Tag: 300-400

Evaporative light scattering detection based reversed-phase ultra-high-performance liquid chromatography method to quantify intermediates and end products of biodiesel production was written by Nakai, Diogo K.;Ribeiro, Jose A. A.;Martins, Pedro A.;Soares, Itania P.;Salum, Thais F. C.;Costa, Patricia P. K. G.. And the article was included in Journal of Chromatography A in 2022.SDS of cas: 31566-31-1 The following contents are mentioned in the article:

A fast method based on reversed-phase ultra-high-performance liquid chromatog. using evaporative light scattering detection (RP-UHPLC-ELSD) was developed for monitoring the intermediates and end products of biodiesel production Gradient elution of water, acetonitrile, and a mixture of acetonitrile:2-propanol:n-hexane was used. With a minimal and easy sample preparation, fatty acid Me esters (FAME), fatty acid Et esters (FAEE), free fatty acids (FFA), monoacylglycerols (MAG), diacylglycerols (DAG), and triacylglycerols (TAG) were successfully separated The developed method was used to monitor an ethylic enzymic transesterification of soybean oil and to characterize the ester content of Me and Et biodiesel. The ester content obtained was compared with the reference method by gas chromatog. and flame ionization detector (GC-FID), with similar results for both Me and Et biodiesel. The presented method is a simple and fast alternative, a 17 min run, to monitor the transesterification process, simultaneously quantifying all the analytes produced in the reaction: biodiesel and its intermediates. Limits of detection (LOD, between 29 and 307 ng) and quantification (LOQ, between 48 and 614 ng), linearity (R2>0.99), precision (between 0.30 and 6.58%), and accuracy (between 81.6 and 119.9%) were determined for the twenty-one compounds This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1SDS of cas: 31566-31-1).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.SDS of cas: 31566-31-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Nocardia stercoris sp. nov., a novel actinomycete isolated from the cow dung was written by Zhao, Junwei;Han, Xiaoyang;Hu, Hailong;Ling, Ling;Zhang, Xue;Guo, Xiaowei;Wang, Xiangjing;Xiang, Wensheng. And the article was included in International Journal of Systematic and Evolutionary Microbiology in 2020.Synthetic Route of C20H40O2 The following contents are mentioned in the article:

A novel actinobacterial strain, designated NEAU-LL90T, was isolated from cow dung collected from Shangzhi, Heilongjiang Province, north-east PR China and characterized by using a polyphasic approach. Morphol. and chemotaxonomic characteristics were consistent with those members of the genus Nocardia. The polar lipids consisted of diphosphatidylglycerol, phosphatidylethanolamine, phosphatidylinositol and phosphatidylinositol mannoside. The predominant menaquinone detected was MK-8(H4, ω-cycl). Major fatty acids (>10%) were identified as C_16:0, C_18:1ω9c, C_18:0 and 10-Me C_19:0. Mycolic acids were present. The results of 16S rRNA gene sequence anal. showed that strain NEAU-LL90T belongs to the genus Nocardia with high sequence similarity to Nocardia niigatensis JCM11894T (98.1%), similarities to other type strains of species of the genus Nocardia were found to be lower than 98.0%. Furthermore, a combination of DNA-DNA hybridization results and some phenotypic characteristics demonstrated that strain NEAU-LL90T could be distinguished from its closest relative. Therefore, it is proposed that strain NEAU-LL90T represents a novel species of the genus Nocardia, for which the name Nocardia stercoris sp. nov. is proposed. The type strain is NEAU-LL90T (= CGMCC 4.7500T = JCM 32663T). This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Synthetic Route of C20H40O2).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Synthetic Route of C20H40O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ultrasonic-assisted phosphate curing: a novel approach to improve curing rate and chicken meat quality was written by Tong, Huiquan;Cao, Changwei;Du, Yanli;Liu, Yong;Huang, Wei. And the article was included in International Journal of Food Science and Technology in 2022.Quality Control of Methyl nonadecanoate The following contents are mentioned in the article:

The effects of ultrasound-assisted phosphate curing (UPC), phosphate curing (PC), and deionised water curing (DC) on the quality of chicken breast meat were investigated. The anal. of tissue sections, low-field NMR (LF-NMR), and headspace solid-phase microextraction gas-phase mass spectrometry (HS-SPME-GC-MS) of water distribution, myofibrillary structure, and volatile components of the meat samples were performed to reveal the mechanism. Also, the curing rate, water holding capacity (WHC), and shear force of meat were assessed. The results revealed that ultrasonic-assisted salting improved the meat salting rate, WHC, and tenderness by mech. destroying the muscle fiber structure, increasing the space between the muscle fiber bundles, promoting water migration and uniform distribution, and reducing water freedom in the treated samples. In addition, HS-SPME-GC-MS anal. revealed that PC significantly reduced the content of volatile flavor components in the chicken breast meat compared with DC (P < 0.05); however, the combination treatment with PC and ultrasonic curing could reconstruct the flavor loss caused by phosphate. Thus, our cumulative results suggest that the ultrasonic technol. may effectively assist the processing technol. in improving the quality of meat and reconstructing the flavor loss in meat products. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Quality Control of Methyl nonadecanoate).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Quality Control of Methyl nonadecanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effects of Glycosylation and D-Amino Acid Substitution on the Antitumor and Antibacterial Activities of Bee Venom Peptide HYL was written by Wu, Ming-hao;Ai, Su;Chen, Qing;Chen, Xiang-yan;Li, Hong-jin;Li, Yu-lei;Zhao, Xia. And the article was included in Bioconjugate Chemistry in 2020.Product Details of 604-69-3 The following contents are mentioned in the article:

Glycosylation is a promising strategy for modulating the physicochem. properties of peptides. However, the influence of glycosylation on the biol. activities of peptides remains unknown. Here, we chose the bee venom peptide HYL as a model peptide and 12 different monosaccharides as model sugars to study the effects of glycosylation site, number, and monosaccharide structure on the biochem. properties, activities, and cellular selectivities of HYL derivatives Some analogs of HYL showed improvement not only in cell selectivity and proteolytic stability but also in antitumor and antimicrobial activity. Moreover, we found that the helicity of glycopeptides can affect its antitumor activity and proteolytic stability, and the α-linked D-monosaccharides can effectively improve the antitumor activity of HYL. Therefore, it is possible to design peptides with improved properties by varying the number, structure, and position of monosaccharides. What’s more, the glycopeptides HYL-31 and HYL-33 show a promising prospect for antitumor and antimicrobial drugs development, resp. In addition, we found that the D-lysine substitution strategy can significantly improve the proteolytic stability of HYL. Our new approach provides a reference or guidance for the research of novel antitumor and antimicrobial peptide drugs. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Product Details of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Product Details of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Solubility determination, model evaluation, Hansen solubility parameter and thermodynamic properties of benorilate in six pure solvents and two binary solvent mixtures was written by Sha, Jiao;Ma, Teng;Huang, Zibo;Hu, Xiaoran;Zhang, Ruke;Cao, Zidan;Wan, Yameng;Sun, Renren;He, Haixia;Jiang, Gaoliang;Li, Yu;Li, Tao;Ren, Baozeng. And the article was included in Journal of Chemical Thermodynamics in 2021.Safety of 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

The equilibrium solubility and thermodn. properties of benorilate in six pure solvents (Me acetate, Pr acetate, Bu acetate, n-pentyl acetate, DMAC and DMSO) and two binary solvents (DMAC + n-pentyl acetate, DMSO + n-pentyl acetate) were reported. Solubility determinations were performed through the laser monitoring method at T = (278.15-323.15) K and p = 0.1 MPa, except DMSO at (293.15-323.15) K. The measurement results illustrated that the solubility of benorilate in all the six mono-solvents and two binary solvents shows a pos. relation with temperature variation. And with the mass fraction of pos. solvents (DMAC, DMSO) in the binary mixed solvents increasing, the solubility of benorilate also rises. And then, the Hansen solubility parameter (HSP) of benorilate as well as solvents selected were summarized to analyze the probabilities of miscibility between solute and solvents. The results indicate that the HSP could explain the solubility trend well, and the miscibility of benorilate with selected solvents is caused by a combination of factors. In addition, all recorded solubility of benorilate in pure solvents were regressed by λh, modified Apleblat, Two-Suffix Margules, NRTL and UNIQUAC models, while solubility of benorilate in two binary solvents were regressed by λh, modified Apleblat, Three-Suffix Margules, NRTL and UNIQUAC models. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Safety of 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Safety of 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents was written by Huang, Jian;Yuan, Yafei;Zhao, Na;Pu, Debing;Tang, Qingxuan;Zhang, Shuo;Luo, Shuchen;Yang, Xikang;Wang, Nan;Xiao, Yu;Zhang, Tuan;Liu, Zhuoyi;Sakata-Kato, Tomoyo;Jiang, Xin;Kato, Nobutaka;Yan, Nieng;Yin, Hang. And the article was included in Proceedings of the National Academy of Sciences of the United States of America in 2021.Application of 604-69-3 The following contents are mentioned in the article:

Artemisinin-resistant malaria parasites have emerged and have been spreading, posing a significant public health challenge. Antimalarial drugs with novel mechanisms of action are therefore urgently needed. In this report, we exploit a ‘selective starvation’ strategy by inhibiting Plasmodium falciparum hexose transporter 1 (PfHT1), the sole hexose transporter in P. falciparum, over human glucose transporter 1 (hGLUT1), providing an alternative approach to fight against multidrug-resistant malaria parasites. The crystal structure of hGLUT3, which shares 80% sequence similarity with hGLUT1, was resolved in complex with C3361, a moderate PfHT1-specific inhibitor, at 2.3-Å resolution Structural comparison between the present hGLUT3-C3361 and our previously reported PfHT1-C3361 confirmed the unique inhibitor binding-induced pocket in PfHT1. We then designed small mols. to simultaneously block the orthosteric and allosteric pockets of PfHT1. Through extensive structure-activity relationship studies, the TH-PF series was identified to selectively inhibit PfHT1 over hGLUT1 and potent against multiple strains of the blood-stage P. falciparum. Our findings shed light on the next-generation chemotherapeutics with a paradigm-shifting structure-based design strategy to simultaneously target the orthosteric and allosteric sites of a transporter. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Application of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Application of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Comprehensive evaluation of saturated monoglycerides for the forming of oleogels was written by Li, Jiaxi;Guo, Ruihua;Bi, Yanlan;Zhang, Hong;Xu, Xuebing. And the article was included in LWT–Food Science and Technology in 2021.Recommanded Product: 31566-31-1 The following contents are mentioned in the article:

To investigate the effect of monoglyceride (MGs) acyl chain length and compounding of MGs on the oleogel properties and stability, 3 different pure MGs and 7 mixtures with different glycerol monostearate (MS): glycerol monobehenate (MB) ratios were studied with high oleic sunflower oil (HOSO) as the liquid oil. The oleogel properties were characterized in terms of structuring potential including oil binding capacity (OBC), hardness and rheol. behavior, and the microstructural features associated with these properties determined by differential scanning calorimetry (DSC), solid fat content (SFC), X-ray diffractometry (XRD) and polarized light microscopy (PLM). Changes in oleogel properties (OBC and hardness) and the microstructure during 30 days of storage were also evaluated. Different chain lengths and ratios of MS:MB led to different crystallization rates, polymorphic transitions and aggregation rates, so as to form different crystalline networks and stabilities. In general, the MB oleogel exhibited the highest properties and stability. An increase in OBC in the order of glycerol monolaurate (ML) < MS < MB was observed for pure MG oleogels. The oleogels with mixed MGs outperformed the mech. properties of the single ones. The best oleogel properties and stabilities were obtained for the oleogel with the MS:MB ratio as 2:8. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Recommanded Product: 31566-31-1).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Recommanded Product: 31566-31-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Nanostuctured lipid based drug delivery system of lopinavir- optimization and evaluation was written by Sawale, Sunil Rambhau;Shete, R. V.;Bhagat, Vishwas C.;Deshmukh, Madhuri T.. And the article was included in World Journal of Pharmaceutical Research in 2022.HPLC of Formula: 31566-31-1 The following contents are mentioned in the article:

By using the high-shear homogenization method Nanostructured lipid carriers (NLCs) loaded with lopinavir (LOP) were prepared The LOPNLCs formulations were freeze-dried using POLOXOMER 188 as a cryoprotectant. A burst release is shown by in vitro release studies in simulated gastric fluid (pH 1.2) and simulated intestinal fluid (pH 6.8). The optimized freeze-dried formulation (LOP-NLC) had a particle size (PS), zeta potential (ZP) and % entrapment efficiency (%EE) of 159.5 _ 3.75 nm, 0.413 _ 0.017, -46 mV and 97.77 _ 4.46%, resp. A spherical shape was observed in the optimized formulation by transmission and scanning electron microscopes. The absence of chem. interaction between the drug and lipids is observed in Differential scanning Calorimetry study. In vitro study is performed using the bulk-equilibrium reverse dialysis technique, to investigate LOP release from optimized LOP-NLC and pure drug suspension in different media. The optimized formulations stored in amber glass container were found to be phys. and chem. stable for three months at room temperature The bioavailability of LOP following oral administration of LOP-NLC in male Wistar rats was found 4.52-fold higher than the LOP-suspension. So the conclusion is:- for improving the oral bioavailability of lopinavir, the nanostructure lipid carriers are potential carriers. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1HPLC of Formula: 31566-31-1).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.HPLC of Formula: 31566-31-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Virtual screening of plant compounds and nonsteroidal anti-inflammatory drugs for inhibition of quorum sensing and biofilm formation in Salmonella was written by Almeida, Felipe Alves de;Vargas, Erika Lorena Giraldo;Carneiro, Deisy Guimaraes;Pinto, Uelinton Manoel;Vanetti, Maria Cristina Dantas. And the article was included in Microbial Pathogenesis in 2018.Computed Properties of C17H15NO5 The following contents are mentioned in the article:

Salmonella belongs to the Enterobacteriaceae family which is widely distributed in the environment due to its adaptive capacity to stress conditions. In addition, Salmonella is able to perform a type of cell-to-cell communication called quorum sensing, which leads to differential gene expression. The quorum sensing system mediated by AI-1, acyl homoserine lactones (AHLs), is incomplete in Salmonella because the luxI homolog gene, which encodes for AI-1 synthase, is missing in the genome. However, a homolog of LuxR, known as SdiA, is present and allows the detection of signaling mols. produced by other species of bacteria, leading to regulation of gene expression, mainly related to virulence and biofilm formation. Thus, in view of the importance of quorum sensing on the physiol. regulation of microorganisms, the aim of the present study was to perform a virtual screening of plant compounds and nonsteroidal anti-inflammatory drugs (NASIDs) for inhibition of quorum sensing by mol. docking and biofilm formation in Salmonella. In general, most plant compounds and all NSAIDs bound in, at least, one of the three modeled structures of SdiA proteins of Salmonella Enteritidis PT4 578. In addition, many tested compounds had higher binding affinities than the AHLs and the furanones which are inducers and inhibitors of quorum sensing, resp. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Computed Properties of C17H15NO5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Computed Properties of C17H15NO5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Short-Chain Mono-Alkyl β-D-Glucoside Crystals-Do They Form a Cubic Crystal Structure? was written by Ogawa, Shigesaburo;Takahashi, Isao. And the article was included in Molecules in 2022.HPLC of Formula: 604-69-3 The following contents are mentioned in the article:

Three-dimensional liquid crystal (LC) phases, cubic LC phases, have been extensively studied as fascinating mol. assembled systems formed by amphiphilic compounds However, similar structures have only been seen in rare instances in lipid crystal states in glycolipid crystal studies. In this study, we prepared short-chain n-alkyl β-D-glucosides (CnG) with an alkyl chain length n ranging from 4 to 6 and investigated their crystal structures. First, DTA (DTA) and thermogravimetric anal. (TG) measurements showed the formation of hydrated crystals for C4G and C5G, resp. Second, the crystal structures of CnG (n = 4, 5, 6) in both anhydrous and hydrated states were examined using a temperature-controlled powder X-ray diffraction (PXRD) measurement. Both hydrate and anhydrous crystals of C4G and C5G with critical packing parameters (CPPs) less than 0.33 formed cubic crystal phases. Bilayer lengths, calculated from the main diffraction peaks in each PXRD profile, depended on crystalline moisture for C5G, but no significant change was confirmed for C4G, indicating that the properties of each hydrophilic layer differ. However, C6G with a CPP of 0.42 formed a crystal structure with a modulated lamellar structure similar to C7G and C8G with similar CPP values. Thus, a glycolipid motif concept with a cubic crystal structure was demonstrated. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3HPLC of Formula: 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.HPLC of Formula: 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics