Tag: 300-400

Conformationally Switchable Glycosyl Donors was written by Holmstroem, Thomas;Pedersen, Christian Marcus. And the article was included in Journal of Organic Chemistry in 2019.Product Details of 604-69-3 The following contents are mentioned in the article:

Glycosyl donors functionalized with 2,2′-bipyridine moieties on the 3-OH and 6-OH or the 2-OH and 4-OH undergo a conformational change when forming 1:1 complexes with Zn²⁺ ions. The pyranoside ring of the zinc complexes adopted axial-rich skew boat conformations. The reactivities of the two glycosyl donors were investigated by performing a series of glycosylations in the presence or absence of Zn²⁺ ions. These glycosylations suggested a decrease in reactivity when binding Zn²⁺. The conformational effect of binding Zn²⁺ was therefore studied using a third glycosyl donor, unable to undergo conformational changes when binding Zn²⁺. From competition experiments, it was observed that the binding-induced conformational change increased the reactivity slightly compared to the glycosyl donor unable to undergo a conformational change. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Product Details of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Product Details of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

LC-MS/MS screening for 36 chemical components in health food and Chinese traditional patent medicine was written by Li, Dan;Wen, Hongmei;Cui, Fuchun;Huang, Ya;Guo, Chun;Sun, Xiarong;Yang, Jingping. And the article was included in Yaowu Fenxi Zazhi in 2010.Safety of 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

A liquid chromatog.-tandem mass chromatog. (LC-MS/MS) method for the simultaneous screening 36 chem. components in health food and Chinese Traditional Patent Medicine was established. This method involves liquid chromatog.-tandem mass spectrometry, the separation was conducted by Sunfire C₁₈ (2.1 mm × 100 mm, 5.0 μm). The mobile phase consisted of 0.1% formic acid and methanol (25:75). The target compounds were analyzed with LC-MS/MS-ESI. Multiple-reaction monitoring (MRM) was used to screen 36 chem. components in health food and Chinese Traditional Patent Medicine. A fast and sensitive liquid chromatog. mass spectrometric (LC/MS) method for the simultaneous screening of 36 chem. components was described. The LOD of these substances were below 20 ng. The method was sufficiently selective and sensitive to detect chem. components in health food and Chinese Traditional Patent Medicine. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Safety of 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Safety of 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Phosphorus and metal removal combined with lipid production by the green microalga Desmodesmus sp.: An integrated approach was written by Rugnini, L.;Costa, G.;Congestri, R.;Antonaroli, S.;Sanita di Toppi, L.;Bruno, L.. And the article was included in Plant Physiology and Biochemistry in 2018.COA of Formula: C20H40O2 The following contents are mentioned in the article:

This work focused on the potential of Desmodesmus sp. to be employed for wastewater bioremediation and biodiesel production The green microalga was grown in a culture medium with a phosphorus (P) content of 4.55 mg L^-1 simulating an industrial effluent; it was also exposed to a bimetal solution of copper (Cu) and nickel (Ni) for 2 days. P removal was between 94 and 100%. After 2 days of exposure to metals, 94% of Cu and 85% of Ni were removed by Desmodesmus sp. Adsorption tests showed that the green microalga was able to remove up to 90% of Cu and 43% of Ni in less than 30 min. The presence of metals decreased the lipid yield, but biodiesel quality from the biomass obtained from metal exposed samples was higher than that grown without metals. This result revealed that this technol. could offer a new alternative solution to environmental pollution and carbon-neutral fuel generation. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8COA of Formula: C20H40O2).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.COA of Formula: C20H40O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Nanostructured lipid carriers for the encapsulation of phloretin: preparation and in vitro characterization studies was written by Gu, Liyuan;Sun, Rui;Wang, Wenjuan;Xia, Qiang. And the article was included in Chemistry and Physics of Lipids in 2022.SDS of cas: 31566-31-1 The following contents are mentioned in the article:

Phloretin is a powerful antioxidant with many effects, such as anti-cancer, anti-inflammatory, promoting cell renewal, delaying aging and so on. However, the application of phloretin was limited by its low water solubility, low absorption in vivo and unstable properties. A phloretin-loaded nanostructured lipid carrier was designed with a high-pressure homogenization technique. The mean particle size of phloretin NLC was 137.40 ± 3.27 nm, and the Polydispersity index (PdI) value was 0.237 ± 0.005. The encapsulation efficiency was 96.68% ± 0.06%. Transmission electron microscopy images showed that the phloretin-loaded nanostructured lipid carriers were spherical. Phloretin in NLC showed a sustained release pattern in vitro. The results showed that phloretin NLC is more suitable for absorption than phloretin ethanol solution, and NLC can be a promising carrier for phloretin in the food industry. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1SDS of cas: 31566-31-1).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.SDS of cas: 31566-31-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Study on relation of dissolution of benorilate tablets with drug concentration in human plasma was written by Chen, Zongdai;Du, Kairong;Zeng, Jingze;Zhang, Da;Deng, Fu. And the article was included in Yaowu Fenxi Zazhi in 2002.Reference of 5003-48-5 The following contents are mentioned in the article:

The relation between dissolution of benorilate tablets and benorilate concentration in human plasma was analyzed. Sodium lauryl sulfate (1%) solution was used as the medium, and paddles method was used with sampling after 45 min. UV spectrophotometry was adapted for the determination of dissolution of benorilate tablets. The concentration of benorilate in human plasma was estimated by using a HPLC method which was developed to determine the hydrolytic products of benorilate paracetamol and salicylic acid. p-Dimethylaminobenzaldehyde was used as the internal standard The relationship between dissolution and concentration of benorilate in human plasma was treated statistically. A good relationship existed between the dissolution and pharmacokinetic parameters AUC, C_max [r=0.968; 0.985 (n=5), r_0.01,3=0.959]. The method could control the sample quality effectively. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Reference of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Reference of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Polybenzyls from Gastrodia elata, their agonistic effects on melatonin receptors and structure-activity relationships was written by Chen, Si-Yue;Geng, Chang-An;Ma, Yun-Bao;Huang, Xiao-Yan;Yang, Xiao-Tong;Su, Li-Hua;He, Xiao-Feng;Li, Tian-Ze;Deng, Zhen-Tao;Gao, Zhen;Zhang, Xue-Mei;Chen, Ji-Jun. And the article was included in Bioorganic & Medicinal Chemistry in 2019.Name: (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate The following contents are mentioned in the article:

Gastrodia elata is a famous traditional Chinese herb with medicinal and edible application. In this study, nine polybenzyls (1-9), including six new ones (2-5, 7 and 9), were isolated from the EtOAc extract of G. elata. Five compounds 1, 3, 4, 6 and 8 were found to activate melatonin receptors. Especially, compound 1 showed agonistic effects on MT₁ and MT₂ receptors with EC₅₀ values of 237 and 244 μM. For better understanding their structure-activity relationships (SARs), ten polybenzyl analogs were further synthesized and assayed for their activities on melatonin receptors. Preliminary SARs study suggested that two para-hydroxy groups were the key pharmacophore for maintaining activity. Mol. docking simulations verified that compound 1 could strongly interact with MT₂ receptor by bonding to Phe 118, Gly 121, His 208, Try 294 and Ala 297 residues. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Name: (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Name: (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Selective Promotion of Adhesion of Shewanella oneidensis on Mannose-Decorated Glycopolymer Surfaces was written by Young, Thomas D.;Liau, Walter T.;Lee, Calvin K.;Mellody, Michael;Wong, Gerard C. L.;Kasko, Andrea M.;Weiss, Paul S.. And the article was included in ACS Applied Materials & Interfaces in 2020.Product Details of 604-69-3 The following contents are mentioned in the article:

Using glycopolymer surfaces, the authors have stimulated Shewanella oneidensis bacterial colonization and induced where the bacteria attach on a mol. pattern. When the Me α-D-mannopyranoside competitor was codeposited with the cell culture, however, the mannose-based polymer was not significantly different from bare gold surfaces. The necessity for equilibration between Me α-D-mannopyranoside and the cell culture to remove the enhancement suggests that the retention of cells on glycopolymer surfaces is kinetically controlled and is not a thermodn. result of the cluster glycoside effect. The MshA lectin appears to facilitate the improved adhesion observed The findings that the surfaces studied here can induce stable initial attachment and influence the ratio of bacterial strains on the surface may be applied to harness useful microbial communities. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Product Details of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Product Details of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Qualitative organic analysis. I. Identification of drugs by principal components analysis of standardized thin-layer chromatographic data in four eluent systems was written by Musumarra, Giuseppe;Scarlata, Giuseppe;Cirma, Giuseppe;Romano, Guido;Palazzo, Silvana;Clementi, Sergio;Giulietti, Gianfranco. And the article was included in Journal of Chromatography in 1985.Related Products of 5003-48-5 The following contents are mentioned in the article:

Identification of drugs by principal component anal. of standardized retention factor (R_F) values in 4 eluent systems, [EtOAc [141-78-6]-MeOH [67-56-1]-30% NH₄OH (85:10:15), cyclohexane  [110-82-7]-PhMe [108-88-3]-Et₂NH [109-89-7] (65:25:10), EtOAc-CHCl₃  [67-66-3] (50:50), and Me₂CO [67-64-1] with the plate dipped in KOH solution] provided a 2-component model which accounts for 73% of the total variance. The scores plot allowed the restriction of the range of inquiry to a few candidates. This result is of great practical significance in anal. toxicol., especially when account is taken of the cost, the time, the anal. instrumentation and the simplicity of the calculations required by the method. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Related Products of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Related Products of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

β-Galactosidase instructed supramolecular hydrogelation for selective identification and removal of senescent cells was written by Xu, Tengyan;Cai, Yanbin;Zhong, Xinglong;Zhang, Le;Zheng, Debing;Gao, Zhengfeng;Pan, Xianmei;Wang, Fuqiang;Chen, Minsheng;Yang, Zhimou. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2019.Safety of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate The following contents are mentioned in the article:

The identification and removal of senescent cells is very important to improve human health and prolong life. In this study, we introduced a novel strategy of β-galactosidase (β-Gal) instructed peptide self-assembly to selectively form nanofibers and hydrogels in senescent cells. We demonstrated that the in situ formed nanofibers could alleviate endothelial cell senescence by reducing p53, p21, and p16^INK4a expression levels. We also demonstrated that our strategy could selectively remove senescent endothelial cells by inducing cell apoptosis, with an increase in the BAX/BCL-2 ratio and caspase-3 expression. Our study reports the first example of enzyme-instructed self-assembly (EISA) by a sugar hydrolase, which may lead to the development of supramol. nanomaterials for the diagnosis and treatment of many diseases, such as cancer, and for other applications, such as wound healing and senescence. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Safety of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Safety of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Ultraviolet spectrophotometry in drug control. XXVIII. New pharmaceuticals with chromophores of benzene rings in the molecules. 3. Effect of substitution and solvents was written by Kracmar, J.;Kracmarova, J.. And the article was included in Cesko-Slovenska Farmacie in 1982.Application of 5003-48-5 The following contents are mentioned in the article:

UV spectra of 10 drugs with a benzene chromophore, baclofen  [1134-47-0], lorcainide  [59729-31-6], DL-ibuprofen  [15687-27-1], DL-mexiletine  [31828-71-4], clonidine  [4205-90-7], ketoconazole  [65277-42-1], terbutaline  [23031-25-6], propafenone  [54063-53-5], xipamide  [14293-44-8], and benorilate  [5003-48-5] were described. Solvent effects on absorption shifts, absorption maximum of characteristic bands, and Beer’s law were discussed and specific absorbances calculated Use of these spectra for characterization and determination are discussed. Concentration ranges for determination in μg amounts are given. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Application of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Application of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics