Tag: 300-400

Optimization of a mathematical topological pattern for the prediction of antihistaminic activity was written by Duart, M. J.;Garcia-Domenech, R.;Anton-Fos, G. M.;Galvez, J.. And the article was included in Journal of Computer-Aided Molecular Design in 2001.Name: 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

Mol. topol. was used to develop a math. model capable of classifying compounds according to antihistaminic activity. The equations used for this purpose were derived using multi-linear regression and linear discriminant anal. The topol. pattern of activity obtained allows the reliable prediction of antihistaminic activity in drugs frequently used for other therapeutic purposes. Based on the results, the proposed pattern is seemingly only valid for drugs that interact with histamine through competitive inhibition with H1 receptors. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Name: 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Name: 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Cleavage of Carboxylic Esters by Aluminum and Iodine was written by Sang, Dayong;Yue, Huaxin;Fu, Yang;Tian, Juan. And the article was included in Journal of Organic Chemistry in 2021.Formula: C17H15NO5 The following contents are mentioned in the article:

A one-pot procedure for deprotecting carboxylic esters such as ArC(O)OR [Ar = Ph, 2-HOC₆H₄, 4-BrC₆H₄, etc.; R = Me, Bn, iPr, t-But] using aluminum and iodine under nonhydrolytic conditions was described. Cleavage of lactones afforded the corresponding ω-iodoalkylcarboxylic acids ICH₂(CH₂)nC(O)OH [n = 2, 4, 12]. Aryl acetylates undergo deacetylation with the participation of the neighboring group. This method enabled the selective cleavage of alkyl carboxylic esters in the presence of aryl esters. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Formula: C17H15NO5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Formula: C17H15NO5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

One step stereoselective synthesis of oxazoline-fused saccharides and their conversion into the corresponding 1,2-cis glycosylamines bearing various protected groups was written by Dong, Sanfeng;Zhao, Yitian;Shi, Yulong;Xu, Zhijian;Shen, Jingshan;Jia, Qi;Li, Yiming;Chen, Kaixian;Li, Bo;Zhu, Weiliang. And the article was included in Organic & Biomolecular Chemistry in 2021.Application of 604-69-3 The following contents are mentioned in the article:

Herein we disclosed a straightforward synthesis of oxazoline-fused saccharides (oxazolinoses) from peracetylated saccharides and benzonitriles under acidic conditions with stoichiometric amounts of water. The d. functional theory (DFT) calculations have revealed the origin of the stereoselectivity and the key role of water in promoting the departure of the acetyl group at C-2. The resulting oxazolinoses can be concisely converted into the corresponding 1,2-cis glycosylamines bearing various protected groups, allowing the access to schisandrin derivatives This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Application of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Application of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Palladium-Catalyzed Chemoselective Negishi Cross-Coupling of Bis[(pinacolato)boryl]methylzinc Halides with Aryl (Pseudo)Halides was written by Lee, Hyojae;Lee, Yeosan;Cho, Seung Hwan. And the article was included in Organic Letters in 2019.SDS of cas: 604-69-3 The following contents are mentioned in the article:

We describe a palladium-catalyzed chemoselective Negishi cross-coupling of a bis[(pinacolato)boryl]methylzinc halide with aryl (pseudo)halides. This reaction affords an array of benzylic 1,1-diboronate esters, which can serve as useful synthetic handles for further transformations. The developed coupling reaction is compatible with various functional groups and can be easily scaled up. The coupling of bis[(pinacolato)boryl]methylzinc halides with pharmaceuticals and the subsequent late-stage manipulations demonstrate the power of the developed protocol. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3SDS of cas: 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.SDS of cas: 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Study on synthesis of some paracetamol derivatives was written by Truong, Phuong;Huynh, Thi Hai Van;Trinh, My Hoang. And the article was included in Tap Chi Duoc Hoc in 2009.Reference of 5003-48-5 The following contents are mentioned in the article:

Propacetamol hydrochloride and benorilate (paracetamol derivatives) were obtained from low-cost materials, such as aspirin [i.e., 2-(acetyloxy)benzoic acid], paracetamol, SOCl₂, chloroacetic acid and diethylamine. The process was simple and appropriate for Vietnamese manufacturing conditions. The purity of propacetamol hydrochloride and benorilate was confirmed by thin layer chromatog. Propacetamol hydrochloride was assayed by non-aqueous titration method while benorilate was determined by application of a nitrogen method. Both products conformed to standards by BP 2005. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Reference of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Reference of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Studies on the antinflammatory and analgesic effects of eterylate, benorylate and acetylsalicylic acid was written by Pina, M.;Armijo, M.. And the article was included in Archivos de Farmacologia y Toxicologia in 1978.Related Products of 5003-48-5 The following contents are mentioned in the article:

In rats in which edema was provoked by injection of carrageen, eterylate (I) [62992-61-4], benorylate (II) [5003-48-5], and acetylsalicylic acid (III) [50-78-2] (100,158.48, and 251.18 mg/kg, resp.) showed the same degree of antiinflammatory activity. III, at 200, 300, and 450 mg/kg, and the equivalent doses of I and II had the same analgesic effect in rats. The 50% EDs were 156.13, 185.51, and 251.41 for I, II, and III, resp. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Related Products of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Related Products of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Diastereoselective Synthesis of Thioglycosides via Pd-Catalyzed Allylic Rearrangement was written by Li, Jiagen;Wang, Ming;Jiang, Xuefeng. And the article was included in Organic Letters in 2021.Computed Properties of C16H22O11 The following contents are mentioned in the article:

Stereoselective glycosylation is challenging in carbohydrate chem. Herein, stereoselective thioglycosylation of glycals via palladium-catalyzed allylic rearrangement yields various substituents on α-isomer thioglycosides. Two comprehensive series of aryl and benzyl thioglycosides were obtained via a combination of thiosulfates with glycals derived from glucose, arabinose, galactose, and rhamnose. Furthermore, diosgenyl α-L-rhamnoside and isoquercitrin achieved selectivity via stereospecific [2,3]-sigma rearrangements of α-sulfoxide-rhamnoside and α-sulfoxide-glucoside, resp. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Computed Properties of C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Computed Properties of C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Optimization of synthesis process of benorilate was written by Ma, Yan. And the article was included in Huagong Shikan in 2014.Computed Properties of C17H15NO5 The following contents are mentioned in the article:

The purpose of the research is to optimize the synthesis process of benorilate by designing orthogonal test using esterification reaction solvent, esterification time and phase transfer catalyst as single factors. The influence degree of esterification reaction solvent, esterification time and phase transfer catalyst to the yield of benorilate is: solvent >time >phase transfer catalyst. The best combination on synthesis of benorilate was as follows: using benzene as solvent, esterification time of 1.5h, and using tetrabutylammonium bromide as phase transfer catalyst. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Computed Properties of C17H15NO5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters are more polar than ethers but less polar than alcohols. They participate in hydrogen bonds as hydrogen-bond acceptors, but cannot act as hydrogen-bond donors, unlike their parent alcohols. This ability to participate in hydrogen bonding confers some water-solubility.Computed Properties of C17H15NO5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Determination of benorilate in benorilate tablets by HPLC was written by Gu, Qiuzin. And the article was included in Zhongguo Yaoshi (Wuhan, China) in 2007.Computed Properties of C17H15NO5 The following contents are mentioned in the article:

An HPLC method was established for determination of benorilate in benorilate tablets. The chromatog. column was ZORBAX Eclipse XDB-C₁₈ column (150 mm × 4.6 mm, 5 μm) at 30°, using methanol-water (50:50) as mobile phase at a flow rate of 1.0 mL/min. The detection wavelength was set at 240 nm. The calibration curve was linear within the range of 20-180 μg/mL (r = 0.999 9) for benorilaten. The average recovery of benorilate was 100.0% with RSD of 1.2% (n = 6). The method is suitable for the determination of benorilate in benorilate tablets. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Computed Properties of C17H15NO5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Computed Properties of C17H15NO5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Copper-Catalyzed Anomeric O-Arylation of Carbohydrate Derivatives at Room Temperature was written by Verdelet, Tristan;Benmahdjoub, Sara;Benmerad, Belkacem;Alami, Mouad;Messaoudi, Samir. And the article was included in Journal of Organic Chemistry in 2019.Electric Literature of C16H22O11 The following contents are mentioned in the article:

Direct and practical anomeric O-arylation of sugar lactols with substituted arylboronic acids has been established. Using copper catalysis at room temperature under an air atm., the protocol proved to be general, and a variety of aryl O-glycosides have been prepared in good to excellent yields. Furthermore, this approach was extended successfully to unprotected carbohydrates, including α-mannose, and it was demonstrated here how the interaction between carbohydrates and boronic acids can be combined with copper catalysis to achieve selective anomeric O-arylation. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Electric Literature of C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Electric Literature of C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics