselective synthesis difluorination trifluoromethyl styrene catalyst; regioselective synthesis difluoronation; agrochemistry; bioisostere; conformation; fluorine; organocatalysis.

An I(I)/(III) catalysis strategy to construct an enantioenriched fluorinated isostere of the iPr group is reported. The difluorination of readily accessible α-CF3-styrenes is enabled by the in situ generation of a chiral ArIF2 species to forge a stereocentre with the substituents F, CH2F and CF3 (up to 95%, >20:1 vicinal:geminal difluorination). The replacement of the metabolically labile benzylic proton results in a highly preorganised scaffold as was determined by X-ray crystallog. (π→σ* and stereoelectronic gauche σ→σ* interactions). A process of catalyst editing is disclosed in which preliminary validation of enantioselectivity is placed on a structural foundation.

Angewandte Chemie, International Edition published new progress about Asymmetric catalysis. 24347-63-5 belongs to class esters-buliding-blocks, and the molecular formula is C6H12O3, Product Details of C6H12O3.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Wang, Lei; Zhou, Xia; Lu, Hui; Mu, Xianfu; Jin, Linhong published the artcile< Synthesis and antibacterial evaluation of novel 1,3,4-oxadiazole derivatives containing sulfonate/carboxylate moiety>, Category: esters-buliding-blocks, the main research area is sulfonate carboxylate oxadiazole preparation agrochem antibacterial activity; 1,3,4-oxadiazole derivatives; antibacterial activity; scanning electron microscopy; xanthomonas axonopodis pv. Citri; xanthomonas oryzae pv. oryzae.

Novel sulfonate/carboxylate functionalized 1,3,4-oxadiazole derivatives I (R1 = Me, Et, 2-fluoroethyl; R2 = Ph, 2-fluorophenyl, 4-chlorophenyl, etc.) and II [R1 = Me; R3 = Ph, 4-bromophenyl, N(CH3)2, etc.] were synthesized and evaluated for their antibacterial activities. Antibacterial activity against two phytopathogens, Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas axonopodis pv. citri (Xac), was assayed in vitro. The preliminary results indicated that ten compounds including I [R1 = Ph, R2 = Me (A); R1 = 4-fluorophenyl, R2 = Me (B); R1 = 4-chlorophenyl, R2 = Me (C); R1 = 4-bromophenyl, R2 = Me (D); R1 = 4-fluorophenyl, R2 = Et; R1 = 4-chlorophenyl, R2 = Et; R1 = 4-bromophenyl, R2 = Et; R1 = 4-fluorophenyl, R2 = 2-fluoroethyl; R1 = 4-chlorophenyl, R2 = 2-fluoroethyl; R1 = 4-bromophenyl, R2 = 2-fluoroethyl] had good antibacterial activity against Xoo, with EC50 values ranging from 50.1-112.5μM, which was better than those of Bismerthiazol (253.5μM) and thiadiazole copper (467.4μM). Meanwhile, compounds(A), (B), (C), (D) demonstrated good inhibitory effect against Xanthomonas axonopodis pv. citri with EC50 values around 95.8-155.2μM which were better than those of bismerthiazol (274.3μM) and thiadiazole copper (406.3μM). In addition, in vivo protection activity of compounds (B), (C) against rice bacterial leaf blight was 68.6% and 62.3%, resp., which were better than bismerthiazol (49.6%) and thiadiazole copper (42.2%). Curative activity of compounds (B), (C) against rice bacterial leaf blight was 62.3% and 56.0%, which were better than bismerthiazol (42.9%) and thiadiazole copper (36.1%). Through SEM (SEM) anal., it was observed that compound (B) caused the cell membrane of Xanthomonas oryzae pv. oryzae ruptured or deformed. The present results indicated novel derivatives of 4-Ph sulfonate Me 1,3,4-oxadiazole I might be potential antibacterial agents.

Molecules published new progress about Acid chlorides Role: RCT (Reactant), RACT (Reactant or Reagent). 623-50-7 belongs to class esters-buliding-blocks, and the molecular formula is C4H8O3, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Haefliger, Joel; Livingstone, Keith; Daniliuc, Constantin G.; Gilmour, Ryan published the artcile< Difluorination of α-(bromomethyl)styrenes via I(I)/I(II) catalysis: facile access to electrophilic linchpins for drug discovery>, Category: esters-buliding-blocks, the main research area is bromomethyl styrene catalysis electrophilic linchpin drug discovery difluorination.

Simple α-(bromomethyl)styrenes can be processed to a variety of 1,1-difluorinated electrophilic building blocks via I(I)/I(III) catalysis. This inexpensive main group catalysis strategy employs p-TolI as an effective organocatalyst when combined with Selectfluor and simple amine·HF complexes. Modulating Bronsted acidity enables simultaneous geminal and vicinal difluorination to occur, thereby providing a platform to generate multiply fluorinated scaffolds for further downstream derivatization. The method facilitates access to a tetrafluorinated API candidate for the treatment of amyotrophic lateral sclerosis. Preliminary validation of an enantioselective process is disclosed to access α-phenyl-β-difluoro-γ-bromo/chloro esters.

Chemical Science published new progress about Amyotrophic lateral sclerosis. 24347-63-5 belongs to class esters-buliding-blocks, and the molecular formula is C6H12O3, Category: esters-buliding-blocks.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Bekele, Tefsit; Shah, Meha H.; Wolfer, Jamison; Abraham, Ciby J.; Weatherwax, Anthony; Lectka, Thomas published the artcile< Catalytic, Enantioselective [4 + 2]-Cycloadditions of Ketene Enolates and o-Quinones: Efficient Entry to Chiral, α-Oxygenated Carboxylic Acid Derivatives>, Safety of (R)-Methyl 2-hydroxybutanoate, the main research area is cinchona alkaloid catalyst enantioselective cycloaddition quinone ketene enolate.

The authors report catalytic, enantioselective [4 + 2]-cycloadditions of o-quinones with ketene enolates (derived from readily available acid chlorides) using cinchona alkaloid derivatives as catalysts to produce products in high enantiomeric excess (ee) and good to excellent yields. The thermodn. driving force for these reactions is due in part to the restoration of aromaticity to the products. The resulting chiral, bicycloadducts, e.g. I, can be synthetically manipulated in a variety of useful ways, for example to provide a flexible synthesis of α-oxygenated carboxylic acid derivatives

Journal of the American Chemical Society published new progress about [4+2] Cycloaddition reaction. 73349-07-2 belongs to class esters-buliding-blocks, and the molecular formula is C5H10O3, Safety of (R)-Methyl 2-hydroxybutanoate.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Glycerides are fatty acid esters of glycerol; they are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. 611-13-2, formula is C6H6O3, Name is Methyl furan-2-carboxylate. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Quality Control of 611-13-2.

Zhao, Xin;Wang, Fengliang;Kong, Xiang-Peng;Fang, Ruiqi;Li, Yingwei research published 《 Dual-Metal Hetero-Single-Atoms with Different Coordination for Efficient Synergistic Catalysis》, the research content is summarized as follows. Rationally tailoring the coordination environments of metal single atoms (SAs) is an effective approach to promote their catalytic performances, which, however, remains as a challenge to date. Here, we report a novel misplaced deposition strategy for the fabrication of differently coordinated dual-metal hetero-SAs. Systematic characterization results imply that the as-synthesized dual-metal hetero-SAs (exemplified by Cu and Co) are affixed to a hierarchical carbon support via Cu-C₄ and Co-N₄ coordination bonds. D. functional theory studies reveal that the strong synergistic interactions between the asym. deployed CuC₄ and CoN₄ sites lead to remarkably polarized charge distributions, i.e., electron accumulation and deficiency around CuC₄ and CoN₄ sites, resp. The obtained CuC₄/CoN₄@HC catalyst exhibits significantly enhanced capability in substrate adsorption and O₂ activation, achieving superior catalytic performances in the oxidative esterification of aromatic aldehydes in comparison with the Cu- and Co-based SA counterparts.

Quality Control of 611-13-2, Methyl 2-furoate has been identified as one of the volatile flavor compounds in tequila, okra, berrycactus and black currant juice.
Methyl 2-furoate, also known as fema 2703 or methyl pyromucate, belongs to the class of organic compounds known as furoic acid esters. These are ester derivatives of furoic acid. Methyl 2-furoate is soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Within the cell, methyl 2-furoate is primarily located in the cytoplasm. Methyl 2-furoate is a sweet, fruity, and fungal tasting compound that can be found in a number of food items such as cocoa and cocoa products, potato, tamarind, and fruits. This makes methyl 2-furoate a potential biomarker for the consumption of these food products.
Methyl 2-furoate is a reactive compound that belongs to the family of sesquiterpene lactones. It has been shown to have phosphotungstic acid and hydrochloric acid reactivity, as well as nitrous and water vapor sensitivity. Methyl 2-furoate also reacts with radiation, which can be used for structural analysis. The compound is an intermediate in the synthesis of pluronic p123, which is used in fabricating biomedical devices. Methyl 2-furoate has been shown to have anti-inflammatory properties through its inhibitory effect on prostaglandin synthesis., 611-13-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ester is a chemical compound derived from an oxoacid (organic or inorganic) in which at least one –OH hydroxyl group is replaced by an –O– alkyl (alkoxy) group, 611-13-2, formula is C6H6O3, Name is Methyl furan-2-carboxylate. as in the substitution reaction of a carboxylic acid and an alcohol. Product Details of C6H6O3.

Zhou, Changjian;Sun, Rong;Zhang, Yuting;Xiong, Biao;Dai, Hui;Dai, Yong research published 《 Co-N-Si/AC Catalyst for Aerobic Oxidation of Benzyl Alcohols to Esters under Mild Conditions》, the research content is summarized as follows. A stable, earth-abundant, reusable cobalt-based heterogeneous catalyst is developed for the oxidative esterification of alcs. RCH₂OH (R = Ph, naphthalen-1-yl, thiophen-2-yl, etc.) under ambient conditions, featuring broad substrate scope, providing good to excellent product yields. This protocol enables easy recyclability of the catalyst, measured up to five times without significant loss of efficiency. The active sites of Co-N-Si/AC are proposed to be Co-N species.

Product Details of C6H6O3, Methyl 2-furoate has been identified as one of the volatile flavor compounds in tequila, okra, berrycactus and black currant juice.
Methyl 2-furoate, also known as fema 2703 or methyl pyromucate, belongs to the class of organic compounds known as furoic acid esters. These are ester derivatives of furoic acid. Methyl 2-furoate is soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Within the cell, methyl 2-furoate is primarily located in the cytoplasm. Methyl 2-furoate is a sweet, fruity, and fungal tasting compound that can be found in a number of food items such as cocoa and cocoa products, potato, tamarind, and fruits. This makes methyl 2-furoate a potential biomarker for the consumption of these food products.
Methyl 2-furoate is a reactive compound that belongs to the family of sesquiterpene lactones. It has been shown to have phosphotungstic acid and hydrochloric acid reactivity, as well as nitrous and water vapor sensitivity. Methyl 2-furoate also reacts with radiation, which can be used for structural analysis. The compound is an intermediate in the synthesis of pluronic p123, which is used in fabricating biomedical devices. Methyl 2-furoate has been shown to have anti-inflammatory properties through its inhibitory effect on prostaglandin synthesis., 611-13-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Glycerides are fatty acid esters of glycerol; they are important in biology, being one of the main classes of lipids and comprising the bulk of animal fats and vegetable oils. 611-13-2, formula is C6H6O3, Name is Methyl furan-2-carboxylate. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Product Details of C6H6O3.

Zubar, Viktoriia;Lichtenberger, Niels;Schelwies, Mathias;Oeser, Thomas;Hashmi, A. Stephen K.;Schaub, Thomas research published 《 Manganese-Catalyzed Hydrogenation of Sclareolide to Ambradiol》, the research content is summarized as follows. The hydrogenation of (+)-Sclareolide to (-)-ambradiol catalyzed by a manganese pincer complex is reported. The hydrogenation reaction is performed with an air- and moisture-stable manganese catalyst and proceeds under relatively mild reaction conditions at low manganese and base loadings. A range of other esters ROC(O)R¹ (R = Me, Et, t-Bu; R¹ = undecan-1-yl, Ph, furan-2-yl, etc.) and 5-methyloxolan-2-one could be successfully hydrogenated leading to the corresponding alcs. R¹CH₂OH and pentane-1,4-diol in good to quant. yields using this easy-to-make catalyst. A scale-up experiment was performed leading to 99.3% of the isolated yield of (-)-Ambradiol.

Product Details of C6H6O3, Methyl 2-furoate has been identified as one of the volatile flavor compounds in tequila, okra, berrycactus and black currant juice.
Methyl 2-furoate, also known as fema 2703 or methyl pyromucate, belongs to the class of organic compounds known as furoic acid esters. These are ester derivatives of furoic acid. Methyl 2-furoate is soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Within the cell, methyl 2-furoate is primarily located in the cytoplasm. Methyl 2-furoate is a sweet, fruity, and fungal tasting compound that can be found in a number of food items such as cocoa and cocoa products, potato, tamarind, and fruits. This makes methyl 2-furoate a potential biomarker for the consumption of these food products.
Methyl 2-furoate is a reactive compound that belongs to the family of sesquiterpene lactones. It has been shown to have phosphotungstic acid and hydrochloric acid reactivity, as well as nitrous and water vapor sensitivity. Methyl 2-furoate also reacts with radiation, which can be used for structural analysis. The compound is an intermediate in the synthesis of pluronic p123, which is used in fabricating biomedical devices. Methyl 2-furoate has been shown to have anti-inflammatory properties through its inhibitory effect on prostaglandin synthesis., 611-13-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ester is a chemical compound derived from an oxoacid (organic or inorganic) in which at least one –OH hydroxyl group is replaced by an –O– alkyl (alkoxy) group, 611-13-2, formula is C6H6O3, Name is Methyl furan-2-carboxylate. as in the substitution reaction of a carboxylic acid and an alcohol. Computed Properties of 611-13-2.

Zhang, Fangcao;Gong, Mingliang;Xie, Hongzhen;Luo, Yunjie research published 《 La(CH₂C₆H₄NMe₂-o)₃-catalyzed reduction of esters to alcohols with pinacolborane》, the research content is summarized as follows. La(CH₂C₆H₄NMe₂-o)₃, a simple and facilely accessible lanthanide complex, can serve as a highly efficient catalyst for the reduction of esters e.g., Me 4-(trifluoromethyl)benzoate with pinacolborane (HBpin), selectively affording alcs. e.g., [4-(trifluoromethyl)phenyl]methanol in good yields under mild conditions. This protocol exhibits good tolerance for many functional groups such as C=C double bond, nitro, halogen, furyl, and thienyl groups. A lanthanum hydride species like [La]-H.HBpin is proposed to play a crucial role in promoting the interaction of esters with HBpin.

Computed Properties of 611-13-2, Methyl 2-furoate has been identified as one of the volatile flavor compounds in tequila, okra, berrycactus and black currant juice.
Methyl 2-furoate, also known as fema 2703 or methyl pyromucate, belongs to the class of organic compounds known as furoic acid esters. These are ester derivatives of furoic acid. Methyl 2-furoate is soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Within the cell, methyl 2-furoate is primarily located in the cytoplasm. Methyl 2-furoate is a sweet, fruity, and fungal tasting compound that can be found in a number of food items such as cocoa and cocoa products, potato, tamarind, and fruits. This makes methyl 2-furoate a potential biomarker for the consumption of these food products.
Methyl 2-furoate is a reactive compound that belongs to the family of sesquiterpene lactones. It has been shown to have phosphotungstic acid and hydrochloric acid reactivity, as well as nitrous and water vapor sensitivity. Methyl 2-furoate also reacts with radiation, which can be used for structural analysis. The compound is an intermediate in the synthesis of pluronic p123, which is used in fabricating biomedical devices. Methyl 2-furoate has been shown to have anti-inflammatory properties through its inhibitory effect on prostaglandin synthesis., 611-13-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Polyesters are important plastics, with monomers linked by ester moieties. Phosphoesters form the backbone of DNA molecules. 611-13-2, formula is C6H6O3, Name is Methyl furan-2-carboxylate.Nitrate esters, such as nitroglycerin, are known for their explosive properties. Related Products of 611-13-2.

Zhang, Lang;Hu, Yingying;Wang, Yan;Kong, Baohua;Chen, Qian research published 《 Evaluation of the flavour properties of cooked chicken drumsticks as affected by sugar smoking times using an electronic nose, electronic tongue, and HS-SPME/GC-MS》, the research content is summarized as follows. This study evaluated the effect of different sugar smoking times on the flavor profiles of chicken drumsticks using an electronic nose (E-nose), electronic tongue (E-tongue), and headspace solid-phase microextraction gas chromatog.-mass spectrometry (HS-SPME/GC-MS). The moisture content, water activity, pH, and L*-value decreased from 71.26% to 65.23%, 0.987 to 0.979, 6.66 to 5.36, and 61.84 to 52.34, resp. (P < 0.05). The a*-value and b*-value increased from 4.96 to 9.65 and 16.61 to 26.45, resp. (P < 0.05) with the increase in smoking times. Seventy-five volatile compounds were identified, and 18 volatile compounds were identified as key odor compounds and among them seven key volatile compounds with variable importance in projection (VIP) >1 were detected. Principal component anal. of E-nose, E-tongue, and HS-SPME/GC-MS indicated that 3-, 4-, and 5-min smoking samples had similar odor and taste profiles. Sensory anal. indicated that the 4-min sample had increased overall acceptability. The correlation anal. of E-nose and key volatile compounds with odor activity value > 1 and VIP > 1 confirmed that W1C, W3C, and W5C sensors were sensitive to aromatic compounds, and W2S sensor was sensitive to ketones. These results may provide guidance for smoked chicken producers to reasonably control flavor formation.

Related Products of 611-13-2, Methyl 2-furoate has been identified as one of the volatile flavor compounds in tequila, okra, berrycactus and black currant juice.
Methyl 2-furoate, also known as fema 2703 or methyl pyromucate, belongs to the class of organic compounds known as furoic acid esters. These are ester derivatives of furoic acid. Methyl 2-furoate is soluble (in water) and an extremely weak basic (essentially neutral) compound (based on its pKa). Within the cell, methyl 2-furoate is primarily located in the cytoplasm. Methyl 2-furoate is a sweet, fruity, and fungal tasting compound that can be found in a number of food items such as cocoa and cocoa products, potato, tamarind, and fruits. This makes methyl 2-furoate a potential biomarker for the consumption of these food products.
Methyl 2-furoate is a reactive compound that belongs to the family of sesquiterpene lactones. It has been shown to have phosphotungstic acid and hydrochloric acid reactivity, as well as nitrous and water vapor sensitivity. Methyl 2-furoate also reacts with radiation, which can be used for structural analysis. The compound is an intermediate in the synthesis of pluronic p123, which is used in fabricating biomedical devices. Methyl 2-furoate has been shown to have anti-inflammatory properties through its inhibitory effect on prostaglandin synthesis., 611-13-2.

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics