Tag: 300-400

Esterification of Microwave Induced Pyrolytic Oil from Sago Bark Waste was written by Wahi, Rafeah;Yahaya, Syamila Aimi;Lam, Su Shiung;Abdul Aziz, Sharifah Mona;Ngaini, Zainab. And the article was included in Waste and Biomass Valorization in 2020.Reference of 1731-94-8 The following contents are mentioned in the article:

In this study, microwave induced pyrolytic oil from sago bark (SB) was subjected to esterification to improve its properties. Improvement on properties of the pyrolytic oil was performed via esterification with ethanol and the presence of sulfuric acid as a catalyst. The optimum esterification condition was studied using general factorial design. The esterified oil (EO) showed improved properties with pH (4-6), reduced moisture content (2.95-3.45%), d. (0.9-1.1 g cm^-3), and acid value (39.3-123.4 mg KOH^-1 g^-1), and maintained the CV (20.2-21.6 MJ kg^-1). GC-MS anal. showed that EO was sulfur free, and low in carboxylic acid and oxygenated compounds The optimal esterification condition with optimum quality of EO was at 65°C temperature, 60 min reaction time and 1:1 ethanol to oil volume ratio. Results indicated that the EO can be potentially used in robust combustion engines upon properties refinement. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Reference of 1731-94-8).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Reference of 1731-94-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Glucopyranoside-Functionalized NHCs-Pd(II)-PEPPSI Complexes: Anomeric Isomerism Controlled and Catalytic Activity in Aqueous Suzuki Reaction was written by Zhou, Zhonggao;Xie, Qian;Li, Jing;Yuan, Yangyang;Liu, Yong;Liu, Yulong;Lu, Dongliang;Xie, Yongrong. And the article was included in Catalysis Letters in 2022.SDS of cas: 604-69-3 The following contents are mentioned in the article:

The first system controlled anomeric isomerism of glucopyranoside-functionalized N-heterocyclic carbenes based pyridine enhanced precatalyst preparation, stabilization and initiation type palladium(II) complexes (Glu-NHCs-Pd(II)-PEPPSI) were prepared and fully characterized. It is interesting to note that pure β-anomer PEPPSI complex was obtained, in which the Glu-substituent connects to the imidazole heterocycle ring N through ethoxy bridged anomeric carbon. In addition, the catalytic activities revealed that Glu-NHCs-Pd(II)-PEPPSI complexes are efficient catalysts for the aqueous Suzuki reaction. Under optimized conditions, a series of fluorene-cored functional materials with different aryl-substituents were synthesized through the Suzuki reaction with excellent yields. The Glu-NHCs-Pd(II)-PEPPSI complex containing bulky and rigid 2,5-dimethylphenyl group played an important role in maintaining the β conformation and improving the catalytic activity significantly. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3SDS of cas: 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.SDS of cas: 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Glycosylation of Tetrabromobisphenol A in Pumpkin was written by Hou, Xingwang;Yu, Miao;Liu, Aifeng;Wang, Xiaoyun;Li, Yanlin;Liu, Jiyan;Schnoor, Jerald L.;Jiang, Guibin. And the article was included in Environmental Science & Technology in 2019.Quality Control of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate The following contents are mentioned in the article:

Tetrabromobisphenol A (TBBPA) is the most widely used brominated flame retardant (BFR), and it bioaccumulates throughout the food chains. Its fate in the first trophic level, plants, is of special interest. In this study, a four-day hydroponic exposure of TBBPA at a concentration of 1μmol L^-1 to pumpkin seedlings was conducted. A nontarget screening method for hydrophilic bromine-containing metabolites was modified, based on both typical isotope patterns of bromine and mass defect, and used to process mass spectra data. A total of 20 glycosylation and malonyl glycosylation metabolites were found for TBBPA in the pumpkin plants. Representative glycosyl TBBPA reference standards were synthesized to evaluate the contribution of this glycosylation process. Approx. 86% of parent TBBPA was metabolized to form those 20 glycosyl TBBPAs, showing that glycosylation was the most dominant metabolism pathway for TBBPA in pumpkin at the tested exposure concentration This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Quality Control of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Quality Control of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mouth dissolving tablets: an innovative deviation in drug delivery system was written by Singh, Bharpoor;Bala, Rajni Miss;Gill, Naresh Singh. And the article was included in Journal of Pharmaceutical Sciences and Research in 2019.Category: esters-buliding-blocks The following contents are mentioned in the article:

The main aim of novel drug delivery system is to develop a dosage form which is easy to administer, free from side effects, exhibit immediate release and offer enhanced bioavailability for better patient compliance. To achieve such results oral drug delivery system, preferably, tablets are the most widely accepted dosage forms which offer numerous advantages. Beside those advantages, Dysphagia is the most common disadvantage of conventional tablets which is associated with number of conditions like sudden exposure of allergies, mental disability, motion sickness, unconsciousness, unavailability of water etc. To get rid from these problems several innovative drug delivery systems have been developed like Mouth Dissolving Tablets (MDT′s) which dissolve in saliva within a few seconds, when put on tongue. These tablets can be administered anywhere and anytime, without the need of water and are thus quite suitable for children, elderly and mentally disabled patients. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Category: esters-buliding-blocks).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Phytochemical screening and in vitro hepatoprotective activity of Ipomoea obscura was written by Meena, B.;Santhi, G.. And the article was included in World Journal of Pharmaceutical Research in 2018.Application In Synthesis of Methyl nonadecanoate The following contents are mentioned in the article:

The World Health Organization (WHO) estimates that 80% of the people of developing countries rely on traditional medicines, mostly plant derived drugs for their primary health needs. Medicinal and preventing specific ailments are considered to play a significant role in health care. The use of plants in traditional systems is an indispensable source of medicinal preparations Hundreds of species recognized as having medicinal value. Indeed, ′phytomedicines′ to link traditional and modern medicines. In the present study to investigate the phytochems., histochem., fluorescence, GCMS anal. and hepatoprotective activity of Ipomoea obscura leaves. The results of the present study concluded that I. obscura leaves may be a good source of phytochems., histochem., fluorescence, GCMS. Over all the leaves of I. obscura is a source of phytochems. and possess hepatoprotective activity that can be important in oxidative stress mediated diseases diabetic, cancer, arthritis etc. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Application In Synthesis of Methyl nonadecanoate).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Application In Synthesis of Methyl nonadecanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Total Synthesis of Pyrolaside B: Phenol Trimerization through Sequenced Oxidative C-C and C-O Coupling was written by Neuhaus, William C.;Kozlowski, Marisa C.. And the article was included in Angewandte Chemie, International Edition in 2020.Recommanded Product: 604-69-3 The following contents are mentioned in the article:

A facile method to oxidatively trimerize phenols using a catalytic aerobic copper system is described. The mechanism of this transformation was probed, yielding insight that enabled cross-coupling trimerizations. With this method, the natural product pyrolaside B (I) was synthesized for the first time. The key strategy used for this novel synthesis is the facile one-step construction of a spiroketal trimer intermediate II, which can be selectively reduced to give the natural product framework without recourse to stepwise Ullmann- and Suzuki-type couplings. As a result, pyrolaside B can be obtained expeditiously in five steps and 16% overall yield. Three other analogs were synthesized, thus highlighting the utility of the method, which provides new accessibility to this area of chem. space. A novel xanthene, III, was also synthesized through controlled Lewis acid promoted rearrangement of a spiroketal trimer. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Recommanded Product: 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

One-pot four-component tandem synthesis of novel sulfonamide-1, 2, 3-triazoles catalyzed by reusable copper (II)-adsorbed on mesoporous silica under ultrasound irradiation was written by Talha, Aicha;Mourhly, Asmae;Tachallait, Hamza;Driowya, Mohsine;El Hamidi, Adnane;Arshad, Suhana;Karrouchi, Khalid;Arsalane, Said;Bougrin, Khalid. And the article was included in Tetrahedron in 2021.Synthetic Route of C16H22O11 The following contents are mentioned in the article:

A green and efficient synthesis of new sulfonamide-1,2,3-triazoles in heterogeneous conditions was developed. The procedure involved one-pot four-component tandem sulfonamidation/azidation/1,3-dipolar cycloaddition (1,3-DC) reactions under a cooperative effect of ultrasound irradiation and Cu (II) supported on amorphous mesoporous silica [mSiO₂-Cu (II)] catalysis at room temperature in aqueous medium. In addition, the 1,4-disubstituted 1,2,3-triazoles were synthesized by regioselective and chemoselective methods to afford the pure products in excellent yields and short reaction times under ultrasonic irradiation The supported catalyst was prepared from copper (II) nitrate by simple method using ultrasound activation and characterized by X-ray diffraction (XRD), Brunauer-Emmett-Teller (BET) method and Barrett-Joyner-Halenda (BJH) method. Also, the catalyst was easily prepared, stable, efficient, selective and reusable under ultrasonic conditions. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Synthetic Route of C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Synthetic Route of C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Double network oleogels co-stabilized by hydroxypropyl methylcellulose and monoglyceride crystals: Baking applications was written by Jiang, Qinbo;Yu, Zijuan;Meng, Zong. And the article was included in International Journal of Biological Macromolecules in 2022.Name: Glyceryl monostearate The following contents are mentioned in the article:

Edible double network oleogels were prepared by hydroxypropyl methylcellulose (HPMC) and glyceryl monostearate (GMS) by the cryogel-templated method. Hot GMS soybean oil solutions were absorbed by HPMC cryogels, which were further homogenized and cooled to form oleogels containing both the HPMC network and GMS network. The crystal network constructed by GMS crystal clusters significantly enhanced the mech. and rheol. attributes of oleogels. Both the HPMC network and the GMS network were built up due to hydrogen bonds. According to the normalization anal. of FTIR and the deepening of the shift of the absorption peak, hydrogen bonds could also be formed between HPMC and GMS to connect the two independent networks. Double network oleogels were further used to fabricate cookies and cakes, assessed by the texture profile anal. The combination of the HPMC network and GMS network in preparing oleogels will promote the application of oleogels as the fat replacer. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Name: Glyceryl monostearate).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Name: Glyceryl monostearate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Accurate prediction of the toxicity of benzoic acid compounds in mice via oral without using any computer codes was written by Keshavarz, Mohammad Hossein;Gharagheizi, Farhad;Shokrolahi, Arash;Zakinejad, Sajjad. And the article was included in Journal of Hazardous Materials in 2012.COA of Formula: C17H15NO5 The following contents are mentioned in the article:

Most of benzoic acid derivatives are toxic, which may cause serious public health and environmental problems. Two novel simple and reliable models are introduced for desk calculations of the toxicity of benzoic acid compounds in mice via oral LD₅₀ with more reliance on their answers as one could attach to the more complex outputs. They require only elemental composition and mol. fragments without using any computer codes. The first model is based on only the number of carbon and hydrogen atoms, which can be improved by several mol. fragments in the second model. For 57 benzoic compounds, where the computed results of quant. structure-toxicity relationship (QSTR) were recently reported, the predicted results of two simple models of present method are more reliable than QSTR computations. The present simple method is also tested with further 324 benzoic acid compounds including complex mol. structures, which confirm good forecasting ability of the second model. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5COA of Formula: C17H15NO5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.COA of Formula: C17H15NO5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Click Pt(IV)-carbohydrates pro-drugs for treatment of osteosarcoma was written by Moynihan, Eoin;Bassi, Giada;Ruffini, Andrea;Panseri, Silvia;Montesi, Monica;Velasco-Torrijos, Trinidad;Montagner, Diego. And the article was included in Frontiers in Chemistry (Lausanne, Switzerland) in 2021.Synthetic Route of C16H22O11 The following contents are mentioned in the article:

The selectivity vs. cancer cells has always been a major challenge for chemotherapeutic agents and in particular for cisplatin, one of the most important anticancer drugs for the treatment of several types of tumors. One strategy to overtake this challenge is to modify the coordination sphere of the metallic center with specific vectors whose receptors are overexpressed in the tumoral cell membrane, such as monosaccharides. In this paper, we report the synthesis of four novel glyco-modified Pt(IV) pro-drugs, based on cisplatin scaffold, and their biol. activity against osteosarcoma (OS), a malignant tumor affecting in particular adolescents and young adults. The sugar moiety and the Pt scaffold are linked exploiting the Copper Azide Alkyne Cycloaddition (CUAAC) reaction, which has become the flagship of click chem. due to its versatility and mild conditions. Cytotoxicity and drug uptake on three different OS cell lines as well as CSCs (Cancer Stem Cell) are described. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Synthetic Route of C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Synthetic Route of C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics