Tag: 300-400

Instant soups from cowpea varieties using foam-mat drying was written by Falade, Kolawole O.;Adeniyi, Oluwasanmi G.. And the article was included in LWT–Food Science and Technology in 2021.Electric Literature of C21H44O5 The following contents are mentioned in the article:

The effect of glyceryl monostearate (GMS) concentration (50, 100, 150, 200, and 250 mg/kg) on foam d. of cooked paste, and functional and sensory properties of instant soups from four cowpea varieties (Sokoto, Drum, Honey and Mala beans) was evaluated. The foam d. decreased with increased glycerol monostearate (GMS) concentration across the varieties. Foam d. (0.49-1.05 g/mL) of the cooked paste varied with glycerol monostearate concentration and cowpea variety. Swelling capacity (14.0-36.5 g/mL), water absorption (2.5-3.6 g/mL), oil absorption (1.1-1.7 g/mL), loose (0.6-0.8 g/mL) and packed (0.8-1.1 g/mL) bulk densities of the instant cowpea soup powders were significantly affected (p < 0.05) by the GMS concentration and variety. The L* (70.7-94.3), a* (-1.7-1.4), and b* (17.3-21.5) parameters of the foam-mat dried (instant soups) powders were significantly affected by cowpea varieties and GMS concentration Sensory evaluation conducted on the reconstituted powder and freshly made soup were significantly different. Among the reconstituted foam mat dried (instant soups) powders, reconstituted cooked paste from Drum cowpea variety with 50 mg/kg GMS was the most preferred by the panellists (6.8). Foam mat drying of cooked cowpea paste could be reconstituted into acceptable instant soup. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Electric Literature of C21H44O5).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Electric Literature of C21H44O5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Solubility Determination and Model Correlation of Benorilate between T = 278.18 and 318.15 K was written by Wu, Yufang;Ren, Maolin;Zhang, Xiaolu. And the article was included in Journal of Chemical & Engineering Data in 2020.Related Products of 5003-48-5 The following contents are mentioned in the article:

The objective is to study the solubility of benorilate in 12 pure solvents at from 278.15 to 318.15 K by the isothermal saturation method at atm. pressure. The solubility increased monotonically with the rising temperature Moreover, at all evaluated temperatures, the largest solubility value was obtained in N-methyl-2-pyrrolidone, followed by N,N-dimethylformamide > 2-butanone > 1,4-dioxane > acetonitrile > Et acetate > 1-butanol > ethanol > methanol > n-propanol > isopropanol > toluene. The solubility values in the reaction solvent (toluene) varied from 1.3 x 10^-5 to 1.08 x 10^-4 in mole fraction between T = 278.15 and 318.15 K, an increase of 8.31-fold. At all evaluated temperatures, the values in ethanol increased from 1.58 x 10^-4 to 9.07 x 10^-4 in mole fraction, an increase of 5.74-fold. Hence, the precipitation and the crystallization purification of benorilate could be effectively controlled by changing the temperature The obtained solubility data were correlated with the modified Apelblat equation and λh equation. The results of relative average deviations indicated that both the λh equation and the modified Apelblat equation are capable of describing the solubility of benorilate in selected pure solvents. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Related Products of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Related Products of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Formulation and evaluation of Darunavir loaded solid lipid nanoparticles was written by Sandirigiri, Dinesh Kumar;Vijetha, K. Anie. And the article was included in World Journal of Pharmacy and Pharmaceutical Sciences in 2022.Quality Control of Glyceryl monostearate The following contents are mentioned in the article:

Darunavir is an anti-retroviral drug and it is inhibitor of HIV protease with poor water solubility So, the main objective of the study is to improve the solubility and bioavailability of poor water soluble drug Darunavir. The Present study outlines the formulation of the Darunavir loaded solid lipid nanoparticles, Particle size anal., Surface morphol., dissolution studies, drug loading, entrapment efficiency and drug release kinetics along with mechanisms. In general, Solid lipid nanoparticles were prepared by using various methods like homogenization, ultrasonication. The Optimized Solid lipid nanoparticles formed with Darunavir resulted in particle size of 334 nm, Poly dispersity index (0.184), zeta potential (-12.75) which results in stable dispersion. In-vitro drug release studies in 6.8 PH phosphate buffer shown 91.2% drug release at the last time period of 12 h and followed zero order release kinetics. Differential Scanning Calorimetry Studies were performed and found no chem. interactions. Surface morphol. was studied by SEM anal. and found that particles with spherical shape and smooth surface were appeared. Accelerated stability studies which was performed at 25.30 and 400 C temperatures after 3 mo there was no change in the stability of dispersion upon storage conditions. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Quality Control of Glyceryl monostearate).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Quality Control of Glyceryl monostearate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Magnetic graphene based dispersive micro-solid-phase extraction coupled with liquid chromatography-tandem quadrupole mass spectrometry for analysis of nine non-steroidal anti-inflammatory drugs in livestock and poultry meat was written by Dong, Chanchan;Hu, Yanyun;Lu, Yaning;Song, Wei;Han, Fang;Zheng, Ping;Deng, Ning. And the article was included in Sepu in 2016.Product Details of 5003-48-5 The following contents are mentioned in the article:

A novel anal. method was developed for the determination of nine non-steroidal anti-inflammatory drugs (NSAIDs) in meat samples by magnetic graphene nanocomposite (Fe₃O₄-G) based on dispersive micro-solid-phase extraction (μ-SPE) coupled with liquid chromatog.-mass spectrometry detection. Samples were homogenized and extracted with acidified acetonitrile. After defatting with the high speed frozen centrifugation, the sample solutions were defatted with n-hexane followed by μ-SPE. Some important parameters influencing the extraction efficiency including the extraction time, the pH value of sample solution and the elution conditions were optimized. The limits of detection (LODs, S/N = 3) of the nine NSAIDs ranged from 0.2 to 8.2 μg/kg, and the limits of quantification (LOQs, S/N = 10) ranged from 0.5 to 25.4 μg/kg. The average recoveries were 83.3%-104.5% with the relative standard deviations between 1.2% and 6.8% obtained from samples spiked at LOQ, 2LOQ and 10LOQ levels. Compared with Sep-Pak Vac NH₂ and Oasis HLB cartridges, Fe₃O₄-G had excellent purification effect, high loading amounts and good reusability. The results demonstrate that the method provide a novel pretreatment technique for the determination of NSAID residues in meat samples. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Product Details of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Product Details of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Continuous biodiesel production in a helicoidal reactor using ultrasound-assisted transesterification reaction of waste cooking oil was written by Delavari, Armin;Halek, Farah;Amini, Mohammad. And the article was included in Clean Technologies and Environmental Policy in 2015.Formula: C20H40O2 The following contents are mentioned in the article:

Designing of a continuous biodiesel production system from waste cooking oil with ultrasonic homogenizer assistant through transesterification reaction was studied. Through some pre-tests based on cavitation phenomenon to accelerate the transesterification reaction, two types of reactors (batch and continuous) were used. GC-MS results showed the total content of 94.2 % of Me esters derived from different fatty acids formed in a batch reactor using a magnetic stirrer and an elec. heater. These results were then compared to those of two ultrasonic homogenizers with low and high capacities of 400 and 1,500 W, which tested successfully under mild conditions. The results indicated the advantages of using ultrasonic homogenizer. The continuous system consisted of a 1,500 W ultrasonic homogenizer and glass helicoidal reactor with a tube length of 20 m. This set-up was kept submerged in a hot water bath. As a result, the reaction time decreased to 150 s, the methanol/oil molar ratio was 8.6 and the weight % of NaOH/oil was 0.5 %. After separation of undesired contents, the phys. and chem. characteristics of the final product were measured according to ASTM standard methods. Study of performance of the system also showed a significant improvement in yield of the reaction (90 %) compared to prior studies. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Formula: C20H40O2).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Formula: C20H40O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Optimization of oil yield of Phaleria macrocarpa seed using response surface methodology and its fatty acids constituents was written by Azmir, J.;Zaidul, I. S. M.;Rahman, M. M.;Sharif, K. M.;Sahena, F.;Jahurul, M. H. A.;Mohamed, A.. And the article was included in Industrial Crops and Products in 2014.Application In Synthesis of Methyl nonadecanoate The following contents are mentioned in the article:

Phaleria macrocarpa (Mahkota dewa) seed was examined to determine the optimal conditions of oil yield by solvent extraction method using n-hexane as extracting solvent. Response surface methodol. (RSM) was employed to describe explicitly the influence of extraction time, temperature and solvent-to-feed ratio on the yield of oil using central composite design (CCD). The linear, quadratic and interaction terms of the studied variables have significant (P < 0.05) effect on the oil yield. The temperature of 72 °C, extraction time of 8.4 h and solvent-to-feed ratio of 10.9 mL/g were the optimal conditions for seed oil extraction The maximum oil yield was 55.32 g/100 g dry weight under these optimal conditions. Main chem. constituents of oil were determined by Gas chromatog.-mass spectroscopy (GC-MS) and Fourier transform IR spectroscopy (FTIR). Twelve components were identified by GC-MS anal. after formation of fatty acid Me ester (FAME). Total saturated fatty acids were 19.38% whereas monounsaturated fatty acids and polyunsaturated fatty acids were 44.23% and 36.38%, resp. Oleic acid, 18:1 (43.56%) and linoleic acid, 18:2 (36.25%) were the main fatty acid constituents of Mahkota dewa seed oil. The quantity of unsaturated fatty acids was higher than saturated fatty acids in P. macrocarpa seed oil. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Application In Synthesis of Methyl nonadecanoate).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application In Synthesis of Methyl nonadecanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

CuAAC mediated synthesis of cyclen cored glycodendrimers of high sugar tethers at low generation was written by Agrahari, Anand K.;Jaiswal, Manoj K.;Yadav, Mangal S.;Tiwari, Vinod K.. And the article was included in Carbohydrate Research in 2021.SDS of cas: 604-69-3 The following contents are mentioned in the article:

Glycodendrimers are receiving considerable attention to mimic a number of imperative features of cell surface glycoconjugate and acquired excellent relevance to a wide domain of investigations including medicine, pharmaceutics, catalysis, nanotechnol., carbohydrate-protein interaction, and moreover in drug delivery systems. Toward this end, an expeditious, modular, and regioselective triazole-forming CuAAC click approach along with double stage convergent synthetic method was chosen to develop a variety of novel chlorine-containing cyclen cored glycodendrimers of high sugar tethers at low generation of promising therapeutic potential. We developed a novel chlorine-containing hyper-core unit with 12 alkynyl functionality originated from cyclen scaffold which was confirmed by its single crystal X-ray data anal. Further, the modular CuAAC technique was utilized to produce a variety of novel 12-sugar coated (G₀) glycodendrimers with β-Glc-, β-Man-, β-Gal-, β-Lac, along with 36-galactose coated (G₁) glycodendrimer in good-to-high yield. The structures of the developed glycodendrimer architectures have been well elucidated by extensive spectral anal. including NMR (¹H & ¹³CNMR), HRMS, MALDI-TOF MS, UV-Vis, IR, and SEC (Size Exclusion Chromatogram) data. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3SDS of cas: 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.SDS of cas: 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Comparative chemical and biological study of roots and aerial parts of Halocnemum strobilaceum growing wildly in Egypt was written by Abdel Razek, M. M. M.;Moussa, A. Y.;El-Shanawany, M. A.;Singab, A. B.. And the article was included in Journal of Pharmaceutical Sciences and Research in 2019.Safety of Methyl nonadecanoate The following contents are mentioned in the article:

Halocnemum strobilaceum is a terrestrial halophytic plant with reported folk medicinal uses. RAPD-PCR was used to amplify the DNA fragments where 83 amplified DNA fragments result from the RAPD-PCR, and primer P2 was the best sequence dominating them. GC/MS anal. identified the components of both the root and the aerial parts hexane extracts as hexadecanoic acid Me ester (38.88%) and 9-octadecenoic acid (Z)- Me ester (23.25%) in the former and dodecane (9.83%), heptadecane (8.26%) and octadecane (8.2%) in the latter. MTT cell viability assay was carried out on three different human cell lines, MCF-7, Hep-G2 and Caco-2, to evaluate the cytotoxic potential of H. strobilaceum; furthermore, the cup well diffusion and serial dilution methods were utilized to screen for the anti-infective potential. Marked activity was recorded for the aerial part against the MCF-7 cell line after 24h, 48h and 72h, with IC50 values of 227.40, 184.45 and 135.68 μg/mL, resp., and moderate cell killing effect was manifested by the root part with IC50 values of 341.98, 308.77 and 218.99 μg/mL. H. strobilaceum root extract exhibits significant effect against Bacillus subtilis and Staphylococcus aureus, with MIC values of 6.25 and 50 μg/mL resp. H. strobilaceum is a promising candidate for further future biol. studies. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Safety of Methyl nonadecanoate).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Safety of Methyl nonadecanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Analysis of Physicochemical Properties for Drugs of Natural Origin was written by Camp, David;Garavelas, Agatha;Campitelli, Marc. And the article was included in Journal of Natural Products in 2015.Category: esters-buliding-blocks The following contents are mentioned in the article:

The impact of time, therapy area, and route of administration on 13 physicochem. properties calculated for 664 drugs developed from a natural prototype was investigated. The mean values for the majority of properties sampled over five periods from pre-1900 to 2013 were found to change in a statistically significant manner. In contrast, lipophilicity and aromatic ring count remained relatively constant, suggesting that these parameters are the most important for successful prosecution of a natural product drug discovery program if the route of administration is not focused exclusively on oral availability. An examination by therapy area revealed that anti-infective agents had the most differences in physicochem. property profiles compared with other areas, particularly with respect to lipophilicity. However, when this group was removed, the variation between the mean values for lipophilicity and aromatic ring count across the remaining therapy areas was again found not to change in a meaningful manner, further highlighting the importance of these two parameters. The vast majority of drugs with a natural progenitor were formulated for either oral and/or injectable administration. Injectables were, on average, larger and more polar than drugs developed for oral, topical, and inhalation routes. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Category: esters-buliding-blocks).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Magnetic graphene based dispersive micro-solid-phase extraction coupled with liquid chromatography-tandem quadrupole mass spectrometry for analysis of nine non-steroidal anti-inflammatory drugs in livestock and poultry meat was written by Dong, Chanchan;Hu, Yanyun;Lu, Yaning;Song, Wei;Han, Fang;Zheng, Ping;Deng, Ning. And the article was included in Sepu in 2016.Product Details of 5003-48-5 The following contents are mentioned in the article:

A novel anal. method was developed for the determination of nine non-steroidal anti-inflammatory drugs (NSAIDs) in meat samples by magnetic graphene nanocomposite (Fe₃O₄-G) based on dispersive micro-solid-phase extraction (μ-SPE) coupled with liquid chromatog.-mass spectrometry detection. Samples were homogenized and extracted with acidified acetonitrile. After defatting with the high speed frozen centrifugation, the sample solutions were defatted with n-hexane followed by μ-SPE. Some important parameters influencing the extraction efficiency including the extraction time, the pH value of sample solution and the elution conditions were optimized. The limits of detection (LODs, S/N = 3) of the nine NSAIDs ranged from 0.2 to 8.2 μg/kg, and the limits of quantification (LOQs, S/N = 10) ranged from 0.5 to 25.4 μg/kg. The average recoveries were 83.3%-104.5% with the relative standard deviations between 1.2% and 6.8% obtained from samples spiked at LOQ, 2LOQ and 10LOQ levels. Compared with Sep-Pak Vac NH₂ and Oasis HLB cartridges, Fe₃O₄-G had excellent purification effect, high loading amounts and good reusability. The results demonstrate that the method provide a novel pretreatment technique for the determination of NSAID residues in meat samples. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Product Details of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Product Details of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics