Tag: 300-400

The synthesis of vitamin E sugar 1,2-orthoesters was written by Walejko, Piotr;Baj, Aneta. And the article was included in Monatshefte fuer Chemie in 2019.Quality Control of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate The following contents are mentioned in the article:

Abstract: In this study, 3,4,6-tri-O-acetyl-1,2-O-(1-tocopheroxyethylidene)-α-D-glucopyranose (sugar 1,2-orthoester) was synthesized with good and moderate yields in the presence of an N,N-diisopropylethylamine/tetrabutylammonium iodide system via a reaction of α-tocopherol with sugar halides. The utility of sugar α- and β-chlorides, α-bromides, and α-iodide in the synthesis of aryl (α-tocopherol, 2,2,5,7,8-pentamethylchroman-6-ol and 2,6-dimethylphenol) 1,2-orthoesters was investigated. The stereoselective formation of exo-1,2-orthoesters was confirmed using ¹H and ¹³C NMR spectroscopy. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Quality Control of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Quality Control of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Exploring QSARs of some analgesic compounds by PC-ANN was written by Deeb, Omar;Drabh, Mojahed. And the article was included in Chemical Biology & Drug Design in 2010.Synthetic Route of C17H15NO5 The following contents are mentioned in the article:

Quant. structure-activity relationship study was performed to understand analgesic activity for a set of 95 heterogeneous analgesic compounds This study was performed by using the principal component-artificial neural network modeling method, with application of eigenvalue ranking factor selection procedure. The results obtained by principal component-artificial neural network give advanced regression models with good prediction ability using a relatively low number of principal components. A 0.834 correlation coefficient was obtained using principal component-artificial neural network with six extracted principal components. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Synthetic Route of C17H15NO5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Synthetic Route of C17H15NO5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Photocatalyzed reductive fluoroalkylation of 2-acetoxyglycals towards the stereoselective synthesis of α-1-fluoroalkyl-C-glycosyl derivatives was written by Mora Flores, Erwin W.;Uhrig, Maria Laura;Postigo, Al. And the article was included in Organic & Biomolecular Chemistry in 2020.Related Products of 604-69-3 The following contents are mentioned in the article:

A benign, efficient, regio- and stereoselective protocol for the syntheses of α-1-fluoroalkyl-C-glycosyl compounds bearing CF₃, C₄F₉, and C₆F₁₃ substituents on the anomeric carbon has been developed by a new methodol. starting from 2-acetoxyglycals for the first time. Remarkably, the reactions proceeded in only one step, through the visible light-photocatalyzed reductive fluoroalkylation of 2-acetoxyglycals by means of an Ir photocatalyst and employed com. available fluoroalkyl iodides n-C_nF_2n+1-I (n = 1, 4, 6) as a source of fluoroalkyl radicals. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Related Products of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Related Products of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Benorylate interaction with ethoxybenzamide and lorazepam was written by Huh, In Hoi;Lee, Myung Hwan. And the article was included in Yakhak Hoechi in 1979.COA of Formula: C17H15NO5 The following contents are mentioned in the article:

Concurrent administration of equal doses of benorylate (I) [5003-48-5] and ethoxybenzamide [27043-22-7] increased the inhibiting effect on the acetic acid-induced writhing syndrome of mice over that obtained with each drug alone and similarly increased the analgesic response to the hot plate method. The synergistic analgesic effect of the combined administration of I and lorazepam [846-49-1] was also significant. The antipyretic effect of the combined administration of half-doses of I and ethoxybenzamide on rat pyrexia induced by yeast or TTG was similar to that obtained with each drug sep. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5COA of Formula: C17H15NO5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.COA of Formula: C17H15NO5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Investigation of the unsaponifiable and saponifiable matters of Pachypodium lamerei drake leaves and stems by GC/MS was written by El-Kashef, Dina F.;Hamed, Ashraf N. E.;Khalil, Hany E.;Kamel, Mohamed S.. And the article was included in Journal of Pharmacognosy and Phytochemistry in 2014.Computed Properties of C20H40O2 The following contents are mentioned in the article:

Pachypodium lamerei Drake (family Apocynaceae) is native to Madagascar and is known as Madagascar palm. The present study shows that, the unsaponifiable matter of P. lamerei contains various compounds identified as hydrocarbons (5.43%), pregnane (0.92%), steroids (11.54%), triterpenes (8.78%) as well as other oxygenated compounds (61.3%). While, the saponifiable matter contains twenty compounds from which ten were identified as Me esters of saturated fatty acids (32.31%) in addition to hydroxylated fatty acids (9.96%) whereas ten fatty acids (57.73%) couldn’t be identified. This is the first record of the GC/MS anal. for genus Pachypodium. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Computed Properties of C20H40O2).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Computed Properties of C20H40O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of 2′-paclitaxel 2-deoxy-2-fluoro-glucopyranosyl carbonate for specific targeted delivery to cancer cells was written by Meng, Xin;Lian, Xujing;Li, Xiao;Ya, Qiang;Li, Tingshen;Zhang, Yongmin;Yang, Yang;Zhang, Yan. And the article was included in Carbohydrate Research in 2020.Application of 604-69-3 The following contents are mentioned in the article:

A novel 2-fluorodeoxyglucose conjugated derivative of paclitaxel was efficiently synthesized using a linker between 2′-OH of paclitaxel and C1-hydroxyl group of 2-fluorodeoxyglucose. In preparation of the prodrug, allyl carbonates were selected as the protective group and the efficient one-step removal of allyloxycarbonyl groups at the end of the synthesis using palladium chem. gave the target mol. in good yield. The prodrug not only improved the pharmaceutical properties of paclitaxel, such as solubility and stability, but also demonstrated enhanced cytotoxicity and selectivity for cancer cells and less toxicity toward normal HUVEC cells. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Application of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Application of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Solvent- and catalyst-free transamidation of unprotected glycosyl carboxamides was written by Bensalah, Fouzia Ouadah;Bil, Abed;Wittine, Karlo;Bellahouel, Salima;Lesur, David;Markovic, Dean;Laclef, Sylvain. And the article was included in Organic & Biomolecular Chemistry in 2019.Reference of 604-69-3 The following contents are mentioned in the article:

The transamidation reactions of unprotected mono- and disaccharidic carboxamides with various primary and secondary aryl, heterocyclic or aliphatic amines are described. This new method is green and atom efficient and gives good to high yields. Notably, the conditions do not require either a solvent or a catalyst and give ammonia as a single byproduct. The described coupling reaction is compatible with a variety of functional groups and was used in the synthesis of various glycosidic derivatives and biol. relevant glycolipids. A plausible reaction mechanism involving an intermol. H-bond activation of the starting carboxamides is proposed. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Reference of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Reference of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

The effect of anti-inflammatory drugs on retinal dystrophy in the rat was written by Dewar, A. J.;Barron, Gillian;Reading, H. W.. And the article was included in Toxicology and Applied Pharmacology in 1977.Application In Synthesis of 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

The effects of acetylsalicylate [50-78-2], cortisone acetate [50-04-4], and Benorylate and (4-acetamidophenyl 2-acetoxybenzoate) [5003-48-5] on the process of retinal degeneration in albino and pigmented retinal dystrophic rats were examined Chronic administration of these agents for periods up to 8 wk elicited no improvement observable histol. in either the albino or pigmented strains, although all 3 drugs produceda marginal reduction in the loss of retinal DNA in the former. Thus, chronic antiinflammatory drug administration is largely ineffective in retarding the progress of retinal degeneration in the retinal dystrophic rat. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Application In Synthesis of 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application In Synthesis of 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

GC-MS analysis of phytochemicals, fatty acids and antimicrobial potency of dry christmas lima beans was written by Marimuthu, Krishnaveni;Nagaraj, Nandhini;Ravi, Dhanalakshmi. And the article was included in International Journal of Pharmaceutical Sciences Review and Research in 2014.COA of Formula: C20H40O2 The following contents are mentioned in the article:

Seeds are very important for the plants to reproduce continuously in the existing world. The human life depends partly on the seeds derived from plants either by means of cooked or raw or in the form of active principles in case of pharmacol. use. So, it is essential to study the nutrients present in the seeds and also its fatty acid content as it is an important factor in giving antimicrobial activity. The components were assessed by means of anal. technique called GC-MS. The obtained results showed that it contains higher oleic acid and 9-Octadecenoic acid (Z)-Me ester and found to be effective against fungi Aspergillus flavus. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8COA of Formula: C20H40O2).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.COA of Formula: C20H40O2

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effect of eterylate, benorylate and acetylsalicylic acid on glycemia in normal and experimental diabetic rats was written by Alonso, S.;Ortega, M. P.;Armijo, M.. And the article was included in Archivos de Farmacologia y Toxicologia in 1983.Computed Properties of C17H15NO5 The following contents are mentioned in the article:

The effects of acetylsalicylic acid (I) [50-78-2] on blood sugar levels in normal and streptozotocin-diabetic rats were compared with those of its (acetylamino)phenyl ester, benorylate (II) [5003-48-5], and its [(acetylamino)phenoxy]ethyl ester, eterylate [62992-61-4], at equimolar doses. All 3 drugs had a hypoglycemic effect in diabetic animals when administered orally at a high dose (500 mg/100 g feed, calculated as I), but only II decreased blood sugar levels in normal rats. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Computed Properties of C17H15NO5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Computed Properties of C17H15NO5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics