Tag: 300-400

Synthesis and Biochemical Evaluation of an Artificial, Fluorescent Glucosinolate (GSL) was written by Glindemann, Carina Patrizia;Backenkoehler, Anita;Strieker, Matthias;Wittstock, Ute;Klahn, Philipp. And the article was included in ChemBioChem in 2019.Reference of 604-69-3 The following contents are mentioned in the article:

The synthesis of the first example of a fluorescent glucosinolate (GSL)-BODIPY conjugate based on an azide-containing artificial GSL precursor (GSL-N₃) is reported. Biochem. evaluation of the artificial GSLs revealed that the compounds are converted to the corresponding isothiocyanates in the presence of myrosinase. Furthermore, myrosinase-catalyzed hydrolysis in the presence of plant specifier proteins yielded the expected alternative products, namely nitriles. The easy assembly of the fluorescent GSL-BODIPY conjugate by click chem. from GSL-N₃ holds potential for application as a fluorescence labeling tool to investigate GSL-associated processes. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Reference of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Reference of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of Glycosylated 1-Deoxynojirimycins Starting from Natural and Synthetic Disaccharides was written by Liu, Bing;van Mechelen, Jeanine;van den Berg, Richard J. B. H. N.;van den Nieuwendijk, Adrianus M. C. H.;Aerts, Johannes M. F. G.;van der Marel, Gijsbert A.;Codee, Jeroen D. C.;Overkleeft, Herman S.. And the article was included in European Journal of Organic Chemistry in 2019.Related Products of 604-69-3 The following contents are mentioned in the article:

Iminosugars are an important class of natural products and have been subject to extensive studies in organic synthesis, bio-organic chem. and medicinal chem., yet only a limited number of these studies are on glycosylated iminosugars. Here, a general route of synthesis is presented towards glycosylated 1-deoxynojirimycin derivatives based on the oxidation-reductive amination protocol that in the past has also been shown to be a versatile route towards 1-deoxynojirimycin. The strategy can be applied on com. disaccharides, as shown in four examples, as well as on disaccharides that are not com. available and are synthesized for this purpose, as shown by a fifth example. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Related Products of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Related Products of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Preparation and characterization of aspirin and benorilate was written by Wang, Jin;Sun, Wei. And the article was included in Huaxue Yu Nianhe in 2009.SDS of cas: 5003-48-5 The following contents are mentioned in the article:

Aspirin was synthesized with using sodium acetate as the catalyst. The dosage of the catalyst, the reaction time and temperature which had effects on the yield of aspirin was studied. The results showed that sodium acetate had better catalytic activity, when the dosage of sodium acetate, in the system was 3%, reaction temperature was 55 °C, reaction time was 50 min, and the yield of aspirin could reach 81.9%. The synthesis process of benorilate which taken aspirin and acetaminophen as raw materials was improved and the effect of different solvents on the yield of benorilate was investigated. The yield of benorilate was up to 90% in the system of toluene-water medium. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5SDS of cas: 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.SDS of cas: 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Supercritical CO₂ extraction technology on basil seeds oil and its component analysis was written by Yimamu, Huerxidan;Zhang, Jun-ping;Waili, Aihemiding;Kasimu, Rena;Yili, Abulimiti;Aisa, Hajiakber. And the article was included in Shipin Yanjiu Yu Kaifa in 2016.Category: esters-buliding-blocks The following contents are mentioned in the article:

The studies on the optimum conditions for the extraction of basil seeds oil by supercritical CO₂ fluid were carried out. The primary and secondary effect factors on the extraction of basil seeds oil by supercritical CO₂ fluid were as followed: pressure > time > temperature The optimum conditions were: extraction pressure 300 Pa, extraction temperature 45°C, extraction time 3 h. Under these conditions, the maximum extraction rate was 17.05%. The fatty acid composition of basil seeds oil was mainly composed of linolenic acid (85.76%), palmitic acid (8.54%) and stearate (5.1%), in which the content of unsaturated fatty acids reached 86.35%. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Category: esters-buliding-blocks).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

GC-MS determination of phospholipid fatty acids in soil was written by Zhang, Li-ping;Wang, Chuan;Zhou, Qiao-hong;Wang, Ya-fen;Wu, Zhen-bin. And the article was included in Lihua Jianyan, Huaxue Fence in 2015.Safety of Methyl nonadecanoate The following contents are mentioned in the article:

GC-MS was applied to the determination of phospholipid fatty acids in soil. The sample was added into KOH solution with methanol as solvent. After Me esterification, fatty acid Me esters were extracted with hexane. The extract was separated on an Agilent DB-5MS column. Full-scanning mode and SIM were adopted in MS. Linear relationships were found between the peak area and the mass concentration of the 26 fatty acids Me esters in definite ranges, with detection limits (3S/N) in the range of 0.0012 – 0.2959 mg · L^-1. Recovery rates measured by standard addition method were in the range of 108% – 115%, and RSDs (n = 7) were in the range of 3.2% – 6.4%. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Safety of Methyl nonadecanoate).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Safety of Methyl nonadecanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Imidazolium-Linked Azido-Functionalized Guerbet Glycosides: Multifunctional Surfactants for Biofunctionalization of Vesicles was written by Goh, Ean Wai;Heidelberg, Thorsten;Duali Hussen, Rusnah Syahila;Salman, Abbas Abdulameer. And the article was included in ACS Omega in 2019.Name: (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate The following contents are mentioned in the article:

Aiming for glycolipid-based vesicles for targeted drug delivery, cationic Guerbet glycosides with spacered click functionality were designed and synthesized. The cationic charge promoted the distribution of the glycolipids during the formulation, thereby leading to homogeneously small vesicles. The pos. surface charge of the vesicles stabilizes them against unwanted fusion and promotes interactions of the drug carriers with typical neg. charge-dominated target cells. High bioconjugation potential of the functionalized glycolipids based on the copper-catalyzed azide alkyne cycloaddition makes them highly valuable components for targeted drug delivery systems. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Name: (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Name: (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effect of indomethacin on the cyclic AMP-dependent protein kinase was written by Catalan, R. Edgardo;Aragones, Maria D.;Martinez, A. M.;Armijo, Manuel;Pina, Manuel. And the article was included in European Journal of Pharmacology in 1980.Safety of 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

Indomethacin (I) [53-86-1] inhibited cyclic AMP-dependent protein kinase [9026-43-1] activity in small intestine in in vivo experiments An inverse pattern of variation was exhibited by acetylsalicylic acid [50-78-2], eterylate [62992-61-4], and benorylate [5003-48-5]; acetyl-p-aminophenol [103-90-2] was inactive. Indomethacin, acetylsalicylic acid, eterylate, and benorylate increased protein kinase activity in liver, lung, and heart. The in vivo effect of indomethacin was confirmed by in vitro experiments with small intestine and heart protein kinases. Indomethacin may affect protein kinase activity in a tissue-specific way. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Safety of 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Safety of 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Absence of mutagenic activity of benorylate, paracetamol and aspirin in the Salmonella/mammalian microsome test was written by Jasiewicz, M. L.;Richardson, J. C.. And the article was included in Mutation Research Letters in 1987.Application of 5003-48-5 The following contents are mentioned in the article:

Benorylate  [5003-48-5] and its 2 major hydrolysis products, paracetamol  [103-90-2], and aspirin  [50-78-2], were examined for mutagenicity in the Salmonella/mammalian microsome screening test. The compounds were tested in 6 strains of S. typhimurium in the presence and absence of a rat-liver microsome activation system. Benorylate did not show evidence of mutagenic activity, with or without metabolic activation, at 0.006-3 mg/plate. Paracetamol and aspirin likewise did not show any evidence of mutagenic activity at 0.1-50 and 0.01-50 mg/plate, resp. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Application of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Application of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Specificity data of the salicylate assay by fluorescent polarization immunoassay was written by Koel, Marlies;Nebinger, Peter. And the article was included in Journal of Analytical Toxicology in 1989.Product Details of 5003-48-5 The following contents are mentioned in the article:

The recently developed Abbott Laboratories fluorescent polarization immunoassay (FPIA) for salicylates in serum was studied. The cross-reactivity test of the assay was performed with 20 substances that showed a similar chem. structure as salicylic acid. A chem. substitution on the 5-position of the salicylate formula enhanced the cross-reactivity. 5-Methylsalicylic acid, diflunisal, salazosulfapyridin, and 5-aminosalicylic acid (5-ASA) showed a significant cross-reactivity with 1200%, 222%, 153%, and 122%, resp. Diflunisal and salazosulfapyridin at a similar therapeutic serum level as salicylic acid can produce false pos. salicylate results, in case of unknown medication of these compounds This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Product Details of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Product Details of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Passive absorption simulated by active principles on artificial lipid membranes was written by Robert, H.;Guyot-Herdmann, A. M.;Lefebvre, C.. And the article was included in Lille Medical (1956-1981) in 1980.Recommanded Product: 5003-48-5 The following contents are mentioned in the article:

The apparatus of Dibbern and Resomat was used for the study of the simulation of the digestive absorption of active ingredients, alone or in the galenic form, as a function of pH. The artificial membrane was made of a polyamide or cellulose acetate impregnated with lipids and phospholipids. The plasmatic phase used was a phosphate buffer (pH 7.35) and the digestive medium was an enzyme-free artificial gastric liquid (pH 1.2). Absorption curves of compounds such as Na salicylate [54-21-7], phenobarbital [50-06-6], and papaverine [58-74-2], as a function of pH are given. The effect of excipients on the absorption of active ingredients in galenic form was also studied by this apparatus This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Recommanded Product: 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Recommanded Product: 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics