Tag: 300-400

Determination of salicylemia following single and multiple administration of RB 580 (acetoxy-acetamino-phenylbenzoate) and acetylsalicylic acid was written by Melloni, G. F.;Goldberg, D.;Lureti, G. F.;Minoja, G. M.. And the article was included in Gazzetta Medica Italiana in 1978.Application In Synthesis of 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

In 2 groups of patients single and multiple administration of RB 580 [5003-48-5] resulted in higher mean blood levels of acetylsalicylic acid (I) [50-78-2] than in those receiving I. The half lives were 4.6 and 6.1 h for RB 580 and I, resp. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Application In Synthesis of 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Application In Synthesis of 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Synthesis of novel 1,4-naphthoquinone-based molecules by an Ugi-type four-component reaction was written by Rabelo, Waleria F.;Echemendia, Radell. And the article was included in Synthetic Communications in 2019.Recommanded Product: 604-69-3 The following contents are mentioned in the article:

An Ugi-type multicomponent approach for the synthesis of novel 3-substituted 1,4-naphthoquinones e.g., I was described. The process relied on the execution of an enol-Ugi reaction between an enol-3-nitro-1,4-naphthoquinone with different secondary diamines and isocyanides. The novel methodol. showed great chem. efficiency and versatility. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Recommanded Product: 604-69-3).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Recommanded Product: 604-69-3

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Protecting carbohydrates with ethers, acetals and orthoesters under basic conditions was written by Liang, Yang;Pedersen, Christian M.. And the article was included in Organic & Biomolecular Chemistry in 2021.Category: esters-buliding-blocks The following contents are mentioned in the article:

Chlorinated Et and vinyl ethers are introduced at various positions of carbohydrates. Depending on the relative stereochem., vinylethers, acetals or orthoesters are formed under basic conditions. The products are stable, but are easily deprotected after dechlorination. The scope of the intramol. protection is studied using common pentoses and hexoses. This study involved multiple reactions and reactants, such as (2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3Category: esters-buliding-blocks).

(2S,3R,4S,5R,6R)-6-(Acetoxymethyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate (cas: 604-69-3) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Because of their lack of hydrogen-bond-donating ability, esters do not self-associate. Consequently, esters are more volatile than carboxylic acids of similar molecular weight.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Preliminary studies on the absorption of exterylate, benorylate and acetylsalicylic acid was written by Pina, M.;Ortega, P.;Alonso, S.;Armijo, M.. And the article was included in Archivos de Farmacologia y Toxicologia in 1978.HPLC of Formula: 5003-48-5 The following contents are mentioned in the article:

In rats given, intragastrically, acetylsalicylic acid (I) [50-78-2], benorylate [5003-48-5] or eterylate [62992-61-4] (50-100 mg/kg) the maximum levels of free salicylic acid [69-72-7] were detected in plasma at 1, 3-4, and 3-6 h, resp. Apparently, benorylate and eterylate are absorbed more slowly than I. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5HPLC of Formula: 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are also usually derived from carboxylic acids. It may also be obtained by reaction of acid anhydride or acid halides with alcohols or by the reaction of salts of carboxylic acids with alkyl halides. Esterification is the general name for a chemical reaction in which two reactants (typically an alcohol and an acid) form an ester as the reaction product. Esters are common in organic chemistry and biological materials.HPLC of Formula: 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Improved one-pot synthesis of Acetylsalol, Benorilate, and Guacetisal. Prodrugs of aspirin was written by Wang, Zhi-zhong;Ma, Jiang-Yuan. And the article was included in Journal of Chemical and Pharmaceutical Research in 2012.Formula: C17H15NO5 The following contents are mentioned in the article:

Improved, cost-effective and one-pot methods for the synthesis of three aspirin prodrugs (Acetylsalol, Benorilate, Guacetisal) were achieved by using N,N’-carbonyldiimidazole as a coupling reagent. Moreover, the byproduct imidazole as the catalyst promoted the reactions. The procedures are simple and suitable to large-scale manufactures This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Formula: C17H15NO5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Carboxylic acid esters of low molecular weight are colourless, volatile liquids with pleasant odours, slightly soluble in water. Cyclic esters are called lactones, regardless of whether they are derived from an organic or inorganic acid. One example of an organic lactone is γ-valerolactone.Formula: C17H15NO5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

High-performance liquid chromatography systems for the analysis of analgesic and non-steroidal anti-inflammatory drugs in forensic toxicology was written by Stevens, H. M.;Gill, R.. And the article was included in Journal of Chromatography in 1986.HPLC of Formula: 5003-48-5 The following contents are mentioned in the article:

HPLC retention data are presented for >40 analgesic drugs on an ODS-silica packing material to assist in the identification of these compounds Three isocratic eluents prepared from iso-PrOH, HCO₂H, and an aqueous phosphate buffer were used. One eluent was used for the anal. of paracetamol (I) [103-90-2] in whole blood. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5HPLC of Formula: 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters perform as high-grade solvents for a broad array of plastics, plasticizers, resins, and lacquers, and are one of the largest classes of synthetic lubricants on the commercial market. Polyesters are important plastics, with monomers linked by ester moieties. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.HPLC of Formula: 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

NBS and Br₃CCOCBr₃ as highly efficient catalysts for the chemoselective N-tert-butyloxycarbonylation of amines was written by Chantarasriwong, Oraphin;Jiangchareon, Banphot;Putra, Christian Kurnia;Suwankrua, Winai;Chavasiri, Warinthorn. And the article was included in Tetrahedron Letters in 2016.Category: esters-buliding-blocks The following contents are mentioned in the article:

N-Bromosuccinimide (NBS) and hexabromoacetone (Br₃CCOCBr₃) are new and efficient catalysts for the chemoselective N-tert-butyloxycarbonylation of aliphatic and aromatic amines. This novel, simple, and effective method for the preparation of N-Boc protected products proceeds in good to excellent yields with short reaction times at room temperature This study involved multiple reactions and reactants, such as tert-Butyl N-(4-(2-(((tert-butoxy)carbonyl)amino)ethyl)phenyl)carbamate (cas: 1823291-67-3Category: esters-buliding-blocks).

tert-Butyl N-(4-(2-(((tert-butoxy)carbonyl)amino)ethyl)phenyl)carbamate (cas: 1823291-67-3) belongs to esters. Volatile esters with characteristic odours are used in synthetic flavours, perfumes, and cosmetics. Certain volatile esters are used as solvents for lacquers, paints, and varnishes. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

TFAA-H₃PO₄ mediated rapid and single-step synthesis of mutual prodrugs of paracetamol and NSAIDs was written by Kankanala, Kavitha;Billur, Ramya;Reddy, Vangala Ranga;Mukkanti, Khagga;Pal, Sarbani. And the article was included in Green Chemistry Letters and Reviews in 2012.HPLC of Formula: 5003-48-5 The following contents are mentioned in the article:

A clean and operationally simple method was developed for the preparation of mutual prodrugs using paracetamol and various nonsteroidal anti-inflammatory drugs. The methodol. involves use of trifluoroacetic anhydride/H₃PO₄ in acetonitrile and a variety of mutual prodrugs was prepared in good yields by this single-step C-O bond forming reaction. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5HPLC of Formula: 5003-48-5).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Liquid esters of low volatility serve as softening agents for resins and plastics. Esters also include many industrially important polymers. Polymethyl methacrylate is a glass substitute sold under the names Lucite and Plexiglas; polyethylene terephthalate is used as a film (Mylar) and as textile fibres sold as Terylene, Fortrel, and Dacron.HPLC of Formula: 5003-48-5

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

In vitro anti-leishmanial activity of compounds in current clinical use for unrelated diseases was written by Neal, R. A.;Allen, S.. And the article was included in Drugs under Experimental and Clinical Research in 1988.Quality Control of 4-Acetamidophenyl 2-acetoxybenzoate The following contents are mentioned in the article:

Drugs in current clin. use were tested for anti-Leishmania activity using an in vitro infected macrophage assay. Out of almost 400 compounds tested, over 100 were active. The most active compounds showed ED₅₀ values below 1 μM. The active compounds should be tested in in vivo systems. They made lead to the development of new antileishmanials. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Quality Control of 4-Acetamidophenyl 2-acetoxybenzoate).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters are widespread in nature and are widely used in industry. In nature, fats are in general triesters derived from glycerol and fatty acids. Esters are responsible for the aroma of many fruits, including apples, durians, pears, bananas, pineapples, and strawberries. Many esters have the potential for conformational isomerism, but they tend to adopt an s-cis (or Z) conformation rather than the s-trans (or E) alternative, due to a combination of hyperconjugation and dipole minimization effects. The preference for the Z conformation is influenced by the nature of the substituents and solvent, if present. Lactones with small rings are restricted to the s-trans (i.e. E) conformation due to their cyclic structure.Quality Control of 4-Acetamidophenyl 2-acetoxybenzoate

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics

Liquid chromatography-mass spectrometry for component determination in Citramon tablets was written by Klyuev, N. A.;Pochelov, I. I.;Petrenko, V. V.. And the article was included in Fiziologichno Aktivni Rechovini in 2002.Category: esters-buliding-blocks The following contents are mentioned in the article:

The authors developed a new method for the determination of components of Citramon tablets by liquid chromatog.-mass spectrometry method. The impurities such as 2-hydroxybenzoic acid Et ester, 2-hydroxybenzoic acid, a salicylic acid dimer were identified by the method developed. Quant. determination was carried out by normalization of areas on the chromatogram. This study involved multiple reactions and reactants, such as 4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5Category: esters-buliding-blocks).

4-Acetamidophenyl 2-acetoxybenzoate (cas: 5003-48-5) belongs to esters. Esters typically have a pleasant smell; those of low molecular weight are commonly used as fragrances and are found in essential oils and pheromones. Acyl chlorides and acid anhydrides alcoholysis is another way to produce esters. Acyl chlorides and acid anhydrides react with alcohols to produce esters. Anydrous conditions are recommended since both acyl chlorides and acid anhydrides react with water.Category: esters-buliding-blocks

Referemce:
Ester – Wikipedia,
Ester – an overview | ScienceDirect Topics