Tag: 300-400

Synthesis of rare sugar isomers through site-selective epimerization was written by Wang, Yong;Carder, Hayden M.;Wendlandt, Alison E.. And the article was included in Nature (London, United Kingdom) in 2020.Recommanded Product: (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate The following contents are mentioned in the article:

Here we report the preparation of rare sugar isomers directly from biomass carbohydrates through site-selective epimerization reactions. Mechanistic studies establish that these reactions proceed under kinetic control, through sequential steps of hydrogen-atom abstraction and hydrogen-atom donation mediated by two distinct catalysts. This synthetic strategy provides concise and potentially extensive access to this valuable class of natural compounds This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Recommanded Product: (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Recommanded Product: (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

GC-MS analysis on fat-soluble components in Yao medicine Angiopteris fokiensis was written by Zhang, Yun-yun;Yang, Hai-chuan;Li, Jia;Jiang, Ping-chuan. And the article was included in Zhongguo Yaofang in 2015.Application In Synthesis of Methyl nonadecanoate The following contents are mentioned in the article:

This paper is to provide reference for chem. composition anal. in Angiopteris fokiensis. The fat-soluble components in A. fokiensis were extracted and separated The separated fat-soluble compounds were analyzed and identified by GC-MS after Me esterification. Totally 52 compounds were detected and 43 compounds of those were identified. They were mainly organic acids and sterol-like compounds The 43 components are first identified in A. fokiensis. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Application In Synthesis of Methyl nonadecanoate).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Application In Synthesis of Methyl nonadecanoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

New bronchodilators selected by molecular topology was written by Rios-Santamarina, I.;Garcia-Domenech, R.;Galvez, J.;Cortijo, J.;Santamaria, P.;Morcillo, E.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 1998.Safety of 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

Mol. topol. has been applied to find new lead compounds with bronchodilator activity. Among the selected compounds stands out 3-(1H-tetrazol-5yl)-9H-thioxanthene-9-one-10,10-dioxide, anthrarobin, 9-oxo-9H-thioxantene-3-carboxylic-10,10-dioxide acid, acenocoumarol and griseofulvin, with a percentage of relaxation, at 0.1 mM, of 91, 92, 85, 69 and 74 %, resp. Theophylline shows a correspondent value of 77% (E_max=100% at 1 mM). This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Safety of 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Safety of 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Palladium-Catalyzed C-S Bond Formation as a Tool for Latent-Active Glycosylation was written by Hedberg, Christinne;Jessen, Kamilla S.;Hansson, Rikke F.;Heuckendorff, Mads;Jensen, Henrik H.. And the article was included in Organic Letters in 2020.Application of 604-69-3 The following contents are mentioned in the article:

A high-yielding palladium-catalyzed C-S cross-coupling is presented for utilization in carbohydrate chem. as a key transformation for attachment of a second chelating sulfur atom that allows the exploitation of a latent-active glycosylation strategy with Cu(OTf)₂ as the promoter. The novel approach employs o-Br-benzyl thioglycosides as latent glycosyl donors and o-SMe-benzyl thioglycosides as the active counterparts. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Application of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Application of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Mechanism of skin penetration by cercariae of S. japonicum and screening of preventive drugs was written by Wang, Yusheng;Chen, Jiayu;Song, Peizhao;Wang, Wenni;Zhou, Xiankun;Hu, Huiqin. And the article was included in Huaxi Yike Daxue Xuebao in 1989.Reference of 5003-48-5 The following contents are mentioned in the article:

The prostaglandin inhibitors aspirin and ibuprofen given orally or i.p. to mice inhibited skin penetration by Schistosoma japonicum cercariae; the penetration was not affected by the receptor antagonists diphenhydramine, chlorpheniramine, atropine, and practolol, but was inhibited by praziquantel. PGE₁ in the cercaria-penetrated mouse skin was higher than that in normal skin, suggesting that prostaglandins are necessary for the penetration. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Reference of 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Reference of 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of the aglycon of scorzodihydrostilbenes B and D was written by Weimann, Katja;Braun, Manfred. And the article was included in Beilstein Journal of Organic Chemistry in 2019.Name: (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate The following contents are mentioned in the article:

Benzyl- and methyl-protected 2,4-dihydroxyacetophenones were added under ruthenium catalysis to 4-methoxy- and 3,4- dimethoxystyrene in a completely regioselective manner. Thus, oxygenated dihydrostilbenes were obtained that feature the skeleton of scorzodihydrostilbenes – antioxidative agents that were recently isolated from Scorzonera radiata. Selective deprotection liberated the corresponding phenols, among them the aglycon of scorzodihydrostilbenes B and D. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Name: (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Name: (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Comparative experimental studies in animals and humans on gastrointestinal blood loss following antirheumatic pharmacotherapy was written by Palme, G.;Koeppe, P.. And the article was included in Arzneimittel-Forschung in 1978.Recommanded Product: 5003-48-5 The following contents are mentioned in the article:

Oral administration of equimolar amounts of the antirheumatic drugs acetylsalicylic acid (I) [50-78-2] (4.5 g/70 kg) and benorilate (II) [5003-48-5] (6.0 g/70 kg) to rats and human subjects caused gastrointestinal blood loss, as measured by whole-body ⁵⁹FeCl₃-retention studies. In both rats and man, the daily blood loss caused by I was ∼2-fold greater than that by II. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Recommanded Product: 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Recommanded Product: 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Catalyst-Free and Scalable Process for Synthesis of Novel MAP4K4 Inhibitor DMX-5804 and Its Glyco-Conjugates was written by Eeda, Venkateswararao;Awasthi, Vibhudutta. And the article was included in Organic Process Research & Development in 2021.Computed Properties of C16H22O11 The following contents are mentioned in the article:

Here, the process development of scalable and practical synthesis of DMX-5804 I was reported. Process optimization resulted in the following, removal of transition metals from the process and reduced duration of reactions, a streamlined process with significantly improved yields using low-cost raw materials, importantly, microwave-assisted reactions were removed, column purification avoided throughout the process, and crystallized products showed over 95% purity in each step. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Computed Properties of C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Computed Properties of C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis and Analysis of Natural-Product-Like Macrocycles by Tandem Oxidation/Oxa-Conjugate Addition Reactions was written by Lee, Hyunji;Sylvester, Kayla;Derbyshire, Emily R.;Hong, Jiyong. And the article was included in Chemistry – A European Journal in 2019.Quality Control of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate The following contents are mentioned in the article:

Here, a strategy for the preparation of a broad natural-product-like macrocyclic library e.g., I by using the tandem allylic oxidation/oxa-conjugate addition and macrocyclization reactions is reported. Cheminformatic analyses demonstrate that this tetrahydropyran-containing macrocyclic library shows a significant overlap with natural products in the chem. space. This approach can be used for designing libraries that may probe more deeply into natural-product-like space. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Quality Control of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Quality Control of (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

A screening test for pharmaceuticals, drugs and insecticides with reversed-phase liquid chromatography – retention data of 560 compounds was written by Daldrup, T.;Michalke, P.;Boehme, W.. And the article was included in Chromatography Newsletter in 1982.SDS of cas: 5003-48-5 The following contents are mentioned in the article:

High-performance reversed-phase liquid chromatog. retention data are given. The relative retention times were calculated as the ratio of retention times of compound and reference compound 5-(p-methylphenyl)-5-phenylhydantoin. The UV detector wavelength was 220 nm, where most of the compounds gave a good response. The sensitivity of the method for each compound is rated from very good to bad. Two solvent programs and a prepacked column C-18 SIL-X-10 were used for the anal. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5SDS of cas: 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.SDS of cas: 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics