Tag: 300-400

Pennelliiside D, a New Acyl Glucose from Solanum pennellii and Chemical Synthesis of Pennelliisides was written by Masimbula, Rishni;Kobayashi, Hiroto;Nakashima, Tenki;Nambu, Yurika;Kitaoka, Naoki;Matsuura, Hideyuki. And the article was included in Molecules in 2022.Reference of 604-69-3 The following contents are mentioned in the article:

Acyl glucoses are a group of specialized metabolites produced by Solanaceae. Solanum pennellii, a wild-type tomato plant, produces acyl glucoses in its hair-like epidermal structures known as trichomes. These compounds have been found to be herbicides, microbial growth inhibitors, or allelopathic compounds However, there are a few reports regarding isolation and investigation of biol. activities of acyl glucoses in its pure form due to the difficulty of isolation. Here, we report a new acyl glucose, pennelliiside D, isolated and identified from S. pennellii. Its structure was determined by 1D NMR and 2D NMR, together with FD-MS anal. To clarify the absolute configuration of the acyl moiety of 2-methylbutyryl in the natural compound, two possible isomers were synthesized starting from β-D-glucose pentaacetate. By comparing the spectroscopic data of natural and synthesized compounds of isomers, the structure of pennelliiside D was confirmed to be 3,4-O-diisobutyryl-2-O-((S)-2-methylbutyryl)-D-glucose. Pennelliiside D and its constituent fatty acid moiety, (S)-2-methylbutanoic acid, did not show root growth-inhibitory activity. Addnl., chem. synthesis pathways toward pennelliisides A and B were adapted to give 1,6-O-dibenzylpennelliisides A and B. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Reference of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Reference of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Design and development of surface modified epigallocatechin 3-gallate NanoCubogel for localized delivery to oral submucous fibrosis therapy was written by Mehta, Chetan Hasmukh;Narayan, Reema;Acharya, Shruthi;Nayak, Usha Yogendra. And the article was included in Journal of Drug Delivery Science and Technology in 2021.Electric Literature of C21H44O5 The following contents are mentioned in the article:

The present study is aimed at the development of stearylamine (SA) modified epigallocatechin 3-gallate (EGCG) loaded NanoCubes incorporated in mucoadhesive hydrogel (NanoCubogel), for the local treatment of oral submucous fibrosis (OSF) owing to its anti-fibrotic, anti-inflammatory, and oxygen radical scavenging properties with a better safety profile. The prepared NanoCubes and mucoadhesive NanoCubogel were evaluated and characterized for various parameters including in-vitro release and ex-vivo permeation studies. The optimized NanoCubes had a particle size, polydispersity index, zeta potential, and entrapment efficiency of 140.3 ± 1.12 nm, 0.173± 0.08, 46.9 ± 1.69 mV, and 59.0 ± 1.73%, resp. with cube-shaped morphol. The viscosity of the NanoCubogel was found to be 9253 ±112 cps. The SA modified NanoCubogel showed slower and sustained release of EGCG with higher permeation across buccal mucosa when compared to that of unmodified and pure EGCG. The formulation was found to be stable during the storage period. The developed NanoCubogel was capable of getting retained at the diseased site for a longer duration and releasing the EGCG locally for the desired time. Thus, the developed formulation may be used as an alternative treatment for OSF. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Electric Literature of C21H44O5).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Electric Literature of C21H44O5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effect of Conidiobolus coronatus on the cuticular and internal lipid composition of Tettigonia viridissima males was written by Golebiowski, Marek;Cerkowniak, Magdalena;Ostachowska, Aleksandra;Naczk, Aleksandra M.;Bogus, Mieczyslawa I.;Stepnowski, Piotr. And the article was included in Chemistry & Biodiversity in 2016.SDS of cas: 1731-94-8 The following contents are mentioned in the article:

Conidiobolus coronatus is an entomopathogennic fungus which has potential as a biol. control agent of insects. The cuticular and internal lipid composition of infected and non-infected Tettigonia viridissima males were analyzed by GC/MS. A total of 49 compounds were identified in the infected and non-infected males, including fatty acids, fatty acid Me esters, n-alkanes, alcs., sterols and other organic compounds The most abundant components of the cuticular and internal lipids of the insects were fatty acids. After exposure to C. coronatus, the cuticular lipids of the T. viridissima males contained 17 free fatty acids from C8 to C22, while the cuticular lipids of the non-infected insects contained only 15 fatty acids from C12 to C24. The cuticular and internal lipids of both the infected and the non-infected males also contained 5 fatty acid Me esters from C15 to C19, 7 n-alkanes from C25 to C34, 5 alcs. from C16 to C25, 5 sterols and the following six other organic compounds: azelaic acid, phenylacetic acid, glutaric acid, benzoic acid, sebacic acid and glycerol. The compounds which were present only in the cuticular lipids of the infected males could be due to fungal infection. This article is protected by copyright. All rights reserved. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8SDS of cas: 1731-94-8).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.SDS of cas: 1731-94-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Profiling of fatty acids composition in suet oil based on GC-EI-qMS and chemometrics analysis was written by Jiang, Jun;Jia, Xiaobin. And the article was included in International Journal of Molecular Sciences in 2015.Electric Literature of C20H40O2 The following contents are mentioned in the article:

Fatty acid (FA) composition of suet oil (SO) was measured by precolumn methylesterification (PME) optimized using a Box-Behnken design (BBD) and gas chromatog./electron ionization-quadrupole mass spectrometry (GC-EI-qMS). A spectral library (NIST 08) and standard compounds were used to identify FAs in SO representing 90.89% of the total peak area. The ten most abundant FAs were derivatized into FA Me esters (FAMEs) and quantified by GC-EI-qMS; the correlation coefficient of each FAME was 0.999 and the lowest concentration quantified was 0.01 μg/mL. The range of recovery of the FAMEs was 82.1%-8.7% (relative standard deviation 2.2%-.8%). The limits of quantification (LOQ) were 1.25-.95 μg/L. The number of carbon atoms in the FAs identified ranged from 12 to 20; hexadecanoic and octadecanoic acids were the most abundant. Eighteen samples of SO purchased from Qinghai, Anhui and Jiangsu provinces of China were categorized into three groups by principal component anal. (PCA) according to the contents of the most abundant FAs. The results showed SOs samples were rich in FAs with significantly different profiles from different origins. The method described here can be used for quality control and SO differentiation on the basis of the FA profile. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Electric Literature of C20H40O2).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Electric Literature of C20H40O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

From By-Products to Fertilizer: Chemical Characterization Using UPLC-QToF-MS via Suspect and Non-Target Screening Strategies was written by Panara, Anthi;Gikas, Evagelos;Thomaidis, Nikolaos S.. And the article was included in Molecules in 2022.Name: Glyceryl monostearate The following contents are mentioned in the article:

The increasing demands of agriculture and the food market have resulted in intensive agricultural practices using synthetic fertilizers to maximize production However, significant efforts have been made to implement more environmentally friendly procedures, such as composting, to overcome the adverse impact of these invasive practices. In the terms of this research, composting was applied to the production of two biofertilizers, using onion and mushroom byproducts as raw materials resp. The main purposes of this work were to identify the compounds that pass from the raw materials to the final products (onion-based and mushroom-based), as well as the characterization of the chem. profile of these final products following suspect and non-target screening workflows via UPLC-qToF-MS. Overall, 14 common compounds were identified in the onion and its final product, while 12 compounds were found in the mushroom and its corresponding product. These compounds belong to fatty acids, organic acids, and flavonoids, which could be beneficial to plant health. The determination of parameters, such as the pH, conductivity, organic matter, nitrogen content, and elemental anal., were conducted for the overall characterization of the aforementioned products. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Name: Glyceryl monostearate).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Name: Glyceryl monostearate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Astragali Radix-Codonopsis Radix-Jujubae Fructus water extracts ameliorate exercise-induced fatigue in mice via modulating gut microbiota and its metabolites was written by He, Pan;Chen, Lei;Qin, Xuemei;Du, Guanhua;Li, Zhenyu. And the article was included in Journal of the Science of Food and Agriculture in 2022.Recommanded Product: 31566-31-1 The following contents are mentioned in the article:

Astragali Radix (AR) and Codonopsis Radix (CR) are widely used as the tonic herbal medicine with efficacy of tonifying qi in traditional Chinese medicine (TCM), which showed significant antifatigue activities. In this study, AR and CR were combined, with Jujubae Fructus (JF) further added to improve the taste, to afford the ACJ extracts in the ratio of 2:1:2. The results showed that ACJ water extract exhibited antifatigue effect by the weight-loaded exhaustive swimming test in mice. The untargeted fecal metabolomic approach and 16S rRNA gene sequencing anal. showed that ACJ could improve exercise performance by regulating changes of gut metabolites and microbiota to alleviate fatigue. Four pathways were determined as the key pathways relating with its antifatigue effect, which included sphingolipid metabolism, glycerophospholipid metabolism, valine, leucine and isoleucine biosynthesis and D-arginine and D-ornithine metabolism Correlation anal. showed the complex association among bacteria, metabolites and phenotypes. In conclusion, this study revealed new perspectives to study the antifatigue mechanism of ACJ extracts from the gut microbiota, which provided the basis for further functional food development. 2022 Society of Chem. Industry. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Recommanded Product: 31566-31-1).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Recommanded Product: 31566-31-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Pharmaceutical compounds in aquatic environment in China: locally screening and environmental risk assessment was written by Chen, Yongshan;Xi, Xiuping;Yu, Gang;Cao, Qiming;Wang, Bin;Vince, Francois;Hong, Youwei. And the article was included in Frontiers of Environmental Science & Engineering in 2015.Recommanded Product: 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

An environmental risk assessment was performed for pharmaceutical compounds present in the aquatic environment of China. Predicted environmental concentration (PEC) of the compounds were calculated according to European Medicines Evaluation Agency (EMEA) guidelines. Available ecotoxicol. data compromised by applying a very conservative assessment factor (AF) were employed to calculate the predicted noeffect concentration (PNEC). The screening principle and the risk assessment were based on risk quotient (RQ), which derived from the PEC and related PNEC values. PEC results indicated that all the compounds except sulfadimethoxine and levocarnitine, should carry out phase II risk assessment in EMEA guideline. RQ values suggested that more than 36 pharmaceuticals may be imposed health threats to the aquatic environment; especially the antibiotic therapeutic class including amoxicillin, sulfasalazine, trimethoprim, oxytetracycline and erythromycin showed high RQ values. These substances with high RQ value (RQ≥1) were regarded as toppriority pharmaceuticals for control in the aquatic environment of China. However, the antibiotic substances which had low risk quotient (RQ <1), should be reassessed by its potentially induced resistance under low concentration in future. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Recommanded Product: 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Recommanded Product: 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Fatty acids analysis in Hypomesus olidus different parts by GC-MS was written by Chen, Ping;Wang, Jian-gang;Zhang, Li. And the article was included in Shipin Gongye (Shanghai, China) in 2014.Formula: C20H40O2 The following contents are mentioned in the article:

The research aimed to determine and analyze the fatty acid compositions of Hypomesus olidus different parts. The lip soluble components were extracted from Hypomesus olidus different parts by Soxhlet extraction resp. The extracted fatty acids were identified by gas chromatog.-mass spectrometry (GC-MS) after Me etherification treatment, and the relative percentage of each component was confirmed by peak-area normalization method. The test results show that, the fat content in different parts of Hypomesus olidus was obviously different, the head (37.25%), muscle (29.87%) and visceral (67.58%). The fatty acid compositions were similar in different parts of Hypomesus olidus, main components of unsaturated fatty acids were palmitoleic acid, 9-octadecenoic acid, all z, 5,8,11,14,17-eicosapentaenoic acid, 4,7,10,13,16,19-docosahexaenoic acid, etc; the main components of saturated fatty acids were palmitic acid, tetradecanoic acid, octadecanoic acid, etc. The distribution of fatty acid contents has the obvious difference in different parts, EPA and DHA content in the visceral was significantly higher than that in other parts. This result provides the nutrition and health value of Hypomesus olidus was higher and it had comprehensive development and utilization prospect. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Formula: C20H40O2).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Formula: C20H40O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

LC-MS detection of valuable or toxic ingredients and 48 chemical drugs added into Dahuoluo pills and Tongren Dahuoluo pills was written by Hu, Qing;Zhong, Jiqiang;Mao, Xiuhong;Wang, Ke;Ji, Shen. And the article was included in Yaowu Fenxi Zazhi in 2010.Name: 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

Sep. specific methods by LC/MSⁿ for the identification of 3 valuable or toxic ingredients and 48 analgesic and anti-inflammatory chem. drugs added illegally into Dahuoluo pills and Tongren Dahuoluo pills were established. The detection of 48 compounds was performed by Agilent 1100 HPLC/MSD trap using Agilent ZORBAX SB-C₁₈ (2.1 mm × 150 mm, 5 μm) column as stationary phase and 0.5% formic acid solution-methanol system as mobile phase. The gradient elution was done with as flow rate of 0.3 mL/min^-1. The detection of 3 valuable and toxic ingredients was performed by the same instrument and stationary phase, using water acetonitrile system in gradient elution as mobile phase. Pos. and neg. ionization switch autoscan mode was adopt using ESI source. Samples were extracted by Ultrasonic with methanol. Comparing with retention time and spectra of references in library set up by ourselves, the target compounds in sample are screened and identified. There were ephedrine detected in 229 samples, hyodeoxycholic acid detected in 41 samples, and loureirin B detected in 71 samples. The methods were accurate, fast and sensitive. It was the first time in China to report the LC/MS method, which could evaluate the quality of samples objectively. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Name: 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Name: 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mitochondrial Pro-Apoptotic Properties of Sinularia compressa from Persian Gulf against Breast Cancer Cells and Its Chemical Composition was written by Pour, Pardis Mohammadi;Yegdaneh, Afsaneh;Aghaei, Mahmoud;Kazemi, Fatemeh;Ghanadian, Mustafa. And the article was included in Nutrition and Cancer in 2022.Formula: C21H44O5 The following contents are mentioned in the article:

Locals in the Persian Gulf islands traditionally use Sinularia compressa to treat cancer. Therefore, this study deals with the cytotoxic activity of the soft coral Sinularia compressa chloroform extract (SCE), its pro-apoptotic activity, and the determination of its secondary metabolites. Cytotoxicity was done against MCF-7 and MDA-MB-231 and MCF-10A cells. Apoptosis induction was checked by flow cytometry. The DCFDA and JC-1 probes were used to assess the production of reactive oxygen species (ROS) and the mitochondrial transmembrane potential. Caspase-9, Bax, and Bcl-2 proteins were determined with ELISA Kit, and by western blot anal. SCE exhibited cytotoxic activity with an IC₅₀ value of 32.51 ± 0.70 μg/mL against MCF-7, and 8.53 ± 0.97 μg/mL against MDA-MB-231 cancer cells. The induction of the intrinsic apoptosis pathway was found by ROS generation, attenuation of Bcl-2 and induction of Bax proteins. It was supported by activation of caspase-9, increased apoptotic cells, as well as decrease of δψm. In the acute toxicity, there was no detectable sign of hepatic or renal toxicity in the SCE 100 mg/kg. GC mass and NMR identified bioactive compounds as one monoterpene, one sesquiterpene, five fatty acids, one phthalate, and two steroidal compounds This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Formula: C21H44O5).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Formula: C21H44O5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics