Tag: 300-400

On April 7, 2002, Huttenloch, Oliver; Laxman, Eltepu; Waldmann, Herbert published an article.COA of Formula: C19H26N2O3 The title of the article was Combinatorial development of chiral phosphoramidite-ligands for enantioselective conjugate addition reactions. And the article contained the following:

Chiral phosphoramidite ligands embodying bispidine frame work and a binaphthyl phosphoramidite for Cu-catalyzed enantioselective conjugate addition reactions were developed employing principles of combinatorial and solid phase chem. The experimental process involved the reaction of tert-Butyl 7-benzyl-9-oxo-3,7-diazabicyclo[3.3.1]nonane-3-carboxylate(cas: 227940-70-7).COA of Formula: C19H26N2O3

The Article related to combinatorial phosphoramidite ligand enantioselective conjugate addition reaction, Alicyclic Compounds: Cyclohexanes and other aspects.COA of Formula: C19H26N2O3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On April 30, 2020, Olmos-Espejel, Jose J.; Mogica-Garcia, Oscar E.; Duran-Gasca, Gerson J.; Carmona-Lopez, Magaly L. published an article.Reference of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate The title of the article was Methodology for Analysis of UV Filters in Tilapia Using Off-line MSPD Followed by On-line SPE-LC/UV. And the article contained the following:

Abstract: A sensitive method was developed and validated for the determination of UV filters (oxybenzone, octocrylene, 4-methyl-benzylidene camphor, 2-ethylhexyl-4-methoxycinnamate and avobenzone) in tilapia muscle using matrix solid-phase dispersion followed by online solid-phase extraction-liquid chromatog./UV. The validation showed good linearity from 100 to 3600 ng g-1 with r2 values > 0.98. Precision values with relative standard deviations were < 24% for all analytes. The accuracy was evaluated with the recovery of spiked muscle samples, and it ranged between 89 and 96% for most analytes, except 2-ethylhexyl-4-methoxycinnamate. A pos. matrix effect was observed for oxybenzone, so a matrix-matched calibration curve was used for quantitation purposes. This methodol. was applied to incurred samples of fish exposed to the analytes for 3 days (100μg L-1 each). Residual quantities of the contaminants were measured after 24, 48 and 72 h of exposure, and concentrations ranged between 400 and 2900 ng g-1. The developed method was able to quantify all of the target compounds at trace levels. The experimental process involved the reaction of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate(cas: 6197-30-4).Reference of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate

The Article related to uv filter compound tilapia matrix solid dispersion extraction lc, Food and Feed Chemistry: Analysis and other aspects.Reference of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 19, 2017, Je, Goun; Croop, Benjamin; Basu, Sambuddha; Tang, Jialei; Han, Kyu Young; Kim, Yoon-Seong published an article.Quality Control of Bis(2,5-dioxopyrrolidin-1-yl) glutarate The title of the article was Endogenous Alpha-Synuclein Protein Analysis from Human Brain Tissues Using Single-Molecule Pull-Down Assay. And the article contained the following:

Alpha-synuclein (α-SYN) is a central mol. in Parkinson’s disease pathogenesis. Despite several studies, the mol. nature of endogenous α-SYN especially in human brain samples is still not well understood due to the lack of reliable methods and the limited amount of biospecimens. Here, we introduce α-SYN single-mol. pull-down (α-SYN SiMPull) assay combined with in vivo protein crosslinking to count individual α-SYN protein and assess its native oligomerization states from biol. samples including human postmortem brains. This powerful single-mol. assay can be highly useful in diagnostic applications using various specimens for neurodegenerative diseases including Alzheimer’s disease and Parkinson’s disease. The experimental process involved the reaction of Bis(2,5-dioxopyrrolidin-1-yl) glutarate(cas: 79642-50-5).Quality Control of Bis(2,5-dioxopyrrolidin-1-yl) glutarate

The Article related to single mol pull down assay alpha synuclein brain human, Biochemical Methods: Immunological and other aspects.Quality Control of Bis(2,5-dioxopyrrolidin-1-yl) glutarate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Beneke, Sascha published an article in 2015, the title of the article was Improving Chromatin Immunoprecipitation (ChIP) by Suppression of Method-Induced DNA-Damage Signaling.Category: esters-buliding-blocks And the article contains the following content:

Genomic DNA is always associated with proteins that modulate the accessibility of the genetic information. This chromatin is the essential structure in which all nuclear activity from regulation to replication, transcription, and repair takes place. This dynamic structure can be most efficiently analyzed by using the method of chromatin immunoprecipitation (ChIP), where application of cell-permeable cross-linkers to living cells induces covalent bridging between proteins and adjacent DNA in the nucleus. After fragmentation of the DNA, the complexed proteins are isolated by binding to specific antibodies. The attached DNA is isolated and can be analyzed. This method has been improved multiple times and adjusted to different exptl. needs. This chapter describes a further advance based on the observation that the current standard method itself induces alterations in the chromatin. The experimental process involved the reaction of Bis(2,5-dioxopyrrolidin-1-yl) glutarate(cas: 79642-50-5).Category: esters-buliding-blocks

The Article related to chromatin immunoprecipitation dna damage signaling, Biochemical Methods: Immunological and other aspects.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On January 31, 2020, Ramos, Sara; Homem, Vera; Santos, Lucia published an article.COA of Formula: C24H27NO2 The title of the article was Analytical methodology to screen UV-filters and synthetic musk compounds in market tomatoes. And the article contained the following:

A Quick, Easy, Cheap, Effective, Rugged and Safe (QuEChERS) methodol. followed by gas chromatog.-tandem mass spectrometry (GC-MS/MS) anal. was developed to extract thirteen synthetic musk compounds (SMCs: cashmeran, celestolide, phantolide, traseolide, galaxolide, tonalide, musk ambrette, musk xylene, musk ketone, musk tibetene, musk moskene, ethylene brassylate and exaltolide) and six UV-filters (UVFs: 2-ethylhexyl 4-dimethylaminobenzoate, 3-(4′-methylbenzylidene) camphor, 2-ethylhexyl 4-methoxycinnamate, 2-ethylhexyl 2-cyano-3,3-diphenylacrylate, benzophenone and drometrizole trisiloxane) from tomatoes. The proposed methodol. was optimized: 2 g of freeze-dried tomato was extracted with 4 mL of water and 10 mL of Et acetate, adding 6 g of MgSO4 and 1.5 g of NaCl, then a dispersive solid-phase extraction was performed using 3 g of MgSO4, 300 mg of primary-secondary amino adsorbent (PSA) and 300 mg of octadecyl-silica (C18). Validation delivered recoveries between 81 (celestolide) and 119% (musk tibetene), with relative standard deviations <10%. The instrumental limit of detection varied from 0.02 (2-ethylhexyl 4-methoxycinnamate) to 3.00 pg (exaltolide and musk xylene). Regarding the method quantification limits, it ranged between 0.4 (celestolide) and 47.9 ng g-1 dw (exaltolide). The method was applied to different varieties of tomatoes (Solanum lycopersicum), revealing UVFs and SMCs between 1 and 210 ng g-1 dw. Higher concentrations were found for benzophenone (29-210 ng g-1 dw) and galaxolide (9-53 ng g-1 dw). The risk associated to the ingestion of contaminated tomatoes has also been estimated, showing that a potential health risk is unlikely. The experimental process involved the reaction of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate(cas: 6197-30-4).COA of Formula: C24H27NO2

The Article related to analytical methodol uv filter synthetic musk compound market tomatoes, daily intake, gc-ms/ms, quechers, synthetic musk compounds, tomatoes, uv-filters, Food and Feed Chemistry: Analysis and other aspects.COA of Formula: C24H27NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Nakamura, Rikako; Sumida, Yuto; Ohmiya, Hirohisa published an article in 2022, the title of the article was Direct Photoexcitable Iodomethylborate Enabling Cyclopropanation of Reactive Alkenes.COA of Formula: C18H17NO4 And the article contains the following content:

A radical-mediated cyclopropanation tool for reactive alkenes, including dehydroamino acids (DHAAs), e.g., benzyl 2-[bis(tert-butoxycarbonyl)amino]acrylate, has been developed based on directly photoexcitable borate generating an iodomethyl radical under visible light irradiation The borate at the excited state serves as a strong single electron reductant. Therefore, this photoexcitable borate offers a simple protocol for cyclopropanation of DHAAs to forge medicinally important cyclopropane amino acids, e.g., I. The experimental process involved the reaction of Benzyl 2-(((benzyloxy)carbonyl)amino)acrylate(cas: 59524-07-1).COA of Formula: C18H17NO4

The Article related to cyclopropane amino acid preparation photoexcitation, alkene iodomethylborate cyclopropanation, Alicyclic Compounds: Cyclopropanes and other aspects.COA of Formula: C18H17NO4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Natrajan, Anand; Sharpe, David; Wen, David published an article in 2012, the title of the article was Zwitterionic reagents for labeling, cross-linking and improving the performance of chemiluminescent immunoassays.COA of Formula: C13H14N2O8 And the article contains the following content:

Improving reagent performance in immunoassays both to enhance assay sensitivity and to minimize interference are ongoing challenges in clin. diagnostics. The authors describe herein the syntheses of a new class of hydrophilic reagents containing sulfobetaine zwitterions and their applications. These zwitterionic reagents are potentially useful for improving the properties of immunoassay reagents. The authors demonstrate for the first time that zwitterion labeling is a general and viable strategy for reducing the nonspecific binding of proteins to microparticles and, to improve the aqueous solubility of hydrophobic peptides. The authors also describe the synthesis of zwitterionic crosslinking reagents and demonstrate their utility for peptide conjugation. In automated, chemiluminescent immunoassays, improved assay performance was observed for a hydrophobic, small analyte (theophylline) using an acridinium ester conjugate with a zwitterionic sulfobetaine linker compared to a hexa(ethylene)glycol linker. Sandwich assay performance for a large analyte (TSH) was similar for the two acridinium ester labels. These results indicate that zwitterions are complementary to poly(ethylene)glycol in improving the aqueous solubility and reducing the nonspecific binding of chemiluminescent acridinium ester conjugates. The experimental process involved the reaction of Bis(2,5-dioxopyrrolidin-1-yl) glutarate(cas: 79642-50-5).COA of Formula: C13H14N2O8

The Article related to zwitterionic reagent labeling crosslinking performance chemiluminescent immunoassay, Biochemical Methods: Immunological and other aspects.COA of Formula: C13H14N2O8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On June 14, 2012, Richards, David N.; Zemlyanov, Dmitry Y.; Ivanisevic, Albena published an article.Electric Literature of 79642-50-5 The title of the article was Kelvin Probe Force Microscopy Analysis of the Covalent Functionalization and DNA Modification of Gallium Phosphide Nanorods. And the article contained the following:

The growth, covalent functionalization, and subsequent DNA modification of Ga phosphide (GaP) nanorods is presented. Anal. of the nanorods by SEM, TEM, and XRD revealed important information regarding their phys. properties such as the presence of twinning defects. The nanorods were deposited onto glass substrates for further functionalization and biomol. immobilization. Plasma cleaning was employed to remove the surfactant present on the nanorods’ surfaces. Kelvin probe force microscopy (KPFM) was used to analyze the extent of plasma cleaning and how it affected the functionalization that employed thiol chem. KFPM anal. of the subsequent modification of functionalized nanorods with single-stranded DNA (ssDNA) revealed that immobilization was dependent on the amount of plasma cleaning to which the nanorods had been exposed. Nanorods were then exposed to the cDNA strand and KPFM was again used to detect successful hybridization. The experimental process involved the reaction of Bis(2,5-dioxopyrrolidin-1-yl) glutarate(cas: 79642-50-5).Electric Literature of 79642-50-5

The Article related to kelvin probe microscopy dna modification gallium phosphide nanorod, Surface Chemistry and Colloids: Other and other aspects.Electric Literature of 79642-50-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On December 31, 2019, Sachs, Parysatis; Ding, Dong; Bergmaier, Philipp; Lamp, Boris; Schlagheck, Christina; Finkernagel, Florian; Nist, Andrea; Stiewe, Thorsten; Mermoud, Jacqueline E. published an article.Recommanded Product: Bis(2,5-dioxopyrrolidin-1-yl) glutarate The title of the article was SMARCAD1 ATPase activity is required to silence endogenous retroviruses in embryonic stem cells. And the article contained the following:

Endogenous retroviruses (ERVs) can confer benefits to their host but present a threat to genome integrity if not regulated correctly. Here we identify the SWI/SNF-like remodeler SMARCAD1 as a key factor in the control of ERVs in embryonic stem cells. SMARCAD1 is enriched at ERV subfamilies class I and II, particularly at active intracisternal A-type particles (IAPs), where it preserves repressive histone methylation marks. Depletion of SMARCAD1 results in de-repression of IAPs and adjacent genes. Recruitment of SMARCAD1 to ERVs is dependent on KAP1, a central component of the silencing machinery. SMARCAD1 and KAP1 occupancy at ERVs is co-dependent and requires the ATPase function of SMARCAD1. Our findings uncover a role for the enzymic activity of SMARCAD1 in cooperating with KAP1 to silence ERVs. This reveals ATP-dependent chromatin remodeling as an integral step in retrotransposon regulation in stem cells and advances our understanding of the mechanisms driving heterochromatin establishment. The experimental process involved the reaction of Bis(2,5-dioxopyrrolidin-1-yl) glutarate(cas: 79642-50-5).Recommanded Product: Bis(2,5-dioxopyrrolidin-1-yl) glutarate

The Article related to retrovirus embryonic stem cell smarcad1, Biochemical Genetics: Genomic Processes and other aspects.Recommanded Product: Bis(2,5-dioxopyrrolidin-1-yl) glutarate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On January 1, 2020, Benjatikul, Kitkanya; Mahamongkol, Hansa; Wongtrakul, Paveena published an article.Reference of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate The title of the article was Sunscreen properties of marl. And the article contained the following:

The physicochem. and sunscreen properties of marl as a function of particle size were investigated. The research findings established that the marl under investigation consisted of more than 95% calcium carbonate (CaCO3). The particles of marl inspected under a scanning electron microscope were calcite, which is the stable polymorph of CaCO3, with a rhombohedral structure. The particle size classification by the sieving method showed that grinding using a ball mill could downsize the marl particles by 2 to 3 times, reaching below 15μm on average Marl particles showed a tendency to reflect UV A (UVA) rays rather than UVB rays and a possibility to steadily absorb both UVAII and UVAI. Finer particles obtained after a longer grinding process demonstrated higher efficacy regarding UV reflection and absorption properties. The 3 weight% marl displayed a sun protection factor (SPF) value of 1 to 2. However, marl demonstrated a good ability to protect against radiation over a broad spectrum range with a critical wavelength above 370 nm. The addition of marl in the formulation containing avobenzone and octinoxate had a pos. synergistic effect because the marl was able to increase the UV absorbance efficacy (based on the area under the curve (AUC) value) and SPF value of the cream. Furthermore, it was also discovered that the added marl powder could slow the decrease in UV protection efficacy of the products in terms of the AUC calculated from the absorbance profile after exposure to simulated UV rays with an amplitude range of 10 J/cm2 to 40 J/cm2 for 30 min, which was similar to the results obtained from octocrylene and bemotrizinol. The experimental process involved the reaction of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate(cas: 6197-30-4).Reference of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate

The Article related to marl particle size sun protection factor uv irradiation, spf, absorption, calcium carbonate, marl, photostability, reflection, sun protection properties, Radiation Biochemistry: Effects In Humans and other aspects.Reference of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics