Tag: 300-400

On March 31, 2022, Downs, C. A.; Bishop, Elizabeth; Diaz-Cruz, M. Silvia; Haghshenas, S. Abbas; Stien, Didier; Rodrigues, Alice M. S.; Woodley, Cheryl M.; Sunyer-Caldu, Adria; Doust, Shadan Nasseri; Espero, William; Ward, Gene; Farhangmehr, Aref; Tabatabaee Samimi, S. Maryam; Risk, Michael J.; Lebaron, Philippe; DiNardo, Joseph C. published an article.Application In Synthesis of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate The title of the article was Oxybenzone contamination from sunscreen pollution and its ecological threat to Hanauma Bay, Oahu, Hawaii, U.S.A.. And the article contained the following:

Hanauma Bay is a 101-acre bay created by the partial collapse of a volcanic cone and once supported a vibrant coral reef system. It is the most popular swimming area in the Hawaiian Islands and has been reported to have averaged between 2.8 and 3.5 million visitors a year between the 1980s and the 2010s, with visitors averaging between 3000-4000 a day and peaking around 10,000-13,000 per day. Concentrations of oxybenzone and other common UV filters were measured in subsurface water samples and in sands from the beach-shower areas in Hanauma Bay. Results demonstrate that beach showers also can be a source of sunscreen environmental contamination. Hydrodynamic modeling indicates that oxybenzone contamination within Hanauma Bay’s waters could be retained between 14 and 50 h from a single release event period. Focusing on only oxybenzone, two different Hazard and Risk Assessment analyses were conducted to determine the danger of oxybenzone to Hanauma Bay’s coral reef system. Results indicate that oxybenzone contamination poses a significant threat to the wildlife of Hanauma Bay. To recover Hanauma Bay’s natural resources to a healthy condition and to satisfactorily conserve its coral reef and sea grass habitats, effective tourism management policies need to be implemented that mitigate the threat of sunscreen pollution. The experimental process involved the reaction of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate(cas: 6197-30-4).Application In Synthesis of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate

The Article related to oxybenzone contamination sunscreen pollution ecol threat hanauma bay, coral, hanauma bay, hydrodynamic modelling, oxybenzone, risk assessment, sunscreen, Water: Water Pollution and other aspects.Application In Synthesis of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On August 1, 2022, Cadena-Aizaga, M. Isabel; Montesdeoca-Esponda, Sarah; Pino, Angelo Santana-Del; Sosa-Ferrera, Zoraida; Santana-Rodriguez, Jose Juan published an article.Synthetic Route of 6197-30-4 The title of the article was Assessment of anthropogenic pollution by UV filters using macrophytes as bioindicators. And the article contained the following:

Marine environment pollution has increased in recent decades as a result of anthropogenic activities. Macrophytes can assimilate the compounds dissolved in the water and respond to changes in surround conditions, for that, they can be used as bioindicators of pollution in aquatic environments. Currently organic UV filters have shown ever-increasing in pollution levels in marine ecosystems. The anthropogenic pollution produced by eight organic UV filters in coastal macrophytes was studied. A microwave-assisted extraction (MAE), followed by ultrahigh-performance liquid chromatog. with tandem mass spectrometry (UHPLC-MS/MS) was applied to 76 macrophyte (seaweeds and seagrass) samples from three different beaches on the Gran Canaria Island (Spain), collected for 6 mo. All studied UV filters were found with different detection frequencies from 16% to 100% in macrophyte samples. Octocrylene (OC) was detected in all the analyzed samples throughout the sampling period. The highest concentration, 19,369 ng·g-1 dry weight (dw), was for this compound in the seagrass Cymodocea nodosa. The bioconcentration ratio was determined for several seaweed groups (red, brown, green). Different bioconcentration grades were obtained. Those above 1000 indicated significant accumulation, which increases the possibility of chronic effects on seaweed and at upper tropic levels. The experimental process involved the reaction of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate(cas: 6197-30-4).Synthetic Route of 6197-30-4

The Article related to macrophyte bioindicator uv filter anthropogenic pollution, anthropogenic contamination, macrophytes, microwave-assisted extraction, organic uv filters, Water: Water Pollution and other aspects.Synthetic Route of 6197-30-4

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On November 15, 2021, Guo, Qiaorong; Wei, Dongbin; Wang, Feipeng; Chen, Miao; Du, Yuguo published an article.Formula: C24H27NO2 The title of the article was A novel risk score-based prioritization method for pollutants in reclaimed water. And the article contained the following:

Wastewater reclamation and reuse is a sustainable solution for alleviating the scarcity of water resources. However, the potential risks resulting from the residual pollutants in reclaimed water are of concern. Identifying of priority pollutants would be a practical approach for the management and scientific evaluation of risks associated with reclaimed water reuse. In this study, a novel risk score-based method is proposed for prioritizing residual pollutants in reclaimed water. First, target the specific applications and possible scenarios of reclaimed water as well as recognize the potential receptors and exposure pathways. Second, determine exposure and effect parameters, and assign values to every parameter. Third, calculate the total exposure score and effect score for each pollutant using a weighted method, then calculate the risk score by multiplying total exposure score and effect score, and rank all pollutants based on their risk scores from high to low. Fourth, recommend a priority pollutants list for reclaimed water reuse. To demonstrate the procedure and validate the method, a case study on groundwater recharge with reclaimed water was conducted. In the case study, EE2 and E2, which have also been listed in other recent water quality standards, were identified as priority pollutants. The case study illustrated sufficient reliability, great discrimination and feasibility of the method. The five exposure parameters and seven effect parameters in this method can objectively evaluate the potential risk of pollutants and identify priority pollutants for the specific application of reclaimed water. This application-oriented and risk-based prioritization method is easy to understand and simple to operate in practice. This study fills existing gaps by proffering a novel prioritization method to identify priority pollutants in reclaimed water for an accurate evaluation and safety management of recycled wastewater. The experimental process involved the reaction of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate(cas: 6197-30-4).Formula: C24H27NO2

The Article related to prioritization method bioaccumulation reclaimed water, adverse effect, exposure, priority pollutants, risk score, wastewater reclamation, Water: Water Pollution and other aspects.Formula: C24H27NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On June 15, 2022, Wang, Wenting; Lee, In-Seok; Oh, Jeong-Eun published an article.Recommanded Product: 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate The title of the article was Specific-accumulation and trophic transfer of UV filters and stabilizers in marine food web. And the article contained the following:

The occurrence and distribution of benzotriazole UV stabilizers (BUVs) and UV filters in marine environments (sediment and seawater) and 20 biota species in the South Korea were investigated to assess their transfer through the marine food web. The total concentrations in the seawater samples were 4.73-8.60 ng/L for BUVs and 1.20-4.88 ng/L for UV filters; while, the total concentrations in the sediment samples were 0.581-6.62 ng/g dw for BUVs and 1.05-6.79 ng/g dw for UV filters, resp. The total concentrations of BUVs and UV filters were a little higher in benthic invertebrates (BUVs: 131 ng/g lipid weight [lw], UV filters: 41.7 ng/g lw) than fish (BUVs: 99.2 ng/g lw, UV filters: 28.0 ng/g lw) but there were no statistical differences (Mann-Whitney U test, p > 0.05). UV-326 was dominant (fish: 37.9%, benthic invertebrate: 48.7%) of the total BUVs. While, benzophenone-3 (fish: 34.1%, benthic invertebrate: 40.8%) and ethylhexyl methoxy cinnamate (fish: 41.0%, benthic invertebrate: 37.8%) were the dominant UV filters. The bioaccumulation factor and trophic magnification factor indicated that UV-326 can both bioaccumulate and biomagnify (bioaccumulation factor >5000 and biota-sediment accumulation and trophic magnification factors >1). Several other BUVs were found to be able to either bioaccumulate (UV-320, UV-P, UV-329, and UV-234) or biomagnify (UV-327 and UV-928). Most of the analyzed UV filters were found not to be likely to bioaccumulate. The experimental process involved the reaction of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate(cas: 6197-30-4).Recommanded Product: 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate

The Article related to marine food web trophic transfer filter stabilizer, benzotriazole uv stabilizer, biomagnification, edi, marine environment, uv filter, Water: Water Pollution and other aspects.Recommanded Product: 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On April 21, 2016, Lin, Wenbin; He, Chunbai; Lu, Kuangda published a patent.Recommanded Product: 1312703-30-2 The title of the patent was Nanoparticles for photodynamic therapy, x-ray induced photodynamic therapy, radiotherapy, chemotherapy, immunotherapy, and any combination thereof. And the patent contained the following:

Metal-organic frameworks (MOFs) comprising photosensitizers are described. The MOFs can also include moieties capable of absorbing X- rays and/or scintillation. Optionally, the photosensitizer or a derivative thereof can form a bridging ligand of the MOF. Further optionally, the MOF can comprise inorganic nanoparticles in the cavities or channels of the MOF or can be used in combination with an inorganic nanoparticle. Also described are methods of using MOFs and/or inorganic nanoparticles in photodynamic therapy or in X-ray induced photodynamic therapy, either with or without the co-administration of one or more immunotherapeutic agent and/or one or more chemotherapeutic agent. The experimental process involved the reaction of Dimethyl 2′-amino-[1,1′:4′,1”-terphenyl]-4,4”-dicarboxylate(cas: 1312703-30-2).Recommanded Product: 1312703-30-2

The Article related to nanoparticle photodynamic therapy antitumor tumor radiotherapy chemotherapy immunotherapy, Pharmaceuticals: Other and other aspects.Recommanded Product: 1312703-30-2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Rasmussen, Kasper D.; Helin, Kristian published an article in 2021, the title of the article was ChIP-Sequencing of TET ProteinsTET proteins.Computed Properties of 79642-50-5 And the article contains the following content:

A review. TET proteins are methylcytosine dioxygenases that interact directly with chromatin to shape the DNA methylation landscape. To increase the understanding of TET protein function in a specific cellular context, it is important to be able to map the interactions between TET proteins and DNA. This ChIP-seq protocol details our procedure to analyze TET2 bound DNA in disuccinimidyl glutarate (DSG) and formaldehyde-crosslinked chromatin but can also be adapted to study other TET enzymes. The experimental process involved the reaction of Bis(2,5-dioxopyrrolidin-1-yl) glutarate(cas: 79642-50-5).Computed Properties of 79642-50-5

The Article related to review sequencing protein disuccinimidyl glutarate formaldehyde, chip-seq, dna methylation, dsg, tet1, tet2, tet3, Biochemical Methods: Reviews and other aspects.Computed Properties of 79642-50-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On July 31, 2022, Yang, Yang; Ako-Adounvo, Ann-Marie; Wang, Jiang; Coelho, Sergio G.; Adah, Steven A.; Matta, Murali K.; Strauss, David; Michele, Theresa M.; Wang, Jian; Faustino, Patrick J.; O’Connor, Thomas; Ashraf, Muhammad published an article.Formula: C24H27NO2 The title of the article was In Vitro Testing of Sunscreens for Dermal Absorption: Method Comparison and Rank Order Correlation with In Vivo Absorption. And the article contained the following:

Evaluating the dermal absorption of sunscreen UV filters requires the development of a bio-predictable in vitro permeation test (IVPT). This work describes the comparison of two IVPT methods and rank order correlations of in vitro absorption (skin permeation and retention) with the in vivo absorption (AUC and skin retention) of sunscreens. The IVPT was compared regarding the following elements: (1) application of a single finite dose vs. an infinite dose and (2) the use of heat-separated human epidermis vs. dermatomed skin models. The IVPT was used to evaluate dermal absorption of six UV filters (avobenzone, homosalate, octinoxate, octisalate, octocrylene, and oxybenzone) in com. sunscreens. Both the in vivo and in vitro permeation studies demonstrated that all UV filters were absorbed following a single-dose application. Sunscreens were rank ordered by the amount of the UV filters absorbed. Data obtained from the IVPT method using a single finite dose and heat-separated human epidermis was found to correlate with the clin. data. Rank orders of the cumulative in vitro skin permeation and the in vivo AUC were found comparable for oxybenzone, homosalate, octisalate, and octinoxate. Rank orders of the in vitro and in vivo skin retention of oxybenzone and octinoxate were also comparable. Addnl. IVPT parameters may be optimized to enhance the discriminatory power for UV filters with low skin permeation potential (e.g., avobenzone and octocrylene). The experimental process involved the reaction of 2-Ethylhexyl 2-cyano-3,3-diphenylacrylate(cas: 6197-30-4).Formula: C24H27NO2

The Article related to rank order correlation dermal absorption sunscreen method comparison, uv filters, absorption, clinical, skin permeation, sunscreen, Pharmaceuticals: Pharmaceutics and other aspects.Formula: C24H27NO2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On April 13, 2006, Robillard, Marc S.; Gruell, Holger published a patent.Application In Synthesis of tert-Butyl 2-(2-(2-(tosyloxy)ethoxy)ethoxy)acetate The title of the patent was Targeted imaging and/or therapy using the Staudinger ligation. And the patent contained the following:

The use of a selective chem. and bioorthogonal reaction providing a covalent ligation such as the Staudinger ligation (reaction between an azide and a phosphine), in targeted mol. imaging and therapy is presented, more specifically with interesting applications for pre-targeted imaging or therapy. Current pre-targeted imaging is hampered by the fact that it relies solely on natural/biol. targeting constructs (i.e. biotin/streptavidin). Size considerations and limitations associated with their endogenous nature severely limit the number of applications. The present invention describes how the use of an abiotic, bio-orthogonal reaction which forms a stable adduct under physiol. conditions, by way of a small or undetectable bond, can overcome these limitations. As an example of pre-targeted imaging, injection of a targeting probe comprising a somatostatin receptor-binding peptide linked to an azide is followed by a secondary radiolabeled probe linked to a Staudinger phosphine group. Following in vivo Staudinger ligation, the radiolabel enables detection of the presence of somatostatin receptor-pos. tissue such as neuroendocrine tumor. The experimental process involved the reaction of tert-Butyl 2-(2-(2-(tosyloxy)ethoxy)ethoxy)acetate(cas: 882518-89-0).Application In Synthesis of tert-Butyl 2-(2-(2-(tosyloxy)ethoxy)ethoxy)acetate

The Article related to staudinger ligation targeted imaging therapy, azide phosphine reaction targeted contrast agent delivery, Pharmaceuticals: Pharmaceutics and other aspects.Application In Synthesis of tert-Butyl 2-(2-(2-(tosyloxy)ethoxy)ethoxy)acetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

On March 31, 2010, Pillai, R.; Marinelli, E. R.; Fan, H.; Nanjappan, P.; Song, B.; von Wronski, M. A.; Cherkaoui, S.; Tardy, I.; Pochon, S.; Schneider, M.; Nunn, A. D.; Swenson, R. E. published an article.Application In Synthesis of Bis(2,5-dioxopyrrolidin-1-yl) glutarate The title of the article was A Phospholipid-PEG2000 Conjugate of a Vascular Endothelial Growth Factor Receptor 2 (VEGFR2)-Targeting Heterodimer Peptide for Contrast-Enhanced Ultrasound Imaging of Angiogenesis. And the article contained the following:

The transition of a targeted ultrasound contrast agent from animal imaging to testing in clin. studies requires considerable chem. development. The nature of the construct changes from an agent that is chem. attached to microbubbles to one where the targeting group is coupled to a phospholipid, for direct incorporation to the bubble surface. We provide an efficient method to attach a heterodimeric peptide to a pegylated phospholipid and show that the resulting construct retains nanomolar affinity for its target, vascular endothelial growth factor receptor 2 (VEGFR2), for both the human (kinase insert domain-containing receptor – KDR) and the mouse (fetal liver kinase 1 – Flk-1) receptors. The purified phospholipid-PEG-peptide isolated from TFA-based eluents is not stable with respect to hydrolysis of the fatty ester moieties. This leads to the time-dependent formation of the lysophospholipid and the phosphoglycerylamide derived from the degradation of the product. Purification of the product using neutral eluent systems provides a stable product. Methods to prepare the lysophospholipid (hydrolysis product) are also included. Biacore binding data demonstrated the retention of binding of the lipopeptide to the KDR receptor. The phospholipid-PEG2000-peptide is smoothly incorporated into gas-filled microbubbles and provides imaging of angiogenesis in a rat tumor model. The experimental process involved the reaction of Bis(2,5-dioxopyrrolidin-1-yl) glutarate(cas: 79642-50-5).Application In Synthesis of Bis(2,5-dioxopyrrolidin-1-yl) glutarate

The Article related to preparation phospholipid polyethylene glycol conjugate contrast ultrasound imaging angiogenesis, Pharmaceuticals: Pharmaceutics and other aspects.Application In Synthesis of Bis(2,5-dioxopyrrolidin-1-yl) glutarate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Aruna, Kasoju; Munawar, T. Mohammad; Prashanthi, M. V.; Narsu, M. Lakshmi published an article in 2013, the title of the article was Optimisation studies of probe DNA concentration on the surface of silica nanobiosensor.Quality Control of Bis(2,5-dioxopyrrolidin-1-yl) glutarate And the article contains the following content:

Biosensors with immobilized probe that are selective for the identification of toxic compounds at ultra trace levels in industrial products, chem. substances, environmental samples or biol. systems (e.g., Bacteria, virus, or tissue components) for biomedical diagnosis. Nanomaterials such as silica nanoparticles works as sensor when probe hybridized with the target sequence. Due to their large surface area to volume ratio, they can achieve rapid and low cost reactions. They can conjugate with a variety of biomols. (Proteins, enzymes, peptides, and DNA) and used as fluorescence biomarkers to monitor biol. events or identify and detect biol. targets. DNA biosensors based on nucleic acid hybridization were extensively developed because of their specificity, speed, portability, and low cost. The immobilization step is essential to ensure high reactivity, orientation, accessibility, and stability of the surface-confined probe and to avoid nonspecific binding. Various studies, i.e., a synthesis of silica nanoparticles, their surface modification, probe immobilization were carried out during optimization of reaction conditions. In this present work, 3.4% more immobilization of probe DNA onto the silica nanoparticle was observed in the presence of 10% butyltrimethoxysilane solution rather than absence of BMS and the concentration of the DNA probe immobilized on silica nanoparticles was maximum at 1Picomloles/μl was noticed. The experimental process involved the reaction of Bis(2,5-dioxopyrrolidin-1-yl) glutarate(cas: 79642-50-5).Quality Control of Bis(2,5-dioxopyrrolidin-1-yl) glutarate

The Article related to silica nanoparticle dna probe immobilization butyltrimethoxysilane biosensor, Biochemical Methods: Apparatus and other aspects.Quality Control of Bis(2,5-dioxopyrrolidin-1-yl) glutarate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics