Tag: 300-400

Prediction and screening of biologically active compounds in honeysuckle (Lonicera japonica) by biopartitioning micellar chromatography was written by Gan, Yuan;Liang, Yan;Chen, Han;Xue, Jin-Tao;Yan, Xin-Yu;Xiong, Dong-Mei;Chen, Cong;Ye, Li-Ming;Xu, Ting;Chen, Yu. And the article was included in Asian Journal of Chemistry in 2014.Category: esters-buliding-blocks The following contents are mentioned in the article:

A new in vitro method, based on the retention data in biopartitioning micellar chromatog., is validated for prediction and screening of bioactive components of honeysuckle (Lonicera japonica). Relationships between the capacity factors of honeysuckle extracts and chem. drugs with related curative effects are studied. Finally, statistical anal. and predictive model were obtained. The results reveal that anti-inflammatory, antipyretic and analgesic effects are the main efficacy of honeysuckle, antibiotic and antiviral effects take second place, effect of lowering blood pressure, high blood fat and blood sugar is the weakest. Besides, with further relevant Matlab programming function, the probability of the components associated with different effects can be obtained by calculating the honeysuckle capacity factors, so as to identify which peak represents the active ingredient in the chromatogram and which is the main pharmacol. action. The use of biopartitioning micellar chromatog. is simple, reproducible and can provide key information for predicting and screening bioactive constituents of honeysuckle extracts This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Category: esters-buliding-blocks).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Uptake and release of species from carbohydrate containing organogels and hydrogels was written by Pan, Abhishek;Roy, Saswati G.;Haldar, Ujjal;Mahapatra, Rita D.;Harper, Garry R.;Low, Wan Li;De, Priyadarsi;Hardy, John G.. And the article was included in Gels in 2019.Formula: C16H22O11 The following contents are mentioned in the article:

Hydrogels are used for a variety of tech. and medical applications capitalizing on their three-dimensional (3D) crosslinked polymeric structures and ability to act as a reservoir for encapsulated species (potentially encapsulating or releasing them in response to environmental stimuli). In this study, carbohydrate-based organogels were synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization of a β-D-glucose pentaacetate containing methacrylate monomer (Ac-glu-HEMA) in the presence of a di-vinyl crosslinker; these organogels could be converted to hydrogels by treatment with sodium methoxide (NaOMe). These materials were studied using solid state 13C cross-polarization/magic-angle spinning (CP/MAS) NMR, Fourier transform IR (FTIR) spectroscopy, and field emission SEM (FE-SEM). The swelling of the gels in both organic solvents and water were studied, as was their ability to absorb model bioactive mols. (the cationic dyes methylene blue (MB) and rhodamine B (RhB)) and absorb/release silver nitrate, demonstrating such gels have potential for environmental and biomedical applications. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Formula: C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Formula: C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effect of crude oil composition on ternary composite alkali-surfactant-polymer flooding was written by Sun, Zhe;Sun, Xuefa;Lu, Xiangguo;Chen, Xin;Yu, Qin;Tian, Chunyu. And the article was included in Shiyou Huagong in 2016.Reference of 1731-94-8 The following contents are mentioned in the article:

The interactions between oil/water samples from different districts in Daqing oilfield with ternary composite alkali-surfactant-polymer (ASP) system were studied. The effects of the crude oil compositions on the crude oil production increment with ASP system and the properties of the produced fluid were studied. The oil/water samples, extracted active ingredients, raffinate oil and sulfur content in the oil phase were analyzed by means of FTIR, GC-MS and XRF. It was showed that, the characteristic peaks of the active ingredients in the oil/water samples accorded with the features of typical saturated monocarboxylic acids (fatty acids and naphthenic acids). The concentration of n-alkanes with heavy component in the raffinate oil from the Lamadian oil/water sample was higher, and its composition was closer to that of the surfactant (heavy alkylbenzene sulfonates). It was indicated that, the interfacial tensions between the ASP system and the active ingredients in the oil/water samples or the raffinate oil were high, but there were ultra-low interfacial tensions between the ASP system and the crude oils. This study involved multiple reactions and reactants, such as Methyl nonadecanoate (cas: 1731-94-8Reference of 1731-94-8).

Methyl nonadecanoate (cas: 1731-94-8) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Reference of 1731-94-8

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Azoacetylenes for the Synthesis of Arylazotriazole Photoswitches was written by Pfaff, Patrick;Anderl, Felix;Fink, Moritz;Balkenhohl, Moritz;Carreira, Erick M.. And the article was included in Journal of the American Chemical Society in 2021.Product Details of 604-69-3 The following contents are mentioned in the article:

Authors report a modular approach toward novel arylazotriazole photoswitches and their photophys. characterization. Addition of lithiated TIPS-acetylene to aryldiazonium tetrafluoroborate salts gives a wide range of azoacetylenes, constituting an underexplored class of stable intermediates. In situ desilylation transiently leads to terminal arylazoacetylenes that underwent copper-catalyzed cycloadditions (CuAAC) with a diverse collection of organoazides. These include complex mols. derived from natural products or drugs, such as colchicine, taxol, tamiflu, and arachidonic acid. The arylazotriazoles display near-quant. photoisomerization and long thermal Z-half-lives. Using the method, authors introduce for the first time the design and synthesis of a diacetylene platform. It permits implementation of consecutive and diversity-oriented approaches linking two different conjugants to independently addressable acetylenes within a common photoswitchable azotriazole. This is showcased in the synthesis of several photoswitchable conjugates, with potential applications as photoPROTACs and biotin conjugates. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Product Details of 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Esters contain a carbonyl center, which gives rise to 120° C–C–O and O–C–O angles. Unlike amides, esters are structurally flexible functional groups because rotation about the C–O–C bonds has a low barrier. Their flexibility and low polarity is manifested in their physical properties; they tend to be less rigid (lower melting point) and more volatile (lower boiling point) than the corresponding amides. Product Details of 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Solvent-Free Glycosylation from per-O-Acylated Donors Catalyzed by Methanesulfonic Acid was written by Traboni, Serena;Bedini, Emiliano;Silipo, Alba;Vessella, Giulia;Iadonisi, Alfonso. And the article was included in European Journal of Organic Chemistry in 2021.Computed Properties of C16H22O11 The following contents are mentioned in the article:

The huge importance of carbohydrates and their derivatives in biomedical and industrial applications call for the development of streamlined and sustainable procedures for their synthetic elaboration. Here reported a novel glycosylation method based on direct activation of readily available per-O-acylated (acetylated or benzoylated) donors, promoted under air by methanesulfonic acid as a cheap and green catalyst in the absence of any solvent. Besides the beneficial avoidance of toxic and polluting organic solvents, these conditions were found critical for activating such poorly reactive donors with a very small catalyst loading (only 5 mol %), instead of stoichiometric Lewis acid promoters typically employed. Desired glycosides were quickly obtained, in most cases with high 1,2-trans stereoselectivity. Other main advantages over reported glycosylation with similar donors are the limited stoichiometric excess of the acceptor (or the donor), the easy applicability and low cost of the procedure and the wide target scope, also covering the synthesis of disaccharides and other non-trivial glycosides with applicable potential. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Computed Properties of C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Computed Properties of C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Effects of benorylate and impacina on the metabolism of cultured hepatocytes was written by Castell, J. V. M.;Montoya, A.;Larrauri, A.;Lopez, P.;Gomez-L., J.. And the article was included in Xenobiotica in 1985.HPLC of Formula: 5003-48-5 The following contents are mentioned in the article:

The effects of benorylate (I) [5003-48-5] and impacina (II) [99040-04-7] on liver metabolism was evaluated by adapting the use of cultured adult rat hepatocytes as a biol. model. Cells were exposed to subtoxic levels of the xenobiotic which was incorporated into the culture media. This was followed by the evaluation in treated cultures of some biochem. functions typical of the liver, namely, gluconeogenesis, glycogen  [9005-79-2] metabolism, synthesis of plasma proteins and ureogenesis, and a comparison was made with nontreated controls. I impaired glucose  [50-99-7] release by hepatocytes to the medium and net accumulation of glycogen was detected. Urea  [57-13-6] production also diminished (20%) in I-treated cells. II significantly increased the synthesis of albumin and transferrin when added at therapeutic levels into the culture medium and did not alter other biochem. functions of the hepatocytes. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5HPLC of Formula: 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.HPLC of Formula: 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Preparation and evaluation of agar/maltodextrin-beeswax emulsion films with various hydrophilic-lipophilic balance emulsifiers was written by Zhang, Rui;Zhai, Xiaosong;Wang, Wentao;Hou, Hanxue. And the article was included in Food Chemistry in 2022.Recommanded Product: 31566-31-1 The following contents are mentioned in the article:

The structural and physicochem. properties of agar/maltodextrin-beeswax films in the presence of three emulsifiers, including glycerol monostearate, sodium stearoyl lactylate, and polysorbate 80 were investigated. SEM revealed that addition of lower hydrophilic-lipophilic balance value emulsifiers produced smaller size and more uniform distribution of beeswax in the film matrix. X-ray diffraction and differential scanning calorimetry indicated that the emulsifiers with lower hydrophilic-lipophilic balance values promoted the compatibility between agar/maltodextrin and beeswax more effectively. The incorporation of different emulsifiers showed diverse impacts on the film network structure and physicochem. properties. Agar/maltodextrin-beeswax-polysorbate 80 film showed maximum stiffness (861.99 MPa). Agar/maltodextrin-beeswax-glycerol monostearate film exhibited the highest tensile strength (26.79 MPa), elongation at break (31.83%), water vapor barrier (7.64 x 10-13 g·m-1·s-1·Pa-1) and oxygen barrier properties (3.82 x 10-17 cm2·s-1·Pa-1), which could be more effective for packaging foods that are prone to oxidize. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1Recommanded Product: 31566-31-1).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Recommanded Product: 31566-31-1

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

GC-MS-based metabolite profiling of wild and in vitro growing plants of Satureja montana L. was written by Vrancheva, Radka;Dincheva, Ivayla;Aneva, Ina;Georgiev, Vasil;Pavlov, Atanas. And the article was included in Comptes Rendus de l’Academie Bulgare des Sciences in 2022.COA of Formula: C21H44O5 The following contents are mentioned in the article:

Satureja montana L. is used as a traditional culinary spice in the Balkan Peninsula cuisine, as well as in the folk and traditional medicine for treatment of different diseases. The supply of secondary metabolites from naturally growing plants has many restrictions, such as biomass availability and variations in the chem. composition, which is most strongly affected by seasonal and environmental- mental factors. These disadvantages could be overcome by cultivating plants in optimized and controlled in vitro conditions. The purpose of the current study was to compare the phytochem. compositions of newly developed in vitro plants and intact plants of S. montana used for production of secondary metabolites. The GC-MS anal. revealed the presence of a number of primary (carbohydrates, amino acids, organic acids and lipids) and secondary metabolites (phenolic acids) with pharmacol. and biol. activities beneficial to humans. The results revealed that in vitro S. montana plants are a potential biotechnol. matrix for the production of valuable biol. active substances for the food, pharmaceutical and cosmetic industries. This study involved multiple reactions and reactants, such as Glyceryl monostearate (cas: 31566-31-1COA of Formula: C21H44O5).

Glyceryl monostearate (cas: 31566-31-1) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.COA of Formula: C21H44O5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of new triazole linked carbohybrids with ROS-mediated toxicity in breast cancer was written by Kumari, Priti;Dubey, Shraddha;Venkatachalapathy, Sneha;Narayana, Chintam;Gupta, Ashish;Sagar, Ram. And the article was included in New Journal of Chemistry in 2019.Recommanded Product: 604-69-3 The following contents are mentioned in the article:

Carbohybrids are an important class of mols. which exhibit diverse biol. activities and are present as structural motifs in many natural products. Two series of new triazole linked N-glycosides of coumarins and quinolones (n = 27) were efficiently synthesized starting from 1-azido-2,3,4,6-tetra-O-acetyl β-D-glucose and 1-azido-2,3,4,6-tetra-O-acetyl β-D-galactose reacting with various 4-O-propargyl coumarins and 4-O-propargyl quinolones in shorter reaction time (30 min) under microwave assisted conditions. Anticancer activity of these newly synthesized triazole linked N-glycosides of coumarins and quinolones was determined in detail through cellular assays against MCF-7 (breast cancer cell line), HepG2 (liver cancer cell line), HCT-116 (colon cancer cell line) and Huh-7.5 cell lines. The selected library member displayed low micromolar (IC₅₀ 10.97μM) and selective toxicity against the breast cancer cell line (MCF-7). Mechanistic studies showed that the anticancer activity of the active compound was because of the generation of reactive oxygen species (ROS). This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Recommanded Product: 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Recommanded Product: 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Divergent Synthesis of Natural Benzyl Salicylate and Benzyl Gentisate Glucosides was written by Fedorova, Dariya D.;Nazarova, Dariya S.;Avetyan, David L.;Shatskiy, Andrey;Belyanin, Maxim L.;Karkas, Markus D.;Stepanova, Elena V.. And the article was included in Journal of Natural Products in 2020.Formula: C16H22O11 The following contents are mentioned in the article:

Herein is reported the first total synthesis of benzyl salicylate and benzyl gentisate glucosides present in various plant species, in particular the Salix genus, such as Populus balsamifera and P. trichocarpa. The method permits the synthesis of several natural phenolic acid derivatives and their glucosides starting from salicylic or gentisic acid. The divergent approach afforded access to three different acetylated glucosides from a common synthetic intermediate. The key step in the total synthesis of naturally occurring glycosides-the selective deacetylation of the sugar moiety-was achieved in the presence of a labile benzyl ester group by employing mild deacetylation conditions. The protocol permitted synthesis of trichocarpine (4 steps, 40% overall yield), isotrichocarpine (3 steps, 51% overall yield), trichoside (6 steps, 40% overall yield), and deoxytrichocarpine (3 steps, 42% overall yield) for the first time (>95% purity). Also, the optimized mild deacetylation conditions allowed synthesis of 2-O-acetylated derivatives of all four glycosides (5-17% overall yield, 90-95% purity), which are rare plant metabolites. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Formula: C16H22O11).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.Formula: C16H22O11

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics