Tag: 300-400

Composition and difference of fatty acid components in Phellodendron chinense and Phellodendron amurense was written by Xue, Juan;Zhang, Hongwei;Sun, Yichun;Mi, Yingying;Kuang, Haixue;Wang, Qiuhong. And the article was included in Guizhou Nongye Kexue in 2015.SDS of cas: 1731-94-8 The following contents are mentioned in the article:

The fatty acid Me ester of extracts from P. hinense and P. amurense was isolated and identified by GC-MS to explore composition and difference of fatty acid in P. hinense and P. amurense. 65 And 14 components were isolated from P. chinense and P. murense resp. 53 And 14 components were identified sep. The fatty acid of P. chinense mainly contains linolelaidic acid (16.059%), jinoleic acid (14.232%), oleic acid (13.354%) and hexadecanoic acid (7.528%). The fatty acid of P. amurense mainly contains linoleic acid (62.047%), oleic acid (6.905%), linolenic acid (6.283%) and hexadecanoic acid (2.959%). This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8SDS of cas: 1731-94-8).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. SDS of cas: 1731-94-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Antiproliferative and apoptotic potential of methotrexate lipid nanoparticles in a murine breast cancer model was written by Surve, Chaitali;Banerjee, Ananya;S, Anupriya;Chakraborty, Rajasree;Kumar, Dhiraj;Butti, Ramesh;Gorain, Mahadeo;Parida, Sabyasachi;Kundu, Gopal C.;Shidhaye, Supriya;Patnaik, Srinivas. And the article was included in Nanomedicine (London, United Kingdom) in 2022.Quality Control of Glyceryl monostearate The following contents are mentioned in the article:

To evaluate the efficacy of novel methotrexate-loaded nanoparticles (MTX-NPs) in vitro and in vivo in the treatment of breast cancer. MTX-NPs were tested for cellular uptake, cell viability, cell cycle, cellular wound migration and changes in tumor volume using characterized NPs. The solid lipid NPs (SLNPs) showed strong cellular uptake, increased apoptosis, controlled cytotoxicity at lower IC₅₀ of methotrexate and a sizable reduction in tumor burden. MTX-NP oral formulation can be a promising candidate in breast cancer treatment with improved cellular uptake and in vivo efficacy. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Quality Control of Glyceryl monostearate).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Quality Control of Glyceryl monostearate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Identification of benorilate tablets by infrared spectrophotometric method was written by Lu, Hong. And the article was included in Heilongjiang Yiyao in 2008.Electric Literature of C17H15NO5 The following contents are mentioned in the article:

The objective of this paper is to establish a rapid and exclusive method for the identification of benorilate tablets. The sample crystallized with methanol, and identified by the IR spectrophotometric method. The results show that the IR absorption spectrum of the benorilate tablets was completely in conformity with that of the reference substance and the standard spectrum of paracetamol in IR spectrum album of drugs issued by Chinese Pharmacopeia Committee. It was concluded that the method is specific, rapid and convenient and it can be used for the identification of benorilate tablets. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Electric Literature of C17H15NO5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Electric Literature of C17H15NO5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Comparative effectiveness of topically applied nonsteroid antiinflammatory agents on guinea pig skin was written by Sarkany, I.;Gaylarde, P. M.;Brock, A. P.. And the article was included in Clinical and Experimental Dermatology in 1981.Safety of 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

Twelve nonsteroid antiinflammatory agents and 2 antioxidants, known to have prostaglandin synthesis inhibitory activity, were tested for their ability to suppress irritant-induced epidermal thickening in the guinea pig. Salicylates and indomethacin [53-86-1] were the most active. From previous experience, this activity is thought to correspond to the behavior of these drugs in human skin. Since no antiinflammatory activity was demonstrated by the antioxidants, the unifying concept of prostaglandin synthesis inhibition as an explanation for suppression of inflammation is questioned. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Safety of 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Safety of 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Expanding chemical space by para-C-H arylation of arenes was written by Maiti, Sudip;Li, Yingzi;Sasmal, Sheuli;Guin, Srimanta;Bhattacharya, Trisha;Lahiri, Goutam Kumar;Paton, Robert S.;Maiti, Debabrata. And the article was included in Nature Communications in 2022.Formula: C16H22O11 The following contents are mentioned in the article:

A robust catalytic system that displayed unique efficacy toward para-arylation of highly functionalized substrates such as drug entities, giving access to structurally diversified biaryl scaffolds, e.g., I was developed. This diversification process provided access to an expanded chem. space for further exploration in drug discovery. Further, the applicability of the transformation was realized through the synthesis of drug mols. bearing a biphenyl fragment. Computational and exptl. mechanistic studies further provided insight into the catalytic cycle operative in this versatile C-H arylation protocol. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Formula: C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Formula: C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Studies on effectiveness of diclofenac potassium was written by Yang, Fangju;Fang, Zhiping;Yang, Xiaomin;Zhang, Qi;Zhou, Suzhen. And the article was included in Huaxi Yaoxue Zazhi in 2000.Quality Control of 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

The effectiveness and acute toxicity of diclofenac K (DK) manufactured in China were studied in rats and mice with carrageenin-induced paw edema and ear edema . DK (5-10 mg kg^-1, oral) significantly inhibited carrageenin-induced paw edema and ear edema in rats and mice and also inhibited the pain in writhing model and hot plate method in mice. The LD₅₀ for DK po in mice was (160.04 ± 43.49) mg kg^-1 compared with that of (182.58 ± 30.64) mg.kg^-1 for DK i.p. The results showed that the anti-inflammatory and analgesic effects of DK were better than those of benorilate. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Quality Control of 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Quality Control of 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Concise Synthesis of 1-Thioalkyl Glycoside Donors by Reaction of Per-O-acetylated Sugars with Sodium Alkanethiolates under Solvent-Free Conditions was written by Feng, Guang-Jing;Luo, Tao;Guo, Yang-Fan;Liu, Chun-Yang;Dong, Hai. And the article was included in Journal of Organic Chemistry.COA of Formula: C16H22O11 The following contents are mentioned in the article:

A relatively green method for synthesizing 1-thioalkyl glycosides has been developed, where sodium alkanethiolates were used to react with per-O-acetylated sugars instead of odorous alkyl mercaptans in the presence of BF₃·Et₂O without the use of solvents under mild conditions. Furthermore, we found that 1,2-trans-β-thioglycosides can be converted into corresponding 1,2-cis-α-thioglycosides in the presence of trifluoromethanesulfonic acid in nonpolar solvents under mild conditions. This provides a simple and efficient new approach for synthesizing challenging 1,2-cis-α-thioglycosides. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3COA of Formula: C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.COA of Formula: C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis and antiproliferative evaluation of some novel quinazolin-4(3H)-one derivatives was written by Salem, Marwa Sayed;Al-Mabrook, Selima Ali Mohamed;El-Hashash, Maher Abd El-Aziz Mahmoud. And the article was included in Journal of Heterocyclic Chemistry in 2020.Related Products of 604-69-3 The following contents are mentioned in the article:

A series of novel quinazolinone derivatives was designed and synthesized. The antiproliferative activities were evaluated in vitro using MTT assay against hepatocellular carcinoma (HepG-2) and mammary gland breast cancer (MCF-7). The preliminary bioassay results demonstrated that tested compounds exhibited antiproliferation in various degrees. Triazole moiety enhanced the activity against the two cell lines when incorporating with quinazolinone moiety in a single mol. framework. Acetohydrazide-quinazolinone derivative showed strong activity against the two cancer cells comparable to that of doxorubicin. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Related Products of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Related Products of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Comprehensive drug screening in urine using solid-phase extraction and combined TLC and GC/MS identification was written by Lillsunde, P.;Korte, T.. And the article was included in Journal of Analytical Toxicology in 1991.Safety of 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

A simple and sensitive identification system for the detection of a broad spectrum of drugs is described. ChemElut extraction tubes were used for the isolation of drugs from human urine. Specimens were screened by TLC and confirmed by GC/mass spectrometry. Special procedures for buprenorphine, cannabinoids, cocaine, LSD, morphine, phencyclidine, halogenated hydrocarbons, paracetamol, and alcs. were used. This system is useful for screening samples in misuse, impaired driving, poisoning, and other forensic cases. It covers about 300 substances including all potentially abused drugs and their metabolites. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Safety of 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Safety of 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Study of the inhibition of platelet aggregation provoked by etherylate, benorylate and its molecular components in comparison with acetylsalicylic acid was written by Ortega, P.;Alonso, S.;Navarro, J. L.. And the article was included in Archivos de Farmacologia y Toxicologia in 1978.Reference of 5003-48-5 The following contents are mentioned in the article:

In vitro platelet aggregation was inhibited by eterylate (I) [62992-61-4] to a greater extent than by benorylate [5003-48-5] or acetylsalicylic acid [50-78-2]. In rats given a single dose of I the inhibition of platelet aggregation induced by ADP was 2 times greater than that of rats treated with acetylsalicylic acid, whereas in rats given 7 doses of either drug the inhibition of platelet aggregation by I was 1.2 times that observed in rats treated with acetylsalicylic acid. When the inducing agent was collagen the activity of both drugs was equal. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Reference of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Reference of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics